| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders.
|
Trends Neurosci
|
2004
|
2.76
|
|
2
|
"Control" laboratory rodents are metabolically morbid: why it matters.
|
Proc Natl Acad Sci U S A
|
2010
|
2.50
|
|
3
|
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma.
|
Free Radic Biol Med
|
2006
|
2.32
|
|
4
|
Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice.
|
Exp Neurol
|
2007
|
2.04
|
|
5
|
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
|
Nat Med
|
2011
|
1.97
|
|
6
|
Caloric restriction and intermittent fasting: two potential diets for successful brain aging.
|
Ageing Res Rev
|
2006
|
1.94
|
|
7
|
Modulation of taste sensitivity by GLP-1 signaling.
|
J Neurochem
|
2008
|
1.89
|
|
8
|
Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice.
|
Hippocampus
|
2009
|
1.84
|
|
9
|
A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin.
|
Ageing Res Rev
|
2004
|
1.68
|
|
10
|
Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess.
|
Endocrinology
|
2007
|
1.59
|
|
11
|
The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women.
|
Br J Nutr
|
2013
|
1.56
|
|
12
|
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.
|
Diabetes
|
2008
|
1.42
|
|
13
|
VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis.
|
PLoS One
|
2012
|
1.36
|
|
14
|
Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging.
|
PLoS One
|
2010
|
1.32
|
|
15
|
Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells.
|
Diabetes
|
2011
|
1.26
|
|
16
|
Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice.
|
Neurobiol Aging
|
2008
|
1.22
|
|
17
|
Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
|
Am J Physiol Endocrinol Metab
|
2007
|
1.22
|
|
18
|
Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders.
|
Curr Alzheimer Res
|
2012
|
1.19
|
|
19
|
iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease.
|
PLoS One
|
2008
|
1.16
|
|
20
|
Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression.
|
Diabetes
|
2010
|
1.16
|
|
21
|
Allosteric modulators of g protein-coupled receptors: future therapeutics for complex physiological disorders.
|
J Pharmacol Exp Ther
|
2009
|
1.15
|
|
22
|
Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women.
|
Metabolism
|
2007
|
1.13
|
|
23
|
Modulation of taste sensitivity by GLP-1 signaling in taste buds.
|
Ann N Y Acad Sci
|
2009
|
1.12
|
|
24
|
Elevated prostaglandin EP2 receptor in endometrial adenocarcinoma cells promotes vascular endothelial growth factor expression via cyclic 3',5'-adenosine monophosphate-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase 1/2 signaling pathways.
|
Mol Endocrinol
|
2004
|
1.09
|
|
25
|
VennPlex--a novel Venn diagram program for comparing and visualizing datasets with differentially regulated datapoints.
|
PLoS One
|
2013
|
1.08
|
|
26
|
Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.
|
PLoS One
|
2008
|
1.07
|
|
27
|
Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses.
|
PLoS One
|
2010
|
1.06
|
|
28
|
Cytoskeletal reorganization dependence of signaling by the gonadotropin-releasing hormone receptor.
|
J Biol Chem
|
2003
|
1.04
|
|
29
|
Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity.
|
PLoS One
|
2011
|
1.04
|
|
30
|
Growth factor signals in neural cells: coherent patterns of interaction control multiple levels of molecular and phenotypic responses.
|
J Biol Chem
|
2008
|
1.02
|
|
31
|
Regulation of Caenorhabditis elegans vitellogenesis by DAF-2/IIS through separable transcriptional and posttranscriptional mechanisms.
|
BMC Physiol
|
2011
|
1.02
|
|
32
|
Ghrelin is produced in taste cells and ghrelin receptor null mice show reduced taste responsivity to salty (NaCl) and sour (citric acid) tastants.
|
PLoS One
|
2010
|
1.01
|
|
33
|
Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment.
|
PLoS One
|
2009
|
1.00
|
|
34
|
Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease.
|
Int J Alzheimers Dis
|
2010
|
1.00
|
|
35
|
Therapeutic perspectives for the treatment of Huntington's disease: treating the whole body.
|
Histol Histopathol
|
2008
|
0.99
|
|
36
|
Class II G protein-coupled receptors and their ligands in neuronal function and protection.
|
Neuromolecular Med
|
2005
|
0.99
|
|
37
|
Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults.
|
PLoS One
|
2012
|
0.99
|
|
38
|
Textrous!: extracting semantic textual meaning from gene sets.
|
PLoS One
|
2013
|
0.98
|
|
39
|
Targeting TNF-alpha receptors for neurotherapeutics.
|
Trends Neurosci
|
2008
|
0.97
|
|
40
|
Nuclear stabilization of beta-catenin and inactivation of glycogen synthase kinase-3beta by gonadotropin-releasing hormone: targeting Wnt signaling in the pituitary gonadotrope.
|
Mol Endocrinol
|
2007
|
0.97
|
|
41
|
Hormones in the naso-oropharynx: endocrine modulation of taste and smell.
|
Trends Endocrinol Metab
|
2009
|
0.96
|
|
42
|
The effects of the ketogenic diet on behavior and cognition.
|
Epilepsy Res
|
2011
|
0.96
|
|
43
|
Transferrin fusion technology: a novel approach to prolonging biological half-life of insulinotropic peptides.
|
J Pharmacol Exp Ther
|
2010
|
0.96
|
|
44
|
Growth inhibition by miR-519 via multiple p21-inducing pathways.
|
Mol Cell Biol
|
2012
|
0.95
|
|
45
|
Reduced energy intake: the secret to a long and healthy life?
|
IBS J Sci
|
2007
|
0.93
|
|
46
|
β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo.
|
Mol Endocrinol
|
2013
|
0.93
|
|
47
|
Caloric restriction: impact upon pituitary function and reproduction.
|
Ageing Res Rev
|
2008
|
0.91
|
|
48
|
Mammalian type I gonadotropin-releasing hormone receptors undergo slow, constitutive, agonist-independent internalization.
|
Endocrinology
|
2007
|
0.91
|
|
49
|
Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington disease is related to their physiological efficacy.
|
J Biol Chem
|
2012
|
0.91
|
|
50
|
Gonadotropin-releasing hormone-induced activation of diacylglycerol kinase-zeta and its association with active c-src.
|
J Biol Chem
|
2004
|
0.90
|
|
51
|
Protein twists and turns in Alzheimer disease.
|
Nat Med
|
2006
|
0.90
|
|
52
|
Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes.
|
PLoS One
|
2011
|
0.90
|
|
53
|
Rapid and enhanced proteolytic digestion using electric-field-oriented enzyme reactor.
|
J Proteomics
|
2011
|
0.88
|
|
54
|
Central role of the EGF receptor in neurometabolic aging.
|
Int J Endocrinol
|
2012
|
0.88
|
|
55
|
Effective correction of experimental errors in quantitative proteomics using stable isotope labeling by amino acids in cell culture (SILAC).
|
J Proteomics
|
2012
|
0.87
|
|
56
|
Chemical modification of class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies.
|
Pharmacol Ther
|
2009
|
0.87
|
|
57
|
Age-related changes in mouse taste bud morphology, hormone expression, and taste responsivity.
|
J Gerontol A Biol Sci Med Sci
|
2011
|
0.86
|
|
58
|
Discontinuous pH gradient-mediated separation of TiO2-enriched phosphopeptides.
|
Anal Biochem
|
2010
|
0.86
|
|
59
|
Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms.
|
J Signal Transduct
|
2010
|
0.86
|
|
60
|
Gonadotropin-releasing hormone analog structural determinants of selectivity for inhibition of cell growth: support for the concept of ligand-induced selective signaling.
|
Mol Endocrinol
|
2008
|
0.86
|
|
61
|
Therapeutic targeting of the endoplasmic reticulum in Alzheimer's disease.
|
Curr Alzheimer Res
|
2012
|
0.86
|
|
62
|
Ghrelin receptor signaling: a promising therapeutic target for metabolic syndrome and cognitive dysfunction.
|
CNS Neurol Disord Drug Targets
|
2010
|
0.85
|
|
63
|
GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats.
|
PLoS One
|
2012
|
0.85
|
|
64
|
Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration.
|
CNS Neurol Disord Drug Targets
|
2010
|
0.84
|
|
65
|
Cortical gene transcription response patterns to water maze training in aged mice.
|
BMC Neurosci
|
2011
|
0.83
|
|
66
|
The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disorders.
|
CNS Neurol Disord Drug Targets
|
2010
|
0.82
|
|
67
|
Altered lipid and salt taste responsivity in ghrelin and GOAT null mice.
|
PLoS One
|
2013
|
0.82
|
|
68
|
Live longer sans the AT1A receptor.
|
Cell Metab
|
2009
|
0.82
|
|
69
|
Anti-inflammatory effects of physical activity in relationship to improved cognitive status in humans and mouse models of Alzheimer's disease.
|
Curr Alzheimer Res
|
2012
|
0.82
|
|
70
|
Aging and bone health in individuals with developmental disabilities.
|
Int J Endocrinol
|
2012
|
0.82
|
|
71
|
Longitudinal analysis of calorie restriction on rat taste bud morphology and expression of sweet taste modulators.
|
J Gerontol A Biol Sci Med Sci
|
2013
|
0.81
|
|
72
|
Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells.
|
J Neurosci Res
|
2012
|
0.81
|
|
73
|
BRET Biosensor Analysis of Receptor Tyrosine Kinase Functionality.
|
Front Endocrinol (Lausanne)
|
2013
|
0.81
|
|
74
|
Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells.
|
Exp Neurol
|
2008
|
0.81
|
|
75
|
Pancreas++: automated quantification of pancreatic islet cells in microscopy images.
|
Front Physiol
|
2013
|
0.80
|
|
76
|
Precursor ion exclusion for enhanced identification of plasma biomarkers.
|
Proteomics Clin Appl
|
2012
|
0.80
|
|
77
|
Effective use of latent semantic indexing and computational linguistics in biological and biomedical applications.
|
Front Physiol
|
2013
|
0.80
|
|
78
|
Inhibition of human type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment.
|
Endocrinology
|
2005
|
0.80
|
|
79
|
Altered hypothalamic protein expression in a rat model of Huntington's disease.
|
PLoS One
|
2012
|
0.79
|
|
80
|
Plurigon: three dimensional visualization and classification of high-dimensionality data.
|
Front Physiol
|
2013
|
0.78
|
|
81
|
What is the role of metabolic hormones in taste buds of the tongue.
|
Front Horm Res
|
2014
|
0.78
|
|
82
|
Identification of proteins and phosphoproteins using pulsed Q collision induced dissociation (PQD).
|
J Am Soc Mass Spectrom
|
2011
|
0.78
|
|
83
|
GnRH-mediated DAN production regulates the transcription of the GnRH receptor in gonadotrope cells.
|
Neuromolecular Med
|
2007
|
0.78
|
|
84
|
G protein-coupled receptor biased agonism: development towards future selective therapeutics.
|
Mini Rev Med Chem
|
2012
|
0.78
|
|
85
|
Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice.
|
PLoS One
|
2013
|
0.78
|
|
86
|
Discovery- and target-based protein quantification using iTRAQ and pulsed Q collision induced dissociation (PQD).
|
J Proteomics
|
2012
|
0.77
|
|
87
|
Metabolic context regulates distinct hypothalamic transcriptional responses to antiaging interventions.
|
Int J Endocrinol
|
2012
|
0.77
|
|
88
|
Therapeutic potential of vasoactive intestinal peptide and its receptors in neurological disorders.
|
CNS Neurol Disord Drug Targets
|
2010
|
0.76
|
|
89
|
Progressive and unconventional pharmacotherapeutic approaches to Alzheimer's disease therapy.
|
Curr Alzheimer Res
|
2012
|
0.76
|
|
90
|
Neonatal estrogenic effects upon the male rat pituitary: early gonadotrophin attenuation precedes long-term recovery.
|
Neuromolecular Med
|
2009
|
0.76
|
|
91
|
The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases.
|
Am J Alzheimers Dis (Columbia)
|
2013
|
0.76
|
|
92
|
Inhibitory actions of the NRG-1/ErbB4 pathway in macrophages during tissue fibrosis in heart, skin and lung.
|
Am J Physiol Heart Circ Physiol
|
2017
|
0.75
|
|
93
|
New frontiers in G protein-coupled receptor regulation of neurological disorders.
|
CNS Neurol Disord Drug Targets
|
2010
|
0.75
|