Published in Pflugers Arch on October 29, 2011
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
The TRPA1 channel in migraine mechanism and treatment. Br J Pharmacol (2014) 1.50
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain (2012) 1.03
TRPA1 channels in the vasculature. Br J Pharmacol (2012) 0.92
TRPV1 activation prevents nonalcoholic fatty liver through UCP2 upregulation in mice. Pflugers Arch (2012) 0.89
TRPA1 and other TRP channels in migraine. J Headache Pain (2013) 0.85
Bimodal effects of cinnamaldehyde and camphor on mouse TRPA1. Pflugers Arch (2012) 0.80
Extracranial injections of botulinum neurotoxin type A inhibit intracranial meningeal nociceptors' responses to stimulation of TRPV1 and TRPA1 channels: Are we getting closer to solving this puzzle? Cephalalgia (2016) 0.78
Terpenes and lipids of the endocannabinoid and transient-receptor-potential-channel biosignaling systems. ACS Chem Neurosci (2014) 0.77
Intraganglionic signaling as a novel nasal-meningeal pathway for TRPA1-dependent trigeminovascular activation by inhaled environmental irritants. PLoS One (2014) 0.77
Deciphering Subtype-Selective Modulations in TRPA1 Biosensor Channels. Curr Neuropharmacol (2015) 0.76
Action mechanisms of Onabotulinum toxin-A: hints for selection of eligible patients. Neurol Sci (2017) 0.75
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature (2007) 7.12
Transient receptor potential cation channels in disease. Physiol Rev (2007) 6.91
TRPA1 acts as a cold sensor in vitro and in vivo. Proc Natl Acad Sci U S A (2009) 3.46
Bimodal action of menthol on the transient receptor potential channel TRPA1. J Neurosci (2007) 2.78
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate. EMBO J (2006) 2.22
Beta-caryophyllene is a dietary cannabinoid. Proc Natl Acad Sci U S A (2008) 1.97
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain (2011) 1.70
Nicotine activates the chemosensory cation channel TRPA1. Nat Neurosci (2009) 1.44
The cell biology of smell. J Cell Biol (2010) 1.40
Alpha-thujone (the active component of absinthe): gamma-aminobutyric acid type A receptor modulation and metabolic detoxification. Proc Natl Acad Sci U S A (2000) 1.32
Irritating channels: the case of TRPA1. J Physiol (2010) 1.32
Aromatherapy facts and fictions: a scientific analysis of olfactory effects on mood, physiology and behavior. Int J Neurosci (2009) 1.28
An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery? Angew Chem Int Ed Engl (2011) 1.26
Characterisation of TRPM8 as a pharmacophore receptor. Cell Calcium (2007) 1.13
Agonist-induced changes in Ca(2+) permeation through the nociceptor cation channel TRPA1. Biophys J (2010) 1.12
CGRP receptors in the control of pain and inflammation. Curr Opin Pharmacol (2009) 1.03
The effect of thymoquinone on intractable pediatric seizures (pilot study). Epilepsy Res (2010) 0.94
Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship. J Pharm Pharm Sci (2010) 0.93
Plant volatiles: production, function and pharmacology. Nat Prod Rep (2011) 0.93
Migraine. Handb Exp Pharmacol (2009) 0.89
Pleasant natural scent with unpleasant effects: cluster headache-like attacks triggered by Umbellularia californica. Cephalalgia (2010) 0.89
Cutaneous application of menthol 10% solution as an abortive treatment of migraine without aura: a randomised, double-blind, placebo-controlled, crossed-over study. Int J Clin Pract (2010) 0.86
The role of natural products in the ligand deorphanization of TRP channels. Curr Pharm Des (2008) 0.84
Determination of ligustilide in rat brain after nasal administration of essential oil from Rhizoma Chuanxiong. Fitoterapia (2009) 0.78
Hemisynthesis of dihydroumbellulols from umbellulone: new cooling compounds. J Agric Food Chem (2010) 0.75
Determination of ligustilide in the brains of freely moving rats using microdialysis coupled with ultra performance liquid chromatography/mass spectrometry. Fitoterapia (2010) 0.75
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature (2004) 5.76
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature (2003) 4.45
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol (2003) 3.60
TRPA1 acts as a cold sensor in vitro and in vivo. Proc Natl Acad Sci U S A (2009) 3.46
The molecular receptive ranges of human TAS2R bitter taste receptors. Chem Senses (2009) 3.45
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem (2003) 3.15
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem (2002) 3.14
TRP channels: an overview. Cell Calcium (2005) 2.98
Permeation and selectivity of TRP channels. Annu Rev Physiol (2006) 2.96
TRPP2 and TRPV4 form a polymodal sensory channel complex. J Cell Biol (2008) 2.88
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells. J Biol Chem (2002) 2.87
Bimodal action of menthol on the transient receptor potential channel TRPA1. J Neurosci (2007) 2.78
Calcium absorption across epithelia. Physiol Rev (2005) 2.57
Heat activation of TRPM5 underlies thermal sensitivity of sweet taste. Nature (2005) 2.52
Sensing with TRP channels. Nat Chem Biol (2005) 2.51
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli. Nat Chem Biol (2007) 2.48
TRPV4 calcium entry channel: a paradigm for gating diversity. Am J Physiol Cell Physiol (2004) 2.35
TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron (2011) 2.31
Gating of TRP channels: a voltage connection? J Physiol (2005) 2.30
Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem (2002) 2.24
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat Genet (2008) 2.24
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate. EMBO J (2006) 2.22
Voltage dependence of the Ca2+-activated cation channel TRPM4. J Biol Chem (2003) 2.21
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. J Clin Invest (2007) 2.19
The vanilloid transient receptor potential channel TRPV4: from structure to disease. Prog Biophys Mol Biol (2009) 2.13
TRPs in our senses. Curr Biol (2008) 2.12
Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia. Am J Hum Genet (2009) 2.02
Pharmacology of vanilloid transient receptor potential cation channels. Mol Pharmacol (2009) 2.00
Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. EMBO J (2003) 1.97
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc Natl Acad Sci U S A (2010) 1.96
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. J Biol Chem (2004) 1.82
Outer pore architecture of a Ca2+-selective TRP channel. J Biol Chem (2004) 1.79
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab (2008) 1.79
PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem (2006) 1.71
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice. Cell Calcium (2005) 1.70
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system. Brain (2011) 1.70
Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4. Nat Immunol (2007) 1.68
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responses. Proc Natl Acad Sci U S A (2008) 1.66
Neuronal TRP channels: thermometers, pathfinders and life-savers. Trends Neurosci (2008) 1.63
The transient receptor potential channel TRPA1: from gene to pathophysiology. Pflugers Arch (2012) 1.63
Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium. J Agric Food Chem (2007) 1.59
The role of transient receptor potential cation channels in Ca2+ signaling. Cold Spring Harb Perspect Biol (2010) 1.56
The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil. Curr Biol (2011) 1.56
Molecular mechanism of active Ca2+ reabsorption in the distal nephron. Annu Rev Physiol (2002) 1.51
N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J Biol Chem (2003) 1.48
The loss and progressive recovery of voiding after spinal cord interruption in rats is associated with simultaneous changes in autonomous contractile bladder activity. Eur Urol (2008) 1.48
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice. Proc Natl Acad Sci U S A (2010) 1.46
Nicotine activates the chemosensory cation channel TRPA1. Nat Neurosci (2009) 1.44
Stimulation by caveolin-1 of the hypotonicity-induced release of taurine and ATP at basolateral, but not apical, membrane of Caco-2 cells. Am J Physiol Cell Physiol (2005) 1.43
De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury. Nat Med (2009) 1.42
Vanilloid transient receptor potential cation channels: an overview. Curr Pharm Des (2008) 1.40
Functional characterization of transient receptor potential channels in mouse urothelial cells. Am J Physiol Renal Physiol (2009) 1.39
Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. J Biol Chem (2007) 1.36
Modulation of TRPs by PIPs. J Physiol (2007) 1.35
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation. Pain (2011) 1.35
Irritating channels: the case of TRPA1. J Physiol (2010) 1.32
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis. Biochim Biophys Acta (2006) 1.31
Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators. Pflugers Arch (2008) 1.31
Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation. Cardiovasc Res (2008) 1.30
Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole. J Neurosci (2008) 1.30
On the origin of bladder sensing: Tr(i)ps in urology. Neurourol Urodyn (2008) 1.30
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b. Pflugers Arch (2004) 1.27
The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation. Cell Calcium (2003) 1.27
Hyperforin inhibits cancer invasion and metastasis. Cancer Res (2004) 1.27
Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev (2010) 1.26
An NMR spectroscopic method to identify and classify thiol-trapping agents: revival of Michael acceptors for drug discovery? Angew Chem Int Ed Engl (2011) 1.26
Stimulus-specific modulation of the cation channel TRPV4 by PACSIN 3. J Biol Chem (2008) 1.26
Transient receptor potential channels in mechanosensing and cell volume regulation. Methods Enzymol (2007) 1.25
Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport. EMBO J (2006) 1.25
TRP channels and mechanosensory transduction: insights into the arterial myogenic response. Pflugers Arch (2008) 1.24
The selectivity filter of the cation channel TRPM4. J Biol Chem (2005) 1.24
Where is TRPV1 expressed in the bladder, do we see the real channel? Naunyn Schmiedebergs Arch Pharmacol (2009) 1.23
Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin. J Biol Chem (2004) 1.23
Marine antimalarials. Mar Drugs (2009) 1.23
Why do we not change a journal's name? Pflugers Arch (2011) 1.21
Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. J Nat Prod (2011) 1.19
Biophysics and structure-function relationship of T-type Ca2+ channels. Cell Calcium (2006) 1.18
Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6. J Gen Physiol (2003) 1.18
Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity. J Mol Cell Biol (2012) 1.17
TRP channels. Compr Physiol (2012) 1.17