Published in Eur J Pharm Sci on January 21, 2011
Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides. Eur J Pharm Sci (2003) 1.21
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories. Eur J Pharm Sci (2008) 1.16
Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit. AAPS J (2010) 1.11
Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis. Pharm Res (2013) 1.10
The preparation of agglomerates containing solid dispersions of diazepam by melt agglomeration in a high shear mixer. Int J Pharm (2003) 1.09
A new process control strategy for aqueous film coating of pellets in fluidised bed. Eur J Pharm Sci (2003) 1.03
Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic. Adv Drug Deliv Rev (2009) 1.02
Bioavailability of seocalcitol II: development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides. Eur J Pharm Sci (2006) 0.99
In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media. Eur J Pharm Sci (2005) 0.99
Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides. J Pharm Sci (2005) 0.99
Process development for spray drying of sticky pharmaceuticals; case study of bioadhesive nicotine microparticles for compressed medicated chewing gum. Int J Pharm (2013) 0.96
Lipid-based formulations for oral administration of poorly water-soluble drugs. Int J Pharm (2013) 0.95
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. Eur J Pharm Biopharm (2008) 0.92
Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug. Eur J Pharm Sci (2005) 0.91
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. J Pharm Sci (2012) 0.91
Development and evaluation of an ELISA for human trefoil factor 3. Clin Chem (2002) 0.90
In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems. Int J Pharm (2011) 0.89
Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: in vivo bioavailability and dynamic in vitro lipolysis. Pharm Res (2008) 0.88
MAPK and PI3K/AKT mediated YB-1 activation promotes melanoma cell proliferation which is counteracted by an autoregulatory loop. Exp Dermatol (2012) 0.88
Porous magnesium aluminometasilicate tablets as carrier of a cyclosporine self-emulsifying formulation. AAPS PharmSciTech (2009) 0.88
Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: effects on physicochemical properties. Eur J Pharm Biopharm (2008) 0.87
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. J Pharm Sci (2007) 0.87
In vivo human buccal permeability of nicotine. Int J Pharm (2006) 0.86
Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats. Pharm Res (2004) 0.85
Supersaturated self-nanoemulsifying drug delivery systems (Super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs. AAPS J (2012) 0.85
Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation. Eur J Pharm Sci (2012) 0.85
Impact of processing on the taurine content in processed seafood and their corresponding unprocessed raw materials. Int J Food Sci Nutr (2009) 0.85
Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate. J Pharm Sci (2010) 0.85
Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies. J Pharm Pharmacol (2010) 0.84
Influence of bile on the absorption of halofantrine from lipid-based formulations. Eur J Pharm Biopharm (2012) 0.83
Influence of lipid composition and drug load on the In Vitro performance of self-nanoemulsifying drug delivery systems. J Pharm Sci (2012) 0.83
Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats. Pharm Res (2002) 0.83
Nanoporous magnesium aluminometasilicate tablets for precise, controlled, and continuous dosing of chemical reagents and catalysts: applications in parallel solution-phase synthesis. J Comb Chem (2007) 0.82
Bile salts and their importance for drug absorption. Int J Pharm (2013) 0.82
Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80. Eur J Pharm Sci (2008) 0.82
Phase transformations of amlodipine besylate solid forms. J Pharm Sci (2011) 0.82
Enzymatic characterization of lipid-based drug delivery systems. Int J Pharm (2005) 0.81
Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products. Pharm Res (2008) 0.81
Characterising lipid lipolysis and its implication in lipid-based formulation development. AAPS J (2012) 0.81
New lidocaine lozenge as topical anesthesia compared to lidocaine viscous oral solution before upper gastrointestinal endoscopy. Local Reg Anesth (2012) 0.81
Effects of droplet size and type of binder on the agglomerate growth mechanisms by melt agglomeration in a fluidised bed. Eur J Pharm Sci (2002) 0.81
Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound. Eur J Pharm Biopharm (2007) 0.81
Transfusion rate and prevalence of unexpected red blood cell alloantibodies in women undergoing hysterectomy for benign disease. Acta Obstet Gynecol Scand (2011) 0.80
The biopharmaceutics risk assessment roadmap for optimizing clinical drug product performance. J Pharm Sci (2014) 0.80
Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity. J Pharm Sci (2010) 0.80
Feasibility of capsule endoscopy for direct imaging of drug delivery systems in the fasted upper-gastrointestinal tract. Pharm Res (2014) 0.80
Functional characterization of serotonin receptor subtypes in human duodenal secretion. Basic Clin Pharmacol Toxicol (2006) 0.80
Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement. Int J Pharm (2013) 0.80
Bioavailability of seocalcitol III. Administration of lipid-based formulations to minipigs in the fasted and fed state. Eur J Pharm Sci (2007) 0.80
In vitro lipolysis data does not adequately predict the in vivo performance of lipid-based drug delivery systems containing fenofibrate. AAPS J (2014) 0.80
Solid lipid particles for oral delivery of peptide and protein drugs II--the digestion of trilaurin protects desmopressin from proteolytic degradation. Pharm Res (2014) 0.80
Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin. AAPS J (2014) 0.79
IVIVC for fenofibrate immediate release tablets using solubility and permeability as in vitro predictors for pharmacokinetics. J Pharm Sci (2010) 0.79
Oral delivery of peptides and proteins using lipid-based drug delivery systems. Expert Opin Drug Deliv (2012) 0.79
Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol. J Pharm Sci (2006) 0.79
Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium. Eur J Pharm Sci (2013) 0.79
Enhancement of human adaptive immune responses by administration of a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis. J Med Food (2008) 0.79
Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities. Eur J Pharm Biopharm (2013) 0.78
Characterization of spray dried bioadhesive metformin microparticles for oromucosal administration. Eur J Pharm Biopharm (2013) 0.78
The influence of needle size on pain perception in patients treated with botulinum toxin A injections for axillary hyperhidrosis. Acta Derm Venereol (2011) 0.78
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levels. AAPS J (2014) 0.78
Process characteristics and compaction of spray-dried emulsions containing a drug dissolved in lipid. Int J Pharm (2004) 0.78
Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology. Drug Dev Ind Pharm (2012) 0.78
Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. Int J Pharm (2012) 0.78
In vitro investigations of α-amylase mediated hydrolysis of cyclodextrins in the presence of ibuprofen, flurbiprofen, or benzo[a]pyrene. Carbohydr Res (2012) 0.77
Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture. J Pharm Sci (2006) 0.77
Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats. J Pharm Pharmacol (2011) 0.77
Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats. Eur J Pharm Biopharm (2013) 0.77
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS). AAPS J (2016) 0.77
SNEDDS Containing Poorly Water Soluble Cinnarizine; Development and in Vitro Characterization of Dispersion, Digestion and Solubilization. Pharmaceutics (2012) 0.76
Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats. Pharm Res (2006) 0.76
Buccal absorption of propofol when dosed in 1-perfluorobutylpentane to anaesthetised and conscious Wistar rats and Göttingen mini-pigs. Eur J Pharm Biopharm (2013) 0.76
Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy. Mol Pharm (2011) 0.76
pH-triggered drug release from biodegradable microwells for oral drug delivery. Biomed Microdevices (2015) 0.75
In vivo evaluation of tablets and capsules containing spray-dried o/w-emulsions for oral delivery of poorly soluble drugs. Int J Pharm (2005) 0.75
Validation of an image analysis method for estimating coating thickness on pellets. Eur J Pharm Sci (2003) 0.75
Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa. J Pharm Sci (2014) 0.75
Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems. J Pharm Sci (2013) 0.75
Investigation of the intra- and inter-laboratory reproducibility of a small scale standardized supersaturation and precipitation method. Mol Pharm (2017) 0.75
Tablets of functionalized polystyrene beads alone and in combination with solid reagents or catalysts. Preparation and applications in parallel solution and solid phase synthesis. J Comb Chem (2003) 0.75
Azone® decreases the buccal mucosal permeation of diazepam in a concentration-dependent manner via a reservoir effect. J Pharm Sci (2014) 0.75
In vitro, ex vivo and in vivo examination of buccal absorption of metoprolol with varying pH in TR146 cell culture, porcine buccal mucosa and Göttingen minipigs. Eur J Pharm Sci (2013) 0.75
In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems. J Pharm Pharmacol (2014) 0.75
Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques. J Pharm Sci (2014) 0.75
[Adverse effects to transfusion with red donor blood cells are frequent]. Ugeskr Laeger (2014) 0.75
Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms. Eur J Pharm Sci (2007) 0.75
Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans. J Pharm Sci (2014) 0.75
Multivariate toxicity screening of liposomal formulations on a human buccal cell line. Int J Pharm (2006) 0.75
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour. Drug Deliv Transl Res (2014) 0.75
Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection. J Pharm Biomed Anal (2007) 0.75
Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats. J Pharm Pharmacol (2010) 0.75
Development of an ex vivo retention model simulating bioadhesion in the oral cavity using human saliva and physiologically relevant irrigation media. Int J Pharm (2013) 0.75
Toward the establishment of standardized in vitro tests for lipid-based formulations. 5. Lipolysis of representative formulations by gastric lipase. Pharm Res (2014) 0.75