Published in Int J Pharm on August 19, 2012
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Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. J Clin Invest (2002) 1.90
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Quality of generic medicines in South Africa: perceptions versus reality - a qualitative study. BMC Health Serv Res (2012) 1.24
Chitosan-magnesium aluminum silicate composite dispersions: characterization of rheology, flocculate size and zeta potential. Int J Pharm (2007) 1.24
A theoretical and spectroscopic study of gamma-crystalline and amorphous indometacin. J Pharm Pharmacol (2007) 1.22
Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides. Eur J Pharm Sci (2003) 1.21
Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I. Genomics (2002) 1.18
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories. Eur J Pharm Sci (2008) 1.16
Modulation of p-glycoprotein transport function at the blood-brain barrier. Exp Biol Med (Maywood) (2005) 1.16
Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit. AAPS J (2010) 1.11
Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis. Pharm Res (2013) 1.10
The use of quantum chemistry in pharmaceutical research as illustrated by case studies of indometacin and carbamazepine. J Pharm Pharmacol (2007) 1.06
Analysis of coating structures and interfaces in solid oral dosage forms by three dimensional terahertz pulsed imaging. J Pharm Sci (2007) 1.04
Liposomal delivery of antigen to human dendritic cells. Vaccine (2003) 1.04
Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity. J Pharm Sci (2005) 1.02
Characterization of microemulsion structures in the pseudoternary phase diagram of isopropyl palmitate/water/Brij 97:1-butanol. AAPS PharmSciTech (2006) 1.01
Choroid plexus epithelial monolayers--a cell culture model from porcine brain. Cerebrospinal Fluid Res (2006) 1.01
Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR. J Pharmacol Exp Ther (2009) 1.01
Emerging trends in the stabilization of amorphous drugs. Int J Pharm (2012) 1.00
Bioavailability of seocalcitol II: development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides. Eur J Pharm Sci (2006) 0.99
In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media. Eur J Pharm Sci (2005) 0.99
Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides. J Pharm Sci (2005) 0.99
Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs. J Control Release (2008) 0.96
Lipid based particulate formulations for the delivery of antigen. Immunol Cell Biol (2005) 0.95
Lipid-based formulations for oral administration of poorly water-soluble drugs. Int J Pharm (2013) 0.95
The influence of thermal and mechanical preparative techniques on the amorphous state of four poorly soluble compounds. J Pharm Sci (2005) 0.94
Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions. J Pharm Pharm Sci (2007) 0.94
Effects of film coating thickness and drug layer uniformity on in vitro drug release from sustained-release coated pellets: a case study using terahertz pulsed imaging. Int J Pharm (2009) 0.94
Thermal degradation of amorphous glibenclamide. Eur J Pharm Biopharm (2011) 0.94
Characterization of temperature-induced phase transitions in five polymorphic forms of sulfathiazole by terahertz pulsed spectroscopy and differential scanning calorimetry. J Pharm Sci (2006) 0.94
Dry hybrid lipid-silica microcapsules engineered from submicron lipid droplets and nanoparticles as a novel delivery system for poorly soluble drugs. Mol Pharm (2009) 0.93
Dose-related effects of lauric acid on antropyloroduodenal motility, gastrointestinal hormone release, appetite, and energy intake in healthy men. Am J Physiol Regul Integr Comp Physiol (2005) 0.92
Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus. Biochim Biophys Acta (2010) 0.92
Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries. Br J Pharmacol (2003) 0.92
Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. Eur J Pharm Biopharm (2008) 0.92
Comparative effects of intraduodenal infusions of lauric and oleic acids on antropyloroduodenal motility, plasma cholecystokinin and peptide YY, appetite, and energy intake in healthy men. Am J Clin Nutr (2008) 0.91
Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug. Eur J Pharm Sci (2005) 0.91
Applications of terahertz pulsed imaging to sustained-release tablet film coating quality assessment and dissolution performance. J Control Release (2008) 0.91
Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy. Int J Pharm (2006) 0.91
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. J Pharm Sci (2012) 0.91
An overview of recent studies on the analysis of pharmaceutical polymorphs. J Pharm Biomed Anal (2010) 0.91
Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa. Planta Med (2007) 0.91
Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats. Drug Metab Dispos (2008) 0.90
Surveillance of siRNA integrity by FRET imaging. Nucleic Acids Res (2007) 0.90
Preparation of glass solutions of three poorly water soluble drugs by spray drying, melt extrusion and ball milling. Int J Pharm (2006) 0.90
Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: characterisation and in vitro skin penetration. J Pharm Pharmacol (2012) 0.90
Screening for differences in the amorphous state of indomethacin using multivariate visualization. Eur J Pharm Sci (2006) 0.89
In vivo evaluation of chitosan as an adjuvant in subcutaneous vaccine formulations. Vaccine (2013) 0.89
Uptake of apolipoprotein E fragment coupled liposomes by cultured brain microvessel endothelial cells and intact brain capillaries. J Drug Target (2009) 0.89
In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems. Int J Pharm (2011) 0.89
On the preparation, microscopic investigation and application of ISCOMs. Micron (2006) 0.89
Delivery of nanoparticles to the brain detected by fluorescence microscopy. Eur J Pharm Biopharm (2008) 0.88
Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: in vivo bioavailability and dynamic in vitro lipolysis. Pharm Res (2008) 0.88
Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery. Eur J Pharm Biopharm (2010) 0.88
Development and characterisation of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. Int J Pharm (2011) 0.88
The influence of various excipients on the conversion kinetics of carbamazepine polymorphs in aqueous suspension. J Pharm Pharmacol (2007) 0.87
Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: effects on physicochemical properties. Eur J Pharm Biopharm (2008) 0.87
In vitro models to evaluate the permeability of poorly soluble drug entities: challenges and perspectives. Eur J Pharm Sci (2011) 0.87
Modelling the expected net benefits of interventions to reduce the burden of medication errors. J Health Serv Res Policy (2008) 0.87
Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. J Pharm Sci (2007) 0.87
By-passing of P-glycoprotein using immunoliposomes. J Drug Target (2002) 0.87
Drug hydrate systems and dehydration processes studied by terahertz pulsed spectroscopy. Int J Pharm (2006) 0.86
Recent pharmaceutical applications of Raman and terahertz spectroscopies. J Pharm Sci (2008) 0.86
Correlating thermodynamic and kinetic parameters with amorphous stability. Eur J Pharm Sci (2009) 0.86
In vitro and in vivo investigation of thermosensitive chitosan hydrogels containing silica nanoparticles for vaccine delivery. Eur J Pharm Sci (2010) 0.86
Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats. Pharm Res (2004) 0.85
Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation. Eur J Pharm Sci (2012) 0.85
Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells. J Pharm Pharmacol (2006) 0.85
Supersaturated self-nanoemulsifying drug delivery systems (Super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs. AAPS J (2012) 0.85
Influence of polymorphic form, morphology, and excipient interactions on the dissolution of carbamazepine compacts. J Pharm Sci (2007) 0.85
Terahertz pulsed imaging as an analytical tool for sustained-release tablet film coating. Eur J Pharm Biopharm (2008) 0.85
Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate. J Pharm Sci (2010) 0.85
Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: true supersaturation vs. apparent solubility enhancement. Int J Pharm (2012) 0.85
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs. J Pharm Pharmacol (2010) 0.85
Quantitative analysis of polymorphic mixtures of ranitidine hydrochloride by Raman spectroscopy and principal components analysis. Eur J Pharm Biopharm (2002) 0.85
In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins. Fitoterapia (2012) 0.85
The ABC of the blood-brain barrier - regulation of drug efflux pumps. Curr Pharm Des (2011) 0.84
Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule. J Pharmacol Exp Ther (2002) 0.84
Analysis of matrix dosage forms during dissolution testing using raman microscopy. J Pharm Sci (2011) 0.84
Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies. J Pharm Pharmacol (2010) 0.84
Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine. Cancer Genomics Proteomics (2010) 0.84
Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy. Am J Physiol Renal Physiol (2004) 0.84
Analysis of solid-state transformations of pharmaceutical compounds using vibrational spectroscopy. J Pharm Pharmacol (2009) 0.83
Influence of bile on the absorption of halofantrine from lipid-based formulations. Eur J Pharm Biopharm (2012) 0.83
Localization microscopy (SPDM) reveals clustered formations of P-glycoprotein in a human blood-brain barrier model. PLoS One (2012) 0.83
Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2. Eur J Pharm Sci (2008) 0.83
Influence of particle size and preparation methods on the physical and chemical stability of amorphous simvastatin. Eur J Pharm Biopharm (2008) 0.83
Influence of lipid composition and drug load on the In Vitro performance of self-nanoemulsifying drug delivery systems. J Pharm Sci (2012) 0.83