Published in Trends Pharmacol Sci on August 01, 2005
The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev (2006) 6.80
Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addict Biol (2008) 1.72
The endocannabinoid system in brain reward processes. Br J Pharmacol (2008) 1.71
The neuropharmacology of relapse to food seeking: methodology, main findings, and comparison with relapse to drug seeking. Prog Neurobiol (2009) 1.48
Shared brain vulnerabilities open the way for nonsubstance addictions: carving addiction at a new joint? Ann N Y Acad Sci (2010) 1.46
Endocannabinoids promote cocaine-induced impulsivity and its rapid dopaminergic correlates. Biol Psychiatry (2013) 1.44
The future of endocannabinoid-oriented clinical research after CB1 antagonists. Psychopharmacology (Berl) (2009) 1.42
The incentive salience of alcohol: translating the effects of genetic variant in CNR1. Arch Gen Psychiatry (2008) 1.36
Inhibition of fatty acid amide hydrolase reduces reinstatement of nicotine seeking but not break point for nicotine self-administration--comparison with CB(1) receptor blockade. Psychopharmacology (Berl) (2009) 1.19
Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery? Br J Pharmacol (2010) 1.19
Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies. Addict Biol (2008) 1.15
Blockade of THC-seeking behavior and relapse in monkeys by the cannabinoid CB(1)-receptor antagonist rimonabant. Neuropsychopharmacology (2008) 1.15
Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system. Neurosci Biobehav Rev (2010) 1.15
Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum. Neuron (2012) 1.13
Peptide YY3-36 decreases reinstatement of high-fat food seeking during dieting in a rat relapse model. J Neurosci (2007) 1.10
Adenosine A2A receptors in ventral striatum, hypothalamus and nociceptive circuitry implications for drug addiction, sleep and pain. Prog Neurobiol (2007) 1.10
Endocannabinoid system involvement in brain reward processes related to drug abuse. Pharmacol Res (2007) 1.07
Endocannabinoid signalling in reward and addiction. Nat Rev Neurosci (2015) 1.04
Effects of the cannabinoid CB1 receptor antagonist rimonabant on distinct measures of impulsive behavior in rats. Psychopharmacology (Berl) (2007) 1.04
The CB1 antagonist rimonabant (SR141716) blocks cue-induced reinstatement of cocaine seeking and other context and extinction phenomena predictive of relapse. Drug Alcohol Depend (2009) 1.03
Cannabinoid receptor 1 gene association with nicotine dependence. Arch Gen Psychiatry (2008) 1.01
A brain on cannabinoids: the role of dopamine release in reward seeking. Cold Spring Harb Perspect Med (2012) 1.00
Disruption of Long-Term Alcohol-Related Memory Reconsolidation: Role of β-Adrenoceptors and NMDA Receptors. Front Behav Neurosci (2010) 0.98
The selective anandamide transport inhibitor VDM11 attenuates reinstatement of nicotine seeking behaviour, but does not affect nicotine intake. Br J Pharmacol (2011) 0.96
Voluntary exercise and sucrose consumption enhance cannabinoid CB1 receptor sensitivity in the striatum. Neuropsychopharmacology (2010) 0.94
More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology (2009) 0.92
Mechanism-based medication development for the treatment of nicotine dependence. Acta Pharmacol Sin (2009) 0.91
Gene-environment interactions in vulnerability to cocaine intravenous self-administration: a brief social experience affects intake in DBA/2J but not in C57BL/6J mice. Psychopharmacology (Berl) (2007) 0.91
Diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 antagonists. J Med Chem (2012) 0.89
Involvement of the endocannabinoid system in reward processing in the human brain. Psychopharmacology (Berl) (2011) 0.88
Time-dependent induction of CREB phosphorylation in the hippocampus by the endogenous cannabinoid. Neurosci Lett (2009) 0.87
Effects of endocannabinoid neurotransmission modulators on brain stimulation reward. Psychopharmacology (Berl) (2006) 0.86
Differential Control of Cocaine Self-Administration by GABAergic and Glutamatergic CB1 Cannabinoid Receptors. Neuropsychopharmacology (2015) 0.86
Effects of cannabinoid receptor antagonists on maintenance and reinstatement of methamphetamine self-administration in rhesus monkeys. Eur J Pharmacol (2010) 0.85
The endocannabinoid system: a new molecular target for the treatment of tobacco addiction. CNS Neurol Disord Drug Targets (2008) 0.85
Animal models of cannabinoid reward. Br J Pharmacol (2010) 0.84
Endocannabinoid signaling in midbrain dopamine neurons: more than physiology? Curr Neuropharmacol (2007) 0.82
Cortico-limbic circuitry for conditioned nicotine-seeking behavior in rats involves endocannabinoid signaling. Psychopharmacology (Berl) (2007) 0.81
Drug addiction. Curr Top Behav Neurosci (2009) 0.81
Gender-stratified gene and gene-treatment interactions in smoking cessation. Pharmacogenomics J (2011) 0.81
Differential involvement of the endocannabinoid system in short- and long-term expression of incentive learning supported by nicotine in rats. Psychopharmacology (Berl) (2006) 0.80
Sensitization to cocaine is inhibited after intra-accumbal GR103691 or rimonabant, but it is enhanced after co-infusion indicating functional interaction between accumbens D(3) and CB1 receptors. Psychopharmacology (Berl) (2010) 0.80
Effects of cannabinoid CB1 receptor antagonist rimonabant in consolidation and reconsolidation of methamphetamine reward memory in mice. Psychopharmacology (Berl) (2009) 0.80
Differential effect of opioid and cannabinoid receptor blockade on heroin-seeking reinstatement and cannabinoid substitution in heroin-abstinent rats. Br J Pharmacol (2011) 0.80
Weight gain, schizophrenia and antipsychotics: new findings from animal model and pharmacogenomic studies. Schizophr Res Treatment (2010) 0.79
THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction. Transl Psychiatry (2013) 0.79
Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach. Prog Neuropsychopharmacol Biol Psychiatry (2013) 0.79
Diet-induced changes in n-3- and n-6-derived endocannabinoids and reductions in headache pain and psychological distress. J Pain (2015) 0.79
Preclinical Studies of Cannabinoid Reward, Treatments for Cannabis Use Disorder, and Addiction-Related Effects of Cannabinoid Exposure. Neuropsychopharmacology (2017) 0.78
Rimonabant blocks the expression but not the development of locomotor sensitization to nicotine in rats. Psychopharmacology (Berl) (2007) 0.78
Role of endocannabinoids in regulating drug dependence. Neuropsychiatr Dis Treat (2007) 0.78
Pyrazole antagonists of the CB1 receptor with reduced brain penetration. Bioorg Med Chem (2016) 0.78
Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Humans. PLoS One (2013) 0.78
Blockade of Nicotine and Cannabinoid Reinforcement and Relapse by a Cannabinoid CB1-Receptor Neutral Antagonist AM4113 and Inverse Agonist Rimonabant in Squirrel Monkeys. Neuropsychopharmacology (2016) 0.78
Medial prefrontal cannabinoid CB1 receptors modulate consolidation and extinction of cocaine-associated memory in mice. Psychopharmacology (Berl) (2014) 0.77
Endocannabinoids underlie reconsolidation of hedonic memories in Wistar rats. Psychopharmacology (Berl) (2013) 0.77
To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making. Front Behav Neurosci (2015) 0.76
Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex. Int J Neuropsychopharmacol (2014) 0.76
Tales from the dark side: do neuromodulators of drug withdrawal require changes in endocannabinoid tone? Prog Neuropsychopharmacol Biol Psychiatry (2013) 0.76
Local pretreatment with the cannabinoid CB1 receptor antagonist AM251 attenuates methamphetamine intra-accumbens self-administration. Neurosci Lett (2010) 0.76
Paradoxical effects of the endocannabinoid uptake inhibitor VDM11 on accumbal neural encoding of reward predictive cues. Synapse (2012) 0.76
A Highly Polymorphic Copy Number Variant in the NSF Gene is Associated with Cocaine Dependence. Sci Rep (2016) 0.75
Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): development of ligands with optimized lipophilicity and binding affinity. Eur J Med Chem (2008) 0.75
Screening Medications for the Treatment of Cannabis Use Disorder. Int Rev Neurobiol (2016) 0.75
The CB1 Neutral Antagonist AM4113 Retains the Therapeutic Efficacy of the Inverse Agonist Rimonabant for Nicotine Dependence and Weight Loss with Better Psychiatric Tolerability. Int J Neuropsychopharmacol (2016) 0.75
Association Study of Two Cannabinoid Receptor Genes, CNR1 and CNR2, with Methamphetamine Dependence. Curr Neuropharmacol (2011) 0.75
Inhibition of monoacylglycerol lipase (MAGL) enhances cue-induced reinstatement of nicotine-seeking behavior in mice. Psychopharmacology (Berl) (2015) 0.75
Intra-accumbal Cannabinoid Agonist Attenuated Reinstatement but not Extinction Period of Morphine-Induced Conditioned Place Preference; Evidence for Different Characteristics of Extinction Period and Reinstatement. Neurochem Res (2017) 0.75
Impulsive choice and impulsive action predict vulnerability to distinct stages of nicotine seeking in rats. Biol Psychiatry (2007) 2.37
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking. Nat Neurosci (2008) 1.98
Critical involvement of dopaminergic neurotransmission in impulsive decision making. Biol Psychiatry (2005) 1.80
Neuroadaptive effects of active versus passive drug administration in addiction research. Trends Pharmacol Sci (2003) 1.47
Involvement of dopamine D1 and D2 receptors in the nucleus accumbens core and shell in inhibitory response control. Psychopharmacology (Berl) (2006) 1.41
Behavioral disinhibition requires dopamine receptor activation. Psychopharmacology (Berl) (2006) 1.34
The relationship between impulsive choice and impulsive action: a cross-species translational study. PLoS One (2012) 1.33
Varenicline attenuates cue-induced relapse to alcohol, but not nicotine seeking, while reducing inhibitory response control. Psychopharmacology (Berl) (2011) 1.31
Long-lasting cognitive deficits resulting from adolescent nicotine exposure in rats. Neuropsychopharmacology (2008) 1.26
Methylphenidate disrupts social play behavior in adolescent rats. Neuropsychopharmacology (2008) 1.25
Cannabinoid modulation of the reinforcing and motivational properties of heroin and heroin-associated cues in rats. Psychopharmacology (Berl) (2003) 1.24
Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization. Neuropsychopharmacology (2002) 1.23
Extracellular matrix plasticity and GABAergic inhibition of prefrontal cortex pyramidal cells facilitates relapse to heroin seeking. Neuropsychopharmacology (2010) 1.17
Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence. Nat Neurosci (2011) 1.16
Inhibitory control and response latency differences between C57BL/6J and DBA/2J mice in a Go/No-Go and 5-choice serial reaction time task and strain-specific responsivity to amphetamine. Behav Brain Res (2010) 1.14
Acute effects of morphine on distinct forms of impulsive behavior in rats. Psychopharmacology (Berl) (2009) 1.13
Cholinergic modulation of nucleus accumbens medium spiny neurons. Eur J Neurosci (2002) 1.10
Beta-adrenoceptor mediated inhibition of long-term reward-related memory reconsolidation. Behav Brain Res (2006) 1.09
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci (2007) 1.08
The role of CB1 receptors in psychostimulant addiction. Addict Biol (2008) 1.07
Pharmacological manipulation of memory reconsolidation: towards a novel treatment of pathogenic memories. Eur J Pharmacol (2008) 1.07
Cannabinoid modulation of executive functions. Eur J Pharmacol (2008) 1.06
Effects of the cannabinoid CB1 receptor antagonist rimonabant on distinct measures of impulsive behavior in rats. Psychopharmacology (Berl) (2007) 1.04
Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats. Psychopharmacology (Berl) (2007) 1.03
Enhanced cortical and accumbal molecular reactivity associated with conditioned heroin, but not sucrose-seeking behaviour. J Neurochem (2006) 1.02
Suppression of conditioned nicotine and sucrose seeking by the cannabinoid-1 receptor antagonist SR141716A. Behav Brain Res (2005) 1.02
Dopamine receptor D1/D5 gene expression in the medial prefrontal cortex predicts impulsive choice in rats. Cereb Cortex (2009) 1.02
Trait impulsivity predicts escalation of sucrose seeking and hypersensitivity to sucrose-associated stimuli. Behav Neurosci (2009) 0.99
Disruption of Long-Term Alcohol-Related Memory Reconsolidation: Role of β-Adrenoceptors and NMDA Receptors. Front Behav Neurosci (2010) 0.98
μ-Opioid receptors in the nucleus accumbens shell region mediate the effects of amphetamine on inhibitory control but not impulsive choice. J Neurosci (2011) 0.97
On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization. Psychopharmacology (Berl) (2003) 0.96
Poor impulse control predicts inelastic demand for nicotine but not alcohol in rats. Addict Biol (2011) 0.96
Cannabinoid CB1 receptor activation mediates the opposing effects of amphetamine on impulsive action and impulsive choice. PLoS One (2011) 0.95
Enhanced motivation to self-administer cocaine is predicted by self-grooming behaviour and relates to dopamine release in the rat medial prefrontal cortex and amygdala. Eur J Neurosci (2002) 0.94
Morphine exposure and abstinence define specific stages of gene expression in the rat nucleus accumbens. FASEB J (2004) 0.93
Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats. Psychopharmacology (Berl) (2008) 0.93
Unidirectional relationship between heroin self-administration and impulsive decision-making in rats. Psychopharmacology (Berl) (2011) 0.93
Active heroin administration induces specific genomic responses in the nucleus accumbens shell. FASEB J (2002) 0.92
Differential involvement of the prelimbic cortex and striatum in conditioned heroin and sucrose seeking following long-term extinction. Eur J Neurosci (2005) 0.89
Intermittent administration of morphine alters protein expression in rat nucleus accumbens. Proteomics (2006) 0.89
Long-term gene expression in the nucleus accumbens following heroin administration is subregion-specific and depends on the nature of drug administration. Addict Biol (2005) 0.87
Compartment-specific changes in striatal neuronal activity during expression of amphetamine sensitization are the result of drug hypersensitivity. Eur J Neurosci (2002) 0.87
Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study. ACS Chem Neurosci (2012) 0.86
Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat. PLoS One (2011) 0.85
Exocytotic release of creatine in rat brain. Synapse (2006) 0.84
Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex. FASEB J (2012) 0.83
Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms. Psychopharmacology (Berl) (2013) 0.82
Intermittent morphine treatment induces a long-lasting increase in cholinergic modulation of GABAergic synapses in nucleus accumbens of adult rats. Synapse (2005) 0.81
On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists. Psychopharmacology (Berl) (2011) 0.80
Individual differences in sensitivity to factors provoking reinstatement of cocaine-seeking behavior. Behav Brain Res (2004) 0.80
Long-lasting nicotinic modulation of GABAergic synaptic transmission in the rat nucleus accumbens associated with behavioural sensitization to amphetamine. Eur J Neurosci (2004) 0.80
Morphine causes a delayed increase in glutamate receptor functioning in the nucleus accumbens core. Eur J Pharmacol (2005) 0.79
A proteomics approach to identify long-term molecular changes in rat medial prefrontal cortex resulting from sucrose self-administration. J Proteome Res (2006) 0.78
On the Role of Cannabinoid CB1- and μ-Opioid Receptors in Motor Impulsivity. Front Pharmacol (2012) 0.77
5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement. Int J Neuropsychopharmacol (2010) 0.77
Molecular reactivity of mesocorticolimbic brain areas of high and low grooming rats after elevated plus maze exposure. Brain Res Mol Brain Res (2005) 0.77