Published in Proc Natl Acad Sci U S A on March 14, 2011
D-aspartate and Therapeutic Exercise (DAsp&TerapEx) | NCT03228524
A restricted cell population propagates glioblastoma growth after chemotherapy. Nature (2012) 8.88
Pattern separation: a common function for new neurons in hippocampus and olfactory bulb. Neuron (2011) 2.54
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nat Neurosci (2012) 2.15
Distinct Contribution of Adult-Born Hippocampal Granule Cells to Context Encoding. Neuron (2016) 1.65
Role of adult hippocampal neurogenesis in persistent pain. Pain (2016) 1.56
Depression, stress, epilepsy and adult neurogenesis. Exp Neurol (2011) 1.18
Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials. Radiat Oncol J (2014) 1.16
Adult neurogenesis modifies excitability of the dentate gyrus. Front Neural Circuits (2013) 1.13
Neurogenesis in the dentate gyrus: carrying the message or dictating the tone. Front Neurosci (2013) 1.06
Adult neurogenesis in the mammalian hippocampus: why the dentate gyrus? Learn Mem (2013) 1.04
A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP. Neuron (2012) 1.02
Adult Hippocampal Neurogenesis, Fear Generalization, and Stress. Neuropsychopharmacology (2015) 1.01
Suppression of adult neurogenesis increases the acute effects of kainic acid. Exp Neurol (2014) 0.97
Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy. J Neurosci (2016) 0.93
Physical exercise prevents stress-induced activation of granule neurons and enhances local inhibitory mechanisms in the dentate gyrus. J Neurosci (2013) 0.93
Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus. Proc Natl Acad Sci U S A (2012) 0.93
Paradox of pattern separation and adult neurogenesis: A dual role for new neurons balancing memory resolution and robustness. Neurobiol Learn Mem (2015) 0.90
Experience-Dependent Regulation of Dentate Gyrus Excitability by Adult-Born Granule Cells. J Neurosci (2015) 0.87
Identification of a neurovascular signaling pathway regulating seizures in mice. Ann Clin Transl Neurol (2015) 0.81
Adult Hippocampal Neurogenesis Modulates Fear Learning through Associative and Nonassociative Mechanisms. J Neurosci (2015) 0.80
A Transgenic Rat for Specifically Inhibiting Adult Neurogenesis. eNeuro (2016) 0.79
Toward more predictive genetic mouse models of Alzheimer's disease. Brain Res Bull (2015) 0.79
The adaptive significance of adult neurogenesis: an integrative approach. Front Neuroanat (2013) 0.78
Potential implications of a monosynaptic pathway from mossy cells to adult-born granule cells of the dentate gyrus. Front Syst Neurosci (2015) 0.78
Activation of latent precursors in the hippocampus is dependent on long-term potentiation. Transl Psychiatry (2012) 0.78
A mid-life vitamin A supplementation prevents age-related spatial memory deficits and hippocampal neurogenesis alterations through CRABP-I. PLoS One (2013) 0.77
Cecal Ligation and Puncture Results in Long-Term Central Nervous System Myeloid Inflammation. PLoS One (2016) 0.77
Adult Neurogenesis: Opening the Gates of Troy From the Inside. Epilepsy Curr (2015) 0.76
Atrophy of pyramidal neurons and increased stress-induced glutamate levels in CA3 following chronic suppression of adult neurogenesis. Brain Struct Funct (2013) 0.76
Conditional Disabled-1 Deletion in Mice Alters Hippocampal Neurogenesis and Reduces Seizure Threshold. Front Neurosci (2016) 0.75
Young adult born neurons enhance hippocampal dependent performance via influences on bilateral networks. Elife (2016) 0.75
Adult-born neurons modify excitatory synaptic transmission to existing neurons. Elife (2017) 0.75
Fornix deep brain stimulation induced long-term spatial memory independent of hippocampal neurogenesis. Brain Struct Funct (2016) 0.75
Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin-CreERT2/Diphtheria Toxin Fragment A Transgenic Mice. PLoS One (2016) 0.75
Evaluation of a C57BL/6J × 129S1/SvImJ Hybrid Nestin-Thymidine Kinase Transgenic Mouse Model for Studying the Functional Significance of Exercise-Induced Adult Hippocampal Neurogenesis. Brain Plast (2015) 0.75
Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci (1999) 12.50
Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J Neurosci (1996) 9.84
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol (1965) 9.18
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci (2010) 8.09
Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci (1999) 7.17
Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. Nature (2004) 6.15
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat Neurosci (2008) 6.13
Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron (1993) 6.07
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus. Proc Natl Acad Sci U S A (2006) 5.83
Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus. Nat Neurosci (2007) 5.80
Transient expression of doublecortin during adult neurogenesis. J Comp Neurol (2003) 5.61
Irradiation induces neural precursor-cell dysfunction. Nat Med (2002) 5.46
A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain. Neuron (2007) 5.31
NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature (2006) 4.01
Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci (1997) 4.00
Neuronal differentiation in the adult hippocampus recapitulates embryonic development. J Neurosci (2005) 3.98
Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus (2002) 3.91
Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience (1993) 3.84
Effects of adult neurogenesis on synaptic plasticity in the rat dentate gyrus. J Neurophysiol (2001) 3.29
Spatial relational memory requires hippocampal adult neurogenesis. PLoS One (2008) 3.23
The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sets of glycinergic as well as GABAergic neurons. J Neurosci (1998) 2.76
Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies. PLoS One (2009) 2.51
Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. Cell (2009) 2.43
Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior. Proc Natl Acad Sci U S A (2008) 2.35
Long-term potentiation enhances neurogenesis in the adult dentate gyrus. J Neurosci (2006) 1.79
Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons. Neuroscience (1992) 1.67
Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies. Ann Neurol (2007) 1.64
Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation. J Neurosci (2010) 1.45
Reversal of hippocampal neuronal maturation by serotonergic antidepressants. Proc Natl Acad Sci U S A (2010) 1.37
Functional maturation of adult-generated granule cells. Hippocampus (2006) 1.36
Genetically increased cell-intrinsic excitability enhances neuronal integration into adult brain circuits. Neuron (2010) 1.35
Postnatal changes of vesicular glutamate transporter (VGluT)1 and VGluT2 immunoreactivities and their colocalization in the mouse forebrain. J Comp Neurol (2005) 1.32
Adrenal steroids regulate postnatal development of the rat dentate gyrus: I. Effects of glucocorticoids on cell death. J Comp Neurol (1991) 1.20
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learn Mem (2006) 1.16
Conditional ablation and recovery of forebrain neurogenesis in the mouse. J Comp Neurol (2009) 1.11
Inverse relationship between adult hippocampal cell proliferation and synaptic rewiring in the dentate gyrus. Hippocampus (2008) 1.03
Ongoing interplay between the neural network and neurogenesis in the adult hippocampus. Curr Opin Neurobiol (2010) 0.94
De novo mutations in epileptic encephalopathies. Nature (2013) 7.42
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Nature (2002) 3.05
Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell (2008) 2.65
Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nat Neurosci (2003) 2.35
Forebrain neurogenesis after focal Ischemic and traumatic brain injury. Neurobiol Dis (2009) 2.11
The L-Type voltage-gated calcium channel Cav1.3 mediates consolidation, but not extinction, of contextually conditioned fear in mice. Learn Mem (2006) 1.87
Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke. J Neurosci (2006) 1.85
The developmental stage of dentate granule cells dictates their contribution to seizure-induced plasticity. J Neurosci (2010) 1.78
Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci (2005) 1.68
L-type voltage-gated calcium channels in conditioned fear: a genetic and pharmacological analysis. Learn Mem (2008) 1.57
Adult neurogenesis and the ischemic forebrain. J Cereb Blood Flow Metab (2006) 1.53
Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism. Ann Neurol (2013) 1.45
Neonatal hypoxic-ischemic injury increases forebrain subventricular zone neurogenesis in the mouse. Neurobiol Dis (2004) 1.44
Hypoxic-ischemic injury stimulates subventricular zone proliferation and neurogenesis in the neonatal rat. Pediatr Res (2005) 1.29
Sox3 expression identifies neural progenitors in persistent neonatal and adult mouse forebrain germinative zones. J Comp Neurol (2006) 1.28
Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus. J Neurosci (2007) 1.27
Conditional forebrain deletion of the L-type calcium channel Ca V 1.2 disrupts remote spatial memories in mice. Learn Mem (2008) 1.23
Olfactory discrimination deficits in mice lacking the dopamine transporter or the D2 dopamine receptor. Behav Brain Res (2006) 1.21
Mechanisms and functional significance of aberrant seizure-induced hippocampal neurogenesis. Epilepsia (2008) 1.13
Conditional gene expression and lineage tracing of tuba1a expressing cells during zebrafish development and retina regeneration. J Comp Neurol (2010) 1.13
Conditional ablation and recovery of forebrain neurogenesis in the mouse. J Comp Neurol (2009) 1.11
Multiple forms of activity-dependent competition refine hippocampal circuits in vivo. Neuron (2011) 1.08
Retinoic acid regulates postnatal neurogenesis in the murine subventricular zone-olfactory bulb pathway. Development (2005) 1.06
Retinoic acid and environmental enrichment alter subventricular zone and striatal neurogenesis after stroke. Exp Neurol (2008) 0.97
Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. PLoS One (2013) 0.96
Cell-autonomous inactivation of the reelin pathway impairs adult neurogenesis in the hippocampus. J Neurosci (2012) 0.96
A genetic and functional relationship between T cells and cellular proliferation in the adult hippocampus. PLoS Biol (2010) 0.95
Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability. Proc Natl Acad Sci U S A (2012) 0.94
Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons. Hippocampus (2011) 0.94
Impaired long-term potentiation and enhanced neuronal excitability in the amygdala of Ca(V)1.3 knockout mice. Neurobiol Learn Mem (2009) 0.93
Neurogenesis is enhanced and mossy fiber sprouting arises in FGF7-deficient mice during development. Mol Cell Neurosci (2012) 0.89
Damage control: the influence of environment on recovery from brain injury. Neurology (2002) 0.87
Deletion of the mouse homolog of KCNAB2, a gene linked to monosomy 1p36, results in associative memory impairments and amygdala hyperexcitability. J Neurosci (2011) 0.87
Intact and injured endothelial cells differentially modulate postnatal murine forebrain neural stem cells. Neurobiol Dis (2009) 0.87
Iron overload decreases CaV1.3-dependent L-type Ca2+ currents leading to bradycardia, altered electrical conduction, and atrial fibrillation. Circ Arrhythm Electrophysiol (2011) 0.86
Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes. Adv Healthc Mater (2013) 0.86
Use of short hairpin RNA expression vectors to study mammalian neural development. Methods Enzymol (2005) 0.85
From network structure to network reorganization: implications for adult neurogenesis. Phys Biol (2010) 0.83
Direct transcriptional induction of Gadd45gamma by Ascl1 during neuronal differentiation. Mol Cell Neurosci (2010) 0.82
A dynamical role for acetylcholine in synaptic renormalization. PLoS Comput Biol (2013) 0.80
Conversion of short-term to long-term memory in the novel object recognition paradigm. Neurobiol Learn Mem (2013) 0.80
Formulation of current density weighted indices for correspondence between functional MRI and electrocortical stimulation maps. Clin Neurophysiol (2008) 0.80
Persistent hippocampal neurogenesis and epilepsy. Epilepsia (2008) 0.80
Laforin prevents stress-induced polyglucosan body formation and Lafora disease progression in neurons. Mol Neurobiol (2013) 0.79
Replacing neocortical neurons after stroke. Ann Neurol (2007) 0.79
Hepatocyte growth factor acts as a mitogen and chemoattractant for postnatal subventricular zone-olfactory bulb neurogenesis. Mol Cell Neurosci (2011) 0.79
Microglial expression of chemokine receptor CCR5 during rat forebrain development and after perinatal hypoxia-ischemia. J Neuroimmunol (2006) 0.79
Excitotoxic brain injury in adult zebrafish stimulates neurogenesis and long-distance neuronal integration. Glia (2014) 0.79
Waiting for Gadd45b. Epilepsy Curr (2009) 0.77
Highly-restricted, cell-specific expression of the simian CMV-IE promoter in transgenic zebrafish with age and after heat shock. Gene Expr Patterns (2008) 0.77
Of mice and intrinsic excitability: genetic background affects the size of the postburst afterhyperpolarization in CA1 pyramidal neurons. J Neurophysiol (2011) 0.77
When newborn neurons stray. Epilepsy Curr (2005) 0.76
Of fish and men. Epilepsy Curr (2014) 0.75
Ganglionic eminence graft pre-eminence in epilepsy. Nat Neurosci (2013) 0.75
Pten-less dentate granule cells make fits. Neuron (2012) 0.75
Using Patient-Derived Induced Pluripotent Stem Cells to Model and Treat Epilepsies. Curr Neurol Neurosci Rep (2015) 0.75
Turning skin into brain: using patient-derived cells to model X-linked adrenoleukodystrophy. Ann Neurol (2011) 0.75
Runaway dendrites: blame the older siblings. Epilepsy Curr (2012) 0.75
Go Out and Play; Your Brain Needs the Exercise. Epilepsy Curr (2015) 0.75
The Heat is On: L-type Calcium Channels and Febrile Seizures. Epilepsy Curr (2014) 0.75
DREADDnoughts Join in the Battle for Seizure Control. Epilepsy Curr (2015) 0.75
Leaks That Could Kill. Epilepsy Curr (1) 0.75
Speech preservation during language-dominant, left temporal lobe seizures: report of a rare, potentially misleading finding. Epilepsia (2006) 0.75