Efficient detection of RNA-protein interactions using tethered RNAs.

Natural RNA circles function as efficient microRNA sponges. Nature (2013) 8.93

C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Nature (2014) 3.59

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell (2012) 1.28

Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution. J Am Chem Soc (2014) 1.20

catRAPID omics: a web server for large-scale prediction of protein-RNA interactions. Bioinformatics (2013) 1.13

An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins. Nucleic Acids Res (2013) 1.00

The regulation of trypanosome gene expression by RNA-binding proteins. PLoS Pathog (2013) 0.98

Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus. Genes Dev (2015) 0.97

A Spinach molecular beacon triggered by strand displacement. RNA (2014) 0.96

Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors. Mol Cell (2015) 0.93

Studying protein-protein affinity and immobilized ligand-protein affinity interactions using MS-based methods. Anal Bioanal Chem (2011) 0.88

Co-expression of RNA-protein complexes in Escherichia coli and applications to RNA biology. Nucleic Acids Res (2013) 0.88

Prediction of RNA binding proteins comes of age from low resolution to high resolution. Mol Biosyst (2013) 0.86

Prediction and validation of the unexplored RNA-binding protein atlas of the human proteome. Proteins (2013) 0.86

RNA type III secretion signals that require Hfq. J Bacteriol (2013) 0.82

Identification of RNAIII-binding proteins in Staphylococcus aureus using tethered RNAs and streptavidin aptamers based pull-down assay. BMC Microbiol (2015) 0.79

Advances in methods for native expression and purification of RNA for structural studies. Curr Opin Struct Biol (2014) 0.78

Design, synthesis, and application of Spinach molecular beacons triggered by strand displacement. Methods Enzymol (2015) 0.76

Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases. Nucleic Acids Res (2016) 0.76

Modulation of ccrAB Expression and SCCmec Excision by an Inverted Repeat Element and SarS in Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother (2015) 0.75

Urb-RIP - An Adaptable and Efficient Approach for Immunoprecipitation of RNAs and Associated RNAs/Proteins. PLoS One (2016) 0.75

Generation of Recombinant Polioviruses Harboring RNA Affinity Tags in the 5' and 3' Noncoding Regions of Genomic RNAs. Viruses (2016) 0.75

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79

Functional annotation of a full-length mouse cDNA collection. Nature (2001) 23.61

Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell (2007) 8.43

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell (2001) 6.50

Characterization of a beta-actin mRNA zipcode-binding protein. Mol Cell Biol (1997) 5.21

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proc Natl Acad Sci U S A (2002) 3.14

Recombinant RNA technology: the tRNA scaffold. Nat Methods (2007) 2.73

The importance of being modified: roles of modified nucleosides and Mg2+ in RNA structure and function. Prog Nucleic Acid Res Mol Biol (1996) 2.43

Streptavidin aptamers: affinity tags for the study of RNAs and ribonucleoproteins. RNA (2001) 2.11

Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA. J Biol Chem (1994) 1.49

In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic Acids Res (2009) 1.15

A sequence-specific RNA-binding protein complements apobec-1 To edit apolipoprotein B mRNA. Mol Cell Biol (1998) 1.14

Dynein-mediated apical localization of crumbs transcripts is required for Crumbs activity in epithelial polarity. J Cell Biol (2008) 1.10

Isolation of specific RNA-binding proteins using the streptomycin-binding RNA aptamer. Nat Protoc (2006) 1.07

Purification of functional RNA-protein complexes using MS2-MBP. Curr Protoc Mol Biol (2003) 1.02

RNA affinity tags for the rapid purification and investigation of RNAs and RNA-protein complexes. Methods Mol Biol (2008) 0.96

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev (2003) 17.64

The PAR proteins: fundamental players in animal cell polarization. Dev Cell (2007) 4.92

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol (2002) 4.29

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. Nat Cell Biol (2005) 3.83

Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell (2004) 3.52

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nat Cell Biol (2003) 3.07

Structural insight into filament formation by mammalian septins. Nature (2007) 2.90

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins. J Cell Biol (2002) 2.51

Exportin-5 mediates nuclear export of minihelix-containing RNAs. J Biol Chem (2002) 2.48

A conserved family of enzymes that phosphorylate inositol hexakisphosphate. Science (2007) 2.43

C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats. J Biol Chem (2004) 2.42

Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell (2007) 2.36

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat Cell Biol (2007) 2.36

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. J Cell Biol (2005) 2.28

Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Mol Biol Cell (2006) 2.22

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. RNA (2004) 2.21

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis. Nat Cell Biol (2006) 2.12

Genome-wide screen reveals APC-associated RNAs enriched in cell protrusions. Nature (2008) 1.98

NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. Nature (2010) 1.95

Systems analysis of Ran transport. Science (2002) 1.94

Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. J Clin Invest (2006) 1.92

Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr Biol (2010) 1.86

Assembly of epithelial tight junctions is negatively regulated by Par6. Curr Biol (2002) 1.84

Proteomic identification of the cerebral cavernous malformation signaling complex. J Proteome Res (2007) 1.83

The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis. Genes Dev (2009) 1.82

mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression. Nat Cell Biol (2005) 1.78

The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev Cell (2008) 1.77

Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Mol Biol Cell (2005) 1.75

Borg/septin interactions and the assembly of mammalian septin heterodimers, trimers, and filaments. J Biol Chem (2002) 1.69

Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival. Mol Cell (2008) 1.67

Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell (2012) 1.65

Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6. EMBO J (2003) 1.60

Epithelial organization, cell polarity and tumorigenesis. Trends Cell Biol (2011) 1.59

Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells. Mol Biol Cell (2006) 1.59

Clostridium taeniosporum spore ribbon-like appendage structure, composition and genes. Mol Microbiol (2007) 1.58

Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation. J Cell Biol (2010) 1.58

STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Mol Biol Cell (2008) 1.54

LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Curr Biol (2002) 1.48

Widely conserved signaling pathways in the establishment of cell polarity. Cold Spring Harb Perspect Biol (2009) 1.47

Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J Biol Chem (2004) 1.47

Npap60/Nup50 is a tri-stable switch that stimulates importin-alpha:beta-mediated nuclear protein import. Cell (2002) 1.46

A systems analysis of importin-{alpha}-{beta} mediated nuclear protein import. J Cell Biol (2005) 1.43

ROCK1 phosphorylates and activates zipper-interacting protein kinase. J Biol Chem (2006) 1.40

Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3. J Biol Chem (2003) 1.34

Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import. J Cell Biol (2004) 1.33

Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5. Mol Cell Biol (2004) 1.31

A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25. Mol Biol Cell (2006) 1.31

Posttranslational modification of CENP-A influences the conformation of centromeric chromatin. Proc Natl Acad Sci U S A (2013) 1.30

The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export. J Biol Chem (2004) 1.24

Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1. J Cell Biol (2008) 1.22

Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. J Biol Chem (2002) 1.21

Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. J Cell Biol (2006) 1.17

Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties. Gene (2002) 1.13

Isoforms of the polarity protein par6 have distinct functions. J Biol Chem (2004) 1.12

Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11. Mol Cell Biol (2002) 1.11

Application of chemoproteomics to drug discovery: identification of a clinical candidate targeting hsp90. Chem Biol (2010) 1.09

Structural analysis of septin 2, 6, and 7 complexes. J Biol Chem (2006) 1.08

RNA localization and polarity: from A(PC) to Z(BP). Trends Cell Biol (2009) 1.07

Sustained activation of the HER1-ERK1/2-RSK signaling pathway controls myoepithelial cell fate in human mammary tissue. Genes Dev (2011) 1.07

Substrate specificity of mammalian N-terminal α-amino methyltransferase NRMT. Biochemistry (2012) 1.05

An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets. Mol Cell Proteomics (2008) 1.04

The RNA-binding protein Fus directs translation of localized mRNAs in APC-RNP granules. J Cell Biol (2013) 1.01

The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. J Biol Chem (2011) 0.96

A novel nuclear export signal in Smad1 is essential for its signaling activity. J Biol Chem (2003) 0.95

Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis. Mol Pharmacol (2002) 0.93

Signaling pathways in cell polarity. Cold Spring Harb Perspect Biol (2012) 0.92

The adapter importin-alpha provides flexible control of nuclear import at the expense of efficiency. Mol Syst Biol (2007) 0.92

The kinetochore NUPtials. Nat Cell Biol (2003) 0.90

Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolus. J Cell Sci (2003) 0.90

Fluorescence resonance energy transfer biosensors that detect Ran conformational changes and a Ran x GDP-importin-beta -RanBP1 complex in vitro and in intact cells. J Biol Chem (2002) 0.88

RNA interference techniques to study epithelial cell adhesion and polarity. Methods Enzymol (2006) 0.87

Development and validation of a test battery to assess subtle neurodevelopmental differences in children. Neurotoxicology (2006) 0.87

Smoothelin-like 1 protein regulates myosin phosphatase-targeting subunit 1 expression during sexual development and pregnancy. J Biol Chem (2010) 0.86

The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi. PLoS One (2012) 0.86

NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1. Biochem J (2013) 0.86

Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells. Chem Biol (2013) 0.84

Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy. J Biol Chem (2011) 0.82

Novel biosensors for the detection of estrogen receptor ligands. J Steroid Biochem Mol Biol (2005) 0.82

Characterization of a UBC13 kinase in Plasmodium falciparum. Proc Natl Acad Sci U S A (2007) 0.81

Real-time in vivo proteomic identification of novel kinase substrates in smooth muscle. Methods Mol Biol (2007) 0.77

Detection of RNA-Protein Interactions Using Tethered RNA Affinity Capture. Methods Mol Biol (2015) 0.77

Does FACS perturb gene expression? Cytometry A (2015) 0.76

The use of permeabilized cell systems to study nuclear transport. Methods Mol Biol (2002) 0.76

Phosphoproteome analysis in yeast. Methods Enzymol (2003) 0.76

Depletion of the adaptor protein NCK increases UV-induced p53 phosphorylation and promotes apoptosis. PLoS One (2013) 0.75

Loss of the Par3 Polarity Protein Promotes Breast Tumorigenesis and Metastasis. Cancer Cell (2016) 0.75

Changes in magnetization transfer MRI correlate with spreading depression-induced astroglial reactivity and increased protein expression in mice. AJR Am J Roentgenol (2004) 0.75

Mixed peptide sequencing and the FASTF/FASTS algorithms. Methods Enzymol (2003) 0.75