Published in Anemia on October 13, 2010
A Retrospective Analysis of the Significance of Haemoglobin SS and SC in Disease Outcome in Patients With Sickle Cell Disease and Dengue Fever. EBioMedicine (2015) 0.88
Elevated hypercoagulability markers in hemoglobin SC disease. Haematologica (2015) 0.80
Differential time-dependent volumetric and surface area changes and delayed induction of new permeation pathways in P. falciparum-infected hemoglobinopathic erythrocytes. Cell Microbiol (2016) 0.78
Human Parvovirus B19 in Children with Sickle Cell Disease; Poking the Spleen. Oman Med J (2017) 0.75
Sickle cell anemia a molecular disease. Science (1949) 21.90
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med (2002) 7.59
The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. JAMA (2005) 6.49
Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature (1957) 6.47
Sickle-cell disease. Lancet (2004) 4.76
The function of calcium in the potassium permeability of human erythrocytes. Biochim Biophys Acta (1958) 3.81
Human beta-globin messenger RNA. III. Nucleotide sequences derived from complementary DNA. J Biol Chem (1977) 3.55
The inherited diseases of hemoglobin are an emerging global health burden. Blood (2010) 3.48
Management of sickle cell disease. N Engl J Med (1999) 2.73
Hemoglobin S gelation and sickle cell disease. Blood (1987) 2.41
Sickle-cell disease. Lancet (1997) 2.24
Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity. N Engl J Med (1980) 2.14
Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology. Blood (1991) 1.97
The paradox of hemoglobin SC disease. Blood Rev (2003) 1.75
Discovering the genetics underlying foetal haemoglobin production in adults. Br J Haematol (2008) 1.70
Sickle cell disease vasculopathy: a state of nitric oxide resistance. Free Radic Biol Med (2008) 1.69
Mapping the prevalence of sickle cell and beta thalassaemia in England: estimating and validating ethnic-specific rates. Br J Haematol (1999) 1.67
Regulation of erythrocyte cation and water content in sickle cell anemia. Science (1986) 1.65
Ion transport pathology in the mechanism of sickle cell dehydration. Physiol Rev (2005) 1.64
Adhesion of normal and sickle erythrocytes to endothelial monolayer cultures. Blood (1979) 1.58
Genetic etiologies for phenotypic diversity in sickle cell anemia. ScientificWorldJournal (2009) 1.49
Role of erythrocyte phosphatidylserine in sickle red cell-endothelial adhesion. Blood (2002) 1.47
Evidence for a direct reticulocyte origin of dense red cells in sickle cell anemia. J Clin Invest (1991) 1.38
Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. Am J Hematol (2010) 1.34
Volume-dependent and NEM-stimulated K+,Cl- transport is elevated in oxygenated SS, SC and CC human red cells. FEBS Lett (1986) 1.32
Molecular and cellular pathogenesis of hemoglobin SC disease. Proc Natl Acad Sci U S A (1982) 1.32
Cation transport and volume regulation in sickle red blood cells. Am J Physiol (1993) 1.22
Deoxygenation permeabilizes sickle cell anaemia red cells to magnesium and reverses its gradient in the dense cells. J Physiol (1990) 1.21
SC erythrocytes have an abnormally high intracellular hemoglobin concentration. Pathophysiological consequences. J Clin Invest (1982) 1.18
Evidence for the presence of volume-sensitive KCl transport in 'young' human red cells. Biochim Biophys Acta (1986) 1.17
Heme induces endothelial tissue factor expression: potential role in hemostatic activation in patients with hemolytic anemia. J Thromb Haemost (2008) 1.14
Oxygen-sensitive membrane transporters in vertebrate red cells. J Exp Biol (2000) 1.13
The variable expression of sickle cell disease is genetically determined. Semin Hematol (1990) 1.12
Ca2+ sensitivity of phospholipid scrambling in human red cell ghosts. Cell Calcium (1999) 1.12
Stochastic nature and red cell population distribution of the sickling-induced Ca2+ permeability. J Clin Invest (1997) 1.10
Differential oxygen sensitivity of the K+-Cl- cotransporter in normal and sickle human red blood cells. J Physiol (1998) 1.09
A comparison of erythrocyte characteristics in sickle cell syndromes in Jamaica. Br J Haematol (1972) 1.09
Association between morphologic distortion of sickle cells and deoxygenation-induced cation permeability increase. Blood (1986) 1.08
Ca2+ permeability in deoxygenated sickle cells. Blood (1990) 1.04
Microvascular endothelial cells express a phosphatidylserine receptor: a functionally active receptor for phosphatidylserine-positive erythrocytes. Blood (2007) 1.03
Peptides based on alphaV-binding domains of erythrocyte ICAM-4 inhibit sickle red cell-endothelial interactions and vaso-occlusion in the microcirculation. Am J Physiol Cell Physiol (2006) 1.00
Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytes. Blood (1992) 0.99
The unique red cell heterogeneity of SC disease: crystal formation, dense reticulocytes, and unusual morphology. Blood (1991) 0.96
The distinct pathobiology of sickle cell-hemoglobin C disease. Therapeutic implications. Hematol Oncol Clin North Am (1991) 0.94
The effect of deoxygenation on whole-cell conductance of red blood cells from healthy individuals and patients with sickle cell disease. Blood (2006) 0.94
Membrane transport in sickle cell disease. Blood Cells Mol Dis (2002) 0.93
Simultaneous determination of low free Mg2+ and pH in human sickle cells using 31P NMR spectroscopy. J Biol Chem (2002) 0.92
KCl cotransport activity in light versus dense transferrin receptor-positive sickle reticulocytes. J Clin Invest (1995) 0.91
Red cell membrane lipids in hemoglobinopathies. Curr Mol Med (2008) 0.90
Deoxygenation-induced non-electrolyte pathway in red cells from sickle cell patients. Cell Physiol Biochem (2007) 0.88
Ionic strength dependence of the polymer solubilities of deoxyhemoglobin S + C and S + A mixtures. Blood (1986) 0.84
The xerocytosis of Hb SC disease. Blood (1987) 0.82
Novel permeability characteristics of red blood cells from sickle cell patients heterozygous for HbS and HbC (HbSC genotype). Blood Cells Mol Dis (2010) 0.82
O2 dependence of K+ transport in sickle cells: the effect of different cell populations and the substituted benzaldehyde 12C79. FASEB J (2001) 0.82
Dehydration of transferrin receptor-positive sickle reticulocytes during continuous or cyclic deoxygenation: role of KCl cotransport and extracellular calcium. Blood (1996) 0.81
Non-electrolyte permeability of deoxygenated sickle cells compared. Blood Cells Mol Dis (2008) 0.78
Phylogenetic diversity of the Rickettsiae. J Bacteriol (1989) 8.48
Structure of the MscL homolog from Mycobacterium tuberculosis: a gated mechanosensitive ion channel. Science (1998) 7.51
Separation of viable Rickettsia typhi from yolk sac and L cell host components by renografin density gradient centrifugation. Appl Microbiol (1975) 6.55
A common origin of rickettsiae and certain plant pathogens. Science (1985) 6.07
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science (1996) 4.47
Structure of the reaction center from Rhodobacter sphaeroides R-26: the cofactors. Proc Natl Acad Sci U S A (1987) 4.44
Growth and physiology of rickettsiae. Bacteriol Rev (1973) 4.04
Structure of the reaction center from Rhodobacter sphaeroides R-26: the protein subunits. Proc Natl Acad Sci U S A (1987) 3.91
Stapled haemorrhoidopexy: a consensus position paper by an international working party - indications, contra-indications and technique. Colorectal Dis (2003) 3.85
Crystallographic structure of the nitrogenase iron protein from Azotobacter vinelandii. Science (1992) 3.58
Refined crystal structure of carboxypeptidase A at 1.54 A resolution. J Mol Biol (1983) 3.56
Gastroduodenal dysfunction and bacterial colonisation of the ventilated lung. Lancet (1993) 3.47
Lack of deoxyribonucleic acid homology between species of the genus Chlamydia. J Bacteriol (1968) 3.36
Light-induced structural changes in photosynthetic reaction center: implications for mechanism of electron-proton transfer. Science (1997) 3.30
Structure of ADP x AIF4(-)-stabilized nitrogenase complex and its implications for signal transduction. Nature (1997) 3.26
Heparin structure and interactions with basic fibroblast growth factor. Science (1996) 3.00
Tumours of the soft (mesenchymal) tissues. Bull World Health Organ (1974) 2.85
An inward-facing conformation of a putative metal-chelate-type ABC transporter. Science (2006) 2.80
Global distribution of the CCR5 gene 32-basepair deletion. Nat Genet (1997) 2.77
Structural models for the metal centers in the nitrogenase molybdenum-iron protein. Science (1992) 2.72
Transaminase activity and other enzymatic reactions involving pyruvate and glutamate in Chlamydia (psittacosis-trachoma group). J Bacteriol (1967) 2.67
Structure of the Escherichia coli fumarate reductase respiratory complex. Science (1999) 2.59
Structure of a hyperthermophilic tungstopterin enzyme, aldehyde ferredoxin oxidoreductase. Science (1995) 2.54
The biology of rickettsiae. Annu Rev Microbiol (1982) 2.49
Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO J (1995) 2.38
Crystal structure of DMSO reductase: redox-linked changes in molybdopterin coordination. Science (1996) 2.35
Inhibition of the calcium-induced increase in the potassium permeability of human red blood cells by quinine. J Physiol (1975) 2.35
Redox-dependent structural changes in the nitrogenase P-cluster. Biochemistry (1997) 2.34
Three-dimensional structures of acidic and basic fibroblast growth factors. Science (1991) 2.26
Metabolism of Rickettsia typhi and Rickettsia akari in irradiated L cells. Infect Immun (1972) 2.23
Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA. J Cell Biol (1999) 2.22
Structural homology of reaction centers from Rhodopseudomonas sphaeroides and Rhodopseudomonas viridis as determined by x-ray diffraction. Proc Natl Acad Sci U S A (1986) 2.16
Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase. Cell (1997) 2.12
Characterization of the Madrid E strain of Rickettsia prowazekii purified by renografin density gradient centrifugation. Infect Immun (1977) 2.12
X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus. Protein Sci (1992) 2.11
Molybdenum-cofactor-containing enzymes: structure and mechanism. Annu Rev Biochem (1997) 2.06
A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA. Science (1998) 2.05
The efflux of magnesium from single crustacean muscle fibres. J Physiol (1972) 2.02
Tumours of the skin. Bull World Health Organ (1974) 2.01
Transport of diverse substrates into malaria-infected erythrocytes via a pathway showing functional characteristics of a chloride channel. J Biol Chem (1994) 2.00
DNA base composition of rickettsiae. Science (1973) 1.95
Expression of murine H-2Kb histocompatibility antigen in cells transformed with cloned H-2 genes. Nature (1982) 1.91
Binding of tritiated digoxin to human red cell ghosts. Nature (1969) 1.89
Women's lives and sex: implications for AIDS prevention. Cult Med Psychiatry (1993) 1.87
Structure of the reaction center from Rhodobacter sphaeroides R-26: protein-cofactor (quinones and Fe2+) interactions. Proc Natl Acad Sci U S A (1988) 1.87
Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states. Biochemistry (2000) 1.87
Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: symmetry relations and sequence comparisons between different species. Proc Natl Acad Sci U S A (1988) 1.86
Role of exogenous adenosine triphosphate in catabolic and synthetic activities of Chlamydia psittaci. J Bacteriol (1969) 1.86
Structure of the reaction center from Rhodobacter sphaeroides R-26: membrane-protein interactions. Proc Natl Acad Sci U S A (1987) 1.84
A patient education program is cost-effective for preventing failure of endoscopic procedures in a gastroenterology department. Am J Gastroenterol (2001) 1.81
Pathophysiologic basis of contrast enhancement in breast tumors. J Magn Reson Imaging (1999) 1.81
Energy metabolism of Rickettsia typhi: pools of adenine nucleotides and energy charge in the presence and absence of glutamate. J Bacteriol (1978) 1.81
Chloride-activated passive potassium transport in human erythrocytes. Proc Natl Acad Sci U S A (1980) 1.77
Suramin: a potent ATPase inhibitor which acts on the inside surface of the sodium pump. Biochim Biophys Acta (1973) 1.76
Crystallographic structure and functional implications of the nitrogenase molybdenum-iron protein from azotobacter vinelandii. Nature (1992) 1.75
Efficacy and safety of sodium phosphate tablets compared with PEG solution in colon cleansing: two identically designed, randomized, controlled, parallel group, multicenter phase III trials. Gastrointest Endosc (2001) 1.75
The nitrogenase FeMo-cofactor and P-cluster pair: 2.2 A resolution structures. Science (1993) 1.74
Structural basis for G.C recognition in the DNA minor groove. Nat Struct Biol (1998) 1.74
Biochemical characteristics of typhus group rickettsiae with special attention to the Rickettsia prowazekii strains isolated from flying squirrels. Infect Immun (1978) 1.71
Fractal surfaces of proteins. Science (1985) 1.69
Experimental evaluation of the effective dielectric constant of proteins. J Mol Biol (1980) 1.68
Passive potassium transport in low potassium sheep red cells: dependence upon cell volume and chloride. J Physiol (1981) 1.66
T-cell-derived lymphokines that induce IgM and IgG secretion in activated murine B cells. Immunol Rev (1984) 1.65
A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila. EMBO J (1996) 1.64
Refined crystal structure of the potato inhibitor complex of carboxypeptidase A at 2.5 A resolution. J Mol Biol (1982) 1.61
Response of mice to injection of ribosomal fraction from group B Neisseria meningitidis. Infect Immun (1972) 1.60
Biphasic culture system for rapid Campylobacter cultivation. Appl Environ Microbiol (1983) 1.60
Structure of the reaction center from Rhodobacter sphaeroides R-26 and 2.4.1: protein-cofactor (bacteriochlorophyll, bacteriopheophytin, and carotenoid) interactions. Proc Natl Acad Sci U S A (1988) 1.58
Vole agent identified as a strain of the trench fever rickettsia, Rochalimaea quintana. Infect Immun (1978) 1.54
Metabolism of Richettsia tsutsugamushi and Rickettsia rickettsi in irradiated host cells. Infect Immun (1973) 1.54
Worldwide distribution of a common methylenetetrahydrofolate reductase mutation. Am J Hum Genet (1998) 1.53
Genetic basis of hemolytic anemia caused by pyrimidine 5' nucleotidase deficiency. Blood (2001) 1.52
Enzymatic activities of cell-free extracts of Rickettsia typhi. Infect Immun (1976) 1.50
FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group. Br J Haematol (2000) 1.50
Anion-dependent cation transport in erythrocytes. Philos Trans R Soc Lond B Biol Sci (1982) 1.47
Structure of a photoactive rhodium complex intercalated into DNA. Nat Struct Biol (2000) 1.47
Glutamate catabolism of Rickettsia rickettsi and factors affecting retention of metabolic activity. J Bacteriol (1968) 1.46
Improved serodiagnosis of Salmonella enteric fevers by an enzyme-linked immunosorbent assay. J Clin Microbiol (1981) 1.46
Exchange of partners in glucagon receptor-adenylate cyclase complexes. Physical evidence for the independent, mobile receptor model. Biochim Biophys Acta (1977) 1.46
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells. J Physiol (2000) 1.46
Nitrogenase: a nucleotide-dependent molecular switch. Annu Rev Biochem (1994) 1.45
Leukocyte intracellular pH and Na/H antiporter activity in uraemia and type I diabetes mellitus. Nephrol Dial Transplant (1991) 1.44
Short-term outcomes of laparoscopic total mesorectal excision following neoadjuvant chemoradiotherapy. Surg Endosc (2009) 1.44
Human complement factor H deficiency associated with hemolytic uremic syndrome. J Am Soc Nephrol (1998) 1.43
Homeostasis of intracellular Ca2+ in equine chondrocytes: response to hypotonic shock. Equine Vet J (2003) 1.43
Molecular size of the tetrodotoxin binding site estimated by irradiation inactivation. Nat New Biol (1973) 1.42
Minisatellite mutational processes reduce F(st) estimates. Hum Genet (1999) 1.41
Amino acid transport in human and in sheep erythrocytes. Proc R Soc Lond B Biol Sci (1980) 1.41
Gastroduodenal dysfunction as a cause of gastric bacterial overgrowth in patients undergoing mechanical ventilation of the lungs. Br J Anaesth (1992) 1.40
A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila. Biochemistry (2000) 1.40
Observations on guinea pig inclusion conjunctivitis agent. J Infect Dis (1966) 1.39
Stimulation of the potassium transport system in low potassium type sheep red cells by a specific antigen antibody reaction. Nature (1969) 1.39
X-ray crystal structure of the nitrogenase molybdenum-iron protein from Clostridium pasteurianum at 3.0-A resolution. Biochemistry (1993) 1.37
Staphylococcal pneumonia in ventilated patients: a twelve-month review of cases in an intensive care unit. J Hosp Infect (1993) 1.37
The acceptability of the female condom: perspectives of family planning providers in New York City, South Africa, and Nigeria. J Urban Health (2001) 1.36
'Feeling the pressure': structural insights into a gated mechanosensitive channel. Curr Opin Struct Biol (1999) 1.35
Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science (1995) 1.34
A structural and immunological comparison of rickettsial HSP60 antigens with those of other species. Ann N Y Acad Sci (1990) 1.33