PubRank

Joseph A Baur

Author PubWeight™ 62.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science 2012 6.69
2 Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell 2007 6.47
3 Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008 6.22
4 Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 2010 5.54
5 SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 2007 4.66
6 SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab 2012 3.69
7 Rapalogs and mTOR inhibitors as anti-aging therapeutics. J Clin Invest 2013 2.14
8 Design and synthesis of compounds that extend yeast replicative lifespan. Aging Cell 2006 1.93
9 SRT1720 improves survival and healthspan of obese mice. Sci Rep 2011 1.81
10 What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One 2011 1.74
11 Resveratrol and health--a comprehensive review of human clinical trials. Mol Nutr Food Res 2011 1.68
12 Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy. Aging (Albany NY) 2009 1.62
13 Extended wakefulness: compromised metabolics in and degeneration of locus ceruleus neurons. J Neurosci 2014 1.59
14 Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci 2012 1.29
15 Resveratrol and life extension. Ann N Y Acad Sci 2011 1.23
16 Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive. Aging Cell 2013 1.20
17 Dietary restriction: standing up for sirtuins. Science 2010 1.17
18 Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. Cell Metab 2013 1.14
19 Telomere length regulates ISG15 expression in human cells. Aging (Albany NY) 2009 1.13
20 Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance. Aging (Albany NY) 2013 1.07
21 Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2. Front Genet 2012 1.03
22 Challenges of translating basic research into therapeutics: resveratrol as an example. J Gerontol A Biol Sci Med Sci 2011 1.03
23 Mitochondrial protection by resveratrol. Exerc Sport Sci Rev 2011 0.98
24 Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium. Int J Cardiol 2012 0.97
25 Mitochondrial genome sequence analysis: a custom bioinformatics pipeline substantially improves Affymetrix MitoChip v2.0 call rate and accuracy. BMC Bioinformatics 2011 0.95
26 SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass. Aging Cell 2014 0.94
27 Primary respiratory chain disease causes tissue-specific dysregulation of the global transcriptome and nutrient-sensing signaling network. PLoS One 2013 0.88
28 Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock. J Trauma Acute Care Surg 2014 0.81
29 mTOR: more targets of resveratrol? Expert Rev Mol Med 2013 0.81
30 Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell 2013 0.80
31 Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock. Shock 2015 0.77
32 Obesity: do grapes hold the answer? Pediatr Res 2007 0.75
33 Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metab 2017 0.75