Published in Expert Opin Drug Deliv on August 17, 2012
Peptide design for antimicrobial and immunomodulatory applications. Biopolymers (2013) 0.99
Promises and pitfalls of intracellular delivery of proteins. Bioconjug Chem (2014) 0.95
Long-term delivery of protein therapeutics. Expert Opin Drug Deliv (2014) 0.91
GHK and DNA: resetting the human genome to health. Biomed Res Int (2014) 0.77
Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds. J Control Release (2011) 1.39
Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides. Eur J Pharm Sci (2003) 1.21
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories. Eur J Pharm Sci (2008) 1.16
Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit. AAPS J (2010) 1.11
Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis. Pharm Res (2013) 1.10
Bioavailability of seocalcitol II: development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides. Eur J Pharm Sci (2006) 0.99
In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media. Eur J Pharm Sci (2005) 0.99
Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides. J Pharm Sci (2005) 0.99
Preparation and characterization of poly(DL-lactide-co-glycolide) nanoparticles for siRNA delivery. Int J Pharm (2009) 0.97
Immunity by formulation design: induction of high CD8+ T-cell responses by poly(I:C) incorporated into the CAF01 adjuvant via a double emulsion method. J Control Release (2010) 0.96
Lipid-based formulations for oral administration of poorly water-soluble drugs. Int J Pharm (2013) 0.95
High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization. Eur J Pharm Biopharm (2010) 0.94
Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure. Biochim Biophys Acta (2012) 0.94
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. Eur J Pharm Biopharm (2008) 0.92
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. J Pharm Sci (2012) 0.91
Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug. Eur J Pharm Sci (2005) 0.91
Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. J Control Release (2009) 0.91
Trehalose preserves DDA/TDB liposomes and their adjuvant effect during freeze-drying. Biochim Biophys Acta (2007) 0.89
In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems. Int J Pharm (2011) 0.89
In vitro placental model optimization for nanoparticle transport studies. Int J Nanomedicine (2012) 0.88
Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: in vivo bioavailability and dynamic in vitro lipolysis. Pharm Res (2008) 0.88
Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: effects on physicochemical properties. Eur J Pharm Biopharm (2008) 0.87
Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. J Control Release (2011) 0.87
alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying. Biochim Biophys Acta (2008) 0.87
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. J Pharm Sci (2007) 0.87
Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats. Pharm Res (2004) 0.85
Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate. J Pharm Sci (2010) 0.85
Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation. Eur J Pharm Sci (2012) 0.85
Incorporation of the TLR4 agonist monophosphoryl lipid A into the bilayer of DDA/TDB liposomes: physico-chemical characterization and induction of CD8+ T-cell responses in vivo. Pharm Res (2010) 0.85
Supersaturated self-nanoemulsifying drug delivery systems (Super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs. AAPS J (2012) 0.85
Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo. Eur J Pharm Biopharm (2010) 0.85
Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies. J Pharm Pharmacol (2010) 0.84
Influence of lipid composition and drug load on the In Vitro performance of self-nanoemulsifying drug delivery systems. J Pharm Sci (2012) 0.83
Influence of bile on the absorption of halofantrine from lipid-based formulations. Eur J Pharm Biopharm (2012) 0.83
The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium. Pharm Res (2002) 0.83
Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats. Pharm Res (2002) 0.83
Phase transformations of amlodipine besylate solid forms. J Pharm Sci (2011) 0.82
Bile salts and their importance for drug absorption. Int J Pharm (2013) 0.82
Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80. Eur J Pharm Sci (2008) 0.82
Characterising lipid lipolysis and its implication in lipid-based formulation development. AAPS J (2012) 0.81
Enzymatic characterization of lipid-based drug delivery systems. Int J Pharm (2005) 0.81
Mucus as a barrier to drug delivery – understanding and mimicking the barrier properties. Basic Clin Pharmacol Toxicol (2014) 0.81
Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products. Pharm Res (2008) 0.81
Engineering of an inhalable DDA/TDB liposomal adjuvant: a quality-by-design approach towards optimization of the spray drying process. Pharm Res (2013) 0.81
Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound. Eur J Pharm Biopharm (2007) 0.81
Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity. J Pharm Sci (2010) 0.80
The biopharmaceutics risk assessment roadmap for optimizing clinical drug product performance. J Pharm Sci (2014) 0.80
Feasibility of capsule endoscopy for direct imaging of drug delivery systems in the fasted upper-gastrointestinal tract. Pharm Res (2014) 0.80
Bioavailability of seocalcitol III. Administration of lipid-based formulations to minipigs in the fasted and fed state. Eur J Pharm Sci (2007) 0.80
In vitro lipolysis data does not adequately predict the in vivo performance of lipid-based drug delivery systems containing fenofibrate. AAPS J (2014) 0.80
Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement. Int J Pharm (2013) 0.80
Solid lipid particles for oral delivery of peptide and protein drugs II--the digestion of trilaurin protects desmopressin from proteolytic degradation. Pharm Res (2014) 0.80
Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin. AAPS J (2014) 0.79
Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs. Eur J Pharm Biopharm (2013) 0.79
Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium. Eur J Pharm Sci (2013) 0.79
Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol. J Pharm Sci (2006) 0.79
Stabilization of liposomes during drying. Expert Opin Drug Deliv (2011) 0.79
Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli. J Med Chem (2014) 0.79
CAF01 liposomes as a mucosal vaccine adjuvant: In vitro and in vivo investigations. Int J Pharm (2009) 0.79
Investigation of the interaction between modified ISCOMs and stratum corneum lipid model systems. Biochim Biophys Acta (2010) 0.78
In vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum. AAPS J (2009) 0.78
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levels. AAPS J (2014) 0.78
Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities. Eur J Pharm Biopharm (2013) 0.78
Characterization of spray dried bioadhesive metformin microparticles for oromucosal administration. Eur J Pharm Biopharm (2013) 0.78
Solid-phase route to Fmoc-protected cationic amino acid building blocks. Amino Acids (2012) 0.78
Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. Int J Pharm (2012) 0.78
Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology. Drug Dev Ind Pharm (2012) 0.78
NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01. Eur J Pharm Biopharm (2008) 0.77
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS). AAPS J (2016) 0.77
Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture. J Pharm Sci (2006) 0.77
Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation. AAPS J (2015) 0.77
Designing CAF-adjuvanted dry powder vaccines: spray drying preserves the adjuvant activity of CAF01. J Control Release (2013) 0.77
Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats. Eur J Pharm Biopharm (2013) 0.77
Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats. J Pharm Pharmacol (2011) 0.77
Three-dimensional printing of drug-eluting implants: preparation of an antimicrobial polylactide feedstock material. J Pharm Sci (2015) 0.76
Structure of immune stimulating complex matrices and immune stimulating complexes in suspension determined by small-angle x-ray scattering. Biophys J (2012) 0.76
Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy. Mol Pharm (2011) 0.76
SNEDDS Containing Poorly Water Soluble Cinnarizine; Development and in Vitro Characterization of Dispersion, Digestion and Solubilization. Pharmaceutics (2012) 0.76
Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats. Pharm Res (2006) 0.76
pH-triggered drug release from biodegradable microwells for oral drug delivery. Biomed Microdevices (2015) 0.75
Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems. J Pharm Sci (2013) 0.75
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system. J Pharm Sci (2014) 0.75
Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa. J Pharm Sci (2014) 0.75
Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs. Curr Pharm Des (2015) 0.75
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour. Drug Deliv Transl Res (2014) 0.75
Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution. Int J Pharm (2013) 0.75
Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery In Vitro. Methods Mol Biol (2015) 0.75
Spatial confinement can lead to increased stability of amorphous indomethacin. Eur J Pharm Biopharm (2012) 0.75
Evaluation of carrier-mediated siRNA delivery: lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA. J Control Release (2013) 0.75
Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate. Toxicol In Vitro (2004) 0.75
A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs. Eur J Pharm Sci (2011) 0.75
Miniaturized approach for excipient selection during the development of oral solid dosage form. J Pharm Sci (2014) 0.75
Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful. Eur J Pharm Sci (2012) 0.75
In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems. J Pharm Pharmacol (2014) 0.75
Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans. J Pharm Sci (2014) 0.75
Azone® decreases the buccal mucosal permeation of diazepam in a concentration-dependent manner via a reservoir effect. J Pharm Sci (2014) 0.75
Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms. Eur J Pharm Sci (2007) 0.75