Published in EMBO Rep on December 03, 2010
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PTK 7 is a transforming gene and prognostic marker for breast cancer and nodal metastasis involvement. PLoS One (2014) 0.93
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The PTK7-related transmembrane proteins off-track and off-track 2 are co-receptors for Drosophila Wnt2 required for male fertility. PLoS Genet (2014) 0.85
Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells. Cell Commun Signal (2014) 0.83
Protein tyrosine kinase 7 (PTK7) as a predictor of lymph node metastases and a novel prognostic biomarker in patients with prostate cancer. Int J Mol Sci (2014) 0.83
PTK7 regulates Id1 expression in CD44-high glioma cells. Neuro Oncol (2014) 0.81
Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis. J Biol Chem (2014) 0.81
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Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration. Elife (2016) 0.80
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Planar cell polarity of the kidney. Exp Cell Res (2014) 0.80
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Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer. PLoS One (2015) 0.78
Isolation of Human Colon Stem Cells Using Surface Expression of PTK7. Stem Cell Reports (2015) 0.78
Serial analysis of gene expression in the chicken otocyst. J Assoc Res Otolaryngol (2011) 0.77
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Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer. Cancers (Basel) (2016) 0.77
Catalytically defective receptor protein tyrosine kinase PTK7 enhances invasive phenotype by inducing MMP-9 through activation of AP-1 and NF-κB in esophageal squamous cell carcinoma cells. Oncotarget (2016) 0.75
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BMP inhibition initiates neural induction via FGF signaling and Zic genes. Proc Natl Acad Sci U S A (2009) 1.21
The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein. Virus Res (2008) 1.20
Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis. Biochem Biophys Res Commun (2008) 1.19
Regulation of LKB1/STRAD localization and function by E-cadherin. Curr Biol (2008) 1.18
Basolateral targeting by leucine-rich repeat domains in epithelial cells. EMBO Rep (2003) 1.17
Scrib regulates PAK activity during the cell migration process. Hum Mol Genet (2008) 1.17
BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders. Blood (2013) 1.16
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A polymorphism of EGFR extracellular domain is associated with progression free-survival in metastatic colorectal cancer patients receiving cetuximab-based treatment. BMC Cancer (2008) 1.13
The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome. Blood (2010) 1.11
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An essential role for transcription before the MBT in Xenopus laevis. Dev Biol (2011) 1.06
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Interaction between Erbin and a Catenin-related protein in epithelial cells. J Biol Chem (2001) 1.05
Analysis of splicing patterns by pyrosequencing. Nucleic Acids Res (2009) 1.04
Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes. Mol Cell Proteomics (2008) 1.04
Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase. Gene (2004) 1.04
Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway. Development (2010) 1.04
Erbin regulates mitogen-activated protein (MAP) kinase activation and MAP kinase-dependent interactions between Merlin and adherens junction protein complexes in Schwann cells. J Biol Chem (2005) 1.02
Oncogenic functions of PTK6 are enhanced by its targeting to plasma membrane but abolished by its targeting to nucleus. J Biochem (2009) 1.02
Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH. J Biol Chem (2002) 1.00
Syndecan-2 functions as a docking receptor for pro-matrix metalloproteinase-7 in human colon cancer cells. J Biol Chem (2009) 1.00
Characterization of plasma gelsolin as a substrate for matrix metalloproteinases. Proteomics (2006) 0.99
Erbin regulates NRG1 signaling and myelination. Proc Natl Acad Sci U S A (2009) 0.98
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1. J Biol Chem (2010) 0.97
An absolute role of the PKC-dependent NF-kappaB activation for induction of MMP-9 in hepatocellular carcinoma cells. Biochem Biophys Res Commun (2003) 0.96
PTK7: a cell polarity receptor with multiple facets. Cell Cycle (2011) 0.95
Erbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta. Dev Cell (2009) 0.95
The LKB1 complex-AMPK pathway: the tree that hides the forest. Fam Cancer (2011) 0.95
TIMP-1 inhibits apoptosis in breast carcinoma cells via a pathway involving pertussis toxin-sensitive G protein and c-Src. Biochem Biophys Res Commun (2003) 0.95
Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metalloproteinase-9 expression in human monocytic U937 cells. Exp Mol Med (2006) 0.94
The human PDZome: a gateway to PSD95-Disc large-zonula occludens (PDZ)-mediated functions. Mol Cell Proteomics (2013) 0.94
Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes. J Proteomics (2011) 0.93
Evidence for a molecular link between the tuberous sclerosis complex and the Crumbs complex. Hum Mol Genet (2007) 0.93
Outcome of acute myeloid leukaemia following myelodysplastic syndrome after azacitidine treatment failure. Br J Haematol (2012) 0.93
Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear. Development (2012) 0.93
Biochemical studies and molecular dynamics simulations of Smad3-Erbin interaction identify a non-classical Erbin PDZ binding. Biochem Biophys Res Commun (2008) 0.93
Probing the opening of the pancreatic lipase lid using site-directed spin labeling and EPR spectroscopy. Biochemistry (2007) 0.93