Published in BMC Pharmacol on April 07, 2011
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Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cell Mol Neurobiol (2006) 1.09
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Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2. J Neurochem (2005) 1.00
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Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Am J Psychiatry (2007) 2.84
Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. Am J Hum Genet (2003) 2.55
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet (2010) 2.46
A human serotonin transporter mutation causes constitutive activation of transport activity. Mol Pharmacol (2003) 2.15
Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33. Am J Psychiatry (2007) 1.85
Monoamine oxidase A gene promoter variation and rearing experience influences aggressive behavior in rhesus monkeys. Biol Psychiatry (2005) 1.81
Caloric restriction experience reprograms stress and orexigenic pathways and promotes binge eating. J Neurosci (2010) 1.77
Contribution of common genetic variants to antidepressant response. Biol Psychiatry (2012) 1.73
Epigenetic influences on brain development and plasticity. Curr Opin Neurobiol (2009) 1.72
Gene expression and genetic variation data implicate PCLO in bipolar disorder. Biol Psychiatry (2010) 1.70
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet (2013) 1.68
Gene dose-dependent alterations in extraneuronal serotonin but not dopamine in mice with reduced serotonin transporter expression. J Neurosci Methods (2004) 1.59
Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biol Psychiatry (2003) 1.58
Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans. J Clin Invest (2008) 1.57
How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology (2008) 1.56
Further development of YBOCS dimensions in the OCD Collaborative Genetics study: symptoms vs. categories. Psychiatry Res (2008) 1.54
Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice. Cereb Cortex (2009) 1.48
Psychiatric symptoms associated with focal hand dystonia. Mov Disord (2010) 1.47
Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behav Res Ther (2006) 1.41
Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology (2004) 1.41
A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder. Hum Mol Genet (2007) 1.39
Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology (2002) 1.39
Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology (2003) 1.36
Obsessive-compulsive disorder symptom dimensions show specific relationships to psychiatric comorbidity. Psychiatry Res (2005) 1.31
Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice. Am J Physiol Gastrointest Liver Physiol (2008) 1.31
Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation. J Neurochem (2009) 1.28
Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behav Pharmacol (2008) 1.23
Exaggerated adrenomedullary response to immobilization in mice with targeted disruption of the serotonin transporter gene. Endocrinology (2002) 1.23
Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study. Biol Psychiatry (2006) 1.22
Ethanol inhibits clearance of brain serotonin by a serotonin transporter-independent mechanism. J Neurosci (2006) 1.21
Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology (2005) 1.20
Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndrome. Brain (2012) 1.19
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Analyzing grooming microstructure in neurobehavioral experiments. Nat Protoc (2007) 1.18
Ethanol-related behaviors in serotonin transporter knockout mice. Alcohol Clin Exp Res (2006) 1.18
A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder. Arch Gen Psychiatry (2009) 1.16
Involvement of insula and cingulate cortices in control and suppression of natural urges. Cereb Cortex (2008) 1.14
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees. Biol Psychiatry (2004) 1.13
Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice. Behav Genet (2007) 1.10
Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cell Mol Neurobiol (2006) 1.09
Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter. Am J Physiol Gastrointest Liver Physiol (2002) 1.08
Reduced aggression in mice lacking the serotonin transporter. Psychopharmacology (Berl) (2002) 1.08
The OCD collaborative genetics study: methods and sample description. Am J Med Genet B Neuropsychiatr Genet (2006) 1.08
Serotonin uptake into dopamine neurons via dopamine transporters: a compensatory alternative. Brain Res (2002) 1.08
Developmental disruption of serotonin transporter function impairs cerebral responses to whisker stimulation in mice. Proc Natl Acad Sci U S A (2005) 1.08
A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder. Neuropsychopharmacology (2007) 1.07
Brain region-specific alterations of 5-HT2A and 5-HT2C receptors in serotonin transporter knockout mice. J Neurochem (2003) 1.07
Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. J Neurochem (2003) 1.07
Absence of thermal hyperalgesia in serotonin transporter-deficient mice. J Neurosci (2003) 1.05
Vulnerability to mild predator stress in serotonin transporter knockout mice. Behav Brain Res (2006) 1.05
5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter. Psychopharmacology (Berl) (2005) 1.03
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice. Psychopharmacology (Berl) (2008) 1.02
The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction. Pflugers Arch (2013) 1.02
Exploration of anxiety sensitivity and distress tolerance as vulnerability factors for hoarding behaviors. Depress Anxiety (2009) 1.01
Cooperation between mast cells and neurons is essential for antigen-mediated bronchoconstriction. J Immunol (2009) 1.00
A systematic eQTL study of cis-trans epistasis in 210 HapMap individuals. Eur J Hum Genet (2011) 1.00
Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. Eur J Pharmacol (2007) 1.00
Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice. Neuropharmacology (2007) 0.98
The serotonin 5-HT(2A) receptor agonist TCB-2: a behavioral and neurophysiological analysis. Psychopharmacology (Berl) (2009) 0.98
Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling. Mol Cell Neurosci (2007) 0.98
Do traumatic events influence the clinical expression of compulsive hoarding? Behav Res Ther (2007) 0.98
Loss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. J Neurosci Res (2005) 0.97
Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder. Psychiatr Genet (2008) 0.97
Genetics of early-onset obsessive-compulsive disorder. Eur Child Adolesc Psychiatry (2010) 0.97
The developing use of heterozygous mutant mouse models in brain monoamine transporter research. Trends Pharmacol Sci (2007) 0.96
miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells. Int J Neuropsychopharmacol (2012) 0.94
A pharmacological analysis of mice with a targeted disruption of the serotonin transporter. Psychopharmacology (Berl) (2007) 0.94
An investigation of traumatic life events and obsessive-compulsive disorder. Behav Res Ther (2006) 0.94
Anxiety and affective disorder comorbidity related to serotonin and other neurotransmitter systems: obsessive-compulsive disorder as an example of overlapping clinical and genetic heterogeneity. Philos Trans R Soc Lond B Biol Sci (2013) 0.94
Diagnostic interview assessed neuropsychiatric disorder comorbidity in 334 individuals with obsessive-compulsive disorder. Depress Anxiety (2004) 0.93
Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. J Neurosci (2004) 0.93
Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice. Brain Res (2007) 0.93
Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 0.93
Continuous nicotine administration produces selective, age-dependent structural alteration of pyramidal neurons from prelimbic cortex. Synapse (2008) 0.92
SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder. Psychiatr Genet (2008) 0.91
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Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters. Synapse (2005) 0.90
Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry (2014) 0.90
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17beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotection. FASEB J (2003) 0.89
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