Published in Cell Mol Life Sci on February 03, 2011
Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell (2012) 3.80
Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science (2013) 3.45
Pioneer transcription factors target partial DNA motifs on nucleosomes to initiate reprogramming. Cell (2015) 2.06
DNA methylation presents distinct binding sites for human transcription factors. Elife (2013) 1.63
Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing. Mol Cell Biol (2013) 1.18
The roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generation. Genome Biol (2012) 1.00
Evolving insights on how cytosine methylation affects protein-DNA binding. Brief Funct Genomics (2014) 0.90
Structural basis for Klf4 recognition of methylated DNA. Nucleic Acids Res (2014) 0.89
Novel insight into KLF4 proteolytic regulation in estrogen receptor signaling and breast carcinogenesis. J Biol Chem (2012) 0.86
New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. J Biol Chem (2013) 0.85
Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation. PLoS One (2014) 0.82
miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias. Mol Cancer (2014) 0.80
A new family of predicted Krüppel-like factor genes and pseudogenes in placental mammals. PLoS One (2013) 0.80
Structure solution of DNA-binding proteins and complexes with ARCIMBOLDO libraries. Acta Crystallogr D Biol Crystallogr (2014) 0.79
Induced pluripotent stem cells generated from human adipose-derived stem cells using a non-viral polycistronic plasmid in feeder-free conditions. PLoS One (2012) 0.78
Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis. Nat Commun (2015) 0.78
Molecular basis for modulation of the p53 target selectivity by KLF4. PLoS One (2012) 0.78
KLF/SP Transcription Factor Family Evolution: Expansion, Diversification, and Innovation in Eukaryotes. Genome Biol Evol (2015) 0.78
KLF4 translation level is associated with differentiation stage of different pediatric leukemias in both cell lines and primary samples. Clin Exp Med (2012) 0.77
Krüppel-like Factor 4 Blocks Hepatocellular Carcinoma Dedifferentiation and Progression through Activation of Hepatocyte Nuclear Factor-6. Clin Cancer Res (2015) 0.77
Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells. J Biol Chem (2016) 0.75
The human nucleophosmin 1 mutation A inhibits myeloid differentiation of leukemia cells by modulating miR-10b. Oncotarget (2016) 0.75
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability. Nucleic Acids Res (2017) 0.75
Sp5 induces the expression of Nanog to maintain mouse embryonic stem cell self-renewal. PLoS One (2017) 0.75
Protein production and purification. Nat Methods (2008) 3.97
Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin. J Synchrotron Radiat (2012) 2.43
Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition. J Biol Chem (2002) 1.92
Vectors for co-expression of an unrestricted number of proteins. Nucleic Acids Res (2007) 1.85
Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations. Genes Dev (2011) 1.69
A binuclear manganese cluster that catalyzes radical-mediated N-oxygenation. Angew Chem Int Ed Engl (2007) 1.69
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy. Nature (2013) 1.66
Usa1 functions as a scaffold of the HRD-ubiquitin ligase. Mol Cell (2009) 1.58
The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria. Proc Natl Acad Sci U S A (2009) 1.48
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Circ Cardiovasc Genet (2012) 1.48
The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition. Nucleic Acids Res (2003) 1.45
Hematopoietic stem cell transplantation without irradiation. Nat Methods (2009) 1.27
Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E). Blood (2004) 1.26
Sequence-specific DNA binding determined by contacts outside the helix-turn-helix motif of the ParB homolog KorB. Nat Struct Mol Biol (2004) 1.21
Structure of the extracellular portion of CD46 provides insights into its interactions with complement proteins and pathogens. PLoS Pathog (2010) 1.20
An intersubunit active site between supercoiled parallel beta helices in the trimeric tailspike endorhamnosidase of Shigella flexneri Phage Sf6. Structure (2008) 1.18
Building functional modules from molecular interactions. Trends Biochem Sci (2006) 1.17
Crystal structure of Escherichia coli phage HK620 tailspike: podoviral tailspike endoglycosidase modules are evolutionarily related. Mol Microbiol (2008) 1.16
Structural genomics of human proteins--target selection and generation of a public catalogue of expression clones. Microb Cell Fact (2005) 1.15
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization. EMBO J (2005) 1.11
The Lin28 cold-shock domain remodels pre-let-7 microRNA. Nucleic Acids Res (2012) 1.10
Vinylogous chain branching catalysed by a dedicated polyketide synthase module. Nature (2013) 1.09
T-rich DNA single strands bind to a preformed site on the bacterial cold shock protein Bs-CspB. J Mol Biol (2006) 1.08
The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex. EMBO Rep (2005) 1.08
Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2. J Mol Biol (2006) 1.06
Crystal structure of Homo sapiens protein hp14.5. Proteins (2004) 1.05
Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity. J Am Chem Soc (2010) 1.05
Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR. J Biomol NMR (2005) 1.02
HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. J Mol Cell Biol (2012) 1.02
An Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4. J Biol Chem (2001) 1.01
The coxsackievirus-adenovirus receptor reveals complex homophilic and heterophilic interactions on neural cells. J Neurosci (2010) 1.00
Mechanisms of Lin28-mediated miRNA and mRNA regulation--a structural and functional perspective. Int J Mol Sci (2013) 1.00
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880. Biol Chem (2004) 1.00
Tail morphology controls DNA release in two Salmonella phages with one lipopolysaccharide receptor recognition system. Mol Microbiol (2012) 1.00
Bidirectional binding of invariant chain peptides to an MHC class II molecule. Proc Natl Acad Sci U S A (2010) 0.99
Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins. Genes Dev (2010) 0.98
Structural basis of the interaction of MbtH-like proteins, putative regulators of nonribosomal peptide biosynthesis, with adenylating enzymes. J Biol Chem (2012) 0.97
In vitro reconstitution of a cellular phase-transition process that involves the mRNA decapping machinery. Angew Chem Int Ed Engl (2014) 0.97
IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development. J Immunol (2008) 0.96
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation. EMBO J (2011) 0.95
RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution. RNA (2011) 0.94
Structural basis for the substrate specificity of a Bacillus 1,3-1,4-beta-glucanase. J Mol Biol (2006) 0.94
High resolution crystal structure of domain I of the Saccharomyces cerevisiae homing endonuclease PI-SceI. Nucleic Acids Res (2002) 0.94
Iron-sulfur cluster N7 of the NADH:ubiquinone oxidoreductase (complex I) is essential for stability but not involved in electron transfer. Biochemistry (2007) 0.93
Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19. J Biol Chem (2010) 0.92
Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells. FEBS Lett (2008) 0.92
Optimized variants of the cold shock protein from in vitro selection: structural basis of their high thermostability. J Mol Biol (2007) 0.92
Crystal structure of NblA from Anabaena sp. PCC 7120, a small protein playing a key role in phycobilisome degradation. J Biol Chem (2005) 0.91
Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1. Biochemistry (2004) 0.91
Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias. Blood (2009) 0.91
Unique self-palmitoylation activity of the transport protein particle component Bet3: a mechanism required for protein stability. Proc Natl Acad Sci U S A (2006) 0.91
X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma. Proteins (2004) 0.90
Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands. PLoS Pathog (2010) 0.89
Unusual armadillo fold in the human general vesicular transport factor p115. PLoS One (2009) 0.89
Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation. RNA Biol (2013) 0.88
Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN. FEBS Lett (2002) 0.88
Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme. FEBS J (2010) 0.88
Sequence specificity of single-stranded DNA-binding proteins: a novel DNA microarray approach. Nucleic Acids Res (2007) 0.87
Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study. J Struct Biol (2011) 0.87
Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease. J Mol Med (Berl) (2008) 0.86
Structural proteomics: from the molecule to the system. Nat Struct Mol Biol (2007) 0.84
X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1). BMC Struct Biol (2005) 0.84
Structure and catalytic mechanism of a cyclic dipeptide prenyltransferase with broad substrate promiscuity. J Mol Biol (2012) 0.84
An approach to quality management in structural biology: biophysical selection of proteins for successful crystallization. J Struct Biol (2008) 0.84
Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo. ChemMedChem (2015) 0.84
Armadillo motifs involved in vesicular transport. PLoS One (2010) 0.82
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex. J Biol Chem (2012) 0.82
Optimization of the gbeta1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization. J Mol Biol (2007) 0.82
Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain. ChemMedChem (2011) 0.82
A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis. Nat Chem Biol (2011) 0.82
Repression of transcriptional activity of C/EBPalpha by E2F-dimerization partner complexes. Mol Cell Biol (2010) 0.82
Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage. Nucleic Acids Res (2013) 0.81
Loss of Irf8 does not co-operate with overexpression of BCL-2 in the induction of leukemias in vivo. Leuk Lymphoma (2009) 0.81
Crystal structure of KorA bound to operator DNA: insight into repressor cooperation in RP4 gene regulation. Nucleic Acids Res (2009) 0.81
Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags. J Struct Funct Genomics (2003) 0.80
Structural and functional characterization of human Iba proteins. FEBS J (2008) 0.80
The dipole moment of the electron carrier adrenodoxin is not critical for redox partner interaction and electron transfer. J Inorg Biochem (2009) 0.79
The interaction domain of the redox protein adrenodoxin is mandatory for binding of the electron acceptor CYP11A1, but is not required for binding of the electron donor adrenodoxin reductase. Biochem Biophys Res Commun (2005) 0.79
An essential serotype recognition pocket on phage P22 tailspike protein forces Salmonella enterica serovar Paratyphi A O-antigen fragments to bind as nonsolution conformers. Glycobiology (2013) 0.79
Modeling of electrostatic recognition processes in the mammalian mitochondrial steroid hydroxylase system. Biophys Chem (2003) 0.78
Single amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinity. Glycobiology (2012) 0.78
Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex. J Mol Biol (2012) 0.78
High-resolution crystal structures of Caldicellulosiruptor strain Rt8B.4 carbohydrate-binding module CBM27-1 and its complex with mannohexaose. J Mol Biol (2004) 0.78
PAN-modular structure of microneme protein SML-2 from the parasite Sarcocystis muris at 1.95 Å resolution and its complex with 1-thio-β-D-galactose. Acta Crystallogr D Biol Crystallogr (2011) 0.78
Structure of circularly permuted DsbA(Q100T99): preserved global fold and local structural adjustments. Acta Crystallogr D Biol Crystallogr (2004) 0.78
Single-stranded DNA bound to bacterial cold-shock proteins: preliminary crystallographic and Raman analysis. Acta Crystallogr D Biol Crystallogr (2004) 0.77
Structural and phylogenetic analyses of the GP42 transglutaminase from Phytophthora sojae reveal an evolutionary relationship between oomycetes and marine Vibrio bacteria. J Biol Chem (2011) 0.77
Purification and preliminary X-ray crystallographic studies of beta-microseminoprotein from human seminal plasma. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.77
Dimer formation of a stabilized Gbeta1 variant: a structural and energetic analysis. J Mol Biol (2009) 0.77
Disturbed function of the blood-cerebrospinal fluid barrier aggravates neuro-inflammation. Acta Neuropathol (2013) 0.77
Crystallization and preliminary X-ray analysis of human nicotinamide mononucleotide adenylyltransferase (NMNAT). Acta Crystallogr D Biol Crystallogr (2001) 0.76
Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold. Protein Sci (2006) 0.76
An idea whose time has come. Genome Biol (2007) 0.76
Crystal structure of the yeast TRAPP-associated protein Tca17. FEBS J (2014) 0.76
Characterization of the self-palmitoylation activity of the transport protein particle component Bet3. Cell Mol Life Sci (2010) 0.75
Polymorphism of the alpha4-subunit of VLA-4 integrin and bone marrow transplantation. Haematologica (2004) 0.75
Low-resolution ab initio phasing of Sarcocystis muris lectin SML-2. Acta Crystallogr D Biol Crystallogr (2006) 0.75