Published in Cell Cycle on May 15, 2011
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance. Oncotarget (2012) 1.96
Local and global functions of Timeless and Tipin in replication fork protection. Cell Cycle (2012) 1.15
Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies. Biochim Biophys Acta (2013) 0.97
A prognostic signature of G(2) checkpoint function in melanoma cell lines. Cell Cycle (2013) 0.86
Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle (2012) 0.82
The human Tim-Tipin complex interacts directly with DNA polymerase epsilon and stimulates its synthetic activity. J Biol Chem (2013) 0.81
Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway. Nucleic Acids Res (2015) 0.81
Linking chromosome duplication and segregation via sister chromatid cohesion. Methods Mol Biol (2014) 0.79
Tipin functions in the protection against topoisomerase I inhibitor. J Biol Chem (2014) 0.77
Division of labor of the replication fork protection complex subunits in sister chromatid cohesion and Chk1 activation. Cell Cycle (2011) 0.76
TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin. J Biol Chem (2016) 0.75
Timeless makes some time for itself. Cell Cycle (2011) 0.75
Cell-Type Specific Responses to DNA Replication Stress in Early C. elegans Embryos. PLoS One (2016) 0.75
ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol (2008) 11.86
The cohesin ring concatenates sister DNA molecules. Nature (2008) 3.58
Sister chromatid cohesion: a simple concept with a complex reality. Annu Rev Cell Dev Biol (2008) 2.99
Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint. Mol Cell (2008) 2.63
Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol (2007) 2.54
Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication. Curr Biol (2006) 2.47
Identification of protein complexes required for efficient sister chromatid cohesion. Mol Biol Cell (2004) 2.34
Coupling of human circadian and cell cycles by the timeless protein. Mol Cell Biol (2005) 2.24
An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Mol Cell Biol (2002) 2.19
Human claspin is required for replication checkpoint control. J Biol Chem (2003) 2.02
Chromosome cohesion is regulated by a clock gene paralogue TIM-1. Nature (2003) 1.90
S-phase checkpoint genes safeguard high-fidelity sister chromatid cohesion. Mol Biol Cell (2004) 1.88
Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc Natl Acad Sci U S A (2006) 1.81
Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol (2005) 1.74
Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1. J Biol Chem (2004) 1.70
Cohesin and human disease. Annu Rev Genomics Hum Genet (2008) 1.68
Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase. Oncogene (1999) 1.68
Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors. J Mol Biol (2006) 1.66
Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint. J Biol Chem (2006) 1.62
Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem (2009) 1.54
Mrc1 is required for sister chromatid cohesion to aid in recombination repair of spontaneous damage. Mol Cell Biol (2004) 1.48
Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion. J Cell Sci (2010) 1.47
Warsaw breakage syndrome, a cohesinopathy associated with mutations in the XPD helicase family member DDX11/ChlR1. Am J Hum Genet (2010) 1.42
Claspin promotes normal replication fork rates in human cells. Mol Biol Cell (2008) 1.38
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. J Biol Chem (2010) 1.37
Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environ Health Perspect (2006) 1.34
Defective postreplication repair in xeroderma pigmentosum variant fibroblasts. Cancer Res (1990) 1.28
Genetic dissection of parallel sister-chromatid cohesion pathways. Genetics (2007) 1.26
RFCCtf18 and the Swi1-Swi3 complex function in separate and redundant pathways required for the stabilization of replication forks to facilitate sister chromatid cohesion in Schizosaccharomyces pombe. Mol Biol Cell (2007) 1.25
Sister acts: coordinating DNA replication and cohesion establishment. Genes Dev (2010) 1.24
Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1. J Biol Chem (2008) 1.24
Chk1 is required to maintain claspin stability. Oncogene (2006) 1.18
Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts. Genes Cells (2009) 1.15
Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. EMBO J (2009) 1.15
Claspin, a regulator of Chk1 in DNA replication stress pathway. DNA Repair (Amst) (2004) 1.13
Can corruption of chromosome cohesion create a conduit to cancer? Nat Rev Cancer (2011) 1.12
Influence of the human cohesion establishment factor Ctf4/AND-1 on DNA replication. J Biol Chem (2010) 1.10
The human intra-S checkpoint response to UVC-induced DNA damage. Carcinogenesis (2009) 1.05
The direct binding of Mrc1, a checkpoint mediator, to Mcm6, a replication helicase, is essential for the replication checkpoint against methyl methanesulfonate-induced stress. Mol Cell Biol (2009) 1.04
Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion. J Cell Biol (2005) 1.01
Checkpoint-dependent and -independent roles of Swi3 in replication fork recovery and sister chromatid cohesion in fission yeast. PLoS One (2010) 0.87
Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage. Cell Cycle (2007) 0.81
Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23
UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters. J Natl Cancer Inst (2007) 3.85
INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis. PLoS One (2009) 2.77
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol (2007) 2.54
ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic regions. Genome Biol (2011) 2.47
Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study. J Clin Oncol (2011) 2.47
A Bayesian semiparametric joint hierarchical model for longitudinal and survival data. Biometrics (2003) 2.33
Coupling of human circadian and cell cycles by the timeless protein. Mol Cell Biol (2005) 2.24
Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging. Aging Cell (2009) 2.21
An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Mol Cell Biol (2002) 2.19
A flexible B-spline model for multiple longitudinal biomarkers and survival. Biometrics (2005) 2.05
Multiscale Adaptive Regression Models for Neuroimaging Data. J R Stat Soc Series B Stat Methodol (2011) 2.04
Cell-type-specific responses to chemotherapeutics in breast cancer. Cancer Res (2004) 2.01
Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer. J Natl Cancer Inst (2014) 1.96
Genomewide multiple-loci mapping in experimental crosses by iterative adaptive penalized regression. Genetics (2010) 1.83
Bayesian analysis for generalized linear models with nonignorably missing covariates. Biometrics (2005) 1.65
Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma. Cancer Res (2007) 1.62
Joint models for multivariate longitudinal and multivariate survival data. Biometrics (2006) 1.62
Bayesian approaches to joint cure-rate and longitudinal models with applications to cancer vaccine trials. Biometrics (2003) 1.59
Interferon alfa-2a for melanoma metastases. Lancet (2002) 1.55
Parameter estimation in longitudinal studies with outcome-dependent follow-up. Biometrics (2002) 1.47
Wavelet thresholding with bayesian false discovery rate control. Biometrics (2005) 1.46
VARIABLE SELECTION FOR REGRESSION MODELS WITH MISSING DATA. Stat Sin (2010) 1.40
REC, Drosophila MCM8, drives formation of meiotic crossovers. PLoS Genet (2005) 1.39
Structured measurement error in nutritional epidemiology: applications in the Pregnancy, Infection, and Nutrition (PIN) Study. J Am Stat Assoc (2007) 1.38
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress. J Biol Chem (2010) 1.37
Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032. Radiother Oncol (2011) 1.35
An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis. J Virol (2003) 1.35
Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environ Health Perspect (2006) 1.34
Semiparametric models for missing covariate and response data in regression models. Biometrics (2006) 1.34
Control of skin cancer by the circadian rhythm. Proc Natl Acad Sci U S A (2011) 1.34
A statistical analysis of brain morphology using wild bootstrapping. IEEE Trans Med Imaging (2007) 1.33
The role of DNA polymerase eta in translesion synthesis past platinum-DNA adducts in human fibroblasts. Cancer Res (2004) 1.30
Checkpoint regulation of replication dynamics in UV-irradiated human cells. Cell Cycle (2006) 1.28
Cdc7-Dbf4 and the human S checkpoint response to UVC. J Biol Chem (2007) 1.27
Caffeine and human DNA metabolism: the magic and the mystery. Mutat Res (2003) 1.25
Similar nucleotide excision repair capacity in melanocytes and melanoma cells. Cancer Res (2010) 1.21
Cell cycle checkpoint function in bladder cancer. J Natl Cancer Inst (2003) 1.21
Origin licensing and p53 status regulate Cdk2 activity during G(1). Cell Cycle (2009) 1.20
ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase. J Biol Chem (2002) 1.20
Bayesian methods for missing covariates in cure rate models. Lifetime Data Anal (2002) 1.18
Bayesian Variable Selection and Computation for Generalized Linear Models with Conjugate Priors. Bayesian Anal (2008) 1.17
Bayesian design of noninferiority trials for medical devices using historical data. Biometrics (2011) 1.17
Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes. BMC Bioinformatics (2007) 1.14
Postdiagnosis change in bodyweight and survival after breast cancer diagnosis. Epidemiology (2012) 1.14
Estimating treatment effects with treatment switching via semicompeting risks models: an application to a colorectal cancer study. Biometrika (2011) 1.13
Maximum likelihood methods for nonignorable missing responses and covariates in random effects models. Biometrics (2003) 1.12
Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression. J Invest Dermatol (2007) 1.11
Theory and Inference for Regression Models with Missing Responses and Covariates. J Multivar Anal (2008) 1.11
A note on permutation tests for variance components in multilevel generalized linear mixed models. Biometrics (2007) 1.10
PERTURBATION AND SCALED COOK'S DISTANCE. Ann Stat (2012) 1.09
A weighted estimating equation for linear regression with missing covariate data. Stat Med (2002) 1.08
In vitro hepatic metabolism explains higher clearance of voriconazole in children versus adults: role of CYP2C19 and flavin-containing monooxygenase 3. Drug Metab Dispos (2010) 1.08
Maximum Likelihood Inference for the Cox Regression Model with Applications to Missing Covariates. J Multivar Anal (2009) 1.08
Intrinsic Regression Models for Positive-Definite Matrices With Applications to Diffusion Tensor Imaging. J Am Stat Assoc (2009) 1.07
Estimation in regression models for longitudinal binary data with outcome-dependent follow-up. Biostatistics (2006) 1.06
Regression Models for Identifying Noise Sources in Magnetic Resonance Images. J Am Stat Assoc (2009) 1.06
Deletion of hepatocyte nuclear factor-1-beta in an infant with prune belly syndrome. Am J Perinatol (2010) 1.05
Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. Toxicol Sci (2007) 1.04
A class of Bayesian shared gamma frailty models with multivariate failure time data. Biometrics (2005) 1.04
Sample size and power determination in joint modeling of longitudinal and survival data. Stat Med (2011) 1.04
Assessing model fit in joint models of longitudinal and survival data with applications to cancer clinical trials. Stat Med (2014) 1.01
Same origins of DNA replication function on the active and inactive human X chromosomes. J Cell Biochem (2003) 1.01
Pseudo-likelihood methods for longitudinal binary data with non-ignorable missing responses and covariates. Stat Med (2006) 1.00
Mapping of an origin of DNA replication near the transcriptional promoter of the human HPRT gene. J Cell Biochem (2002) 0.99
Intrinsic Regression Models for Manifold-Valued Data. J Am Stat Assoc (2009) 0.98
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain-mediated PUMA degradation. J Invest Dermatol (2013) 0.97
A prognostic signature of defective p53-dependent G1 checkpoint function in melanoma cell lines. Pigment Cell Melanoma Res (2012) 0.97
Could BRAF mutations in melanocytic lesions arise from DNA damage induced by ultraviolet radiation? J Invest Dermatol (2006) 0.96
Bayesian case influence diagnostics for survival models. Biometrics (2008) 0.96
Local influence for generalized linear models with missing covariates. Biometrics (2009) 0.96
Ubiquitylation of proliferating cell nuclear antigen and recruitment of human DNA polymerase eta. Biochemistry (2008) 0.96
Current Methods for Recurrent Events Data with Dependent Termination: A Bayesian Perspective. J Am Stat Assoc (2008) 0.96
Use of historical control data for assessing treatment effects in clinical trials. Pharm Stat (2013) 0.95
A mathematical model for human nucleotide excision repair: damage recognition by random order assembly and kinetic proofreading. J Theor Biol (2007) 0.95
Human papilloma virus type16 E6 deregulates CHK1 and sensitizes human fibroblasts to environmental carcinogens independently of its effect on p53. Cell Cycle (2009) 0.95
Maximum likelihood estimation in generalized linear models with multiple covariates subject to detection limits. Stat Med (2011) 0.95
ATM requirement in gene expression responses to ionizing radiation in human lymphoblasts and fibroblasts. Mol Cancer Res (2006) 0.94
Variable selection in the cox regression model with covariates missing at random. Biometrics (2009) 0.94
Clonal evolution of lymphoblastoid cell lines. Lab Invest (2006) 0.93
Proximity model for expression quantitative trait loci (eQTL) detection. Biometrics (2007) 0.93
DNA damage responses protect xeroderma pigmentosum variant from UVC-induced clastogenesis. Carcinogenesis (2002) 0.92
Frailty models with missing covariates. Biometrics (2002) 0.92