Published in Science on April 15, 2011
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Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori. Nature (2012) 1.08
The formate channel FocA exports the products of mixed-acid fermentation. Proc Natl Acad Sci U S A (2012) 1.05
Structural and functional characterization of the nitrite channel NirC from Salmonella typhimurium. Proc Natl Acad Sci U S A (2012) 0.99
Coordination of FocA and pyruvate formate-lyase synthesis in Escherichia coli demonstrates preferential translocation of formate over other mixed-acid fermentation products. J Bacteriol (2013) 0.91
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Ion selectivity and gating mechanisms of FNT channels. Curr Opin Struct Biol (2013) 0.81
Physiological and biochemical characterization of AnNitA, the Aspergillus nidulans high-affinity nitrite transporter. Eukaryot Cell (2011) 0.81
Exploring the pH-dependent substrate transport mechanism of FocA using molecular dynamics simulation. Biophys J (2013) 0.77
Organic Acid Excretion in Penicillium ochrochloron Increases with Ambient pH. Front Microbiol (2012) 0.77
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The glycyl-radical enzyme 2-ketobutyrate formate-lyase, TdcE, interacts specifically with the formate-translocating FNT-channel protein FocA. Biochem Biophys Rep (2016) 0.75
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Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med (2009) 3.97
TGM6 identified as a novel causative gene of spinocerebellar ataxias using exome sequencing. Brain (2010) 3.66
Structural basis of biological nitrogen fixation. Philos Trans A Math Phys Eng Sci (2005) 3.28
Evidence for interstitial carbon in nitrogenase FeMo cofactor. Science (2011) 3.16
Crystal structure of the archaeal ammonium transporter Amt-1 from Archaeoglobus fulgidus. Proc Natl Acad Sci U S A (2005) 2.49
FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis. Cell Res (2008) 2.33
T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction. Nature (2011) 2.26
Structure of a cofactor-deficient nitrogenase MoFe protein. Science (2002) 1.91
Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia. Blood (2010) 1.86
Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome. Blood (2009) 1.70
Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner. Blood (2011) 1.70
The role of human papillomavirus in the increased incidence of base of tongue cancer. Int J Cancer (2010) 1.69
Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study. J Biomed Opt (2007) 1.51
2-deoxy-D-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer. Free Radic Biol Med (2007) 1.40
Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death. Mol Cell Biol (2005) 1.38
Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system. Stroke (2009) 1.31
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase. Mol Biol Cell (2007) 1.30
Gene-expression profiling identifies distinct subclasses of core binding factor acute myeloid leukemia. Blood (2007) 1.28
Screening patients with diabetes mellitus for tuberculosis in China. Trop Med Int Health (2012) 1.27
Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG). Blood (2012) 1.25
The unprecedented nos gene cluster of Wolinella succinogenes encodes a novel respiratory electron transfer pathway to cytochrome c nitrous oxide reductase. FEBS Lett (2004) 1.25
Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway. Cancer Res (2009) 1.24
FAO/INFOODS food composition database for biodiversity. Food Chem (2012) 1.23
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. Am J Physiol Renal Physiol (2006) 1.22
Requirement and functional redundancy of Ib subgroup bHLH proteins for iron deficiency responses and uptake in Arabidopsis thaliana. Mol Plant (2012) 1.22
NEDD9 is a positive regulator of epithelial-mesenchymal transition and promotes invasion in aggressive breast cancer. PLoS One (2011) 1.19
Genetic correction of β-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice. Cell Res (2012) 1.18
Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1. Cell Rep (2013) 1.18
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew Chem Int Ed Engl (2013) 1.16
Human papillomavirus and survival in patients with base of tongue cancer. Int J Cancer (2010) 1.16
Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions. Blood (2013) 1.15
Genome-wide survey of V-ATPase genes in Drosophila reveals a conserved renal phenotype for lethal alleles. Physiol Genomics (2005) 1.15
Corosolic acid induces apoptosis through mitochondrial pathway and caspase activation in human cervix adenocarcinoma HeLa cells. Cancer Lett (2009) 1.13
Cellulose synthase INTERACTIVE3 regulates cellulose biosynthesis in both a microtubule-dependent and microtubule-independent manner in Arabidopsis. Plant Cell (2013) 1.13
N2O binding at a [4Cu:2S] copper-sulphur cluster in nitrous oxide reductase. Nature (2011) 1.12
Molecular and biochemical characterization of the Fe(III) chelate reductase gene family in Arabidopsis thaliana. Plant Cell Physiol (2005) 1.09
Prepregnancy body mass index, gestational weight gain, and pregnancy outcomes in China. Int J Gynaecol Obstet (2009) 1.08
Association of the frequency of peripheral natural killer T cells with nonalcoholic fatty liver disease. World J Gastroenterol (2007) 1.07
Baculoviral vector-mediated transient and stable transgene expression in human embryonic stem cells. Stem Cells (2007) 1.07
The ecology of medical care in Beijing. PLoS One (2013) 1.07
Transcriptome and gene expression analysis of the rice leaf folder, Cnaphalocrosis medinalis. PLoS One (2012) 1.07
Pore mutations in ammonium transporter AMT1 with increased electrogenic ammonium transport activity. J Biol Chem (2009) 1.06
Dramatic modulation of electron transfer in protein complexes by crosslinking. Nat Struct Biol (2002) 1.06
The Amt/Mep/Rh family of ammonium transport proteins. Mol Membr Biol (2007) 1.05
The formate channel FocA exports the products of mixed-acid fermentation. Proc Natl Acad Sci U S A (2012) 1.05
Binding and reduction of sulfite by cytochrome c nitrite reductase. Biochemistry (2008) 1.04
Biochemical and structural characterization of the cross-linked complex of nitrogenase: comparison to the ADP-AlF4(-)-stabilized structure. Biochemistry (2002) 1.03
Prognostic impact of minimal residual disease in CBFB-MYH11-positive acute myeloid leukemia. J Clin Oncol (2010) 1.03
Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection. Mol Cancer (2012) 1.03
Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice. Mol Cell Biol (2009) 1.02
Co-overexpression FIT with AtbHLH38 or AtbHLH39 in Arabidopsis-enhanced cadmium tolerance via increased cadmium sequestration in roots and improved iron homeostasis of shoots. Plant Physiol (2011) 1.02
The formate/nitrite transporter family of anion channels. Biol Chem (2013) 1.02
The Populus class III HD ZIP, popREVOLUTA, influences cambium initiation and patterning of woody stems. Plant Physiol (2010) 1.01
Clinical implications for girdin protein expression in breast cancer. Cancer Invest (2011) 1.01
A real-world study of patients with type 2 diabetes initiating basal insulins via disposable pens. Adv Ther (2011) 1.01
Structure of the non-redox-active tungsten/[4Fe:4S] enzyme acetylene hydratase. Proc Natl Acad Sci U S A (2007) 1.01
Myomectomy during cesarean section. Acta Obstet Gynecol Scand (2009) 1.01
Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia. PLoS One (2013) 1.00
Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generation. Cancer Res (2013) 0.99
Functional role of TRPV4-KCa2.3 signaling in vascular endothelial cells in normal and streptozotocin-induced diabetic rats. Hypertension (2013) 0.99
High resolution crystal structures of the wild type and Cys-55-->Ser and Cys-59-->Ser variants of the thioredoxin-like [2Fe-2S] ferredoxin from Aquifex aeolicus. J Biol Chem (2002) 0.99
Structural and functional characterization of the nitrite channel NirC from Salmonella typhimurium. Proc Natl Acad Sci U S A (2012) 0.99
Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm. J Clin Invest (2014) 0.99
ClpC1, an ATP-dependent Clp protease in plastids, is involved in iron homeostasis in Arabidopsis leaves. Ann Bot (2010) 0.99
Etiologic diagnosis of lower respiratory tract bacterial infections using sputum samples and quantitative loop-mediated isothermal amplification. PLoS One (2012) 0.98
Estrogenic activities of extracts of Chinese licorice (Glycyrrhiza uralensis) root in MCF-7 breast cancer cells. J Steroid Biochem Mol Biol (2009) 0.97
Mo K- and L-edge X-ray absorption spectroscopic study of the ADP.AlF4--stabilized nitrogenase complex: comparison with MoFe protein in solution and single crystal. J Synchrotron Radiat (2004) 0.97
Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation. J Biol Chem (2013) 0.97
Hybrid cytomegalovirus enhancer-h1 promoter-based plasmid and baculovirus vectors mediate effective RNA interference. Hum Gene Ther (2005) 0.96
MicroRNA profiling during rat ventricular maturation: A role for miR-29a in regulating cardiomyocyte cell cycle re-entry. FEBS Lett (2013) 0.96
Gold nanorod-based localized surface plasmon resonance biosensor for sensitive detection of hepatitis B virus in buffer, blood serum and plasma. Biosens Bioelectron (2010) 0.96
Metastatic progression of pancreatic cancer: changes in antioxidant enzymes and cell growth. Clin Exp Metastasis (2006) 0.95
An aporphine alkaloid from Nelumbo nucifera as an acetylcholinesterase inhibitor and the primary investigation for structure-activity correlations. Nat Prod Res (2011) 0.95
Genotypic variation in element concentrations in brown rice from Yunnan landraces in China. Environ Geochem Health (2009) 0.95
KIT mutations confer a distinct gene expression signature in core binding factor leukaemia. Br J Haematol (2010) 0.94
Cisplatin induces platelet apoptosis through the ERK signaling pathway. Thromb Res (2012) 0.94
Ginsenoside Rb1 inhibits osteoclastogenesis by modulating NF-κB and MAPKs pathways. Food Chem Toxicol (2012) 0.93
Inositol hexakisphosphate-dependent processing of Clostridium sordellii lethal toxin and Clostridium novyi alpha-toxin. J Biol Chem (2011) 0.93
Structure of the processive rubber oxygenase RoxA from Xanthomonas sp. Proc Natl Acad Sci U S A (2013) 0.93
Crystal structure of the NADH:quinone oxidoreductase WrbA from Escherichia coli. J Bacteriol (2007) 0.93
Mitochondrial DNA depletion induces radioresistance by suppressing G2 checkpoint activation in human pancreatic cancer cells. Radiat Res (2009) 0.93
Simultaneous determination of L-ascorbic acid, dopamine and uric acid with gold nanoparticles-β-cyclodextrin-graphene-modified electrode by square wave voltammetry. Talanta (2012) 0.92
Novel mutations of the SPG11 gene in hereditary spastic paraplegia with thin corpus callosum. J Neurol Sci (2008) 0.92
cAMP activates TRPC6 channels via the phosphatidylinositol 3-kinase (PI3K)-protein kinase B (PKB)-mitogen-activated protein kinase kinase (MEK)-ERK1/2 signaling pathway. J Biol Chem (2011) 0.92
Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. FEBS J (2010) 0.92
Epidemiological investigation in outpatients with symptomatic gastroesophageal reflux from the Department of Medicine in Zhejiang Province, east China. J Gastroenterol Hepatol (2007) 0.92