Published in Diabetologia on December 23, 2010
Obesity and type 2 diabetes: what can be unified and what needs to be individualized? J Clin Endocrinol Metab (2011) 1.63
The metabolically benign and malignant fatty liver. Diabetes (2011) 1.39
Obesity and type 2 diabetes: what can be unified and what needs to be individualized? Diabetes Care (2011) 1.31
Impaired insulin sensitivity and elevated ectopic fat in healthy obese vs. nonobese prepubertal children. Obesity (Silver Spring) (2011) 1.06
Intramyocellular lipid is associated with visceral adiposity, markers of insulin resistance, and cardiovascular risk in prepubertal children: the EPOCH study. J Clin Endocrinol Metab (2012) 0.90
Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liver. Diabetes Care (2013) 0.88
Prepubertal children exposed to concentrated disadvantage: An exploratory analysis of inflammation and metabolic dysfunction. Obesity (Silver Spring) (2016) 0.85
Inverse correlation of serum inflammatory markers with metabolic parameters in healthy, Black and White prepubertal youth. Int J Obes (Lond) (2013) 0.81
1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents. PLoS One (2015) 0.79
Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle. BMC Pediatr (2015) 0.79
MRI chemical shift imaging of the fat content of the pancreas and liver of patients with type 2 diabetes mellitus. Exp Ther Med (2015) 0.78
Fibroblast Growth Factor 21 Suppresses Adipogenesis in Pig Intramuscular Fat Cells. Int J Mol Sci (2015) 0.76
Lower body adipose tissue removal decreases glucose tolerance and insulin sensitivity in mice with exposure to high fat diet. Adipocyte (2014) 0.75
(1)H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity. Obes Sci Pract (2016) 0.75
Banting lecture 1988. Role of insulin resistance in human disease. Diabetes (1988) 33.22
Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA (2010) 23.45
Cellular mechanisms of insulin resistance. J Clin Invest (2000) 12.61
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia (1999) 8.17
Prevalence of fatty liver in children and adolescents. Pediatrics (2006) 7.00
The metabolic syndrome in children and adolescents. Lancet (2007) 5.97
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proc Natl Acad Sci U S A (2009) 5.64
Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity. Metabolism (2001) 3.25
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care (2006) 2.86
Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. Diabetes (1999) 2.86
Failure of adipocyte differentiation causes type II diabetes mellitus? Nat Genet (2000) 2.47
Insulin resistance syndrome in a representative sample of children and adolescents from Quebec, Canada. Int J Obes Relat Metab Disord (2004) 2.26
In vivo determination of intra-myocellular lipids in human muscle by means of localized 1H-MR-spectroscopy. Magn Reson Med (1997) 2.21
Type 2 diabetes mellitus in children and youth: a new epidemic. J Pediatr Endocrinol Metab (2002) 1.89
Relation of triglyceride stores in skeletal muscle cells to central obesity and insulin sensitivity in European and South Asian men. Diabetologia (1999) 1.45
Insulin resistance and whole body energy homeostasis in obese adolescents with fatty liver disease. Am J Physiol Endocrinol Metab (2006) 1.32
Liver steatosis in juvenile obesity: correlations with lipid profile, hepatic biochemical parameters and glycemic and insulinemic responses to an oral glucose tolerance test. Int J Obes Relat Metab Disord (2000) 1.31
Intrahepatic fat accumulation and alterations in lipoprotein composition in obese adolescents: a perfect proatherogenic state. Diabetes Care (2007) 1.30
Evaluation of HOMA and QUICKI as measures of insulin sensitivity in prepubertal children. Pediatr Diabetes (2003) 1.27
Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content. Obesity (Silver Spring) (2008) 1.27
Comparison of metabolic syndrome prevalence using six different definitions in overweight pre-pubertal children enrolled in a weight management study. Int J Obes (Lond) (2006) 1.11
Liver steatosis in obese prepubertal children: a possible role of insulin resistance. Obesity (Silver Spring) (2008) 0.99
Familial, anthropometric, and metabolic associations of intramyocellular lipid levels in prepubertal males. Pediatr Res (2002) 0.87
Feasibility of assessing liver lipid by proton magnetic resonance spectroscopy in healthy normal and overweight prepubertal children. Diabetes Technol Ther (2010) 0.87
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med (1991) 16.81
Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science (1966) 13.12
Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med (1995) 8.51
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians. N Engl J Med (1993) 6.89
Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber. J Clin Invest (1986) 5.18
Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study. Lancet (2001) 4.80
Reactions in vivo and in vitro produced by a soluble substance associated with delayed-type hypersensitivity. Proc Natl Acad Sci U S A (1968) 4.57
Circulating ghrelin levels are decreased in human obesity. Diabetes (2001) 4.28
Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab (2013) 3.88
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest (2001) 3.86
The children's depression inventory: a systematic evaluation of psychometric properties. J Consult Clin Psychol (1984) 3.41
Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev (1999) 3.41
Energy expenditure by doubly labeled water: validation in humans and proposed calculation. Am J Physiol (1986) 3.35
Effects of IL-13 on phenotype, cytokine production, and cytotoxic function of human monocytes. Comparison with IL-4 and modulation by IFN-gamma or IL-10. J Immunol (1993) 3.14
Crude-oil biodegradation via methanogenesis in subsurface petroleum reservoirs. Nature (2007) 3.06
Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ. Am J Physiol (1990) 3.01
Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest (1990) 2.63
D-penicillamine induced Goodpasture's syndrome in Wilson's disease. Ann Intern Med (1975) 2.56
Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography. Proc Natl Acad Sci U S A (1999) 2.55
Studies on the migration inhibitory factor associated with delayed-type hypersensitivity: cytodynamics and specificity. Transplantation (1967) 2.52
Body mass index as a measure of adiposity in children and adolescents: relationship to adiposity by dual energy x-ray absorptiometry and to cardiovascular risk factors. J Clin Endocrinol Metab (2001) 2.52
Is a low leptin concentration, a low resting metabolic rate, or both the expression of the "thrifty genotype"? Results from Mexican Pima Indians. Am J Clin Nutr (1998) 2.42
Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus. Int J Obes Relat Metab Disord (2004) 2.40
Improving public health information: a data quality intervention in KwaZulu-Natal, South Africa. Bull World Health Organ (2011) 2.37
Twenty-four-hour energy expenditure and resting metabolic rate in obese, moderately obese, and control subjects. Am J Clin Nutr (1982) 2.37
Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes. Diabetes Obes Metab (2010) 2.30
Effect of satiation on brain activity in obese and lean women. Obes Res (2001) 2.25
An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians. J Clin Invest (1998) 2.18
Energy expenditure and free-living physical activity in black and white women: comparison before and after weight loss. Am J Clin Nutr (2000) 2.04
Energy metabolism in African Americans: potential risk factors for obesity. Am J Clin Nutr (1999) 2.03
Migration inhibitory factor associated with delayed-type hypersensitivity. Fed Proc (1990) 2.02
Use of dual-energy X-ray absorptiometry in obese individuals. Am J Clin Nutr (1995) 2.02
Insulin resistance associated with lower rates of weight gain in Pima Indians. J Clin Invest (1991) 2.02
Familial dependence of the resting metabolic rate. N Engl J Med (1986) 1.94
Specific suppression of tumor growth by isolated peritoneal macrophages from immunized mice. J Immunol (1965) 1.90
Effects of glucocorticoids on energy metabolism and food intake in humans. Am J Physiol (1996) 1.86
Higher sedentary energy expenditure in patients with Huntington's disease. Ann Neurol (2000) 1.86
Differential brain responses to satiation in obese and lean men. Diabetes (2000) 1.81
Body weight gain in free-living Pima Indians: effect of energy intake vs expenditure. Int J Obes Relat Metab Disord (2003) 1.79
Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians. Am J Hum Genet (1998) 1.78
Reconstitution of the [4Fe-4S] cluster in FNR and demonstration of the aerobic-anaerobic transcription switch in vitro. Biochem J (1996) 1.78
A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM. Diabetologia (1995) 1.70
Epidemiological study of respiratory disease in workers exposed to polyvinylchloride dust. Thorax (1980) 1.69
Racial differences in the relation between blood pressure and insulin resistance. N Engl J Med (1991) 1.68
Subcortical hyperintensities on magnetic resonance imaging: clinical correlates and prognostic significance in patients with severe depression. Biol Psychiatry (1995) 1.67
Relationship between serum resistin concentrations and insulin resistance in nonobese, obese, and obese diabetic subjects. J Clin Endocrinol Metab (2004) 1.63
Prostatic calculi: a review. Prostate (1985) 1.62
Isolation and cultivation in vitro of macrophages from various sources in the mouse. Am J Pathol (1966) 1.59
Energy intake and physical activity in Pima Indians: comparison with energy expenditure measured by doubly-labeled water. Obes Res (1994) 1.58
Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine. Obes Res (1999) 1.58
Daily energy expenditure in Mexican and USA Pima indians: low physical activity as a possible cause of obesity. Int J Obes Relat Metab Disord (2000) 1.55
The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J Immunol (2000) 1.54
Jun N-terminal kinase in rheumatoid arthritis. J Pharmacol Exp Ther (1999) 1.52
A comparative study of different means of assessing long-term energy expenditure in humans. Am J Physiol (1996) 1.52
Antihyperglycemic activity of Tarralin, an ethanolic extract of Artemisia dracunculus L. Phytomedicine (2005) 1.51
Determinants of energy expenditure and fuel utilization in man: effects of body composition, age, sex, ethnicity and glucose tolerance in 916 subjects. Int J Obes Relat Metab Disord (1999) 1.51
Energy metabolism after 2 y of energy restriction: the biosphere 2 experiment. Am J Clin Nutr (2000) 1.50
Fat necrosis and inflammatory pseudotumor due to endoscopic tattooing of the colon with india ink. Gastrointest Endosc (1991) 1.50
Energy expenditure, fat oxidation, and body weight regulation: a study of metabolic adaptation to long-term weight change. J Clin Endocrinol Metab (2000) 1.49
Energy cost of physical activity on a metabolic ward in relationship to obesity. Am J Clin Nutr (1991) 1.48
Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia (2004) 1.43
Energy expenditure before and during energy restriction in obese patients. Am J Clin Nutr (1985) 1.42
Familial thrombosis: inherited deficiency of antithrombin III. Br Med J (1978) 1.40
Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians. Hum Mol Genet (1998) 1.40
Energy metabolism, fuel selection and body weight regulation. Int J Obes (Lond) (2008) 1.39
Plasminogen activator inhibitor (PAI-1) in plasma and platelets. Br J Haematol (1988) 1.38
Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes. J Exp Med (1997) 1.37
Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes. Int J Exp Diabetes Res (2000) 1.36
Effect of muscle glycogen depletion on in vivo insulin action in man. J Clin Invest (1983) 1.35
Sulfite:Cytochrome c oxidoreductase from Thiobacillus novellus. Purification, characterization, and molecular biology of a heterodimeric member of the sulfite oxidase family. J Biol Chem (2000) 1.31
31P MRS measurement of mitochondrial function in skeletal muscle: reliability, force-level sensitivity and relation to whole body maximal oxygen uptake. NMR Biomed (2000) 1.30
Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals. J Gerontol A Biol Sci Med Sci (1999) 1.29
Determinants of total daily energy expenditure: variability in physical activity. Am J Clin Nutr (1994) 1.29
NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes. J Immunol (2001) 1.28
Fasting hyperinsulinemia is a predictor of increased body weight gain and obesity in Pima Indian children. Diabetes (1997) 1.26
Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling. Development (2003) 1.26
Increase in insulin action and fat oxidation after treatment with CL 316,243, a highly selective beta3-adrenoceptor agonist in humans. Diabetes (1998) 1.26
Relation of the migration inhibitory factor (MIF) to delayed-type hypersensitivity reactions. Ann N Y Acad Sci (1970) 1.26
Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab (2011) 1.25
Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians. Am J Hum Genet (1997) 1.25
Lower daily energy expenditure as measured by a respiratory chamber in subjects with spinal cord injury compared with control subjects. Am J Clin Nutr (1998) 1.25
Thermic effect of food in humans: methods and results from use of a respiratory chamber. Am J Clin Nutr (1995) 1.24
Evaluation of the strength-size relationship in vivo using various muscle size indices. Med Sci Sports Exerc (2000) 1.24
Influence of age, sex, and insulin on osteoblast function: osteoblast dysfunction in diabetes mellitus. J Clin Endocrinol Metab (1995) 1.24
Short-term energy balance: relationship with protein, carbohydrate, and fat balances. Am J Physiol (1988) 1.23
Divalent metal binding properties of the methionyl aminopeptidase from Escherichia coli. Biochemistry (2000) 1.23
Evaluation of body fat in fatter and leaner 10-y-old African American and white children: the Baton Rouge Children's Study. Am J Clin Nutr (2001) 1.22
Changes in antihemophilic factor (AHF, factor 8) procoagulant activity and AHF-like antigen in normal pregnancy, and following exercise and pneumoencephalography. J Lab Clin Med (1972) 1.21
Reduced insulin secretion: an independent predictor of body weight gain. J Clin Endocrinol Metab (1995) 1.21
Effect of restraint stress on food intake and body weight is determined by time of day. Am J Physiol (1997) 1.20
Spontaneous physical activity and obesity: cross-sectional and longitudinal studies in Pima Indians. Am J Physiol (1992) 1.19
Energy expenditure of elite female runners measured by respiratory chamber and doubly labeled water. J Appl Physiol (1985) (1992) 1.17
Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group. Am J Hum Genet (1997) 1.17
Demonstration of delayed hypersensitivity to soluble antigens of chemically induced tumors by inhibition of macrophage migration. Proc Natl Acad Sci U S A (1969) 1.17
Self-administration of cocaine analogs by rats. Psychopharmacology (Berl) (1999) 1.17
Guidelines for the use of thrombolytic therapy. Haemostasis and Thrombosis Task Force of the British Committee for Standards in Haematology. Blood Coagul Fibrinolysis (1995) 1.16
Comparison of the validity of anthropometric and bioelectric impedance equations to assess body composition in adolescent girls. Int J Body Compos Res (2007) 1.16