Published in Science on December 07, 1990
Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex. J Exp Med (1991) 2.33
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc Natl Acad Sci U S A (1991) 2.26
Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture. J Exp Med (1993) 1.77
Specificity and flexibility in thymic selection. Nature (1994) 1.72
Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide. J Exp Med (1992) 1.61
Serum angiotensin-1 converting enzyme activity processes a human immunodeficiency virus 1 gp160 peptide for presentation by major histocompatibility complex class I molecules. J Exp Med (1992) 1.46
Antigen-dependent and -independent Ca2+ responses triggered in T cells by dendritic cells compared with B cells. J Exp Med (1998) 1.46
Peptide influences the folding and intracellular transport of free major histocompatibility complex class I heavy chains. J Exp Med (1995) 1.38
Extracellular processing of peptide antigens that bind class I major histocompatibility molecules. J Exp Med (1992) 1.32
Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. PLoS One (2011) 1.32
The CD8+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I. J Exp Med (1994) 1.29
Major histocompatibility complex class I-specific and -restricted killing of beta 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1992) 1.28
Purification and characterization of a naturally processed hepatitis B virus peptide recognized by CD8+ cytotoxic T lymphocytes. J Clin Invest (1996) 1.20
Comparison of cell lines deficient in antigen presentation reveals a functional role for TAP-1 alone in antigen processing. J Exp Med (1994) 1.18
Low temperature and peptides favor the formation of class I heterodimers on RMA-S cells at the cell surface. Proc Natl Acad Sci U S A (1991) 1.15
Susceptibility to measles virus-induced encephalitis in mice correlates with impaired antigen presentation to cytotoxic T lymphocytes. J Virol (1993) 1.12
Solution binding of an antigenic peptide to a major histocompatibility complex class I molecule and the role of beta 2-microglobulin. Proc Natl Acad Sci U S A (1992) 1.07
Direct delivery of exogenous MHC class I molecule-binding oligopeptides to the endoplasmic reticulum of viable cells. Proc Natl Acad Sci U S A (1997) 1.05
Serum proteases alter the antigenicity of peptides presented by class I major histocompatibility complex molecules. Proc Natl Acad Sci U S A (1992) 1.01
Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules. J Exp Med (1995) 1.00
The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide. Proc Natl Acad Sci U S A (1997) 0.99
Anchoring pockets in human histocompatibility complex leukocyte antigen (HLA) class I molecules: analysis of the conserved B ("45") pocket of HLA-B27. J Exp Med (1992) 0.99
Evidence for a conformational change in a class II major histocompatibility complex molecule occurring in the same pH range where antigen binding is enhanced. J Exp Med (1996) 0.92
Analysis of the association of peptides of optimal length to class I molecules on the surface of cells. Proc Natl Acad Sci U S A (1992) 0.90
A recombinant, soluble, single-chain class I major histocompatibility complex molecule with biological activity. Proc Natl Acad Sci U S A (1992) 0.88
Herpes simplex virus-specific human cytotoxic T-cell colonies expressing either gamma delta or alpha beta T-cell receptor: role of accessory molecules on HLA-unrestricted killing of virus-infected targets. Immunology (1995) 0.87
Heat-aggregated noninfectious influenza virus induces a more balanced CD8(+)-T-lymphocyte immunodominance hierarchy than infectious virus. J Virol (2003) 0.85
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin. Hum Genet (2013) 0.84
A naturally processed mitochondrial self-peptide in complex with thymic MHC molecules functions as a selecting ligand for a viral-specific T cell receptor. J Exp Med (2001) 0.82
Physical and functional association of the major histocompatibility complex class I heavy chain alpha3 domain with the transporter associated with antigen processing. J Exp Med (1998) 0.81
Evolution and comparative analysis of the bat MHC-I region. Sci Rep (2016) 0.78
The class I-b molecule Qa-1 forms heterodimers with H-2Ld and a novel 50-kD glycoprotein encoded centromeric to I-E beta. J Exp Med (1995) 0.78
Ganglioside expression in tissues of mice lacking beta2-microglobulin. Clin Exp Immunol (2002) 0.77
The Implication and Significance of Beta 2 Microglobulin: A Conservative Multifunctional Regulator. Chin Med J (Engl) (2016) 0.76
Monte Carlo study of the effect of beta 2-microglobulin on the binding cleft of the HLA-A2 complex. Protein Sci (1994) 0.75
An in vitro study of the dynamic features of the major histocompatibility complex class I complex relevant to its role as a versatile peptide-receptive molecule. Proc Natl Acad Sci U S A (1997) 0.75
Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain. Immunogenetics (2004) 0.75
Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization. J Immunol (1980) 6.69
CD8(+) T cell-mediated spontaneous diabetes in neonatal mice. J Immunol (1996) 3.02
Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A (1998) 2.71
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects. J Clin Invest (1995) 2.66
Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen. J Exp Med (2001) 2.49
Oscillating behavior of carbohydrate granule formation and dinitrogen fixation in the cyanobacterium Cyanothece sp. strain ATCC 51142. J Bacteriol (1994) 2.48
The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors. Science (1992) 2.41
Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex. J Exp Med (1991) 2.33
Unicellular, aerobic nitrogen-fixing cyanobacteria of the genus Cyanothece. J Bacteriol (1993) 2.22
Optimal conditions for genetic transformation of the cyanobacterium Anacystis nidulans R2. J Bacteriol (1984) 2.17
Organization and Function of Chlorophyll in Membranes of Cyanobacteria during Iron Starvation. Plant Physiol (1983) 2.13
Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity. J Immunol (1998) 2.10
Targeting p53 as a general tumor antigen. Proc Natl Acad Sci U S A (1995) 2.09
Effect of iron deficiency and iron restoration on ultrastructure of Anacystis nidulans. J Bacteriol (1983) 2.03
Bacterial RNA isolation with one hour centrifugation in a table-top ultracentrifuge. Biotechniques (1990) 1.87
Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigens. J Immunol (1999) 1.86
Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells. Eur J Immunol (1992) 1.83
Classification and nomenclature of viruses of cyanobacteria. Intervirology (1983) 1.83
Transcriptional and translational regulation of nitrogenase in light-dark- and continuous-light-grown cultures of the unicellular cyanobacterium Cyanothece sp. strain ATCC 51142. J Bacteriol (1997) 1.82
Isolation and characterization of photosystem I and II membrane particles from the blue-green alga, Synechococcus cedrorum. Biochim Biophys Acta (1978) 1.80
Blood component recalls in the United States. Transfusion (1999) 1.73
Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes. J Exp Med (1997) 1.73
Chlorophyll-protein organization of membranes from the cyanobacterium Anacystis nidulans. Arch Biochem Biophys (1983) 1.69
Metronidazole and the isolation of temperature-sensitive photosynthetic mutants in cyanobacteria. J Bioenerg Biomembr (1980) 1.69
Listeria monocytogenes infects human endothelial cells by two distinct mechanisms. Infect Immun (1995) 1.68
Regulation and sequence of the Synechococcus sp. strain PCC 7942 groESL operon, encoding a cyanobacterial chaperonin. J Bacteriol (1990) 1.64
Recognition by CD8 on cytotoxic T lymphocytes is ablated by several substitutions in the class I alpha 3 domain: CD8 and the T-cell receptor recognize the same class I molecule. Proc Natl Acad Sci U S A (1990) 1.59
Recognition of conformational determinants on H-2 by cytolytic T lymphocytes. Nature (1982) 1.56
Construction of a hybrid plasmid capable of replication in the bacterium Escherichia coli and the cyanobacterium Anacystis nidulans. J Bacteriol (1982) 1.56
Peptide-dependent recognition of H-2Kb by alloreactive cytotoxic T lymphocytes. Nature (1989) 1.52
Serum sickness following streptokinase therapy. AJR Am J Roentgenol (1982) 1.49
Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization. J Exp Med (1996) 1.49
The highly abundant chlorophyll-protein complex of iron-deficient Synechococcus sp. PCC7942 (CP43') is encoded by the isiA gene. Plant Physiol (1993) 1.49
Organization of pigment proteins in the photosystem II complex of the cyanobacterium Anacystis nidulans R2. Proc Natl Acad Sci U S A (1985) 1.45
Influence of Iron Deprivation on the Membrane Composition of Anacystis nidulans. Plant Physiol (1984) 1.44
Ontogeny of T cell tolerance to peripherally expressed antigens. Proc Natl Acad Sci U S A (1999) 1.43
Specific binding of soluble fibrin to macrophages. J Exp Med (1977) 1.42
The induction of cytolytic T lymphocytes with specificity for p-azophenylarsonate coupled syngeneic cells. J Immunol (1978) 1.42
Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously. J Immunol (1999) 1.41
Mitotic recombination between homologous chromosomes generates H-2 somatic cell variants in vitro. Proc Natl Acad Sci U S A (1987) 1.40
A redox-responsive regulator of photosynthesis gene expression in the cyanobacterium Synechocystis sp. Strain PCC 6803. J Bacteriol (2000) 1.38
Monoclonal anti-H-2Kb antibodies detect serological differences between H-2Kb mutants. Immunogenetics (1981) 1.36
Species-restricted interactions between CD8 and the alpha 3 domain of class I influence the magnitude of the xenogeneic response. J Exp Med (1989) 1.35
A hybrid plasmid is a stable cloning vector for the cyanobacterium Anacystis nidulans R2. J Bacteriol (1983) 1.34
Dissection of the B10.D2 anti-H-2Kb cytolytic T lymphocyte receptor repertoire. J Exp Med (1980) 1.29
H-2 hemizygous mutants from a heterozygous cell line: role of mitotic recombination. EMBO J (1983) 1.28
Purification and characterization of an iron stress-induced chlorophyll-protein from the cyanobacterium Anacystis nidulans R2. Biochim Biophys Acta (1988) 1.28
Identification of a carotenoid-binding protein in the cytoplasmic membrane from the heterotrophic cyanobacterium Synechocystis sp. strain PCC6714. J Bacteriol (1986) 1.27
Isolation and Characterization of a Carotenoid-Associated Thylakoid Protein from the Cyanobacterium Anacystis nidulans R2. Plant Physiol (1987) 1.27
Practice parameter for the use of red blood cell transfusions: developed by the Red Blood Cell Administration Practice Guideline Development Task Force of the College of American Pathologists. Arch Pathol Lab Med (1998) 1.26
The Lyt-2 molecule recognizes residues in the class I alpha 3 domain in allogeneic cytotoxic T cell responses. J Exp Med (1988) 1.26
Alloreactive T cells discriminate among a diverse set of endogenous peptides. Proc Natl Acad Sci U S A (1991) 1.25
Deletion mutagenesis in Synechocystis sp. PCC6803 indicates that the Mn-stabilizing protein of photosystem II is not essential for O2 evolution. Biochemistry (1991) 1.25
Infection of Synechococcus cedrorum by the cyanophage AS-1M. I. Ultrastructure of infection and phage assembly. Virology (1976) 1.24
Expression of H-2Db on the cell surface in the absence of detectable beta 2 microglobulin. J Exp Med (1984) 1.23
The sequence alteration associated with a mutational hotspot in p53 protects cells from lysis by cytotoxic T lymphocytes specific for a flanking peptide epitope. J Exp Med (1998) 1.22
DNA sequence and regulation of the gene (cbpA) encoding the 42-kilodalton cytoplasmic membrane carotenoprotein of the cyanobacterium Synechococcus sp. strain PCC 7942. J Bacteriol (1989) 1.21
Arthroplasty of the knee in rheumatoid arthritis and osteoarthritis. A follow-up study after implantation of the McKeever and MacIntosh prostheses. J Bone Joint Surg Am (1972) 1.21
Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas. J Immunol (2000) 1.18
Recognition of influenza-infected cells by cytolytic T lymphocyte clones: determinant selection by class I restriction elements. J Immunol (1983) 1.18
Expression of hemopoietic histocompatibility antigens on H-2-loss variants of F1 hybrid lymphoma cells: evidence consistent with trans gene regulation. J Immunol (1987) 1.18
Scintigraphic detection of atherosclerotic lesions and venous thrombi in man by indium-111-labelled autologous platelets. Lancet (1978) 1.17
Lipoteichoic acids in Lactobacillus strains that colonize the mouse gastric epithelium. Appl Environ Microbiol (1986) 1.16
Studies on the mechanism of enzymatic DNA elongation by Escherichia coli DNA polymerase II. J Mol Biol (1976) 1.16
Alpha-1-antitrypsin deficiency. High prevalence in the St. Louis area determined by direct population screening. Am Rev Respir Dis (1989) 1.15
Monoclonal antibodies to murine cell surface antigens. I. Lyt-1.1. J Immunol (1980) 1.15
Participation of the major histocompatibility complex in antibody recognition of viral antigens expressed on infected cells. J Exp Med (1982) 1.14
Membrane Development in the Cyanobacterium, Anacystis nidulans, during Recovery from Iron Starvation. Plant Physiol (1985) 1.14
Defective CD8+ T cell peripheral tolerance in nonobese diabetic mice. J Immunol (2001) 1.12
Chlorophyll-protein composition of the thylakoid membrane from Prochlorothrix hollandica, a prokaryote containing chlorophyll b. Eur J Biochem (1987) 1.12
Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes. J Exp Med (1982) 1.11
The composition of the T cell receptor repertoire in nude mice. J Immunol (1987) 1.11
Systemic and local interferon gamma gene delivery to the lungs for treatment of allergen-induced airway hyperresponsiveness in mice. Hum Gene Ther (1999) 1.11
Molecular analysis of an EL4 cell line that expresses H-2Db but not H-2Kb or beta 2-microglobulin. Proc Natl Acad Sci U S A (1985) 1.11
Organization of the thylakoid membrane from the heterotrophic cyanobacterium, Aphanocapsa 6714. Biochim Biophys Acta (1985) 1.10
Nucleotide sequence of the gene from the cyanobacterium Anacystis nidulans R2 encoding the Mn-stabilizing protein involved in photosystem II water oxidation. Proc Natl Acad Sci U S A (1987) 1.10
Pattern of cyanophycin accumulation in nitrogen-fixing and non-nitrogen-fixing cyanobacteria. Arch Microbiol (2001) 1.10
LPP-1 infection of the blue-green alga Plectonema boryanum. I. Electron microscopy. J Virol (1970) 1.08
Infection of Synechococcus cedrorum by the cyanophage AS-1M. III. Cellular metabolism and phage development. Virology (1976) 1.08
Co-engagement of CD8 with the T cell receptor is required for negative selection. Nature (1991) 1.07
Retroviral insertional mutagenesis of a target allele in a heterozygous murine cell line. Proc Natl Acad Sci U S A (1985) 1.07
The use of HLA A2.1/p53 peptide tetramers to visualize the impact of self tolerance on the TCR repertoire. J Immunol (2000) 1.06
Detection of mouse alloantibodies by rosetting with protein A-coated sheep red blood cells. Transplantation (1978) 1.05
Cloning, nucleotide sequence, and mutagenesis of a gene (irpA) involved in iron-deficient growth of the cyanobacterium Synechococcus sp. strain PCC7942. J Bacteriol (1988) 1.05
Infection of Synechococcus cedrorum by the cyanophage AS-1M. II. Protein and DNA synthesis. Virology (1976) 1.04
A Highly Active Oxygen-Evolving Photosystem II Preparation from the Cyanobacterium Anacystis nidulans. Plant Physiol (1984) 1.04
Triton X-114 phase fractionation of membrane proteins of the cyanobacterium Anacystis nidulans R2. Arch Biochem Biophys (1984) 1.02
Molecular interactions required for triggering alloantigen-specific cytolytic T lymphocytes. J Immunol (1989) 1.02
Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus. J Immunol (1999) 1.02
Isolation and characterization of a cyanophage infecting the unicellular blue-green algae A. nidulans and S. cedrorum. Virology (1976) 1.01
Phycobilisome-associated glycoproteins in the cyanobacterium Anacystis nidulans R 2. FEBS Lett (1987) 1.01
Identification of iron-responsive, differential gene expression in the cyanobacterium Synechocystis sp. strain PCC 6803 with a customized amplification library. J Bacteriol (2000) 1.01
Scintigraphic detection of carotid atherosclerosis with indium-111-labeled autologous platelets. Circulation (1980) 1.00
Transcriptional and translational regulation of photosystem I and II genes in light-dark- and continuous-light-grown cultures of the unicellular cyanobacterium Cyanothece sp. strain ATCC 51142. J Bacteriol (1998) 1.00
Influence of the major histocompatibility complex on the repertoire of allospecific cytolytic T lymphocytes. J Exp Med (1982) 1.00
T-cell and B-cell responses to viral antigens at the clonal level. Annu Rev Immunol (1983) 0.99
Macromolecular complexes formed as the result of chloramine-T radioiodination of proteins. Int J Appl Radiat Isot (1974) 0.99
Determinants of emergence of antibiotic-resistant Neisseria gonorrhoeae. J Infect Dis (1989) 0.99
Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: a consequence of peptide-dependent allorecognition. Eur J Immunol (1991) 0.99
Oxygen yield and thermoluminescence characteristics of a cyanobacterium lacking the manganese-stabilizing protein of photosystem II. Biochemistry (1992) 0.99