Published in J Immunol on December 27, 2010
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The early interferon response to rotavirus is regulated by PKR and depends on MAVS/IPS-1, RIG-I, MDA-5, and IRF3. J Virol (2011) 1.30
Rotavirus immune responses and correlates of protection. Curr Opin Virol (2012) 1.11
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The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway. J Virol (2012) 0.92
Rotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domain. J Virol (2013) 0.91
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Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells. PLoS One (2014) 0.89
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Sensing and control of bluetongue virus infection in epithelial cells via RIG-I and MDA5 helicases. J Virol (2012) 0.88
Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activation. J Virol (2013) 0.88
Viral interactions with the host and microbiota in the intestine. Curr Opin Immunol (2012) 0.87
Characterization of rotavirus RNAs that activate innate immune signaling through the RIG-I-like receptors. PLoS One (2013) 0.87
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Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3. Virology (2015) 0.84
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Multistrain probiotic modulation of intestinal epithelial cells' immune response to a double-stranded RNA ligand, poly(i·c). Appl Environ Microbiol (2013) 0.83
Apoptosis, Necrosis, and Necroptosis in the Gut and Intestinal Homeostasis. Mediators Inflamm (2015) 0.83
Differential Expression Profile of Chicken Embryo Fibroblast DF-1 Cells Infected with Cell-Adapted Infectious Bursal Disease Virus. PLoS One (2015) 0.81
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Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome. Sci Rep (2016) 0.80
Viral Mimicry to Usurp Ubiquitin and SUMO Host Pathways. Viruses (2015) 0.79
Over-expression of mitochondrial antiviral signaling protein inhibits coxsackievirus B3 infection by enhancing type-I interferons production. Virol J (2012) 0.79
Intraluminal administration of poly I:C causes an enteropathy that is exacerbated by administration of oral dietary antigen. PLoS One (2014) 0.79
When your cap matters: structural insights into self vs non-self recognition of 5' RNA by immunomodulatory host proteins. Curr Opin Struct Biol (2016) 0.78
Rotavirus Controls Activation of the 2'-5'-Oligoadenylate Synthetase/RNase L Pathway Using at Least Two Distinct Mechanisms. J Virol (2015) 0.77
Rotavirus NSP4 Triggers Secretion of Proinflammatory Cytokines from Macrophages via Toll-Like Receptor 2. J Virol (2013) 0.77
Immunobiotic Bifidobacteria Strains Modulate Rotavirus Immune Response in Porcine Intestinal Epitheliocytes via Pattern Recognition Receptor Signaling. PLoS One (2016) 0.77
Inflammatory and oxidative stress in rotavirus infection. World J Virol (2016) 0.76
The viral dsRNA analogue poly (I:C) induces necrotizing enterocolitis in neonatal mice. Pediatr Res (2015) 0.76
TLR3 signaling is downregulated by a MAVS isoform in epithelial cells. Cell Immunol (2016) 0.75
Mutations in toll-like receptor 3 are associated with elevated levels of rotavirus-specific IgG antibodies in IgA-deficient but not IgA-sufficient individuals. Clin Vaccine Immunol (2013) 0.75
Intestinal Innate Antiviral Immunity and Immunobiotics: Beneficial Effects against Rotavirus Infection. Front Immunol (2016) 0.75
Cherry Valley Ducks Mitochondrial Antiviral-Signaling Protein-Mediated Signaling Pathway and Antiviral Activity Research. Front Immunol (2016) 0.75
Interferon-Lambda: A Potent Regulator of Intestinal Viral Infections. Front Immunol (2017) 0.75
The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation. EMBO J (2017) 0.75
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell (2004) 15.82
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science (2005) 5.25
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The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion. Nat Med (2003) 3.85
Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies. Infect Immun (2004) 2.32
IkappaB-kinasebeta-dependent NF-kappaB activation provides radioprotection to the intestinal epithelium. Proc Natl Acad Sci U S A (2004) 2.12
Opposing functions of IKKbeta during acute and chronic intestinal inflammation. Proc Natl Acad Sci U S A (2008) 1.90
Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol (2005) 1.86
Cell differentiation is a key determinant of cathelicidin LL-37/human cationic antimicrobial protein 18 expression by human colon epithelium. Infect Immun (2002) 1.80
Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infect Immun (2004) 1.77
Loss of liver E-cadherin induces sclerosing cholangitis and promotes carcinogenesis. Proc Natl Acad Sci U S A (2014) 1.55
Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell Microbiol (2002) 1.54
Central importance of immunoglobulin A in host defense against Giardia spp. Infect Immun (2002) 1.54
Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. Gastroenterology (2003) 1.51
Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA. Biochemistry (2007) 1.36
Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation. J Exp Med (2011) 1.33
Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo. Cell Microbiol (2006) 1.29
Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells. Cell Microbiol (2002) 1.22
Cationic liposome-nucleic acid complexes for gene delivery and silencing: pathways and mechanisms for plasmid DNA and siRNA. Top Curr Chem (2010) 1.20
Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer. Proc Natl Acad Sci U S A (2010) 1.18
Nuclear factor-kappa B activation promotes restitution of wounded intestinal epithelial monolayers. Am J Physiol Cell Physiol (2003) 1.15
Regulated production of the chemokine CCL28 in human colon epithelium. Am J Physiol Gastrointest Liver Physiol (2004) 1.12
GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J Immunol (2013) 1.12
Intestinal mucosal responses to microbial infection. Springer Semin Immunopathol (2005) 1.10
The evaluation of putative virulence factors of Helicobacter pylori for gastroduodenal disease by use of a short-term Mongolian gerbil infection model. J Infect Dis (2002) 1.08
Ikappa B kinasebeta/nuclear factor-kappaB activation controls the development of liver metastasis by way of interleukin-6 expression. Hepatology (2009) 1.07
TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol (2012) 1.07
Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury. J Immunol (2006) 1.06
The association between arteriosclerosis related diseases and diverticular bleeding. Int J Colorectal Dis (2012) 1.04
Ubiquitous production of macrophage migration inhibitory factor by human gastric and intestinal epithelium. Gastroenterology (2002) 1.02
Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase. Hepatology (2011) 1.02
The effect of Helicobacter pylori eradication on reducing the incidence of gastric cancer. J Clin Gastroenterol (2008) 1.02
Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cells. J Immunol (2007) 1.01
A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc Natl Acad Sci U S A (2002) 1.00
SDF-1/CXCL12 regulates cAMP production and ion transport in intestinal epithelial cells via CXCR4. Am J Physiol Gastrointest Liver Physiol (2003) 0.98
Effects of musical experience on different components of MEG responses elicited by sequential piano-tones and chords. J Neurosci (2006) 0.98
Access site-related complications after transradial catheterization can be reduced with smaller sheath size and statins. Cardiovasc Interv Ther (2012) 0.96
GM-CSF: a role in immune and inflammatory reactions in the intestine. Expert Rev Gastroenterol Hepatol (2010) 0.96
Inhibitor of kappaB kinase beta regulates gastric carcinogenesis via interleukin-1alpha expression. Gastroenterology (2010) 0.95
GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen. Cell Host Microbe (2010) 0.94
Chemokine receptor CCR6 transduces signals that activate p130Cas and alter cAMP-stimulated ion transport in human intestinal epithelial cells. Am J Physiol Cell Physiol (2004) 0.94
Helicobacter pylori induces antiapoptosis through buclear factor-kappaB activation. J Infect Dis (2003) 0.94
Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis. PLoS One (2013) 0.93
Helicobacter pylori activates NF-kappaB via the alternative pathway in B lymphocytes. J Immunol (2005) 0.93
Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation. Infect Immun (2012) 0.93
Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes. Proc Natl Acad Sci U S A (2013) 0.92
Gastric cancer risk according to the distribution of intestinal metaplasia and neutrophil infiltration. J Gastroenterol Hepatol (2011) 0.91
Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis. J Gastroenterol (2009) 0.91
The intestinal epithelium is an integral component of a communications network. J Clin Invest (2014) 0.91
Apoptosis signal-regulating kinase 1 regulates colitis and colitis-associated tumorigenesis by the innate immune responses. Gastroenterology (2009) 0.90
Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer. Cancer Sci (2013) 0.90
Apoptosis signal-regulating kinase-1 inhibitor as a potent therapeutic drug for the treatment of gastric cancer. Cancer Sci (2012) 0.90
Diagnostic yield of capsule endoscopy for gastric diseases. Abdom Imaging (2012) 0.89
Relationship between nuclear factor-kappaB activation and virulence factors of Helicobacter pylori in Japanese clinical isolates. J Gastroenterol Hepatol (2002) 0.89
Efficacy of flexible spectral imaging color enhancement on the detection of small intestinal diseases by capsule endoscopy. J Dig Dis (2012) 0.89
Two-dimensional packing of short DNA with nonpairing overhangs in cationic liposome-DNA complexes: from Onsager nematics to columnar nematics with finite-length columns. J Am Chem Soc (2011) 0.88
Expression of Epstein-Barr virus-induced gene 3 and other interleukin-12-related molecules by human intestinal epithelium. Immunology (2004) 0.88
Influence of Helicobacter pylori eradication on the management of type 2 diabetes. Hepatogastroenterology (2012) 0.87
Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells. Carcinogenesis (2013) 0.87
Severe gastric damage caused by button battery ingestion in a 3-month-old infant. J Pediatr Surg (2010) 0.87
Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils. Infect Immun (2007) 0.87
Multisynaptic projections from the ventrolateral prefrontal cortex to the dorsal premotor cortex in macaques - anatomical substrate for conditional visuomotor behavior. Eur J Neurosci (2012) 0.87
Anorectal malformation associated with a perineal protrusion of the rectal mucosa: case presentation. Pediatr Surg Int (2009) 0.85
Can consumers trust web-based information about celiac disease? Accuracy, comprehensiveness, transparency, and readability of information on the internet. Interact J Med Res (2012) 0.85
Motor and non-motor projections from the cerebellum to rostrocaudally distinct sectors of the dorsal premotor cortex in macaques. Eur J Neurosci (2010) 0.85
Reduced expression of RAS protein activator like-1 in gastric cancer. Int J Cancer (2011) 0.85
Helicobacter pylori activates the proto-oncogene c-fos through SRE transactivation. Biochem Biophys Res Commun (2002) 0.84
Significance of serial real-time PCR monitoring of EBV genome load in living donor liver transplantation. Clin Transplant (2002) 0.84
Origins of multisynaptic projections from the basal ganglia to rostrocaudally distinct sectors of the dorsal premotor area in macaques. Eur J Neurosci (2010) 0.83
Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to link inflammation and tumorigenesis. Mol Med Rep (2011) 0.81
NF-kappaB and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection. World J Gastroenterol (2005) 0.81
Randomized controlled trial comparing the efficacy of mosapride plus omeprazole combination therapy to omeprazole monotherapy in gastroesophageal reflux disease. J Dig Dis (2014) 0.81
Recanalized umbilical vein as a conduit for mesenterico/porto-Rex bypass for patients with extrahepatic portal vein obstruction. Pediatr Surg Int (2010) 0.80
Successful treatment of early-stage jejunum adenocarcinoma by endoscopic mucosal resection using double-balloon endoscopy: a case report. Diagn Ther Endosc (2012) 0.79
Clinical relevance of Helicobacter pylori sabA genotype in Japanese clinical isolates. J Gastroenterol Hepatol (2007) 0.79
Altered composition of fatty acids exacerbates hepatotumorigenesis during activation of the phosphatidylinositol 3-kinase pathway. J Hepatol (2011) 0.79
The immunopathogenesis of celiac disease reveals possible therapies beyond the gluten-free diet. Semin Immunopathol (2012) 0.78
Factors affecting in-hospital mortality in patients with lower gastrointestinal tract bleeding: a retrospective study using a national database in Japan. J Gastroenterol (2014) 0.78
[NF-kappaB and MAPK-signaling pathways contribute to the gene expression and host response induced by Helicobacter pylori infection]. Nihon Rinsho (2005) 0.78
Neutrophil infiltration and the distribution of intestinal metaplasia is associated with metachronous gastric cancer following endoscopic submucosal dissection. Can J Gastroenterol Hepatol (2015) 0.78
Prognostic Significance of Peripheral Microvascular Endothelial Dysfunction in Heart Failure With Reduced Left Ventricular Ejection Fraction. Circ J (2015) 0.77
Differential roles of ASK1 and TAK1 in Helicobacter pylori-induced cellular responses. Infect Immun (2013) 0.77
Papillary carcinoma with extensive squamous metaplasia arising from thyroglossal duct cyst in an 11-year-old girl: significance of differentiation from squamous cell carcinoma: a case report. J Pediatr Surg (2011) 0.76
Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer. Int J Oncol (2011) 0.76
Multisynaptic projections from the ventrolateral prefrontal cortex to hand and mouth representations of the monkey primary motor cortex. Neurosci Res (2013) 0.76
Celiac disease pathogenesis: the plot thickens. Gastroenterology (2002) 0.76
Relationship between inter-arm blood pressure differences and future cardiovascular events in coronary artery disease. J Hypertens (2015) 0.75
Mucosal inflammation in celiac disease: interleukin-15 meets transforming growth factor beta-1. Gastroenterology (2007) 0.75
Low-Normal Serum Sodium and Heart Failure-Related Events in Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction. Circ J (2015) 0.75
Efficacy and safety of faropenem in eradication therapy of Helicobacter pylori. Helicobacter (2007) 0.75
[Biomarkers of reactive oxygen species]. Nihon Rinsho (2016) 0.75
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Clinical significance of brachial-ankle pulse-wave velocity in patients with heart failure with preserved left ventricular ejection fraction. J Hypertens (2017) 0.75
Sonographic detection of a patency capsule prior to capsule endoscopy: case report. J Clin Ultrasound (2014) 0.75
Multiple intestinal atresia and congenital bilateral perisylvian syndrome in a surviving monochorionic twin with intrauterine death of the co-twin. J Pediatr Surg (2010) 0.75