Published in Proc Natl Acad Sci U S A on September 01, 1990
Porters versus rowers: a unified stochastic model of motor proteins. J Cell Biol (1993) 2.15
Multiple- and single-molecule analysis of the actomyosin motor by nanometer-piconewton manipulation with a microneedle: unitary steps and forces. Biophys J (1996) 2.07
Higher plant myosin XI moves processively on actin with 35 nm steps at high velocity. EMBO J (2003) 1.85
Rapid dissociation and reassociation of actomyosin cross-bridges during force generation: a newly observed facet of cross-bridge action in muscle. Proc Natl Acad Sci U S A (1991) 1.69
Calcium regulation of skeletal muscle thin filament motility in vitro. Biophys J (1997) 1.64
Movement of single myosin filaments and myosin step size on an actin filament suspended in solution by a laser trap. Biophys J (1994) 1.33
Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis. Nat Rev Mol Cell Biol (2010) 1.27
Comparative single-molecule and ensemble myosin enzymology: sulfoindocyanine ATP and ADP derivatives. Biophys J (2000) 1.17
Frozen steady states in active systems. Proc Natl Acad Sci U S A (2011) 1.11
A molecular model of phosphorylation-based activation and potentiation of tarantula muscle thick filaments. J Mol Biol (2011) 1.00
Flexibility of myosin attachment to surfaces influences F-actin motion. Biophys J (1995) 1.00
Sliding distance per ATP molecule hydrolyzed by myosin heads during isotonic shortening of skinned muscle fibers. Biophys J (1995) 0.98
Myofilament sliding per ATP molecule in rabbit muscle fibres studied using laser flash photolysis of caged ATP. J Physiol (1993) 0.92
Control of actin moving trajectory by patterned poly(methylmethacrylate) tracks. Biophys J (1997) 0.92
Creation of functional micro/nano systems through top-down and bottom-up approaches. Mol Cell Biomech (2009) 0.91
Single molecule measurements and molecular motors. Philos Trans R Soc Lond B Biol Sci (2008) 0.91
Head of myosin IX binds calmodulin and moves processively toward the plus-end of actin filaments. J Biol Chem (2010) 0.91
Translational actomyosin research: fundamental insights and applications hand in hand. J Muscle Res Cell Motil (2012) 0.87
Insights into human beta-cardiac myosin function from single molecule and single cell studies. J Cardiovasc Transl Res (2009) 0.85
Rigorous analysis of light diffraction ellipsometry by striated muscle fibers. Biophys J (1994) 0.84
Emergent systems energy laws for predicting myosin ensemble processivity. PLoS Comput Biol (2015) 0.83
Tracking actomyosin at fluorescence check points. Sci Rep (2013) 0.82
Actin-crosslinking protein regulation of filament movement in motility assays: a theoretical model. Biophys J (1994) 0.81
Velocity-dependent actomyosin ATPase cycle revealed by in vitro motility assay with kinetic analysis. Biophys J (2012) 0.79
Velocity of movement of actin filaments in in vitro motility assay. Measured by fluorescence correlation spectroscopy. Biophys J (1992) 0.79
How single molecule detection measures the dynamic actions of life. HFSP J (2007) 0.79
Ensemble velocity of non-processive molecular motors with multiple chemical states. Interface Focus (2014) 0.78
Random bursts determine dynamics of active filaments. Proc Natl Acad Sci U S A (2015) 0.78
Mechanosensitivity of the 2nd Kind: TGF-β Mechanism of Cell Sensing the Substrate Stiffness. PLoS One (2015) 0.77
The path to visualization of walking myosin V by high-speed atomic force microscopy. Biophys Rev (2014) 0.76
Actomyosin based contraction: one mechanokinetic model from single molecules to muscle? J Muscle Res Cell Motil (2016) 0.75
The double array of filaments in cross-striated muscle. J Biophys Biochem Cytol (1957) 24.69
Proposed mechanism of force generation in striated muscle. Nature (1971) 21.45
Structural changes in muscle during contraction; interference microscopy of living muscle fibres. Nature (1954) 17.88
Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation. Nature (1954) 17.75
The mechanism of muscular contraction. Science (1969) 14.47
Preparation of myosin and its subfragments from rabbit skeletal muscle. Methods Enzymol (1982) 6.29
Minimization of variation in the response to different proteins of the Coomassie blue G dye-binding assay for protein. Anal Biochem (1981) 5.95
Fluorescent actin filaments move on myosin fixed to a glass surface. Proc Natl Acad Sci U S A (1986) 5.67
Force measurements by micromanipulation of a single actin filament by glass needles. Nature (1988) 5.62
Myosin structure and function in cell motility. Annu Rev Cell Biol (1987) 4.33
Mechanism of actomyosin adenosine triphosphatase. Evidence that adenosine 5'-triphosphate hydrolysis can occur without dissociation of the actomyosin complex. Biochemistry (1979) 4.21
Energetics and mechanism of actomyosin adenosine triphosphatase. Biochemistry (1976) 3.97
Purification of muscle actin. Methods Cell Biol (1982) 3.87
Myosin subfragment-1 is sufficient to move actin filaments in vitro. Nature (1987) 3.44
Kinetics of acto-S1 interaction as a guide to a model for the crossbridge cycle. J Muscle Res Cell Motil (1984) 2.91
Polymerization of Acanthamoeba actin. Kinetics, thermodynamics, and co-polymerization with muscle actin. J Biol Chem (1976) 2.87
The initial phosphate burst in ATP hydrolysis by myosin and subfragment-1 as studied by a modified malachite green method for determination of inorganic phosphate. J Biochem (1986) 2.83
Sliding distance of actin filament induced by a myosin crossbridge during one ATP hydrolysis cycle. Nature (1985) 2.05
Myosin movement in vitro: a quantitative assay using oriented actin cables from Nitella. Methods Enzymol (1986) 1.70
Mechanism of interaction of Dictyostelium severin with actin filaments. J Cell Biol (1982) 1.69
The loose coupling mechanism in molecular machines of living cells. Adv Biophys (1986) 1.58
Movement of myosin fragments in vitro: domains involved in force production. Cell (1987) 1.39
Visualization of domains in native and nucleotide-trapped myosin heads by negative staining. J Muscle Res Cell Motil (1988) 1.00
Direct observation of molecular motility by light microscopy. Cell Motil Cytoskeleton (1988) 0.94
The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J Biol Chem (1971) 35.39
Single myosin molecule mechanics: piconewton forces and nanometre steps. Nature (1994) 13.73
Purification of muscle actin. Methods Enzymol (1982) 9.11
Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science (1987) 8.51
Myosin-V is a processive actin-based motor. Nature (1999) 7.13
Fluorescent actin filaments move on myosin fixed to a glass surface. Proc Natl Acad Sci U S A (1986) 5.67
Cytoskeletal elements of chick embryo fibroblasts revealed by detergent extraction. J Supramol Struct (1976) 5.42
Myosin-V stepping kinetics: a molecular model for processivity. Proc Natl Acad Sci U S A (2000) 5.03
Myosin structure and function in cell motility. Annu Rev Cell Biol (1987) 4.33
Nonmuscle contractile proteins: the role of actin and myosin in cell motility and shape determination. Annu Rev Biochem (1977) 4.25
Myosin VI is a processive motor with a large step size. Proc Natl Acad Sci U S A (2001) 3.95
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. Isolation and characterization of myosin from amoebae of Dictyostelium discoideum. J Mol Biol (1974) 3.91
Purification of muscle actin. Methods Cell Biol (1982) 3.87
Origin of proteins in sporulation. Annu Rev Biochem (1968) 3.86
Myosin step size. Estimation from slow sliding movement of actin over low densities of heavy meromyosin. J Mol Biol (1990) 3.80
Quantitative measurements of force and displacement using an optical trap. Biophys J (1996) 3.78
Movement of myosin-coated fluorescent beads on actin cables in vitro. Nature (1983) 3.76
The neck region of the myosin motor domain acts as a lever arm to generate movement. Proc Natl Acad Sci U S A (1996) 3.61
Assays for actin sliding movement over myosin-coated surfaces. Methods Enzymol (1991) 3.53
Myosin subfragment-1 is sufficient to move actin filaments in vitro. Nature (1987) 3.44
Single-molecule biomechanics with optical methods. Science (1999) 3.35
Control of nonmuscle myosins by phosphorylation. Annu Rev Biochem (1992) 3.34
Capping of surface receptors and concomitant cortical tension are generated by conventional myosin. Nature (1989) 3.24
Gene replacement in Dictyostelium: generation of myosin null mutants. EMBO J (1989) 3.04
Biochemical and structural studies of actomyosin-like proteins from non-muscle cells. II. Purification, properties, and membrane association of actin from amoebae of Dictyostelium discoideum. J Biol Chem (1974) 2.87
Cytochalasin B, its interaction with actin and actomyosin from muscle (cell movement-microfilaments-rabbit striated muscle). Proc Natl Acad Sci U S A (1972) 2.68
Cytochalasin inhibits the rate of elongation of actin filament fragments. J Cell Biol (1979) 2.67
Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo. Cell (1993) 2.61
Actin microheterogeneity in chick embryo fibroblasts. Proc Natl Acad Sci U S A (1977) 2.57
Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev (1996) 2.49
Calcium control of actin-activated myosin adenosine triphosphatase from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1976) 2.45
Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1. Nature (1993) 2.44
Biochemical and structural characterization of actin from Dictyostelium discoideum. J Biol Chem (1978) 2.39
Mechanism of action of cytochalasin: evidence that it binds to actin filament ends. J Cell Biol (1981) 2.36
Regulation of myosin self-assembly: phosphorylation of Dictyostelium heavy chain inhibits formation of thick filaments. Proc Natl Acad Sci U S A (1980) 2.35
Quantized velocities at low myosin densities in an in vitro motility assay. Nature (1991) 2.28
On the production of deletions in the chromosome of Escherichia coli. J Mol Biol (1970) 2.26
Biochemical studies of bacterial sporulation and germaination. VII. Protein turnover during sporulation of Bacillus subtilis. J Biol Chem (1968) 2.26
Visualization of actin fibers associated with the cell membrane in amoebae of Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 2.19
Regulation of skeletal muscle contraction. II. Structural studies of the interaction of the tropomyosin-troponin complex with actin. J Mol Biol (1972) 2.17
Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant. J Cell Biol (1990) 2.12
Role of highly conserved lysine 130 of myosin motor domain. In vivo and in vitro characterization of site specifically mutated myosin. J Biol Chem (1994) 2.11
Myosin dynamics in live Dictyostelium cells. Proc Natl Acad Sci U S A (1996) 2.10
Mechanism of K+-induced actin assembly. J Cell Biol (1982) 2.08
Biochemical studies of bacterial sporulation and germination. VI. Origin of spore core and coat proteins. J Biol Chem (1968) 2.06
Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1986) 2.05
In vitro assays of processive myosin motors. Methods (2000) 2.03
Towards a molecular understanding of cytokinesis. Trends Cell Biol (2000) 1.98
Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton. J Cell Biol (1996) 1.98
Chemoattractant-elicited increases in myosin phosphorylation in Dictyostelium. Cell (1985) 1.93
On the role of myosin-II in cytokinesis: division of Dictyostelium cells under adhesive and nonadhesive conditions. Mol Biol Cell (1997) 1.91
Biochemical studies of bacterial sporulation and germination. XII. A sulfonic acid as a major sulfur compound of Bacillus subtilis spores. J Bacteriol (1969) 1.89
Molecular evolution of the myosin family: relationships derived from comparisons of amino acid sequences. Proc Natl Acad Sci U S A (1993) 1.88
Detection of single-molecule interactions using correlated thermal diffusion. Proc Natl Acad Sci U S A (1997) 1.87
Biochemical studies on the mode of action of cytochalasin B. Cytochalasin B binding to red cell membrane in relation to glucose transport. J Biol Chem (1974) 1.86
ATP-dependent movement of myosin in vitro: characterization of a quantitative assay. J Cell Biol (1984) 1.84
Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. Proc Natl Acad Sci U S A (1996) 1.78
Structure of actin filament bundles from microvilli of sea urchin eggs. J Mol Biol (1979) 1.76
A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin. Cell (2000) 1.75
A functional recombinant myosin II lacking a regulatory light chain-binding site. Science (1993) 1.73
Myosin movement in vitro: a quantitative assay using oriented actin cables from Nitella. Methods Enzymol (1986) 1.70
Mechanism of interaction of Dictyostelium severin with actin filaments. J Cell Biol (1982) 1.69
Cloning and characterization of a nonmuscle myosin heavy chain cDNA. Proc Natl Acad Sci U S A (1985) 1.69
Spatial and temporal control of nonmuscle myosin localization: identification of a domain that is necessary for myosin filament disassembly in vivo. J Cell Biol (1991) 1.65
Movement of myosin-coated beads on oriented filaments reconstituted from purified actin. Nature (1985) 1.65
Light chain phosphorylation regulates the movement of smooth muscle myosin on actin filaments. J Cell Biol (1985) 1.63
The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility. Mol Biol Cell (1993) 1.61
A 40,000-dalton protein from Dictyostelium discoideum affects assembly properties of actin in a Ca2+-dependent manner. J Cell Biol (1982) 1.59
Enzymatic activities correlate with chimaeric substitutions at the actin-binding face of myosin. Nature (1994) 1.59
Multiple actin-based motor genes in Dictyostelium. Cell Regul (1989) 1.59
Detection of actin assembly by fluorescence energy transfer. J Cell Biol (1981) 1.58
Yeast actin filaments display ATP-dependent sliding movement over surfaces coated with rabbit muscle myosin. Proc Natl Acad Sci U S A (1992) 1.56
Regulation of cation transport in Saccharomyces cerevisiae by the salt tolerance gene HAL3. Mol Cell Biol (1995) 1.56
A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter. Mol Cell Biol (1999) 1.53
Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant. J Cell Biol (2000) 1.53
A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nat Cell Biol (2001) 1.52
Regulation of G2/M progression by the STE mitogen-activated protein kinase pathway in budding yeast filamentous growth. Mol Biol Cell (1999) 1.51
Myosin heavy chain phosphorylation sites regulate myosin localization during cytokinesis in live cells. Mol Biol Cell (1997) 1.50
Chemoattractant-elicited increases in Dictyostelium myosin phosphorylation are due to changes in myosin localization and increases in kinase activity. J Biol Chem (1987) 1.50
Monoclonal antibodies prepared against Dictyostelium actin: characterization and interactions with actin. J Cell Biol (1984) 1.46
Biochemical studies on the mode of action of cytochalasin B. Preparation of (3H)cytochalasin B and studies on its binding of cells. J Biol Chem (1974) 1.43
ATP-driven steady-state exchange of monomeric and filamentous actin from Dictyostelium discoideum. Proc Natl Acad Sci U S A (1980) 1.42
Movement of myosin fragments in vitro: domains involved in force production. Cell (1987) 1.39
Nucleation of polar actin filament assembly by a positively charged surface. J Cell Biol (1979) 1.39
Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression. J Biol Chem (2001) 1.38
Actin filaments undergo limited subunit exchange in physiological salt conditions. J Cell Biol (1982) 1.36
Myosin II localization during cytokinesis occurs by a mechanism that does not require its motor domain. Proc Natl Acad Sci U S A (1998) 1.35
Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft. Mol Biol Cell (1996) 1.34
Genetic analysis reveals that FLO11 upregulation and cell polarization independently regulate invasive growth in Saccharomyces cerevisiae. Genetics (2000) 1.33
Monoclonal antibodies against seven sites on the head and tail of Dictyostelium myosin. J Cell Biol (1985) 1.32
Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function. J Cell Biol (1987) 1.32
Characterization of single actin-myosin interactions. Biophys J (1995) 1.31
Cell cycle control of yeast filamentous growth. Curr Opin Microbiol (2001) 1.31
Supramolecular forms of actin from amoebae of Dictyostelium discoideum. J Biol Chem (1975) 1.31