Published in Exp Neurol on January 15, 2011
Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis. J Immunol (2013) 1.01
West Nile virus growth is independent of autophagy activation. Virology (2012) 0.97
Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis. J Virol (2013) 0.93
Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. J Virol (2013) 0.91
Adult human glia, pericytes and meningeal fibroblasts respond similarly to IFNy but not to TGFβ1 or M-CSF. PLoS One (2013) 0.89
Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection. J Virol (2014) 0.86
West nile virus-induced activation of mammalian target of rapamycin complex 1 supports viral growth and viral protein expression. J Virol (2014) 0.85
Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection. J Neurovirol (2011) 0.85
Reovirus-mediated induction of ADAR1 (p150) minimally alters RNA editing patterns in discrete brain regions. Mol Cell Neurosci (2014) 0.81
HSV targeting of the host phosphatase PP1α is required for disseminated disease in the neonate and contributes to pathogenesis in the brain. Proc Natl Acad Sci U S A (2015) 0.80
Activation of innate immune responses in the central nervous system during reovirus myelitis. J Virol (2012) 0.79
Slice culture modeling of central nervous system (CNS) viral infection. Methods Mol Biol (2013) 0.75
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A (1998) 16.04
A simple method for organotypic cultures of nervous tissue. J Neurosci Methods (1991) 14.18
Organotypic slice cultures: a technique has come of age. Trends Neurosci (1997) 4.05
Mechanism of toxicity in rotenone models of Parkinson's disease. J Neurosci (2003) 3.30
Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis (2002) 2.71
Flavivirus encephalitis. N Engl J Med (2004) 2.69
Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's. Herpes (2004) 1.98
Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis. J Virol (1997) 1.90
Caspase 3-dependent cell death of neurons contributes to the pathogenesis of West Nile virus encephalitis. J Virol (2006) 1.86
Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts. Hepatology (1998) 1.64
Proinflammatory cytokines and chemokines in humans with Japanese encephalitis. J Infect Dis (2004) 1.48
Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics. Curr Neuropharmacol (2007) 1.44
Burden of neuroinfectious diseases on the neurology service in a tertiary care center. Neurology (2008) 1.44
Markers for neuronal degeneration in organotypic slice cultures. Brain Res Brain Res Protoc (1999) 1.34
Recombinant Semliki Forest virus and Sindbis virus efficiently infect neurons in hippocampal slice cultures. Proc Natl Acad Sci U S A (1999) 1.30
Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors. J Virol (1999) 1.30
Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis (2008) 1.28
Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors. J Neurovirol (2002) 1.23
Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo. J Virol (2004) 1.18
Development of kainic acid and N-methyl-D-aspartic acid toxicity in organotypic hippocampal cultures. Exp Neurol (1995) 1.15
Neuronal cell death in alphavirus encephalomyelitis. Curr Top Microbiol Immunol (2005) 1.12
Minocycline inhibits West Nile virus replication and apoptosis in human neuronal cells. J Antimicrob Chemother (2007) 1.11
Minocycline delays disease onset and mortality in reovirus encephalitis. Exp Neurol (2005) 1.11
Regional differences in viral growth and central nervous system injury correlate with apoptosis. J Virol (2004) 1.08
Herpes simplex virus type 1-induced encephalitis has an apoptotic component associated with activation of c-Jun N-terminal kinase. J Neurovirol (2003) 1.06
Inhibition of apoptosis prevents West Nile virus induced cell death. BMC Microbiol (2007) 1.02
Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol (2007) 1.01
Predictive value of serum interleukin-6 level in influenza virus-associated encephalopathy. Neurology (2001) 1.01
A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection. J Neurosci (2009) 1.01
Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis. J Infect Dis (2002) 1.01
Functional validation of adult hippocampal organotypic cultures as an in vitro model of brain injury. Brain Res (2004) 0.98
Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. J Virol (2009) 0.97
The roles of caspase-3 and bcl-2 in chemically-induced apoptosis but not necrosis of renal epithelial cells. Oncogene (1999) 0.97
Secretion of the chemokine interleukin-8 during Japanese encephalitis virus infection. J Med Microbiol (2000) 0.96
JAK-STAT signaling pathways are activated in the brain following reovirus infection. J Neurovirol (2007) 0.95
Mechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation. Viral Immunol (2005) 0.95
Paraquat leads to dopaminergic neural vulnerability in organotypic midbrain culture. Neurosci Res (2003) 0.94
Acute encephalopathy associated with influenza A infection in adults. Emerg Infect Dis (2010) 0.94
A refined in vitro model to study inflammatory responses in organotypic membrane culture of postnatal rat hippocampal slices. J Neuroinflammation (2005) 0.93
The control of seizure-like activity in the rat hippocampal slice. Biophys J (2003) 0.93
Role of LRP in TGFbeta2-mediated neuronal uptake of Abeta and effects on memory. J Neurosci Res (2004) 0.92
Gene expression in the brain during reovirus encephalitis. J Neurovirol (2010) 0.92
Neurotropism of herpes simplex virus type 1 in brain organ cultures. J Gen Virol (2006) 0.92
Spatiotemporal evidence of apoptosis-mediated ischemic injury in organotypic hippocampal slice cultures. Neurochem Int (2004) 0.91
Seizure, neuron loss, and mossy fiber sprouting in herpes simplex virus type 1-infected organotypic hippocampal cultures. Epilepsia (2004) 0.91
Optical suppression of experimental seizures in rat brain slices. Epilepsia (2009) 0.90
A new experimental model of focal seizures in the entorhinal cortex. Epilepsia (2010) 0.89
Reactivation of latent cytomegalovirus infection in mouse brain cells detected after transfer to brain slice cultures. J Virol (2002) 0.89
Oxidative stress to dopaminergic neurons as models of Parkinson's disease. Ann N Y Acad Sci (2004) 0.89
Caspase-3 activation is required for reovirus-induced encephalitis in vivo. J Neurovirol (2010) 0.89
Serum and cerebrospinal fluid levels of cytokines in acute encephalopathy associated with human herpesvirus-6 infection. Brain Dev (2008) 0.88
Borna disease virus replication in organotypic hippocampal slice cultures from rats results in selective damage of dentate granule cells. J Virol (2005) 0.88
Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner. J Gen Virol (2008) 0.87
Borna disease virus multiplication in mouse organotypic slice cultures is site-specifically inhibited by gamma interferon but not by interleukin-12. J Virol (2004) 0.86
Epileptic seizures induced by N-acetyl-L-aspartate in rats: in vivo and in vitro studies. Brain Res (2000) 0.83
Cytokines and chemokines in viral encephalitis: a clinicoradiological correlation. Neurosci Lett (2010) 0.83
Prognostic value of cerebrospinal fluid cytokine changes in herpes simplex virus encephalitis. Cytokine (2009) 0.82
Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices. Exp Neurol (2003) 0.80
Glucose/oxygen deprivation induces the alteration of synapsin I and phosphosynapsin. Brain Res (2004) 0.80
Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N Engl J Med (2005) 7.54
Does Toll-like receptor 3 play a biological role in virus infections? Virology (2004) 2.73
Naturally acquired West Nile virus encephalomyelitis in transplant recipients: clinical, laboratory, diagnostic, and neuropathological features. Arch Neurol (2004) 2.71
West Nile virus neuroinvasive disease. Ann Neurol (2006) 2.42
Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis. Arch Neurol (2011) 1.83
Herpesvirus infections of the nervous system. Nat Clin Pract Neurol (2007) 1.48
Molecular methods for diagnosis of viral encephalitis. Clin Microbiol Rev (2004) 1.42
Quantitative CSF PCR in Epstein-Barr virus infections of the central nervous system. Ann Neurol (2002) 1.38
MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts. EMBO J (2003) 1.27
Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria. J Biol Chem (2007) 1.26
Dual infections of the central nervous system with Epstein-Barr virus. J Infect Dis (2004) 1.24
Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors. J Neurovirol (2002) 1.23
Bell's palsy--is glucocorticoid treatment enough? N Engl J Med (2007) 1.22
West Nile virus meningoencephalitis. Nat Clin Pract Neurol (2006) 1.22
Progressive multifocal leukoencephalopathy, efalizumab, and immunosuppression: a cautionary tale for dermatologists. Arch Dermatol (2009) 1.19
Apoptosis in animal models of virus-induced disease. Nat Rev Microbiol (2009) 1.19
Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo. J Virol (2004) 1.18
Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels. J Virol (2002) 1.18
Use of PCR for the diagnosis of herpesvirus infections of the central nervous system. J Clin Virol (2002) 1.17
Two distinct phases of virus-induced nuclear factor kappa B regulation enhance tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in virus-infected cells. J Biol Chem (2003) 1.14
JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells. J Virol (2004) 1.13
Minocycline delays disease onset and mortality in reovirus encephalitis. Exp Neurol (2005) 1.11
Recurrent dermatomal vesicular skin lesions: a clue to diagnosis of herpes simplex virus 2 meningitis. Arch Neurol (2003) 1.09
Regional differences in viral growth and central nervous system injury correlate with apoptosis. J Virol (2004) 1.08
The uninvited guest: JC virus infection of neurons in PML. Neurology (2003) 1.05
Reovirus-induced alterations in gene expression related to cell cycle regulation. J Virol (2002) 1.03
Progressive multifocal leukoencephalopathy: can we reduce risk in patients receiving biological immunomodulatory therapies? Ann Neurol (2010) 1.03
Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol (2007) 1.01
Impact of rituximab-associated B-cell defects on West Nile virus meningoencephalitis in solid organ transplant recipients. Clin Transplant (2009) 1.01
Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS. Arch Neurol (2002) 1.01
Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis. J Infect Dis (2002) 1.01
Reovirus-induced alteration in expression of apoptosis and DNA repair genes with potential roles in viral pathogenesis. J Virol (2003) 1.00
West Nile virus growth is independent of autophagy activation. Virology (2012) 0.97
Fas-mediated apoptotic signaling in the mouse brain following reovirus infection. J Virol (2009) 0.97
JAK-STAT signaling pathways are activated in the brain following reovirus infection. J Neurovirol (2007) 0.95
Novel nuclear herniations induced by nuclear localization of a viral protein. J Virol (2004) 0.95
Nonstructural protein sigma1s is a determinant of reovirus virulence and influences the kinetics and severity of apoptosis induction in the heart and central nervous system. J Virol (2005) 0.95
Reovirus infection of the CNS enhances iNOS expression in areas of virus-induced injury. Exp Neurol (2005) 0.94
Neuro-intensive care of patients with acute CNS infections. Neurotherapeutics (2012) 0.94
Progressive multifocal leukoencephalopathy and relapsing-remitting multiple sclerosis: a comparative study. Arch Neurol (2009) 0.93
Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis. J Virol (2013) 0.93
Gene expression in the brain during reovirus encephalitis. J Neurovirol (2010) 0.92
Colorado surveillance program for chronic wasting disease transmission to humans: lessons from 2 highly suspicious but negative cases. Arch Neurol (2007) 0.92
Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons. J Neurochem (2005) 0.91
Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response. J Virol (2013) 0.91
Disrupted glutamate transporter expression in the spinal cord with acute flaccid paralysis caused by West Nile virus infection. J Neuropathol Exp Neurol (2009) 0.90
The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis. J Virol (2011) 0.90
Initial management of acute bacterial meningitis in adults: summary of IDSA guidelines. Rev Neurol Dis (2006) 0.90
Novel approaches and challenges to treatment of central nervous system viral infections. Ann Neurol (2013) 0.90
Caspase-3 activation is required for reovirus-induced encephalitis in vivo. J Neurovirol (2010) 0.89
Through a glass, darkly: cerebrospinal fluid viral load measurements and the pathogenesis of human immunodeficiency virus infection of the central nervous system. Arch Neurol (2002) 0.86
Viral infections of the nervous system, 2002: update on diagnosis and treatment. Arch Neurol (2002) 0.86
Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection. J Neurovirol (2011) 0.85
Experimental reovirus-induced acute flaccid paralysis and spinal motor neuron cell death. J Neuropathol Exp Neurol (2008) 0.83
TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells. Oncogene (2002) 0.81
Critical role for death-receptor mediated apoptotic signaling in viral myocarditis. J Card Fail (2010) 0.81
Down-regulation of cFLIP following reovirus infection sensitizes human ovarian cancer cells to TRAIL-induced apoptosis. Apoptosis (2007) 0.81
North American encephalitic arboviruses. Neurol Clin (2008) 0.81
Issues and updates in emerging neurologic viral infections. Semin Neurol (2011) 0.80
Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity. J Biol Chem (2012) 0.79
Activation of innate immune responses in the central nervous system during reovirus myelitis. J Virol (2012) 0.79
Cardiac cell-specific apoptotic and cytokine responses to reovirus infection: determinants of myocarditic phenotype. J Card Fail (2009) 0.79
Human herpesvirus 6 and multiple sclerosis: the continuing conundrum. J Infect Dis (2003) 0.78
Type 3 reovirus neuroinvasion after intramuscular inoculation: viral genetic determinants of lethality and spinal cord infection. Virology (2002) 0.77
Reduplicative paramnesia in Morvan's syndrome. J Neurol Sci (2007) 0.77
Elevated CSF cytokines in the Jarisch-Herxheimer reaction of general paresis. JAMA Neurol (2013) 0.77
PML therapy: "It's Déjà vu all over again". J Neurovirol (2013) 0.76
Arbovirus Infections. Continuum (Minneap Minn) (2015) 0.76
The 50th birthday of progressive multifocal leukoencephalopathy: New insights into pathogenesis. Ann Neurol (2008) 0.76
Infectious disease - developments in the field of Creutzfeldt-Jakob disease. Rev Neurol Dis (2007) 0.75
Bacterial meningitis: an urgent need for further progress to reduce mortality and morbidity. Neurology (2008) 0.75
Slice culture modeling of central nervous system (CNS) viral infection. Methods Mol Biol (2013) 0.75
Management of acute shingles (herpes zoster). Rev Neurol Dis (2007) 0.75
Donald H. Gilden, MD (1937-2016). Neurology (2016) 0.75
Persistent neurobehavioral signs and symptoms following West Nile fever. J Neuropsychiatry Clin Neurosci (2008) 0.75