Published in PLoS One on February 21, 2007
Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer. Br J Cancer (2011) 1.64
A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. J Cell Biol (2011) 1.52
CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy. PLoS One (2016) 1.40
Requirement of podocalyxin in TGF-beta induced epithelial mesenchymal transition. PLoS One (2011) 1.25
Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer. BMC Cancer (2012) 1.17
Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer. Br J Cancer (2013) 1.16
The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma. Clin Exp Metastasis (2012) 1.13
Podocalyxin is a marker of poor prognosis in colorectal cancer. BMC Cancer (2014) 0.99
Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy. Breast Cancer Res (2015) 0.92
"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92
The emerging importance of α-L-fucose in human breast cancer: a review. Am J Transl Res (2011) 0.89
A familiar stranger: CD34 expression and putative functions in SVF cells of adipose tissue. World J Stem Cells (2013) 0.88
A comparative study of two PODXL antibodies in 840 colorectal cancer patients. BMC Cancer (2014) 0.88
Podocalyxin Is a Marker of Poor Prognosis in Pancreatic Ductal Adenocarcinoma. PLoS One (2015) 0.88
Podocalyxin regulates murine lung vascular permeability by altering endothelial cell adhesion. PLoS One (2014) 0.87
Formation of microvilli and phosphorylation of ERM family proteins by CD43, a potent inhibitor for cell adhesion: cell detachment is a potential cue for ERM phosphorylation and organization of cell morphology. Cell Adh Migr (2011) 0.83
Regulation of cell shape and adhesion by CD34. Cell Adh Migr (2013) 0.82
The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135. J Cell Biol (2015) 0.81
p120-catenin controls contractility along the vertical axis of epithelial lateral membranes. J Cell Sci (2015) 0.81
The cell surface mucin podocalyxin regulates collective breast tumor budding. Breast Cancer Res (2016) 0.80
ZO-1 and ZO-2 are required for extra-embryonic endoderm integrity, primitive ectoderm survival and normal cavitation in embryoid bodies derived from mouse embryonic stem cells. PLoS One (2014) 0.76
Stem cell marker TRA-1-60 is expressed in foetal and adult kidney and upregulated in tubulo-interstitial disease. Histochem Cell Biol (2010) 0.76
Podocalyxin-like and RNA-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer: a validatory study. Biomark Res (2017) 0.75
Aberrant epigenetic regulators control expansion of human CD34+ hematopoietic stem/progenitor cells. Front Genet (2013) 0.75
Role of CD34 family members in lumen formation in the developing kidney. Dev Biol (2016) 0.75
Podocalyxin-like protein, linked to poor prognosis of pancreatic cancers, promotes cell invasion by binding to gelsolin. Cancer Sci (2016) 0.75
Epithelial-mesenchymal transitions: twist in development and metastasis. Cell (2004) 7.14
Identification and characterization of podocalyxin--the major sialoprotein of the renal glomerular epithelial cell. J Cell Biol (1984) 3.91
Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell (2006) 3.28
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Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells. J Cell Biol (1997) 2.51
Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin. J Exp Med (2001) 2.45
Ezrin-radixin-moesin (ERM)-binding phosphoprotein 50 organizes ERM proteins at the apical membrane of polarized epithelia. Proc Natl Acad Sci U S A (2004) 2.31
Espin cross-links cause the elongation of microvillus-type parallel actin bundles in vivo. J Cell Biol (2003) 2.31
Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. J Clin Invest (2001) 2.26
NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin. J Biol Chem (1998) 2.25
Villin induces microvilli growth and actin redistribution in transfected fibroblasts. Cell (1989) 2.19
The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annu Rev Physiol (2006) 2.18
ERM proteins: from cellular architecture to cell signaling. Biol Cell (2000) 2.15
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. J Cell Biol (2005) 2.06
The co-workers of actin filaments: from cell structures to signals. Nat Rev Mol Cell Biol (2004) 2.01
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Res (2004) 1.90
Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34. J Exp Med (1998) 1.81
Biogenesis of podocalyxin--the major glomerular sialoglycoprotein--in the newborn rat kidney. Eur J Cell Biol (1989) 1.74
Expression of podocalyxin inhibits cell-cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells. Mol Biol Cell (2000) 1.70
The glomerular epithelial cell anti-adhesin podocalyxin associates with the actin cytoskeleton through interactions with ezrin. J Am Soc Nephrol (2001) 1.63
NHERF: targeting and trafficking membrane proteins. Am J Physiol Renal Physiol (2001) 1.61
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50). J Biol Chem (2003) 1.60
Molecular cloning and characterization of human podocalyxin-like protein. Orthologous relationship to rabbit PCLP1 and rat podocalyxin. J Biol Chem (1997) 1.58
Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes. J Cell Sci (1999) 1.54
Podocalyxin activates RhoA and induces actin reorganization through NHERF1 and Ezrin in MDCK cells. J Am Soc Nephrol (2004) 1.52
Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. Blood (2005) 1.41
Thrombomucin, a novel cell surface protein that defines thrombocytes and multipotent hematopoietic progenitors. J Cell Biol (1997) 1.39
In vivo enzymatic removal of alpha 2-->6-linked sialic acid from the glomerular filtration barrier results in podocyte charge alteration and glomerular injury. Lab Invest (1996) 1.22
Sulfate contributes to the negative charge of podocalyxin, the major sialoglycoprotein of the glomerular filtration slits. Proc Natl Acad Sci U S A (1991) 1.21
Glomerular epithelial alterations resulting from sialic acid surface coat removal. Kidney Int (1979) 1.20
A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting. J Biol Chem (2002) 1.17
E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer? Breast Cancer Res (2001) 1.17
Cell surface proteins of chicken hematopoietic progenitors, thrombocytes and eosinophils detected by novel monoclonal antibodies. Leukemia (1992) 1.13
Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene. Proc Natl Acad Sci U S A (2006) 1.09
Drosophila melanogaster Cad99C, the orthologue of human Usher cadherin PCDH15, regulates the length of microvilli. J Cell Biol (2005) 1.07
PDZ domain-mediated interaction of rabbit podocalyxin and Na(+)/H(+) exchange regulatory factor-2. Am J Physiol Renal Physiol (2002) 1.07
Podocalyxin in rat platelets and megakaryocytes. Am J Pathol (1999) 1.06
Binding of monoclonal antibodies to glomerular endothelium, slit membranes, and epithelium after in vivo injection. Localization of antigens and bound IgGs by immunoelectron microscopy. Am J Pathol (1990) 1.04
Epithelial polyanion (podocalyxin) is found on the sides but not the soles of the foot processes of the glomerular epithelium. Am J Pathol (1986) 1.03
Pattern of expression of the podocalyxin gene in the mouse brain during development. Gene Expr Patterns (2005) 0.88
New functions for the NHERF family of proteins. J Clin Invest (2001) 0.82
Na+/H+ exchanger regulatory factor-1 is a hematopoietic ligand for a subset of the CD34 family of stem cell surface proteins. Stem Cells (2006) 0.82
Influence of cytoplasmic deletions on the filopodia-inducing effect of syndecan-3. Cell Biol Int (2004) 0.80
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell (2002) 5.58
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci (2011) 4.21
The molecular basis of vascular lumen formation in the developing mouse aorta. Dev Cell (2009) 3.08
Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Rep (2012) 2.83
Hematopoietic stem cells do not engraft with absolute efficiencies. Blood (2005) 2.81
Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet. Stem Cells (2009) 2.48
Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation. Immunity (2012) 2.34
Novel functions of the CD34 family. J Cell Sci (2008) 2.18
Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A (2007) 2.02
Discovery of a sensory organ that coordinates lunge feeding in rorqual whales. Nature (2012) 1.91
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Res (2004) 1.90
Mast cells in tumor growth: angiogenesis, tissue remodelling and immune-modulation. Biochim Biophys Acta (2009) 1.75
Attaching and effacing pathogen-induced tight junction disruption in vivo. Cell Microbiol (2006) 1.73
The role of podocalyxin in health and disease. J Am Soc Nephrol (2009) 1.66
Gap junction hemichannels contribute to the generation of diarrhoea during infectious enteric disease. Gut (2009) 1.56
Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen. Infect Immun (2007) 1.46
Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. Blood (2005) 1.41
Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease. Hum Mol Genet (2005) 1.39
Regulation of BRCA1 expression and its relationship to sporadic breast cancer. Breast Cancer Res (2002) 1.35
Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells. J Cell Sci (2003) 1.27
CD34 facilitates the development of allergic asthma. Blood (2007) 1.25
Cortactin (CTTN), N-WASP (WASL), and clathrin (CLTC) are present at podosome-like tubulobulbar complexes in the rat testis. Biol Reprod (2008) 1.24
Tubulobulbar complexes are intercellular podosome-like structures that internalize intact intercellular junctions during epithelial remodeling events in the rat testis. Biol Reprod (2008) 1.23
CD34 and CD43 inhibit mast cell adhesion and are required for optimal mast cell reconstitution. Immunity (2005) 1.22
The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility. J Lipid Res (2004) 1.16
CD34 is a specific marker of mature murine mast cells. Exp Hematol (2002) 1.16
Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin. J Biol Chem (2010) 1.15
The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma. Clin Exp Metastasis (2012) 1.13
Evidence that tight junctions are disrupted due to intimate bacterial contact and not inflammation during attaching and effacing pathogen infection in vivo. Infect Immun (2006) 1.13
CD34 is a key regulator of hematopoietic stem cell trafficking to bone marrow and mast cell progenitor trafficking in the periphery. Microcirculation (2009) 1.11
A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctions. Cell Motil Cytoskeleton (2002) 1.11
Evidence that tubulobulbar complexes in the seminiferous epithelium are involved with internalization of adhesion junctions. Biol Reprod (2004) 1.09
Podocalyxin: a marker of blasts in acute leukemia. Am J Clin Pathol (2005) 1.06
Perinatal antibiotic treatment affects murine microbiota, immune responses and allergic asthma. Gut Microbes (2013) 1.05
The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient. PLoS One (2008) 1.04
Testicular degeneration in Huntington disease. Neurobiol Dis (2007) 1.04
Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation. Exp Cell Res (2004) 1.04
Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability. J Immunol (2009) 1.03
SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens. PLoS Pathog (2013) 1.02
ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway. Cancer Res (2010) 1.02
The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression. Differentiation (2007) 1.02
Bone marrow-derived mast cells accumulate in the central nervous system during inflammation but are dispensable for experimental autoimmune encephalomyelitis pathogenesis. J Immunol (2009) 1.01
Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One (2010) 1.01
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol (2011) 1.00
Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis. Oncogene (2004) 0.98
SHIP1 is a repressor of mast cell hyperplasia, cytokine production, and allergic inflammation in vivo. J Immunol (2009) 0.97
The metalloprotease-disintegrin ADAM8 is essential for the development of experimental asthma. Am J Respir Crit Care Med (2010) 0.96
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer Res (2010) 0.95
Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells. Org Lett (2005) 0.95
CD34 is required for infiltration of eosinophils into the colon and pathology associated with DSS-induced ulcerative colitis. Am J Pathol (2010) 0.95
A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis. Exp Hematol (2010) 0.94
Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling. Gastroenterology (2010) 0.94
Primary ovarian mucinous carcinoma of intestinal type: significance of pattern of invasion and immunohistochemical expression profile in a series of 31 cases. Int J Gynecol Pathol (2010) 0.93
CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration. Stem Cells (2011) 0.92
Influence of host irradiation on long-term engraftment by CD34-deficient hematopoietic stem cells. Blood (2007) 0.92
The deubiquitinase activity of the Salmonella pathogenicity island 2 effector, SseL, prevents accumulation of cellular lipid droplets. Infect Immun (2011) 0.90
Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes. J Biol Chem (2011) 0.90
CD34 expression by mast cells: of mice and men. Blood (2005) 0.89
A familiar stranger: CD34 expression and putative functions in SVF cells of adipose tissue. World J Stem Cells (2013) 0.88
Stem cells, inflammation and allergy. Allergy Asthma Clin Immunol (2009) 0.88
The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Res (2004) 0.88
The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viability. Mol Biol Cell (2011) 0.88
Regulated expression of cyclic AMP-dependent protein kinase A reveals an influence on cell size and the secretion of virulence factors in Cryptococcus neoformans. Mol Microbiol (2012) 0.88
Gelsolin--evidence for a role in turnover of junction-related actin filaments in Sertoli cells. J Cell Sci (2002) 0.88
A novel subcellular machine contributes to basal junction remodeling in the seminiferous epithelium. Biol Reprod (2013) 0.87
Internalization of adhesion junction proteins and their association with recycling endosome marker proteins in rat seminiferous epithelium. Reproduction (2011) 0.87
Focal adhesion proteins Zyxin and Vinculin are co-distributed at tubulobulbar complexes. Spermatogenesis (2012) 0.87
SHIP represses Th2 skewing by inhibiting IL-4 production from basophils. J Immunol (2010) 0.86
CD34 is required for dendritic cell trafficking and pathology in murine hypersensitivity pneumonitis. Am J Respir Crit Care Med (2011) 0.86
Opposing roles for CD34 in B16 melanoma tumor growth alter early stage vasculature and late stage immune cell infiltration. PLoS One (2011) 0.86
The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer. Reprod Biol Endocrinol (2003) 0.86
A kinesin is present at unique sertoli/spermatid adherens junctions in rat and mouse testes. Biol Reprod (2007) 0.86
Methyltransferase G9A regulates T cell differentiation during murine intestinal inflammation. J Clin Invest (2014) 0.86
CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans. Mol Biol Cell (2013) 0.86
Novel muscle and connective tissue design enables high extensibility and controls engulfment volume in lunge-feeding rorqual whales. J Exp Biol (2013) 0.85
Desmosomes are unaltered during infections by attaching and effacing pathogens. Anat Rec (Hoboken) (2007) 0.85
Branchial mitochondria-rich cells in the dogfish Squalus acanthias. Comp Biochem Physiol A Mol Integr Physiol (2002) 0.84
Prenatal ethanol exposure delays the onset of spermatogenesis in the rat. Alcohol Clin Exp Res (2013) 0.84
Epithelio-mesenchymal transition in a neoplastic ovarian epithelial hybrid cell line. Differentiation (2004) 0.84
Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Mol Cancer Ther (2005) 0.83
Na+/H+ exchanger regulatory factor-1 is a hematopoietic ligand for a subset of the CD34 family of stem cell surface proteins. Stem Cells (2006) 0.82
Organellar (Na+, K+)/H+ exchanger NHE7 regulates cell adhesion, invasion and anchorage-independent growth of breast cancer MDA-MB-231 cells. Oncol Rep (2011) 0.82
Requirement for core 2 O-glycans for optimal resistance to helminth infection. PLoS One (2013) 0.81
Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis. BMC Microbiol (2009) 0.81
Avinosol, a meroterpenoid-nucleoside conjugate with antiinvasion activity isolated from the marine sponge Dysidea sp. Org Lett (2006) 0.80
Microenvironmental regulation of BRCA1 gene expression by c-Jun and Fra2 in premalignant human ovarian surface epithelial cells. Mol Cancer Res (2013) 0.80
Podocalyxin selectively marks erythroid-committed progenitors during anemic stress but is dispensable for efficient recovery. Exp Hematol (2008) 0.80
Differential effects of cellular fibronectin and plasma fibronectin on ovarian cancer cell adhesion, migration, and invasion. In Vitro Cell Dev Biol Anim (2003) 0.80
Cortactin depletion results in short tubulobulbar complexes and spermiation failure in rat testes. Biol Open (2012) 0.80
Enrichment and disassembly of ectoplasmic specializations in the rat testis. Methods Mol Biol (2007) 0.79
CD34 mediates intestinal inflammation in Salmonella-infected mice. Cell Microbiol (2010) 0.79
The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm. Am J Respir Cell Mol Biol (2015) 0.79