Published in Mol Neurobiol on April 19, 2011
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers. Mol Syst Biol (2012) 1.27
A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects. Front Genet (2014) 0.95
Dopamine Genetics and Function in Food and Substance Abuse. J Genet Syndr Gene Ther (2013) 0.84
Autoimmune Aspects of Neurodegenerative and Psychiatric Diseases: A Template for Innovative Therapy. Front Psychiatry (2017) 0.78
Abdominal fat is associated with a greater brain reward response to high-calorie food cues in Hispanic women. Obesity (Silver Spring) (2013) 0.78
Familial risk for alcohol dependence and developmental changes in BMI: the moderating influence of addiction and obesity genes. Pharmacogenomics (2014) 0.78
Epigenetic and Proteomic Expression Changes Promoted by Eating Addictive-Like Behavior. Neuropsychopharmacology (2015) 0.78
Low Dopamine D2 Receptor Increases Vulnerability to Obesity Via Reduced Physical Activity, Not Increased Appetitive Motivation. Biol Psychiatry (2015) 0.77
A psycho-genetic study of hedonic responsiveness in relation to "food addiction". Nutrients (2014) 0.77
Palatable Hyper-Caloric Foods Impact on Neuronal Plasticity. Front Behav Neurosci (2017) 0.75
Weight control and behavior rehabilitation in a patient suffering from Prader Willi syndrome. BMC Res Notes (2016) 0.75
Genetic Effects on Longitudinal Changes from Healthy to Adverse Weight and Metabolic Status - The HUNT Study. PLoS One (2015) 0.75
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med (2002) 101.79
Obesity and the environment: where do we go from here? Science (2003) 16.23
Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr (2004) 8.64
Brain dopamine and obesity. Lancet (2001) 8.00
Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake. Neurosci Biobehav Rev (2007) 5.22
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A (1998) 4.67
Dietary fat intake does affect obesity! Am J Clin Nutr (1998) 4.26
Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr (2004) 3.96
Obesity and the food environment: dietary energy density and diet costs. Am J Prev Med (2004) 3.90
The leptin receptor. J Biol Chem (1997) 3.76
Differential activation of the dorsal striatum by high-calorie visual food stimuli in obese individuals. Neuroimage (2007) 3.25
Drug addiction: the neurobiology of behaviour gone awry. Nat Rev Neurosci (2004) 3.13
Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers. Mol Psychiatry (1999) 2.90
Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. Hum Mutat (2004) 2.89
The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry (1998) 2.88
Distinct functions of the two isoforms of dopamine D2 receptors. Nature (2000) 2.83
Obesity, insulin resistance and diabetes--a worldwide epidemic. Br J Nutr (2000) 2.66
Reward deficiency syndrome: genetic aspects of behavioral disorders. Prog Brain Res (2000) 2.58
Leptin: the tale of an obesity gene. Diabetes (1996) 2.37
Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry (1991) 2.30
D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics (1997) 2.28
The genetic basis for smoking behavior: a systematic review and meta-analysis. Nicotine Tob Res (2004) 2.28
Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation. Proc Natl Acad Sci U S A (2009) 2.27
Reward circuitry responsivity to food predicts future increases in body mass: moderating effects of DRD2 and DRD4. Neuroimage (2010) 2.18
Exposure to appetitive food stimuli markedly activates the human brain. Neuroimage (2004) 2.13
"Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse (2002) 2.13
The D2 dopamine receptor gene as a determinant of reward deficiency syndrome. J R Soc Med (1996) 1.98
Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. Hum Mol Genet (2006) 1.94
Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments. Neuroscience (1999) 1.86
The dopamine D2 receptor (DRD2) gene: a genetic risk factor in smoking. Pharmacogenetics (1996) 1.81
Energy-dense diets are associated with lower diet costs: a community study of French adults. Public Health Nutr (2004) 1.80
Dopamine for "wanting" and opioids for "liking": a comparison of obese adults with and without binge eating. Obesity (Silver Spring) (2009) 1.65
Consumption of energy-dense, nutrient-poor foods by adult Americans: nutritional and health implications. The third National Health and Nutrition Examination Survey, 1988-1994. Am J Clin Nutr (2000) 1.63
Genetic variation in the leptin receptor gene, leptin, and weight gain in young Dutch adults. Obes Res (2003) 1.63
Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias. Mol Psychiatry (2007) 1.56
The epigenetic landscape of addiction. Ann N Y Acad Sci (2011) 1.51
Fat and sugar: an economic analysis. J Nutr (2003) 1.46
High-fructose corn syrup causes characteristics of obesity in rats: increased body weight, body fat and triglyceride levels. Pharmacol Biochem Behav (2010) 1.44
Increased prevalence of the Taq I A1 allele of the dopamine receptor gene (DRD2) in obesity with comorbid substance use disorder: a preliminary report. Pharmacogenetics (1996) 1.43
D2 dopamine receptor gene and cigarette smoking: a reward gene? Med Hypotheses (1994) 1.42
Associations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study. J Clin Endocrinol Metab (2000) 1.39
After daily bingeing on a sucrose solution, food deprivation induces anxiety and accumbens dopamine/acetylcholine imbalance. Physiol Behav (2008) 1.34
D2 dopamine receptor gene and obesity. Int J Eat Disord (1994) 1.30
Allelic association of the D2 dopamine receptor gene with cocaine dependence. Drug Alcohol Depend (1993) 1.27
Genetic variants of the human obesity (OB) gene: association with body mass index in young women, psychiatric symptoms, and interaction with the dopamine D2 receptor (DRD2) gene. Mol Psychiatry (1996) 1.23
Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors. J Biol Chem (2010) 1.23
Long-term efficacy of soy-based meal replacements vs an individualized diet plan in obese type II DM patients: relative effects on weight loss, metabolic parameters, and C-reactive protein. Eur J Clin Nutr (2005) 1.21
Exonic and intronic sequence variation in the human leptin receptor gene (LEPR). Diabetes (1997) 1.16
Sugar-dependent rats show enhanced intake of unsweetened ethanol. Alcohol (2005) 1.11
The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatment. Am J Med Genet (2000) 1.10
Dopamine D2 receptors in signal transduction and behavior. Crit Rev Neurobiol (1997) 1.03
Brain neurotransmitters in food and drug reward. Am J Clin Nutr (1985) 1.00
Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women. Int J Obes Relat Metab Disord (2001) 1.00
Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians. Hum Mol Genet (1997) 0.93
Genetic predisposition in alcoholism: association of the D2 dopamine receptor TaqI B1 RFLP with severe alcoholics. Alcohol (1993) 0.92
Assessment of coronary artery disease in patients with (a)symptomatic diabetes. Eur Heart J (2006) 0.83
Inflammatory state and stress condition in weight-lowering Lys109Arg LEPR gene polymorphism carriers. Arch Med Res (2009) 0.79
Genetic studies of the leptin receptor gene in morbidly obese French Caucasian families. Hum Genet (1997) 0.79
DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene (2002) 1.89
Randomized clinical trial of brewed green and black tea in men with prostate cancer prior to prostatectomy. Prostate (2014) 1.47
Immune response in lung cancer mouse model mimics human anti-Hu reactivity. J Neuroimmunol (2009) 1.47
Influence of exercise activity on quality of life in long-term breast cancer survivors. Qual Life Res (2005) 1.26
Extreme obesity reduces bone mineral density: complementary evidence from mice and women. Obesity (Silver Spring) (2007) 1.16
Bioavailability and antioxidant effect of epigallocatechin gallate administered in purified form versus as green tea extract in healthy individuals. J Nutr Biochem (2005) 1.02
Cranberry does not affect prothrombin time in male subjects on warfarin. J Am Diet Assoc (2006) 0.96
Impact of protein supplementation and care and support on body composition and CD4 count among HIV-infected women living in rural India: results from a randomized pilot clinical trial. AIDS Behav (2013) 0.92
A controlled trial of protein enrichment of meal replacements for weight reduction with retention of lean body mass. Nutr J (2008) 0.91
Low level anti-Hu reactivity: A risk marker for small cell lung cancer? Cancer Detect Prev (2008) 0.88
Epigenetic effects of green tea polyphenols in cancer. Epigenomics (2013) 0.87
Walnuts improve semen quality in men consuming a Western-style diet: randomized control dietary intervention trial. Biol Reprod (2012) 0.86
Protein-enriched meal replacements do not adversely affect liver, kidney or bone density: an outpatient randomized controlled trial. Nutr J (2010) 0.86
Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer. Mol Nutr Food Res (2013) 0.85
Arginine and antioxidant supplement on performance in elderly male cyclists: a randomized controlled trial. J Int Soc Sports Nutr (2010) 0.81
The roles of herbal remedies in survival and quality of life among long-term breast cancer survivors--results of a prospective study. BMC Cancer (2011) 0.76