Published in J Nat Prod on March 17, 2011
Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J (2012) 2.42
Reduction of delayed onset muscle soreness by a novel curcumin delivery system (Meriva®): a randomised, placebo-controlled trial. J Int Soc Sports Nutr (2014) 0.95
Therapeutic potential of curcumin in digestive diseases. World J Gastroenterol (2013) 0.92
Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol (2016) 0.85
Pilot study of oral administration of a curcumin-phospholipid formulation for treatment of central serous chorioretinopathy. Clin Ophthalmol (2012) 0.83
Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB- and the beta-catenin pathways. Oncotarget (2015) 0.80
Comparative absorption of curcumin formulations. Nutr J (2014) 0.80
Controlled systemic delivery by polymeric implants enhances tissue and plasma curcumin levels compared with oral administration. Eur J Pharm Biopharm (2011) 0.80
The effect of turmeric (Curcumin) supplementation on cytokine and inflammatory marker responses following 2 hours of endurance cycling. J Int Soc Sports Nutr (2015) 0.79
Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva(®)), nimesulide, and acetaminophen. J Pain Res (2013) 0.78
Beyond Yellow Curry: Assessing Commercial Curcumin Absorption Technologies. J Am Coll Nutr (2015) 0.78
Oral administration of a curcumin-phospholipid delivery system for the treatment of central serous chorioretinopathy: a 12-month follow-up study. Clin Ophthalmol (2013) 0.77
Bioavailability of a Sustained Release Formulation of Curcumin. Integr Med (Encinitas) (2014) 0.77
Synthesis and Evaluation of the Anti-Oxidant Capacity of Curcumin Glucuronides, the Major Curcumin Metabolites. Antioxidants (Basel) (2015) 0.77
Tasty and healthy TR(i)Ps. The human quest for culinary pungency. EMBO Rep (2011) 0.76
Curcumin therapy in a Plp1 transgenic mouse model of Pelizaeus-Merzbacher disease. Ann Clin Transl Neurol (2015) 0.76
Curcuma longa L. as a therapeutic agent in intestinal motility disorders. 2: Safety profile in mouse. PLoS One (2013) 0.76
Oral Curcumin (Meriva) Is Effective as an Adjuvant Treatment and Is Able to Reduce IL-22 Serum Levels in Patients with Psoriasis Vulgaris. Biomed Res Int (2015) 0.75
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids. Sci Rep (2016) 0.75
Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin. Sci Rep (2016) 0.75
Transepithelial Transport of Curcumin in Caco-2 Cells Is significantly Enhanced by Micellar Solubilisation. Plant Foods Hum Nutr (2016) 0.75
Unraveling the Anticancer Effect of Curcumin and Resveratrol. Nutrients (2016) 0.75
Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers. J Clin Pharmacol (2016) 0.75
Cryoablation and Meriva have strong therapeutic effect on triple-negative breast cancer. Oncoimmunology (2015) 0.75
Synergistic Interplay between Curcumin and Polyphenol-Rich Foods in the Mediterranean Diet: Therapeutic Prospects for Neurofibromatosis 1 Patients. Nutrients (2017) 0.75
A Realistic View on "The Essential Medicinal Chemistry of Curcumin". ACS Med Chem Lett (2017) 0.75
The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses (2009) 3.45
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci U S A (2004) 3.07
Pharmacology of vanilloid transient receptor potential cation channels. Mol Pharmacol (2009) 2.00
CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a BCR-like signalosome involving Syk, Slp65 and PLCgamma2. Eur J Immunol (2007) 1.90
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain (2011) 1.70
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses. Proc Natl Acad Sci U S A (2008) 1.66
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium. J Agric Food Chem (2007) 1.59
N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J Biol Chem (2003) 1.48
Functional characterization of transient receptor potential channels in mouse urothelial cells. Am J Physiol Renal Physiol (2009) 1.39
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis. Biochim Biophys Acta (2006) 1.31
Hyperforin inhibits cancer invasion and metastasis. Cancer Res (2004) 1.27
Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev (2010) 1.26
An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery? Angew Chem Int Ed Engl (2011) 1.26
Targeting oncogenic serine/threonine-protein kinase BRAF in cancer cells inhibits angiogenesis and abrogates hypoxia. Proc Natl Acad Sci U S A (2011) 1.16
Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse? J Med Chem (2004) 1.06
A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase. Biochem Biophys Res Commun (2004) 1.05
Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues. FEBS Lett (2002) 1.05
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain (2012) 1.03
Ischemic neuroprotection by TRPV1 receptor-induced hypothermia. J Cereb Blood Flow Metab (2012) 1.03
The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin. J Agric Food Chem (2009) 1.02
In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin. Chem Biol Interact (2008) 1.01
Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity. J Agric Food Chem (2012) 1.00
SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro. Biochem Pharmacol (2008) 0.99
Receptor agonism and antagonism of dietary bitter compounds. J Neurosci (2011) 0.99
Location of the CD8 T cell epitope within the antigenic precursor determines immunogenicity and protection against the Toxoplasma gondii parasite. PLoS Pathog (2013) 0.98
Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway. Mol Pharmacol (2003) 0.98
Immunosuppressive activity of capsaicinoids: capsiate derived from sweet peppers inhibits NF-kappaB activation and is a potent antiinflammatory compound in vivo. Eur J Immunol (2002) 0.97
Spices: the savory and beneficial science of pungency. Rev Physiol Biochem Pharmacol (2013) 0.96
Neurosyphilis and status epilepticus: case report and literature review. Epilepsy Res (2004) 0.95
Value of repeated measures of nerve conduction and quantitative sensory testing in a diabetic neuropathy trial. Muscle Nerve (2006) 0.95
MRI in DNM2-related centronuclear myopathy: evidence for highly selective muscle involvement. Neuromuscul Disord (2006) 0.95
Higher serum 25-hydroxyvitamin D concentrations associate with a faster recovery of skeletal muscle strength after muscular injury. Nutrients (2013) 0.95
Activation of latent HIV-1 expression by protein kinase C agonists. A novel therapeutic approach to eradicate HIV-1 reservoirs. Curr Drug Targets (2011) 0.93
Plant volatiles: production, function and pharmacology. Nat Prod Rep (2011) 0.93
Differential effects of phorbol-13-monoesters on human immunodeficiency virus reactivation. Biochem Pharmacol (2007) 0.93
In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study. Bioorg Med Chem Lett (2007) 0.92
Ligustilide: a novel TRPA1 modulator. Pflugers Arch (2011) 0.91
Calcium ionophoretic and apoptotic effects of ferutinin in the human Jurkat T-cell line. Biochem Pharmacol (2004) 0.91
Antiproliferative effects on tumour cells and promotion of keratinocyte wound healing by different lichen compounds. Planta Med (2009) 0.91
Circulating pro-inflammatory cytokines are elevated and peak power output correlates with 25-hydroxyvitamin D in vitamin D insufficient adults. Eur J Appl Physiol (2013) 0.91
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4alpha-phorbol esters: a structure-activity study. J Med Chem (2009) 0.91
Transient downbeat nystagmus from West Nile virus encephalomyelitis. Neurology (2006) 0.90
Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead. J Med Chem (2003) 0.90
Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel. Pain (2013) 0.89
Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-kappa B, NFAT, and activator protein 1 signaling pathways. J Immunol (2004) 0.89
A focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii. Antimicrob Agents Chemother (2012) 0.87
Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway. J Biol Chem (2004) 0.87
Anti-inflammatory and vascularprotective properties of 8-prenylapigenin. Eur J Pharmacol (2009) 0.87
Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida. Fitoterapia (2013) 0.86
Evaluation of the antioxidant and cytotoxic activity of arzanol, a prenylated alpha-pyrone-phloroglucinol etherodimer from Helichrysum italicum subsp.microphyllum. Chem Biol Interact (2006) 0.86
Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. Biochem Pharmacol (2010) 0.86
Synthesis and biological evaluation of hyperforin analogues. Part I. Modification of the enolized cyclohexanedione moiety. J Nat Prod (2002) 0.86
Denbinobin inhibits nuclear factor-kappaB and induces apoptosis via reactive oxygen species generation in human leukemic cells. Biochem Pharmacol (2009) 0.86
Antioxidant activity of capsinoids. J Agric Food Chem (2002) 0.85
A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis. J Neuroimmune Pharmacol (2012) 0.85
Dietary protein in weight management: a review proposing protein spread and change theories. Nutr Metab (Lond) (2012) 0.85
Different doses of supplemental vitamin D maintain interleukin-5 without altering skeletal muscle strength: a randomized, double-blind, placebo-controlled study in vitamin D sufficient adults. Nutr Metab (Lond) (2012) 0.85
Non-pungent capsaicinoids from sweet pepper synthesis and evaluation of the chemopreventive and anticancer potential. Eur J Nutr (2003) 0.85
Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activator protein 1 in T lymphocytes. J Pharmacol Exp Ther (2006) 0.84
Daphnane-type diterpene orthoesters and their biological activities. Mini Rev Med Chem (2002) 0.84
Antioxidant activity of oligomeric acylphloroglucinols from Myrtus communis L. Free Radic Res (2003) 0.84
Selective analysis of phenolic compounds in propolis by HPLC-MS/MS. Phytochem Anal (2008) 0.83
Umbellulone modulates TRP channels. Pflugers Arch (2011) 0.83
Protective effect of the oligomeric acylphloroglucinols from Myrtus communis on cholesterol and human low density lipoprotein oxidation. Chem Phys Lipids (2008) 0.83
Identification of molecular targets of the oligomeric nonprenylated acylphloroglucinols from Myrtus communis and their implication as anti-inflammatory compounds. J Pharmacol Exp Ther (2005) 0.83
Oxyhomologation of the amide bond potentiates neuroprotective effects of the endolipid N-palmitoylethanolamine. J Pharmacol Exp Ther (2006) 0.83
Supplemental vitamin D enhances the recovery in peak isometric force shortly after intense exercise. Nutr Metab (Lond) (2013) 0.82
8-Prenylnaringenin, inhibits estrogen receptor-alpha mediated cell growth and induces apoptosis in MCF-7 breast cancer cells. J Steroid Biochem Mol Biol (2007) 0.82
8-Prenylnaringenin inhibits epidermal growth factor-induced MCF-7 breast cancer cell proliferation by targeting phosphatidylinositol-3-OH kinase activity. J Steroid Biochem Mol Biol (2008) 0.82
Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline. Gene (2002) 0.82
Dietary protein to maximize resistance training: a review and examination of protein spread and change theories. J Int Soc Sports Nutr (2012) 0.81
Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH). Biochim Biophys Acta (2005) 0.81
Omnia praeclara rara. The quest for ingenol heats up. Angew Chem Int Ed Engl (2014) 0.81
A rat primary hepatocyte culture model for aging studies. Curr Protoc Toxicol (2008) 0.81
The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway. Br J Pharmacol (2003) 0.81
A controlled study of a lecithinized delivery system of curcumin (Meriva®) to alleviate the adverse effects of cancer treatment. Phytother Res (2013) 0.81
The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events. Biochem Pharmacol (2006) 0.80
Pterocarpans from Bituminaria morisiana and Bituminaria bituminosa. Phytochemistry (2003) 0.80
Characterization of anti-coagulant properties of prenylated coumarin ferulenol. Biochim Biophys Acta (2007) 0.79
Functionalization of β-caryophyllene generates novel polypharmacology in the endocannabinoid system. ACS Chem Biol (2014) 0.79
Comparative topical anti-inflammatory activity of cannabinoids and cannabivarins. Fitoterapia (2010) 0.79
Diterpenoids from Cascarilla (Croton eluteria Bennet). J Agric Food Chem (2002) 0.79
Iodinated N-acylvanillamines: potential "multiple-target" anti-inflammatory agents acting via the inhibition of t-cell activation and antagonism at vanilloid TRPV1 channels. Mol Pharmacol (2006) 0.79
Biological properties of jatrophane polyesters, new microtubule-interacting agents. Cancer Chemother Pharmacol (2002) 0.79
Inhibition of NF-kappaB activation and expression of inflammatory mediators by polyacetylene spiroketals from Plagius flosculosus. Biochim Biophys Acta (2005) 0.79
Flavonoid-induced autophagy in hormone sensitive breast cancer cells. Fitoterapia (2009) 0.78
Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva(®)), nimesulide, and acetaminophen. J Pain Res (2013) 0.78
Falcarindiol allosterically modulates GABAergic currents in cultured rat hippocampal neurons. J Nat Prod (2012) 0.78
Evaluation of anti-cellulite efficacy: a topical cosmetic treatment for cellulite blemishes - a multifunctional formulation. J Cosmet Sci (2011) 0.78
Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract. Fitoterapia (2012) 0.77
Protective role of arzanol against lipid peroxidation in biological systems. Chem Phys Lipids (2010) 0.77
Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT. Planta Med (2004) 0.77
Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. J Immunol (2005) 0.77
Molecular diversity and natural products. Mol Divers (2011) 0.77
A regiodivergent synthesis of ring a C-prenylflavones. Org Lett (2008) 0.77
Modulation of chemoselectivity by protein additives. Remarkable effects in the oxidation of hyperforin. J Org Chem (2004) 0.77