| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
A class of potent antimalarials and their specific accumulation in infected erythrocytes.
|
Science
|
2002
|
2.27
|
|
2
|
In vivo antimalarial activities of mono- and bis quaternary ammonium salts interfering with Plasmodium phospholipid metabolism.
|
Antimicrob Agents Chemother
|
2003
|
1.25
|
|
3
|
Phosphatidylinositol 3-phosphate, an essential lipid in Plasmodium, localizes to the food vacuole membrane and the apicoplast.
|
Eukaryot Cell
|
2010
|
1.16
|
|
4
|
Characterization of the choline carrier of Plasmodium falciparum: a route for the selective delivery of novel antimalarial drugs.
|
Blood
|
2004
|
1.16
|
|
5
|
Potent inhibitors of Plasmodium phospholipid metabolism with a broad spectrum of in vitro antimalarial activities.
|
Antimicrob Agents Chemother
|
2003
|
1.14
|
|
6
|
Glycerophospholipid acquisition in Plasmodium - a puzzling assembly of biosynthetic pathways.
|
Int J Parasitol
|
2010
|
1.04
|
|
7
|
Symmetrical choline-derived dications display strong anti-kinetoplastid activity.
|
J Antimicrob Chemother
|
2010
|
1.01
|
|
8
|
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis.
|
PLoS Pathog
|
2011
|
0.99
|
|
9
|
Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.
|
Antimicrob Agents Chemother
|
2006
|
0.96
|
|
10
|
Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei.
|
Mol Biochem Parasitol
|
2009
|
0.92
|
|
11
|
Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation.
|
Cell Microbiol
|
2011
|
0.92
|
|
12
|
Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways.
|
J Lipid Res
|
2010
|
0.90
|
|
13
|
The Kennedy phospholipid biosynthesis pathways are refractory to genetic disruption in Plasmodium berghei and therefore appear essential in blood stages.
|
Mol Biochem Parasitol
|
2010
|
0.89
|
|
14
|
A 24 bp cis-acting element essential for the transcriptional activity of Plasmodium falciparum CDP-diacylglycerol synthase gene promoter.
|
Mol Biochem Parasitol
|
2002
|
0.88
|
|
15
|
Statistical model to evaluate in vivo activities of antimalarial drugs in a Plasmodium cynomolgi-macaque model for Plasmodium vivax malaria.
|
Antimicrob Agents Chemother
|
2008
|
0.88
|
|
16
|
Dual molecules as new antimalarials.
|
Comb Chem High Throughput Screen
|
2005
|
0.87
|
|
17
|
A novel live-dead staining methodology to study malaria parasite viability.
|
Malar J
|
2013
|
0.85
|
|
18
|
Genetic and transcriptional analysis of phosphoinositide-specific phospholipase C in Plasmodium.
|
Exp Parasitol
|
2011
|
0.80
|
|
19
|
Characterisation of the phosphatidylinositol synthase gene of Plasmodium species.
|
Res Microbiol
|
2006
|
0.80
|
|
20
|
Quantification of antimalarial bisthiazolium compounds and their neutral bioprecursors in plasma by liquid chromatography-electrospray mass spectrometry.
|
Clin Chem
|
2005
|
0.79
|
|
21
|
Characterization of choline uptake in Trypanosoma brucei procyclic and bloodstream forms.
|
Mol Biochem Parasitol
|
2013
|
0.79
|
|
22
|
Pharmacological properties of a new antimalarial bisthiazolium salt, T3, and a corresponding prodrug, TE3.
|
Antimicrob Agents Chemother
|
2005
|
0.78
|
|
23
|
New bis-thiazolium analogues as potential antimalarial agents: design, synthesis, and biological evaluation.
|
J Med Chem
|
2013
|
0.78
|
|
24
|
PG12, a phospholipid analog with potent antimalarial activity, inhibits Plasmodium falciparum CTP:phosphocholine cytidylyltransferase activity.
|
J Biol Chem
|
2011
|
0.78
|
|
25
|
Liquid chromatography-electrospray mass spectrometry determination of a bis-thiazolium compound with potent antimalarial activity and its neutral bioprecursor in human plasma, whole blood and red blood cells.
|
J Chromatogr B Analyt Technol Biomed Life Sci
|
2005
|
0.78
|
|
26
|
Plasmodium CDP-DAG synthase: an atypical gene with an essential N-terminal extension.
|
Int J Parasitol
|
2010
|
0.78
|
|
27
|
Quantitation of SAR97276 in mouse tissues by rapid resolution liquid chromatography-mass spectrometry.
|
J Sep Sci
|
2009
|
0.78
|
|
28
|
Disulfide prodrugs of albitiazolium (T3/SAR97276): synthesis and biological activities.
|
J Med Chem
|
2012
|
0.76
|
|
29
|
Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria.
|
Nat Commun
|
2017
|
0.75
|
|
30
|
Kinetic modelling of phospholipid synthesis in Plasmodium knowlesi unravels crucial steps and relative importance of multiple pathways.
|
BMC Syst Biol
|
2013
|
0.75
|
|
31
|
Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors.
|
Eur J Pharm Sci
|
2010
|
0.75
|