Published in Proc Natl Acad Sci U S A on February 14, 2011
Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication. Proc Natl Acad Sci U S A (2014) 1.36
Myosin-X: a MyTH-FERM myosin at the tips of filopodia. J Cell Sci (2011) 1.27
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain. EMBO J (2011) 1.08
Structural basis of the myosin X PH1(N)-PH2-PH1(C) tandem as a specific and acute cellular PI(3,4,5)P(3) sensor. Mol Biol Cell (2011) 0.96
Antiparallel coiled-coil-mediated dimerization of myosin X. Proc Natl Acad Sci U S A (2012) 0.96
A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching. J Cell Biol (2014) 0.95
Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds. Dev Cell (2015) 0.93
Myosin-X functions in polarized epithelial cells. Mol Biol Cell (2012) 0.93
Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread. Cell Microbiol (2012) 0.88
Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin. J Biol Chem (2015) 0.86
Signaling mechanism of the netrin-1 receptor DCC in axon guidance. Prog Biophys Mol Biol (2015) 0.85
Structural basis of the binding of Merlin FERM domain to the E3 ubiquitin ligase substrate adaptor DCAF1. J Biol Chem (2014) 0.81
Headless Myo10 is a negative regulator of full-length Myo10 and inhibits axon outgrowth in cortical neurons. J Biol Chem (2012) 0.81
Myosin-X and disease. Exp Cell Res (2015) 0.79
Myosin X and its motorless isoform differentially modulate dendritic spine development by regulating trafficking and retention of vasodilator-stimulated phosphoprotein. J Cell Sci (2013) 0.79
Characterization of a myosin VII MyTH/FERM domain. J Mol Biol (2011) 0.79
Orchestration of microtubules and the actin cytoskeleton in trichome cell shape determination by a plant-unique kinesin. Elife (2015) 0.78
Structural basis of kindlin-mediated integrin recognition and activation. Proc Natl Acad Sci U S A (2017) 0.78
Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc Natl Acad Sci U S A (2016) 0.77
The Intracellular Domain of the Frazzled/DCC Receptor Is a Transcription Factor Required for Commissural Axon Guidance. Neuron (2015) 0.77
MyTH4-FERM myosins have an ancient and conserved role in filopod formation. Proc Natl Acad Sci U S A (2016) 0.77
A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip. J Biol Chem (2016) 0.77
Myosin-10 independently influences mitotic spindle structure and mitotic progression. Cytoskeleton (Hoboken) (2016) 0.76
p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance. J Biol Chem (2015) 0.76
The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions. Front Endocrinol (Lausanne) (2017) 0.75
MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions. Curr Opin Cell Biol (2016) 0.75
Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proc Natl Acad Sci U S A (2017) 0.75
Protein structure comparison by alignment of distance matrices. J Mol Biol (1993) 34.74
Filopodia: molecular architecture and cellular functions. Nat Rev Mol Cell Biol (2008) 6.40
Structural basis of integrin activation by talin. Cell (2007) 5.37
Structural determinants of integrin recognition by talin. Mol Cell (2003) 4.20
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell (2000) 3.94
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J (2002) 3.53
A microtubule-binding myosin required for nuclear anchoring and spindle assembly. Nature (2004) 2.89
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner. EMBO J (2007) 2.73
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility. Nat Cell Biol (2002) 2.59
Myosin-X provides a motor-based link between integrins and the cytoskeleton. Nat Cell Biol (2004) 2.58
Myosin-X is a molecular motor that functions in filopodia formation. Proc Natl Acad Sci U S A (2006) 2.36
Interactions in the network of Usher syndrome type 1 proteins. Hum Mol Genet (2004) 2.16
Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly. Hum Mol Genet (2004) 2.04
Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex. EMBO J (2003) 1.70
Myosin-X: a molecular motor at the cell's fingertips. Trends Cell Biol (2005) 1.61
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation. J Cell Biol (2007) 1.61
Myosin X regulates netrin receptors and functions in axonal path-finding. Nat Cell Biol (2007) 1.55
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors. J Cell Biol (2007) 1.54
Structural basis for NHERF recognition by ERM proteins. Structure (2006) 1.41
Evaluation of the myosin VIIA gene and visual function in patients with Usher syndrome type I. Exp Eye Res (2000) 1.31
FERM proteins in animal morphogenesis. Curr Opin Genet Dev (2009) 1.27
Structural basis for CD44 recognition by ERM proteins. J Biol Chem (2008) 1.26
Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids. Hum Mol Genet (2010) 1.14
Myosin-X induces filopodia by multiple elongation mechanism. J Biol Chem (2010) 1.10
Identification and molecular modelling of a mutation in the motor head domain of myosin VIIA in a family with autosomal dominant hearing impairment (DFNA11). Hum Genet (2004) 1.07
Mutation profile of the MYO7A gene in Spanish patients with Usher syndrome type I. Hum Mutat (2006) 1.07
Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain. J Mol Biol (2008) 1.06
Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions. J Cell Sci (2007) 1.05
Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex. J Biol Chem (2007) 1.05
Structural basis of PSGL-1 binding to ERM proteins. Genes Cells (2007) 1.04
Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins. J Mol Biol (2008) 1.01
Myosin-X is required for cranial neural crest cell migration in Xenopus laevis. Dev Dyn (2009) 0.97
Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase. Structure (2010) 0.95
Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells. Dev Biol (2009) 0.94
A novel calcium/calmodulin-regulated kinesin-like protein is highly conserved between monocots and dicots. DNA Cell Biol (2000) 0.87
Vertebrate MAX-1 is required for vascular patterning in zebrafish. Proc Natl Acad Sci U S A (2006) 0.86
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev (2011) 3.15
Choosing an optimal method to combine P-values. Stat Med (2009) 3.15
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol (2009) 2.84
Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol (2010) 2.80
The clinical value of diffusion-weighted imaging in combination with T2-weighted imaging in diagnosing prostate carcinoma: a systematic review and meta-analysis. AJR Am J Roentgenol (2012) 2.51
Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity. J Neurosci (2006) 2.34
Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density. Nat Rev Neurosci (2009) 2.22
Estrogen receptor inhibits mineralocorticoid receptor transcriptional regulatory function. Endocrinology (2014) 2.17
Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. J Mol Biol (2007) 2.08
Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency. Blood (2002) 1.96
The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase. Mol Cell (2010) 1.90
Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury. Circulation (2012) 1.78
PDZ domains of Par-3 as potential phosphoinositide signaling integrators. Mol Cell (2007) 1.70
A long noncoding RNA regulates photoperiod-sensitive male sterility, an essential component of hybrid rice. Proc Natl Acad Sci U S A (2012) 1.59
A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses. J Neurosci (2004) 1.53
Myosin VI undergoes cargo-mediated dimerization. Cell (2009) 1.47
Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG. Nat Commun (2012) 1.46
Application of ICHD-II criteria in a headache clinic of China. PLoS One (2012) 1.46
Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95. J Mol Biol (2003) 1.45
Candidate-gene association study of mothers with pre-eclampsia, and their infants, analyzing 775 SNPs in 190 genes. Hum Hered (2006) 1.41
Left ventricular apical aneurysm associated with normal coronary arteries following cardiac surgery: echocardiographic features and differential diagnosis. Int J Cardiol (2013) 1.39
Effects of active and passive smoking on the development of cardiovascular disease as assessed by a carotid intima-media thickness examination in patients with type 2 diabetes mellitus. Clin Exp Pharmacol Physiol (2015) 1.38
The 8-kDa dynein light chain binds to p53-binding protein 1 and mediates DNA damage-induced p53 nuclear accumulation. J Biol Chem (2004) 1.37
Regional homogeneity in depression and its relationship with separate depressive symptom clusters: a resting-state fMRI study. J Affect Disord (2008) 1.35
HISTONE DEACETYLASE6 interacts with FLOWERING LOCUS D and regulates flowering in Arabidopsis. Plant Physiol (2011) 1.30
Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment. J Biol Chem (2008) 1.29
Hexaaqua-manganese(II) dipicrate dihydrate. Acta Crystallogr Sect E Struct Rep Online (2008) 1.29
LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways. Mol Cell (2011) 1.28
Anatomic and functional evaluation of the lymphatics and lymph nodes in diagnosis of lymphatic circulation disorders with contrast magnetic resonance lymphangiography. J Vasc Surg (2009) 1.25
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol (2011) 1.24
Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures. Biochem J (2013) 1.23
Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes. EMBO J (2007) 1.20
Endophilin B1 as a novel regulator of nerve growth factor/ TrkA trafficking and neurite outgrowth. J Neurosci (2008) 1.20
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules. EMBO J (2011) 1.19
Pseudoaneurysm of the mitral-aortic intervalvular fibrosa. Int J Cardiol (2012) 1.19
The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins. Proc Natl Acad Sci U S A (2010) 1.18
Binding of hsp90-associated immunophilins to cytoplasmic dynein: direct binding and in vivo evidence that the peptidylprolyl isomerase domain is a dynein interaction domain. Biochemistry (2002) 1.18
Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites. EMBO J (2008) 1.18
Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo. Science (2011) 1.17
Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor. Mol Cell (2009) 1.17
Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23. Proc Natl Acad Sci U S A (2009) 1.16
A randomized control trial on interruption of HBV transmission in uterus. Chin Med J (Engl) (2003) 1.15
Cytokeratin 10 and cytokeratin 19: predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection. Clin Cancer Res (2008) 1.13
The Arabidopsis BRAHMA chromatin-remodeling ATPase is involved in repression of seed maturation genes in leaves. Plant Physiol (2008) 1.13
Detecting genetic interactions for quantitative traits with U-statistics. Genet Epidemiol (2011) 1.13
Chaperone-mediated autophagy degrades mutant p53. Genes Dev (2013) 1.11
The tetrameric L27 domain complex as an organization platform for supramolecular assemblies. Nat Struct Mol Biol (2004) 1.10
The Par3/Par6/aPKC complex and epithelial cell polarity. Exp Cell Res (2013) 1.10
HD2C interacts with HDA6 and is involved in ABA and salt stress response in Arabidopsis. J Exp Bot (2012) 1.09
Hydrogen sulphide regulates calcium homeostasis in microglial cells. Glia (2006) 1.09
Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice. J Pharmacol Exp Ther (2010) 1.08
A regularized regression approach for dissecting genetic conflicts that increase disease risk in pregnancy. Stat Appl Genet Mol Biol (2009) 1.07
Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem. Nat Struct Mol Biol (2005) 1.07
Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses. Infect Immun (2006) 1.06
Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding. Nat Struct Biol (2003) 1.04
p150(Glued), Dynein, and microtubules are specifically required for activation of MKK3/6 and p38 MAPKs. J Biol Chem (2004) 1.03
Pharmacology and signaling properties of epidermal growth factor receptor isoforms studied by bioluminescence resonance energy transfer. Mol Pharmacol (2006) 1.03
PKCdelta regulates endothelial basal barrier function through modulation of RhoA GTPase activity. Exp Cell Res (2005) 1.03
Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin. EMBO J (2005) 1.03
MicroRNA regulation of STAT4 protein expression: rapid and sensitive modulation of IL-12 signaling in human natural killer cells. Blood (2011) 1.03
Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life. Cell Mol Life Sci (2014) 1.03
Comparative study of the anatomy, CT and MR images of the lateral collateral ligaments of the ankle joint. Surg Radiol Anat (2008) 1.02
Extensions of PDZ domains as important structural and functional elements. Protein Cell (2010) 1.02
Gene expression in archived newborn blood spots distinguishes infants who will later develop cerebral palsy from matched controls. Pediatr Res (2012) 1.02
Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures. Mol Cell (2011) 1.02
Real-time 3-dimensional echocardiography in assessing atrial and ventricular septal defects: an echocardiographic-surgical correlative study. Am Heart J (2004) 1.01
MiR-139 targets CXCR4 and inhibits the proliferation and metastasis of laryngeal squamous carcinoma cells. Med Oncol (2013) 1.01
Model for mapping imprinted quantitative trait loci in an inbred F2 design. Genomics (2006) 1.01
Detection in 2009 of the swine origin influenza A (H1N1) virus by a subtyping microarray. J Clin Microbiol (2009) 1.00
The affected-/discordant-sib-pair design can guarantee validity of multipoint model-free linkage analysis of incomplete pedigrees when there is marker-marker disequilibrium. Am J Hum Genet (2006) 1.00
JIP3 mediates TrkB axonal anterograde transport and enhances BDNF signaling by directly bridging TrkB with kinesin-1. J Neurosci (2011) 0.99
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis. Mol Biol Cell (2003) 0.99
Cutaneous angiosarcoma of the head and neck: a case presentation and review of the literature. Ear Nose Throat J (2006) 0.99
NMR structure of a type IVb pilin from Salmonella typhi and its assembly into pilus. J Biol Chem (2004) 0.99
Structures of usher syndrome 1 proteins and their complexes. Physiology (Bethesda) (2012) 0.99
The association between breastfeeding and childhood obesity: a meta-analysis. BMC Public Health (2014) 0.99
High-density lipoprotein increases the abundance of eNOS protein in human vascular endothelial cells by increasing its half-life. J Am Coll Cardiol (2003) 0.98
Identification of the yeast R-SNARE Nyv1p as a novel longin domain-containing protein. Mol Biol Cell (2006) 0.98
Methylation signature of lymph node metastases in breast cancer patients. BMC Cancer (2012) 0.98
Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration. EMBO J (2011) 0.98
Modeling extent and distribution of zygotic disequilibrium: implications for a multigenerational canine pedigree. Genetics (2006) 0.97
Serine 88 phosphorylation of the 8-kDa dynein light chain 1 is a molecular switch for its dimerization status and functions. J Biol Chem (2007) 0.97
Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice. J Cell Biol (2007) 0.97
Nummular headache: peripheral or central? One case with reappearance of nummular headache after focal scalp was removed, and literature review. Cephalalgia (2013) 0.96
A non-parametric method for building predictive genetic tests on high-dimensional data. Hum Hered (2011) 0.96
Structural basis of the myosin X PH1(N)-PH2-PH1(C) tandem as a specific and acute cellular PI(3,4,5)P(3) sensor. Mol Biol Cell (2011) 0.96
Antiparallel coiled-coil-mediated dimerization of myosin X. Proc Natl Acad Sci U S A (2012) 0.96
The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye. Cell (2011) 0.96
Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics. J Biol Chem (2003) 0.95
Therapeutic effect of forest bathing on human hypertension in the elderly. J Cardiol (2012) 0.95
Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase. Structure (2010) 0.95
Angiogenic biomarkers for prediction of maternal and neonatal complications in suspected preeclampsia. J Matern Fetal Neonatal Med (2012) 0.95
Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation. Arterioscler Thromb Vasc Biol (2013) 0.95