Published in Stroke on December 01, 1990
Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells. Biochem J (2006) 1.28
Clinical use and pharmacological properties of selective COX-2 inhibitors. Eur J Clin Pharmacol (2007) 1.03
Rationally designed multitarget agents against inflammation and pain. Curr Med Chem (2013) 0.91
Sulindac compounds facilitate the cytotoxicity of β-lapachone by up-regulation of NAD(P)H quinone oxidoreductase in human lung cancer cells. PLoS One (2014) 0.84
Aspirin-induced Bcl-2 translocation and its phosphorylation in the nucleus trigger apoptosis in breast cancer cells. Exp Mol Med (2013) 0.84
Salicylates inhibit flavivirus replication independently of blocking nuclear factor kappa B activation. J Virol (2001) 0.82
Phyllostachys edulis compounds inhibit palmitic acid-induced monocyte chemoattractant protein 1 (MCP-1) production. PLoS One (2012) 0.82
Luteal insufficiency in first trimester. Indian J Endocrinol Metab (2013) 0.78
Clinical use of aspirin in treatment and prevention of cardiovascular disease. Thrombosis (2011) 0.77
What We Do When We Suppress Fever. Curr Infect Dis Rep (2005) 0.77
Aspirin and other NSAIDs as chemoprevention agents in melanoma. Cancer Prev Res (Phila) (2014) 0.77
Lost in Translation (LiT): IUPHAR Review 6. Br J Pharmacol (2014) 0.76
The quest for medicines, a grand challenge in the twenty-first century. Front Pharmacol (2010) 0.75
Lobolide, a diterpene, blockades the NF-κB pathway and p38 and ERK MAPK activity in macrophages in vitro. Acta Pharmacol Sin (2012) 0.75
Assessment of the luteal phase in stimulated and substituted cycles. Facts Views Vis Obgyn (2009) 0.75
Does administration of non-steroidal anti-inflammatory drug determine morphological changes in adrenal cortex: ultrastructural studies. Protoplasma (2010) 0.75
Aspirin prophylaxis for the prevention of thrombosis: expectations and limitations. Thrombosis (2012) 0.75
To bleed or not to bleed. Is that the question? Br J Clin Pharmacol (2011) 0.75
Hypoestoxide inhibits tumor growth in the mouse CT26 colon tumor model. World J Gastroenterol (2007) 0.75
Drugs which inhibit prostaglandin biosynthesis. Pharmacol Rev (1974) 7.76
Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol (1998) 7.22
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci U S A (1993) 4.82
Regulatory functions of the vascular endothelium. N Engl J Med (1990) 4.72
Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. Prostaglandins (1976) 4.44
Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation. Nature (1979) 4.41
Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids. Nature (1980) 4.29
The importance of phospholipase-A2 in prostaglandin biosynthesis. Biochem Pharmacol (1976) 3.88
Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature (1972) 3.30
A new approach to anti-inflammatory drugs. Biochem Pharmacol (1979) 2.95
The mechanism of action of aspirin. Thromb Res (2003) 2.72
Phospholipase A2 activity of guinea-pig isolated perfused lungs: stimulation, and inhibition by anti-inflammatory steroids. Br J Pharmacol (1978) 2.41
Quantitative determination of prostaglandins and malondialdehyde formed by the arachidonate oxygenase (prostaglandin synthetase) system of bovine seminal vesicle. Prostaglandins (1973) 2.39
New insights into the mode of action of anti-inflammatory drugs. Inflamm Res (1995) 2.29
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol (1999) 1.99
Mobilizing lipocortin 1 in adherent human leukocytes downregulates their transmigration. Nat Med (1996) 1.96
Anti-phospholipase proteins. Prostaglandins (1984) 1.93
Anti-inflammatory lipocortin 1 production by peripheral blood leucocytes in response to hydrocortisone. Lancet (1990) 1.88
The distribution and metabolism of arachidonic acid in rabbit platelets during aggregation and its modification by drugs. Br J Pharmacol (1977) 1.87
Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test. Proc Natl Acad Sci U S A (1989) 1.82
Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat. Br J Pharmacol (1982) 1.74
Inflammatory effects of prostaglandin D2 in rat and human skin. Br J Pharmacol (1976) 1.69
The electronic aggregometer: a novel device for assessing platelet behavior in blood. J Pharmacol Methods (1980) 1.66
Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids. Nature (1976) 1.65
Inhibition of phospholipase. Br Med Bull (1983) 1.65
Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids. Br J Pharmacol (1995) 1.63
Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung. Nature (1987) 1.63
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: effect of lipocortin 1. Proc Natl Acad Sci U S A (1998) 1.60
Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism. Br J Pharmacol (2000) 1.57
Synthesis of 6-keto-PGF1alpha by ram seminal vesicle microsomes. Prostaglandins (1977) 1.57
Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin 1. J Immunol (1993) 1.57
Pharmacodynamic profile of prostacyclin. Am J Cardiol (1995) 1.51
Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Br J Pharmacol (1997) 1.50
Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model. J Leukoc Biol (1998) 1.49
Anti-inflammatory drugs and their mechanism of action. Inflamm Res (1998) 1.48
Rapid reduction of prostaglandin 15-hydroxy dehydrogenase activity in rat tissues after treatment with protein synthesis inhibitors. Br J Pharmacol (1975) 1.48
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. J Exp Med (1997) 1.47
Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. Br J Pharmacol (2008) 1.43
Mechanism of action of nonsteroidal anti-inflammatory drugs. Am J Med (1998) 1.41
Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism. Nature (1976) 1.41
Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody. J Immunol (1993) 1.40
1-phenyl-3-pyrazolidone: an inhibitor of cyclo-oxygenase and lipoxygenase pathways in lung and platelets. Prostaglandins (1978) 1.39
Mediators produced by the endothelial cell. Hypertension (1988) 1.38
Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes. Biochim Biophys Acta (1978) 1.37
Neutrophil interaction with inflamed postcapillary venule endothelium alters annexin 1 expression. Am J Pathol (2001) 1.37
The inhibition by hydrocortisone of prostaglandin biosynthesis in rat peritoneal leucocytes is correlated with intracellular macrocortin levels. Br J Pharmacol (1981) 1.34
Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line. Proc Natl Acad Sci U S A (1992) 1.34
Inhibition of prostaglandin biosynthesis. Biochem Pharmacol (1974) 1.34
Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs. Proc Natl Acad Sci U S A (1999) 1.34
Nociception in cyclooxygenase isozyme-deficient mice. Proc Natl Acad Sci U S A (2000) 1.32
A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats. Br J Pharmacol (1986) 1.31
Leukocyte transmigration, but not rolling or adhesion, is selectively inhibited by dexamethasone in the hamster post-capillary venule. Involvement of endogenous lipocortin 1. J Immunol (1995) 1.30
Relationship between the anti-phospholipase and anti-inflammatory effects of glucocorticoid-induced proteins. Eur J Pharmacol (1984) 1.28
Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery in vitro. Prostaglandins (1987) 1.28
Hydrocortisone and 'macrocortin' inhibit the zymosan-induced release of lyso-PAF from rat peritoneal leucocytes. Life Sci (1985) 1.27
Mechanism of action of anti-inflammatory drugs. Scand J Rheumatol Suppl (1996) 1.25
Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties. J Biol Chem (1981) 1.25
Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat. Proc Natl Acad Sci U S A (1995) 1.24
Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface. FASEB J (2006) 1.21
Effects of modulators of arachidonic acid metabolism on the synthesis and release of slow-reacting substance of anaphylaxis. Br J Pharmacol (1979) 1.21
Human annexin 1 is highly expressed during the differentiation of the epithelial cell line A 549: involvement of nuclear factor interleukin 6 in phorbol ester induction of annexin 1. Cell Growth Differ (1998) 1.20
POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation. J Immunol (1999) 1.20
Glucocorticoid-and non-glucocorticoid induction of lipocortins (annexins) 1 and 2 in rat peritoneal leucocytes in vivo. Br J Pharmacol (1993) 1.19
Mechanism of action of antiinflammatory drugs. Int J Tissue React (1998) 1.18
Annexin I is stored within gelatinase granules of human neutrophil and mobilized on the cell surface upon adhesion but not phagocytosis. Cell Biol Int (2000) 1.17
The assay of endogenous cholecystokinin and factors influencing its release in the dog and cat. Gastroenterology (1971) 1.17
Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action. FASEB J (2001) 1.16
Mechanism of action of aspirin-like drugs. Semin Arthritis Rheum (1997) 1.16
Role of lipocortin-1 in the anti-hyperalgesic actions of dexamethasone. Br J Pharmacol (1997) 1.15
Identification of several species of phospholipase inhibitory protein(s) by radioimmunoassay for lipomodulin. Biochem Biophys Res Commun (1982) 1.15
Detection of lipocortin 1 in human lung lavage fluid: lipocortin degradation as a possible proteolytic mechanism in the control of inflammatory mediators and inflammation. Environ Health Perspect (1990) 1.14
IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein. Cytokine (1998) 1.14
Measurement of lipocortin 1 levels in murine peripheral blood leukocytes by flow cytometry: modulation by glucocorticoids and inflammation. Br J Pharmacol (1996) 1.11
Lipocortin-1 and the control of arachidonic acid release in cell signalling. Glucocorticoids (changed from glucorticoids) inhibit G protein-dependent activation of cPLA2 activity. Biochem Pharmacol (1995) 1.10
Extraction and thin-layer chromatography of arachidonic acid metabolites. Methods Enzymol (1982) 1.10
Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. J Immunol (1997) 1.09
Lipocortin 1 and the control of cPLA2 activity in A549 cells. Glucocorticoids block EGF stimulation of cPLA2 phosphorylation. Biochem Pharmacol (1996) 1.08
Further characterization of the glucocorticoid-induced antiphospholipase protein "renocortin". Biochem Biophys Res Commun (1983) 1.08
Neutrophil accumulation induced by bacterial lipopolysaccharide: effects of dexamethasone and annexin 1. Clin Exp Immunol (2001) 1.07
Factors influencing the turnover of prostaglandin synthetase. Br J Pharmacol (1975) 1.07
Molecular determinants of monosodium urate crystal-induced murine peritonitis: a role for endogenous mast cells and a distinct requirement for endothelial-derived selectins. J Pharmacol Exp Ther (1997) 1.05
The concerted regulation of cPLA2, COX2, and lipocortin 1 expression by IL-1beta in A549 cells. Biochem Biophys Res Commun (1996) 1.05
Proceedings: Effects of steriod hormones on tissue levels of prostaglandin 15-hydroxydehydrogenase in the rat. Br J Pharmacol (1976) 1.04
Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. Gut (1999) 1.04
21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties. Br J Pharmacol (2000) 1.04
Background and discovery of lipocortins. Agents Actions (1986) 1.04
Prostacyclin is produced in whole blood [proceedings]. Br J Pharmacol (1978) 1.03
Antipyretic actions of human recombinant lipocortin-1. Br J Pharmacol (1991) 1.03
A better understanding of anti-inflammatory drugs based on isoforms of cyclooxygenase (COX-1 and COX-2). Adv Prostaglandin Thromboxane Leukot Res (1995) 1.02
Lipocortin 1: a second messenger of glucocorticoid action in the hypothalamo-pituitary-adrenocortical axis. Mol Med Today (1997) 1.02
Lipocortins (annexins) 1, 2, 4 and 5 are increased in the central nervous system in multiple sclerosis. J Neuroimmunol (1992) 1.02
A role for endogenous histamine in interleukin-8-induced neutrophil infiltration into mouse air-pouch: investigation of the modulatory action of systemic and local dexamethasone. Br J Pharmacol (1994) 1.01
Proceedings: Possible contribution of prostaglandins to genetic hypertension in rats: identification of biochemical lesion. Br J Pharmacol (1975) 1.01
Reversal of the anti-inflammatory effects of dexamethasone by the glucocorticoid antagonist RU 38486. Biochem Pharmacol (1988) 1.00
An immunocytochemical and in situ hybridization analysis of annexin 1 expression in rat mast cells: modulation by inflammation and dexamethasone. Lab Invest (2000) 1.00
Lipocortin 1 reduces myocardial ischemia-reperfusion injury by affecting local leukocyte recruitment. FASEB J (2000) 1.00
Some characteristics of the prostaglandin synthesizing system in rabbit kidney microsomes. Biochim Biophys Acta (1975) 0.98
Modulation of cellular annexin I in human leukocytes infiltrating DTH skin reactions. J Leukoc Biol (1999) 0.97
Functional importance of the dihydropyridine-sensitive, yet voltage-insensitive store-operated Ca2+ influx of U937 cells. FEBS Lett (1996) 0.97
The annexin-1 knockout mouse: what it tells us about the inflammatory response. J Physiol Pharmacol (2002) 0.97