Published in Ann Neurol on November 01, 2007
Chemotherapy disrupts learning, neurogenesis and theta activity in the adult brain. Eur J Neurosci (2012) 2.34
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Compensatory network changes in the dentate gyrus restore long-term potentiation following ablation of neurogenesis in young-adult mice. Proc Natl Acad Sci U S A (2011) 1.65
Neural precursor cells and central nervous system radiation sensitivity. Semin Radiat Oncol (2009) 1.54
Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain. Proc Natl Acad Sci U S A (2008) 1.48
Exercise training for neural recovery in a restricted sample of pediatric brain tumor survivors: a controlled clinical trial with crossover of training versus no training. Neuro Oncol (2017) 1.40
Cognitive functions in primary CNS lymphoma after single or combined modality regimens. Neuro Oncol (2011) 1.25
Neurocognitive function after radiotherapy for paediatric brain tumours. Nat Rev Neurol (2012) 1.19
Cranial irradiation increases risk of stroke in pediatric brain tumor survivors. Stroke (2012) 1.18
Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis. Behav Brain Res (2011) 1.16
The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. Int J Radiat Oncol Biol Phys (2009) 1.13
Conditional ablation and recovery of forebrain neurogenesis in the mouse. J Comp Neurol (2009) 1.11
CCR2 deficiency prevents neuronal dysfunction and cognitive impairments induced by cranial irradiation. Cancer Res (2012) 1.09
Radiation-induced cognitive impairment--from bench to bedside. Neuro Oncol (2012) 1.08
Daily exercise improves memory, stimulates hippocampal neurogenesis and modulates immune and neuroimmune cytokines in aging rats. Brain Behav Immun (2012) 1.02
Could adult hippocampal neurogenesis be relevant for human behavior? Behav Brain Res (2011) 1.01
Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation. Cancer Res (2010) 1.01
Environmental enrichment restores neurogenesis and rapid acquisition in aged rats. Neurobiol Aging (2012) 0.98
Radiation-induced reductions in neurogenesis are ameliorated in mice deficient in CuZnSOD or MnSOD. Free Radic Biol Med (2009) 0.98
Consequences of cancer treatments on adult hippocampal neurogenesis: implications for cognitive function and depressive symptoms. Neuro Oncol (2014) 0.96
Neurogenesis, exercise, and cognitive late effects of pediatric radiotherapy. Neural Plast (2013) 0.92
Renin-angiotensin system blockers and modulation of radiation-induced brain injury. Curr Drug Targets (2010) 0.92
Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation. Cell Death Dis (2010) 0.89
Cognitive Sparing during the Administration of Whole Brain Radiotherapy and Prophylactic Cranial Irradiation: Current Concepts and Approaches. J Oncol (2010) 0.89
Functional and structural differences in the hippocampus associated with memory deficits in adult survivors of acute lymphoblastic leukemia. Pediatr Blood Cancer (2012) 0.88
Absence of CCL2 is sufficient to restore hippocampal neurogenesis following cranial irradiation. Brain Behav Immun (2012) 0.85
The PPARδ agonist GW0742 inhibits neuroinflammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation. Free Radic Biol Med (2013) 0.85
Decreased cytogenesis in the granule cell layer of the hippocampus and impaired place learning after irradiation of the young mouse brain evaluated using the IntelliCage platform. Exp Brain Res (2009) 0.85
Impact of social status and antidepressant treatment on neurogenesis in the baboon hippocampus. Neuropsychopharmacology (2014) 0.84
The peroxisomal proliferator-activated receptor (PPAR) α agonist, fenofibrate, prevents fractionated whole-brain irradiation-induced cognitive impairment. Radiat Res (2014) 0.84
Blockade of Kv1.3 channels ameliorates radiation-induced brain injury. Neuro Oncol (2013) 0.84
Role of PPARs in Radiation-Induced Brain Injury. PPAR Res (2009) 0.83
Hippocampal volumes in patients exposed to low-dose radiation to the basal brain. A case-control study in long-term survivors from cancer in the head and neck region. Radiat Oncol (2012) 0.83
Using lithium as a neuroprotective agent in patients with cancer. BMC Med (2012) 0.82
Critical combinations of radiation dose and volume predict intelligence quotient and academic achievement scores after craniospinal irradiation in children with medulloblastoma. Int J Radiat Oncol Biol Phys (2014) 0.80
Congruence of vascular network remodeling and neuronal dispersion in the hippocampus of reelin-deficient mice. Histochem Cell Biol (2012) 0.80
Cellular response of the rat brain to single doses of (137)Cs γ rays does not predict its response to prolonged 'biologically equivalent' fractionated doses. Int J Radiat Biol (2014) 0.80
Low-doses of cisplatin injure hippocampal synapses: a mechanism for 'chemo' brain? Exp Neurol (2014) 0.80
Hippocampal proliferation is increased in presymptomatic Parkinson's disease and due to microglia. Neural Plast (2014) 0.80
Neural stem cell sparing by linac based intensity modulated stereotactic radiotherapy in intracranial tumors. Radiat Oncol (2013) 0.79
Lipopolysaccharide sensitized male and female juvenile brains to ionizing radiation. Cell Death Dis (2013) 0.79
Enhanced lithium-induced brain recovery following cranial irradiation is not impeded by inflammation. Stem Cells Transl Med (2012) 0.79
Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours. Nat Rev Neurol (2016) 0.79
Neurological complications following treatment of children with brain tumors. J Pediatr Rehabil Med (2011) 0.78
Aging-like changes in the transcriptome of irradiated microglia. Glia (2015) 0.77
Molecular, Cellular and Functional Effects of Radiation-Induced Brain Injury: A Review. Int J Mol Sci (2015) 0.77
Some hormone, cytokine and chemokine levels that change across lifespan vary by cognitive status in male Fischer 344 rats. Brain Behav Immun (2015) 0.77
Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats. PLoS One (2015) 0.77
Ionizing Radiation Perturbs Cell Cycle Progression of Neural Precursors in the Subventricular Zone Without Affecting Their Long-Term Self-Renewal. ASN Neuro (2015) 0.76
Radiation-induced changes in normal-appearing gray matter in patients with nasopharyngeal carcinoma: a magnetic resonance imaging voxel-based morphometry study. Neuroradiology (2014) 0.76
Modeling Heavy-Ion Impairment of Hippocampal Neurogenesis after Acute and Fractionated Irradiation. Radiat Res (2016) 0.75
Cognitive Remediation Therapy for Brain Tumor Survivors with Cognitive Deficits. Cureus (2015) 0.75
C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning. Oncotarget (2016) 0.75
The impact of high and low dose ionising radiation on the central nervous system. Redox Biol (2016) 0.75
Dose-dependent short- and long-term effects of ionizing irradiation on neural stem cells in murine hippocampal tissue cultures: neuroprotective potential of resveratrol. Brain Behav (2016) 0.75
Potential applications of imaging and image-guided radiotherapy for brain metastases and glioblastoma to improve patient quality of life. Front Oncol (2013) 0.75
Once the Light Touch to the Brain: Cytotoxic Effects of Low-Dose Gamma-Ray, Laser Light, and Visible Light on Rat Neuronal Cell Culture. Eurasian J Med (2016) 0.75
Radiation-Induced Growth Retardation and Microstructural and Metabolite Abnormalities in the Hippocampus. Neural Plast (2016) 0.75
No clinically relevant effect on cognitive outcomes after low-dose radiation to the infant brain: a population-based cohort study in Sweden. Acta Oncol (2014) 0.75
Prospective assessment of white matter integrity in adult stem cell transplant recipients. Brain Imaging Behav (2016) 0.75
Cisplatin-induced mitochondrial dysfunction is associated with impaired cognitive function in rats. Free Radic Biol Med (2016) 0.75
Cognitive effects of donepezil therapy in patients with brain tumors: a pilot study. J Neurooncol (2016) 0.75
Lithium protects hippocampal progenitors, cognitive performance and hypothalamus-pituitary function after irradiation to the juvenile rat brain. Oncotarget (2017) 0.75
Chemoradiation impairs normal developmental cortical thinning in medulloblastoma. J Neurooncol (2017) 0.75
Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev (2007) 17.20
Functional neurogenesis in the adult hippocampus. Nature (2002) 11.17
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science (2007) 10.60
Inflammatory blockade restores adult hippocampal neurogenesis. Science (2003) 10.14
p16INK4a induces an age-dependent decline in islet regenerative potential. Nature (2006) 9.09
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci U S A (2006) 5.78
Profiling critical cancer gene mutations in clinical tumor samples. PLoS One (2009) 5.63
Irradiation induces neural precursor-cell dysfunction. Nat Med (2002) 5.46
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell (2002) 5.11
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature (2008) 5.00
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proc Natl Acad Sci U S A (2008) 4.97
CHD5 is a tumor suppressor at human 1p36. Cell (2007) 4.90
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities. Cancer Res (2006) 4.80
Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell (2011) 4.78
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. Cancer Cell (2008) 4.71
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell (2008) 4.68
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature (2012) 4.37
Molecular heterogeneity in acute renal allograft rejection identified by DNA microarray profiling. N Engl J Med (2003) 4.35
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev (2007) 4.16
NFKBIA deletion in glioblastomas. N Engl J Med (2010) 3.96
Extreme sensitivity of adult neurogenesis to low doses of X-irradiation. Cancer Res (2003) 3.81
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell (2011) 3.78
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice. J Clin Invest (2010) 3.74
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nat Med (2011) 3.66
FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell (2009) 3.54
Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev (2012) 3.44
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell (2009) 3.37
Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet (2006) 3.34
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet (2013) 3.19
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. Science (2014) 3.11
Excitation-neurogenesis coupling in adult neural stem/progenitor cells. Neuron (2004) 3.09
A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Res (2006) 3.06
p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev (2005) 3.02
A network model of a cooperative genetic landscape in brain tumors. JAMA (2009) 2.86
Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron (2012) 2.84
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. Lancet Oncol (2013) 2.82
VEGF is necessary for exercise-induced adult hippocampal neurogenesis. Eur J Neurosci (2003) 2.78
Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas. Cancer Res (2010) 2.56
Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. Cancer Res (2005) 2.54
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat Genet (2013) 2.42
A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome. Am J Med Genet A (2013) 2.35
Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Sci Transl Med (2013) 2.31
Profile of daily life in children with brain tumors: an assessment of health-related quality of life. J Clin Oncol (2005) 2.26
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell (2009) 2.18
Wnt-mediated self-renewal of neural stem/progenitor cells. Proc Natl Acad Sci U S A (2008) 2.15
TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol (2009) 2.15
Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation (2005) 2.12
High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. Cancer Res (2005) 2.10
BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications. PLoS One (2011) 2.04
Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci U S A (2007) 2.03
Late profound muscle weakness following heart transplantation due to Danon disease. Muscle Nerve (2012) 1.97
Human glioma growth is controlled by microRNA-10b. Cancer Res (2011) 1.96
Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors. Proc Natl Acad Sci U S A (2013) 1.95
Clinical spectrum, morbidity, and mortality in 113 pediatric patients with mitochondrial disease. Pediatrics (2004) 1.95
Embryonic stem cell transcription factor signatures in the diagnosis of primary and metastatic germ cell tumors. Am J Surg Pathol (2007) 1.92
The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell (2011) 1.92
Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol (2006) 1.90
Myelin abnormalities without oligodendrocyte loss in periventricular leukomalacia. Brain Pathol (2008) 1.87
Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proc Natl Acad Sci U S A (2011) 1.86
Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc Natl Acad Sci U S A (2011) 1.82
Monosomy of chromosome 10 associated with dysregulation of epidermal growth factor signaling in glioblastomas. JAMA (2009) 1.81
Molecular diversity of astrocytes with implications for neurological disorders. Proc Natl Acad Sci U S A (2004) 1.76
ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Cell Stem Cell (2011) 1.75
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. J Exp Med (2011) 1.74
Sleep restriction suppresses neurogenesis induced by hippocampus-dependent learning. J Neurophysiol (2005) 1.72
Classifying human brain tumors by lipid imaging with mass spectrometry. Cancer Res (2011) 1.71
Drosophila models of neurodegenerative diseases. Annu Rev Pathol (2009) 1.67
Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome. Hum Mol Genet (2005) 1.67
Novel homoplasmic mutation in the mitochondrial tRNATyr gene associated with atypical mitochondrial cytopathy presenting with focal segmental glomerulosclerosis. Am J Med Genet A (2003) 1.66
Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer. Mol Cell Biol (2007) 1.65
Incidence patterns for ependymoma: a surveillance, epidemiology, and end results study. J Neurosurg (2009) 1.64
DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape. Nat Genet (2013) 1.64
Hematopoietic cells maintain hematopoietic fates upon entering the brain. J Exp Med (2005) 1.63
Immune influence on adult neural stem cell regulation and function. Neuron (2009) 1.59
Determinants of glomerular hypofiltration in aging humans. Kidney Int (2003) 1.54
Neurogenesis in rats after focal cerebral ischemia is enhanced by indomethacin. Stroke (2005) 1.54
Transplanted stem cell-secreted vascular endothelial growth factor effects poststroke recovery, inflammation, and vascular repair. Stem Cells (2011) 1.54
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors. Neuro Oncol (2011) 1.53
Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clin Cancer Res (2009) 1.52
A syndrome of irreversible leukoencephalopathy following pediatric allogeneic bone marrow transplantation. Pediatr Blood Cancer (2007) 1.51
IGF-I has a direct proliferative effect in adult hippocampal progenitor cells. Mol Cell Neurosci (2003) 1.50
Spinal pilocytic astrocytoma in an elderly patient. World Neurosurg (2011) 1.49
p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc Natl Acad Sci U S A (2006) 1.48
Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas. J Clin Oncol (2005) 1.46
Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PLoS One (2007) 1.45
Discrimination of human astrocytoma subtypes by lipid analysis using desorption electrospray ionization imaging mass spectrometry. Angew Chem Int Ed Engl (2010) 1.43
Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Mol Cell Biol (2003) 1.42
Radiation response of neural precursor cells: linking cellular sensitivity to cell cycle checkpoints, apoptosis and oxidative stress. Radiat Res (2004) 1.41
NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs. J Biol Chem (2005) 1.40
Atypical teratoid/rhabdoid tumor with ganglioglioma-like differentiation: case report and review of the literature. Hum Pathol (2013) 1.39
Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell-derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity. Mol Ther Nucleic Acids (2013) 1.38
Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's Oncology Group phase II study. Pediatr Blood Cancer (2008) 1.37
SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress. PLoS One (2011) 1.37
A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. Development (2002) 1.35
Histology-based expression profiling yields novel prognostic markers in human glioblastoma. J Neuropathol Exp Neurol (2005) 1.34
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm. Genome Res (2013) 1.33
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proc Natl Acad Sci U S A (2013) 1.33