Published in J Immunol on December 03, 2010
Interleukin-4- and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease. Annu Rev Immunol (2013) 2.47
SHIP1 intrinsically regulates NK cell signaling and education, resulting in tolerance of an MHC class I-mismatched bone marrow graft in mice. J Immunol (2015) 0.89
SHIP-deficient mice develop spontaneous intestinal inflammation and arginase-dependent fibrosis. Am J Pathol (2011) 0.86
CCAAT/enhancer-binding protein alpha (C/EBPalpha) is critical for interleukin-4 expression in response to FcepsilonRI receptor cross-linking. J Biol Chem (2011) 0.84
Pharmacological targeting of phosphoinositide lipid kinases and phosphatases in the immune system: success, disappointment, and new opportunities. Front Immunol (2012) 0.82
Understanding the roles of basophils: breaking dawn. Immunology (2012) 0.81
Signaling pathways activated by a protease allergen in basophils. Proc Natl Acad Sci U S A (2014) 0.78
iNKT Cells Are Responsible for the Apoptotic Reduction of Basophils That Mediate Th2 Immune Responses Elicited by Papain in Mice Following γPGA Stimulation. PLoS One (2016) 0.77
All Trans Retinoic Acid, Transforming Growth Factor β and Prostaglandin E2 in Mouse Plasma Synergize with Basophil-Secreted Interleukin-4 to M2 Polarize Murine Macrophages. PLoS One (2016) 0.75
SHIP represses the generation of alternatively activated macrophages. Immunity (2005) 7.41
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nat Med (2005) 6.58
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci (2011) 4.21
LPS-induced upregulation of SHIP is essential for endotoxin tolerance. Immunity (2004) 3.13
The molecular basis of vascular lumen formation in the developing mouse aorta. Dev Cell (2009) 3.08
Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Rep (2012) 2.83
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
A critical role for Stat3 signaling in immune tolerance. Immunity (2003) 2.41
Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation. Immunity (2012) 2.34
Novel functions of the CD34 family. J Cell Sci (2008) 2.18
Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML. Blood (2013) 2.12
Small, mobile FcepsilonRI receptor aggregates are signaling competent. Immunity (2009) 2.08
PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling. Nat Immunol (2002) 2.03
Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A (2007) 2.02
Influence of SHIP on the NK repertoire and allogeneic bone marrow transplantation. Science (2002) 1.94
Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI. Proc Natl Acad Sci U S A (2003) 1.94
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Res (2004) 1.90
FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin. Immunity (2007) 1.90
Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal. Blood (2009) 1.89
Development, migration, and survival of mast cells. Immunol Res (2006) 1.78
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. Cancer Cell (2009) 1.78
IgE stimulates human and mouse arterial cell apoptosis and cytokine expression and promotes atherogenesis in Apoe-/- mice. J Clin Invest (2011) 1.77
Mast cells in tumor growth: angiogenesis, tissue remodelling and immune-modulation. Biochim Biophys Acta (2009) 1.75
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts. Nat Med (2002) 1.71
The 19-kDa Mycobacterium tuberculosis protein induces macrophage apoptosis through Toll-like receptor-2. J Immunol (2003) 1.66
The role of podocalyxin in health and disease. J Am Soc Nephrol (2009) 1.66
TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci Signal (2010) 1.61
Multiple pathways involved in the biosynthesis of anandamide. Neuropharmacology (2007) 1.59
IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis. Cell Metab (2012) 1.56
Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion. J Biol Chem (2004) 1.49
Protein kinase C-delta is a negative regulator of antigen-induced mast cell degranulation. Mol Cell Biol (2002) 1.44
Expansion of myeloid suppressor cells in SHIP-deficient mice represses allogeneic T cell responses. J Immunol (2004) 1.42
Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. Blood (2005) 1.41
Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum. J Exp Med (2009) 1.41
Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells. J Immunol (2004) 1.40
Imaging breast cancer morphology using probe-based confocal laser endomicroscopy: towards a real-time intraoperative imaging tool for cavity scanning. Breast Cancer Res Treat (2015) 1.39
Induced SHIP deficiency expands myeloid regulatory cells and abrogates graft-versus-host disease. J Immunol (2007) 1.34
A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation. Cancer Res (2011) 1.33
Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta. J Biol Chem (2004) 1.32
G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells. Blood (2003) 1.30
Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function. J Exp Med (2010) 1.30
Small-molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells. Blood (2007) 1.28
Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3. Proc Natl Acad Sci U S A (2005) 1.28
The CD34-related molecule podocalyxin is a potent inducer of microvillus formation. PLoS One (2007) 1.25
Positive and negative regulation of mast cell activation by Lyn via the FcepsilonRI. J Immunol (2005) 1.25
CD34 facilitates the development of allergic asthma. Blood (2007) 1.25
SHIP1 inhibition increases immunoregulatory capacity and triggers apoptosis of hematopoietic cancer cells. J Immunol (2010) 1.25
The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn. Blood (2007) 1.24
SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis. J Leukoc Biol (2011) 1.23
Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma. Am J Pathol (2004) 1.22
CD34 and CD43 inhibit mast cell adhesion and are required for optimal mast cell reconstitution. Immunity (2005) 1.22
SHIP negatively regulates IgE + antigen-induced IL-6 production in mast cells by inhibiting NF-kappa B activity. J Immunol (2002) 1.21
SHIP is required for a functional hematopoietic stem cell niche. Blood (2008) 1.20
Activin/TGF-beta induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP. Nat Cell Biol (2002) 1.19
Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell. J Immunol (2007) 1.17
Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. J Immunol (2007) 1.16
Regulation of myeloproliferation and M2 macrophage programming in mice by Lyn/Hck, SHIP, and Stat5. J Clin Invest (2008) 1.16
SHIP represses the generation of IL-3-induced M2 macrophages by inhibiting IL-4 production from basophils. J Immunol (2009) 1.16
CD34 is a specific marker of mature murine mast cells. Exp Hematol (2002) 1.16
Early divergence of Fc epsilon receptor I signals for receptor up-regulation and internalization from degranulation, cytokine production, and survival. J Immunol (2004) 1.16
SHIP limits immunoregulatory capacity in the T-cell compartment. Blood (2009) 1.15
The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia. Blood (2006) 1.14
Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood (2005) 1.14
Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation. J Biol Chem (2006) 1.13
The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma. Clin Exp Metastasis (2012) 1.13
Role of galectin-3 in mast cell functions: galectin-3-deficient mast cells exhibit impaired mediator release and defective JNK expression. J Immunol (2006) 1.12
The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity. J Biol Chem (2003) 1.12
Control of the hippo pathway by Set7-dependent methylation of Yap. Dev Cell (2013) 1.11
CD34 is a key regulator of hematopoietic stem cell trafficking to bone marrow and mast cell progenitor trafficking in the periphery. Microcirculation (2009) 1.11
A novel approach to analyze gesture forms and functions in spontaneous oral discourse production of normal speakers. Procedia Soc Behav Sci (2012) 1.10
The role of SHIP in macrophages. Front Biosci (2007) 1.10
SHIP, SHIP2, and PTEN activities are regulated in vivo by modulation of their protein levels: SHIP is up-regulated in macrophages and mast cells by lipopolysaccharide. Exp Hematol (2003) 1.09
SHIP1 negatively regulates proliferation of osteoclast precursors via Akt-dependent alterations in D-type cyclins and p27. J Immunol (2006) 1.09
Role of SHIP in cancer. Exp Hematol (2010) 1.09
SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation. Blood (2006) 1.08
Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer. Mol Med (2012) 1.08
Derivation and characterization of murine alternatively activated (M2) macrophages. Methods Mol Biol (2009) 1.08
SHIP down-regulates FcepsilonR1-induced degranulation at supraoptimal IgE or antigen levels. J Immunol (2005) 1.08
Deregulated expression of LRBA facilitates cancer cell growth. Oncogene (2004) 1.08
Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production. J Immunol (2010) 1.07