Published in Pharmacogenomics J on April 05, 2011
The genetics of addiction-a translational perspective. Transl Psychiatry (2012) 1.30
Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis. J Abnorm Psychol (2015) 0.79
Identifying gene networks underlying the neurobiology of ethanol and alcoholism. Alcohol Res (2012) 0.78
Drosophila and Caenorhabditis elegans as Discovery Platforms for Genes Involved in Human Alcohol Use Disorder. Alcohol Clin Exp Res (2015) 0.77
Gene-based and pathway-based genome-wide association study of alcohol dependence. Shanghai Arch Psychiatry (2015) 0.75
Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. Prog Mol Biol Transl Sci (2015) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA. J Stud Alcohol (1994) 12.91
Pathway-based approaches for analysis of genomewide association studies. Am J Hum Genet (2007) 12.27
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature (2009) 8.12
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Genomewide association for schizophrenia in the CATIE study: results of stage 1. Mol Psychiatry (2008) 4.14
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet (2004) 3.91
Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol (2008) 3.13
GABA(A) receptor diversity and pharmacology. Cell Tissue Res (2006) 2.19
Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use. Biol Psychiatry (2007) 1.78
The role of glutamatergic neurotransmission in the pathophysiology of alcoholism. Annu Rev Med (1998) 1.72
Opioids and alcoholism. Physiol Behav (2004) 1.67
Polymorphisms of the glucocorticoid receptor gene and major depression. Biol Psychiatry (2006) 1.62
Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol Psychiatry (2006) 1.59
The temporal relationship of the onsets of alcohol dependence and major depression: using a genetically informative study design. Psychol Med (2006) 1.56
Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet B Neuropsychiatr Genet (2003) 1.47
Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior. Arch Gen Psychiatry (2008) 1.39
Up-regulation of NMDA receptor subunits in rat brain following chronic ethanol treatment. Brain Res Mol Brain Res (1998) 1.33
The Irish Affected Sib Pair Study of Alcohol Dependence: study methodology and validation of diagnosis by interview and family history. Alcohol Clin Exp Res (2005) 1.33
An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray. Eur J Hum Genet (2005) 1.27
Candidate genes for nicotine dependence via linkage, epistasis, and bioinformatics. Am J Med Genet B Neuropsychiatr Genet (2004) 1.21
Signaling cascades regulating NMDA receptor sensitivity to ethanol. Neuroscientist (2004) 1.20
Integrating domain knowledge with statistical and data mining methods for high-density genomic SNP disease association analysis. J Biomed Inform (2007) 1.16
Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior. Dialogues Clin Neurosci (2006) 1.15
A gene harvest revealing the archeology and complexity of human disease. Nat Genet (2007) 1.15
CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques. Arch Gen Psychiatry (2008) 1.09
Plasma cortisol levels following ethanol in sons of alcoholics and controls. Arch Gen Psychiatry (1987) 1.09
Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2004) 1.03
Corticotropin-releasing hormone (CRH) in psychiatry: from stress to psychopathology. Ann Med (2004) 1.00
D2 dopamine receptor and GABA(A) receptor beta3 subunit genes and alcoholism. Psychiatry Res (1998) 0.99
Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population. Mol Psychiatry (1999) 0.98
No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample. Am J Med Genet B Neuropsychiatr Genet (2005) 0.96
Evidence for a common biological basis of the Absorption trait, hallucinogen effects, and positive symptoms: epistasis between 5-HT2a and COMT polymorphisms. Am J Med Genet B Neuropsychiatr Genet (2005) 0.95
Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits. Biol Psychiatry (2003) 0.94
Association analysis of a regulatory variation of the serotonin transporter gene with severe alcohol dependence. Alcohol Clin Exp Res (1997) 0.92
Comparison of the role of dopamine, serotonin, and noradrenaline genes in ADHD, ODD and conduct disorder: multivariate regression analysis of 20 genes. Clin Genet (2000) 0.91
Adolescence, glucocorticoids and alcohol. Pharmacol Biochem Behav (2006) 0.90
Structural and functional modifications in glutamateric synapses following prolonged ethanol exposure. Alcohol Clin Exp Res (2006) 0.90
Hormone responses to social stress in abstinent alcohol-dependent subjects and social drinkers with no history of alcohol dependence. Alcohol Clin Exp Res (2005) 0.87
Hypothalamic-pituitary-adrenal system regulation in recently detoxified alcoholics is not altered by one week of treatment with acamprosate. Pharmacopsychiatry (2004) 0.83
GRIN1 locus may modify the susceptibility to seizures during alcohol withdrawal. Am J Med Genet B Neuropsychiatr Genet (2005) 0.83
Analysis of epistasis in linked regions in the Irish study of high-density schizophrenia families. Am J Med Genet (2001) 0.77
Dysregulation of hypothalamic-pituitary-adrenal axis function in depressed alcoholic patients. J Affect Disord (1982) 0.76
Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry (1994) 48.75
Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry (2000) 9.02
Childhood adversity and adult psychiatric disorder in the US National Comorbidity Survey. Psychol Med (1997) 5.53
A review and meta-analysis of the genetic epidemiology of anxiety disorders. Am J Psychiatry (2001) 4.55
What is a mental/psychiatric disorder? From DSM-IV to DSM-V. Psychol Med (2010) 4.33
Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet (2001) 3.73
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry (2007) 3.49
Genetic and environmental contributions to alcohol abuse and dependence in a population-based sample of male twins. Am J Psychiatry (1999) 3.38
The genetic epidemiology of smoking. Nicotine Tob Res (1999) 3.21
The power of the classical twin study to resolve variation in threshold traits. Behav Genet (1994) 2.97
Age at first drink and risk for alcoholism: a noncausal association. Alcohol Clin Exp Res (1999) 2.71
Replication of linkage studies of complex traits: an examination of variation in location estimates. Am J Hum Genet (1999) 2.50
Genetic epidemiology of binging and vomiting. Br J Psychiatry (1998) 2.41
Heritability of binge-eating and broadly defined bulimia nervosa. Biol Psychiatry (1998) 2.34
A whole genome association study of neuroticism using DNA pooling. Mol Psychiatry (2007) 2.30
Models for the joint effect of genotype and environment on liability to psychiatric illness. Am J Psychiatry (1986) 2.29
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry (2010) 2.21
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry (2012) 2.20
Joint linkage of multiple loci for a complex disorder. Am J Hum Genet (1993) 2.20
Models of comorbidity for multifactorial disorders. Am J Hum Genet (1995) 2.10
Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample. Mol Psychiatry (2009) 2.09
Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Mol Psychiatry (2008) 2.07
Depression and parental bonding: cause, consequence, or genetic covariance? Genet Epidemiol (1994) 2.05
Neuroticism, major depression and gender: a population-based twin study. Psychol Med (2002) 2.01
Latent class analysis of lifetime depressive symptoms in the national comorbidity survey. Am J Psychiatry (1998) 1.95
Identification of genetically mediated cortical networks: a multivariate study of pediatric twins and siblings. Cereb Cortex (2008) 1.89
Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families. Mol Psychiatry (1997) 1.87
The resolution of cultural and biological inheritance: informativeness of different relationships. Behav Genet (1985) 1.86
Assortative mating for major psychiatric diagnoses in two population-based samples. Psychol Med (1998) 1.80
Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. Mol Psychiatry (1999) 1.79
Major depressive disorder. Neuron (2000) 1.79
Anorexia nervosa and major depression: shared genetic and environmental risk factors. Am J Psychiatry (2000) 1.78
Symptoms of anxiety and symptoms of depression. Same genes, different environments? Arch Gen Psychiatry (1987) 1.75
Multivariate assessment of factors influencing illicit substance use in twins from female-female pairs. Am J Med Genet (2000) 1.74
Sex differences in the sources of genetic liability to alcohol abuse and dependence in a population-based sample of U.S. twins. Alcohol Clin Exp Res (1999) 1.71
Psychiatric 'diseases' versus behavioral disorders and degree of genetic influence. Psychol Med (2010) 1.69
Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III. Am J Hum Genet (2000) 1.68
Testing hypotheses about direction of causation using cross-sectional family data. Behav Genet (1993) 1.66
Dimensional representations of DSM-IV cluster B personality disorders in a population-based sample of Norwegian twins: a multivariate study. Psychol Med (2008) 1.64
Evidence for genetic influences on sleep disturbance and sleep pattern in twins. Sleep (1990) 1.63
Genetic heterogeneity, modifier genes, and quantitative phenotypes in psychiatric illness: searching for a framework. Mol Psychiatry (2005) 1.58
A multivariate genetic analysis of the use of tobacco, alcohol, and caffeine in a population based sample of male and female twins. Drug Alcohol Depend (1999) 1.57
Schizophrenia and schizophrenia-spectrum personality disorders in the first-degree relatives of children with schizophrenia: the UCLA family study. Arch Gen Psychiatry (2001) 1.57
Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes. Mol Psychiatry (2002) 1.56
A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22). Am J Med Genet (1996) 1.55
An empirical study of the classification of eating disorders. Am J Psychiatry (2000) 1.52
A model system for analysis of family resemblance in extended kinships of twins. Behav Genet (1994) 1.50
Twin studies of eating disorders: a review. Int J Eat Disord (2000) 1.50
Disentangling the causal inter-relationship between negative life events and depressive symptoms in women: a longitudinal twin study. Psychol Med (2012) 1.49
Genomewide linkage study in the Irish affected sib pair study of alcohol dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4. Mol Psychiatry (2006) 1.47
The dystrobrevin-binding protein 1 gene: features and networks. Mol Psychiatry (2008) 1.47
Anorexia nervosa and anorexic-like syndromes in a population-based female twin sample. Am J Psychiatry (1995) 1.46
Features of childhood sexual abuse and the development of psychiatric and substance use disorders. Br J Psychiatry (2001) 1.45
Genetic and environmental contributions to the relationship between education and anxiety disorders - a twin study. Acta Psychiatr Scand (2011) 1.45
A new test for linkage in the presence of locus heterogeneity. Am J Hum Genet (1992) 1.44
Genetics and developmental psychopathology: 1. Phenotypic assessment in the Virginia Twin Study of Adolescent Behavioral Development. J Child Psychol Psychiatry (1997) 1.43
Association between glutamic acid decarboxylase genes and anxiety disorders, major depression, and neuroticism. Mol Psychiatry (2006) 1.43
Sex-specific genetic influences on the comorbidity of alcoholism and major depression in a population-based sample of US twins. Arch Gen Psychiatry (2000) 1.43
Physical similarity and the equal-environment assumption in twin studies of psychiatric disorders. Behav Genet (1995) 1.38
Illicit drug use and abuse/dependence: modeling of two-stage variables using the CCC approach. Addict Behav (2005) 1.38
A nod factor binding lectin with apyrase activity from legume roots. Proc Natl Acad Sci U S A (1999) 1.35
Deconstructing major depression: a validation study of the DSM-IV symptomatic criteria. Psychol Med (2010) 1.34
Gender differences in binge-eating: a population-based twin study. Acta Psychiatr Scand (2003) 1.33
Linkage disequilibrium between two highly polymorphic microsatellites. Am J Hum Genet (1991) 1.32
The nosologic validity of paranoia (simple delusional disorder). A review. Arch Gen Psychiatry (1980) 1.30
Dimensions of delusional experience. Am J Psychiatry (1983) 1.30
Variants in the catechol-o-methyltransferase (COMT) gene are associated with schizophrenia in Irish high-density families. Mol Psychiatry (2004) 1.29
Interventionist causal models in psychiatry: repositioning the mind-body problem. Psychol Med (2008) 1.29
Identification of a high-risk haplotype for the dystrobrevin binding protein 1 (DTNBP1) gene in the Irish study of high-density schizophrenia families. Mol Psychiatry (2003) 1.28
Overview: a current perspective on twin studies of schizophrenia. Am J Psychiatry (1983) 1.28
Haplotypes of four novel single nucleotide polymorphisms in the nicotinic acetylcholine receptor beta2-subunit (CHRNB2) gene show no association with smoking initiation or nicotine dependence. Am J Med Genet (2000) 1.27
The pathoplasticity of dysphoric episodes: differential impact of stressful life events on the pattern of depressive symptom inter-correlations. Psychol Med (2011) 1.26
Multivariate genetic analysis of twin-family data on fears: Mx models. Behav Genet (1994) 1.22
FP-TDI SNP scoring by manual and statistical procedures: a study of error rates and types. Biotechniques (2003) 1.22
Ernst Rüdin (1874-1952) and his genealogic-demographic department in Munich (1917-1986): an introduction to their family studies of schizophrenia. Am J Med Genet (1996) 1.21
Symptoms of anxiety and depression in a volunteer twin population. The etiologic role of genetic and environmental factors. Arch Gen Psychiatry (1986) 1.20
The epidemiology and classification of bulimia nervosa. Psychol Med (1998) 1.20
Linkage analysis of smoking initiation and quantity in Dutch sibling pairs. Pharmacogenomics J (2004) 1.20
The genetic epidemiology of parental discipline. Psychol Med (2000) 1.19
Reliability of a lifetime history of major depression: implications for heritability and co-morbidity. Psychol Med (1998) 1.18
Interleukin 3 and schizophrenia: the impact of sex and family history. Mol Psychiatry (2006) 1.17
The relationship between social support and major depression: cross-sectional, longitudinal, and genetic perspectives. J Nerv Ment Dis (2000) 1.16
Associations between marital status and alcohol consumption in a longitudinal study of female twins. J Stud Alcohol (2001) 1.16
A twin study of generalized anxiety disorder and major depression. Psychol Med (1995) 1.15
An independent analysis of the Copenhagen sample of the Danish adoption study of schizophrenia. II. The relationship between schizotypal personality disorder and schizophrenia. Arch Gen Psychiatry (1981) 1.14
A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia. Mol Psychiatry (2008) 1.14
Accuracies and inaccuracies of the family history method: a multivariate approach. Acta Psychiatr Scand (1996) 1.13
Relationship between positive and negative symptoms of schizophrenia and schizotypal symptoms in nonpsychotic relatives. Arch Gen Psychiatry (2001) 1.13
Fatigue in a community sample of twins. Psychol Med (2003) 1.13
A schizophrenia locus may be located in region 10p15-p11. Am J Med Genet (1998) 1.12
The effects of anxiety, substance use and conduct disorders on risk of major depressive disorder. Psychol Med (2003) 1.12
Typology of common psychiatric syndromes. An empirical study. Br J Psychiatry (1998) 1.12
A population-based twin study of generalized anxiety disorder in men and women. J Nerv Ment Dis (2001) 1.11
Genetic case-control association studies in neuropsychiatry. Arch Gen Psychiatry (2001) 1.11