Published in Psychopharmacology (Berl) on February 18, 2011
A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence. J Addict Med (2013) 1.47
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Varenicline decreases nicotine self-administration and cue-induced reinstatement of nicotine-seeking behaviour in rats when a long pretreatment time is used. Int J Neuropsychopharmacol (2011) 1.06
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Effect of fenfluramine on reinstatement of food seeking in female and male rats: implications for the predictive validity of the reinstatement model. Psychopharmacology (Berl) (2011) 0.98
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Varenicline effects on drinking, craving and neural reward processing among non-treatment-seeking alcohol-dependent individuals. Psychopharmacology (Berl) (2014) 0.85
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The effects of varenicline on attention and inhibitory control among treatment-seeking smokers. Psychopharmacology (Berl) (2012) 0.81
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Effects of chronic varenicline treatment on nicotine, cocaine, and concurrent nicotine+cocaine self-administration. Neuropsychopharmacology (2013) 0.78
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Varenicline Reduces Context-Induced Relapse to Alcohol-Seeking through Actions in the Nucleus Accumbens. Neuropsychopharmacology (2016) 0.77
Effects of varenicline on operant self-administration of alcohol and/or nicotine in a rat model of co-abuse. Behav Brain Res (2015) 0.77
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Varenicline and cytisine: two nicotinic acetylcholine receptor ligands reduce ethanol intake in University of Chile bibulous rats. Psychopharmacology (Berl) (2013) 0.77
Effect of Varenicline Combined with High-Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings. Alcohol Clin Exp Res (2016) 0.76
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The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in male rats. Behav Brain Res (2016) 0.75
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Sex differences in attenuation of nicotine reinstatement after individual and combined treatments of progesterone and varenicline. Behav Brain Res (2016) 0.75
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Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats. Alcohol Clin Exp Res (2017) 0.75
The α3β4 nAChR partial agonist AT-1001 attenuates stress-induced reinstatement of nicotine seeking in a rat model of relapse and induces minimal withdrawal in dependent rats. Behav Brain Res (2017) 0.75
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Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Mol Pharmacol (2006) 3.84
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Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking. Proc Natl Acad Sci U S A (2007) 2.68
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Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats. Biol Psychiatry (2007) 2.37
Varenicline improves mood and cognition during smoking abstinence. Biol Psychiatry (2008) 2.29
Varenicline reduces alcohol self-administration in heavy-drinking smokers. Biol Psychiatry (2009) 2.25
Cognitive enhancement as a pharmacotherapy target for stimulant addiction. Addiction (2010) 2.04
Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats. Neuropsychopharmacology (2010) 1.99
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Amphetamine impairs the discriminative performance of rats with dorsal noradrenergic bundle lesions on a 5-choice serial reaction time task: new evidence for central dopaminergic-noradrenergic interactions. Psychopharmacology (Berl) (1987) 1.45
Involvement of dopamine D1 and D2 receptors in the nucleus accumbens core and shell in inhibitory response control. Psychopharmacology (Berl) (2006) 1.41
Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition. Biochem Pharmacol (2009) 1.37
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Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats. Psychopharmacology (Berl) (2005) 1.35
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Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice. Psychopharmacology (Berl) (2009) 1.26
The smoking cessation medication varenicline attenuates alcohol and nicotine interactions in the rat mesolimbic dopamine system. J Pharmacol Exp Ther (2009) 1.25
The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats. Psychopharmacology (Berl) (2009) 1.24
Dopaminergic mechanisms mediating the incentive to seek cocaine and heroin following long-term withdrawal of IV drug self-administration. Psychopharmacology (Berl) (1999) 1.22
Nicotinic acetylcholine receptors in the ventral tegmental area mediate the dopamine activating and reinforcing properties of ethanol cues. Psychopharmacology (Berl) (2007) 1.22
Is an alpha-conotoxin MII-sensitive mechanism involved in the neurochemical, stimulatory, and rewarding effects of ethanol? Alcohol (2005) 1.17
Role of the subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of ethanol. Alcohol Alcohol (2006) 1.17
Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance. Trends Pharmacol Sci (2005) 1.16
Characterisation of the effects of nicotine in the five-choice serial reaction time task in rats: antagonist studies. Psychopharmacology (Berl) (2000) 1.09
Nicotine enhances sustained attention in the rat under specific task conditions. Psychopharmacology (Berl) (1998) 1.08
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Smoking cessation efficacy and safety of varenicline, an alpha4beta2 nicotinic receptor partial agonist. J Cardiovasc Nurs (2007) 0.87
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Varenicline ameliorates ethanol-induced deficits in learning in C57BL/6 mice. Neurobiol Learn Mem (2008) 0.83
Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats. Biol Psychiatry (2007) 2.37
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking. Nat Neurosci (2008) 1.98
Critical involvement of dopaminergic neurotransmission in impulsive decision making. Biol Psychiatry (2005) 1.80
Neuroadaptive effects of active versus passive drug administration in addiction research. Trends Pharmacol Sci (2003) 1.47
Cannabinoid CB1 receptors control conditioned drug seeking. Trends Pharmacol Sci (2005) 1.45
Involvement of dopamine D1 and D2 receptors in the nucleus accumbens core and shell in inhibitory response control. Psychopharmacology (Berl) (2006) 1.41
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The relationship between impulsive choice and impulsive action: a cross-species translational study. PLoS One (2012) 1.33
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Psychostimulant-induced behavioral sensitization depends on nicotinic receptor activation. J Neurosci (2002) 1.30
Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats. Neuropsychopharmacology (2008) 1.26
Methylphenidate disrupts social play behavior in adolescent rats. Neuropsychopharmacology (2008) 1.25
Cannabinoid modulation of the reinforcing and motivational properties of heroin and heroin-associated cues in rats. Psychopharmacology (Berl) (2003) 1.24
Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization. Neuropsychopharmacology (2002) 1.23
Prefrontal cortex plasticity mechanisms in drug seeking and relapse. Neurosci Biobehav Rev (2009) 1.23
Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking. Neuropsychopharmacology (2010) 1.17
Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence. Nat Neurosci (2011) 1.16
Inhibitory control and response latency differences between C57BL/6J and DBA/2J mice in a Go/No-Go and 5-choice serial reaction time task and strain-specific responsivity to amphetamine. Behav Brain Res (2010) 1.14
Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum. Neuron (2012) 1.13
Acute effects of morphine on distinct forms of impulsive behavior in rats. Psychopharmacology (Berl) (2009) 1.13
Stress-induced hyperthermia and anxiety: pharmacological validation. Eur J Pharmacol (2003) 1.13
Trait impulsive choice predicts resistance to extinction and propensity to relapse to cocaine seeking: a bidirectional investigation. Neuropsychopharmacology (2012) 1.11
Cholinergic modulation of nucleus accumbens medium spiny neurons. Eur J Neurosci (2002) 1.10
Beta-adrenoceptor mediated inhibition of long-term reward-related memory reconsolidation. Behav Brain Res (2006) 1.09
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci (2007) 1.08
The role of CB1 receptors in psychostimulant addiction. Addict Biol (2008) 1.07
Pharmacological manipulation of memory reconsolidation: towards a novel treatment of pathogenic memories. Eur J Pharmacol (2008) 1.07
Cannabinoid modulation of executive functions. Eur J Pharmacol (2008) 1.06
Effects of the cannabinoid CB1 receptor antagonist rimonabant on distinct measures of impulsive behavior in rats. Psychopharmacology (Berl) (2007) 1.04
Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats. Psychopharmacology (Berl) (2007) 1.03
Enhanced cortical and accumbal molecular reactivity associated with conditioned heroin, but not sucrose-seeking behaviour. J Neurochem (2006) 1.02
Suppression of conditioned nicotine and sucrose seeking by the cannabinoid-1 receptor antagonist SR141716A. Behav Brain Res (2005) 1.02
Dopamine receptor D1/D5 gene expression in the medial prefrontal cortex predicts impulsive choice in rats. Cereb Cortex (2009) 1.02
Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli. Behav Neurosci (2009) 0.99
Disruption of Long-Term Alcohol-Related Memory Reconsolidation: Role of β-Adrenoceptors and NMDA Receptors. Front Behav Neurosci (2010) 0.98
μ-Opioid receptors in the nucleus accumbens shell region mediate the effects of amphetamine on inhibitory control but not impulsive choice. J Neurosci (2011) 0.97
Poor impulse control predicts inelastic demand for nicotine but not alcohol in rats. Addict Biol (2011) 0.96
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization. Psychopharmacology (Berl) (2003) 0.96
Targeting cocaine versus heroin memories: divergent roles within ventromedial prefrontal cortex. Trends Pharmacol Sci (2013) 0.95
Cannabinoid CB1 receptor activation mediates the opposing effects of amphetamine on impulsive action and impulsive choice. PLoS One (2011) 0.95
Insulin modulates cocaine-sensitive monoamine transporter function and impulsive behavior. J Neurosci (2011) 0.94
Enhanced motivation to self-administer cocaine is predicted by self-grooming behaviour and relates to dopamine release in the rat medial prefrontal cortex and amygdala. Eur J Neurosci (2002) 0.94
Morphine exposure and abstinence define specific stages of gene expression in the rat nucleus accumbens. FASEB J (2004) 0.93
Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats. Psychopharmacology (Berl) (2008) 0.93
Unidirectional relationship between heroin self-administration and impulsive decision-making in rats. Psychopharmacology (Berl) (2011) 0.93
Active heroin administration induces specific genomic responses in the nucleus accumbens shell. FASEB J (2002) 0.92
Differential involvement of the prelimbic cortex and striatum in conditioned heroin and sucrose seeking following long-term extinction. Eur J Neurosci (2005) 0.89
Intermittent administration of morphine alters protein expression in rat nucleus accumbens. Proteomics (2006) 0.89
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5-HT1A receptor knockout mice and mice overexpressing corticotropin-releasing hormone in models of anxiety. Eur J Pharmacol (2003) 0.88
Long-term gene expression in the nucleus accumbens following heroin administration is subregion-specific and depends on the nature of drug administration. Addict Biol (2005) 0.87
Compartment-specific changes in striatal neuronal activity during expression of amphetamine sensitization are the result of drug hypersensitivity. Eur J Neurosci (2002) 0.87
Increased impulsivity in rats as a result of repeated cycles of alcohol intoxication and abstinence. Addict Biol (2013) 0.86
Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study. ACS Chem Neurosci (2012) 0.86
Reduced dopamine transporter binding predates impulse control disorders in Parkinson's disease. Mov Disord (2014) 0.85
Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat. PLoS One (2011) 0.85