Published in J Biol Chem on March 15, 2010
The DNA damage response: making it safe to play with knives. Mol Cell (2010) 16.13
More forks on the road to replication stress recovery. J Mol Cell Biol (2011) 1.64
Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts. Cell Cycle (2011) 1.54
Modulation of DNA damage and repair pathways by human tumour viruses. Viruses (2015) 1.49
Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J (2012) 1.47
DNA damage tolerance: a double-edged sword guarding the genome. Transl Cancer Res (2013) 1.33
Local and global functions of Timeless and Tipin in replication fork protection. Cell Cycle (2012) 1.15
RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response. Cell Res (2014) 1.10
Altered replication in human cells promotes DMPK (CTG)(n) · (CAG)(n) repeat instability. Mol Cell Biol (2012) 0.92
Human single-stranded DNA binding proteins are essential for maintaining genomic stability. BMC Mol Biol (2013) 0.91
Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases. Proc Natl Acad Sci U S A (2013) 0.90
Characterization of functional domains in human Claspin. Cell Cycle (2011) 0.87
The fork and the kinase: a DNA replication tale from a CHK1 perspective. Mutat Res Rev Mutat Res (2014) 0.87
Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1. Nucleic Acids Res (2014) 0.85
The replisome pausing factor Timeless is required for episomal maintenance of latent Epstein-Barr virus. J Virol (2011) 0.84
Timeless links replication termination to mitotic kinase activation. PLoS One (2011) 0.84
Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy. Oncotarget (2014) 0.84
The intra-S phase checkpoint protein Tof1 collaborates with the helicase Rrm3 and the F-box protein Dia2 to maintain genome stability in Saccharomyces cerevisiae. J Biol Chem (2010) 0.83
DNA mismatch repair and the DNA damage response. DNA Repair (Amst) (2015) 0.83
Circadian clock circuitry in colorectal cancer. World J Gastroenterol (2014) 0.82
Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle (2012) 0.82
Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates. PLoS One (2011) 0.82
Circadian transcriptome analysis in human fibroblasts from Hunter syndrome and impact of iduronate-2-sulfatase treatment. BMC Med Genomics (2013) 0.81
Molecular mechanisms of DNA replication checkpoint activation. Genes (Basel) (2014) 0.80
CRY2 and FBXL3 Cooperatively Degrade c-MYC. Mol Cell (2016) 0.79
Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress. Cell Rep (2016) 0.79
RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling. Cell Cycle (2015) 0.79
And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress. EMBO J (2015) 0.78
Investigation of N-Terminal Phospho-Regulation of Uracil DNA Glycosylase Using Protein Semisynthesis. Biophys J (2017) 0.78
Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest. Proc Natl Acad Sci U S A (2016) 0.77
BRCA1-dependent Chk1 phosphorylation triggers partial chromatin disassociation of phosphorylated Chk1 and facilitates S-phase cell cycle arrest. Int J Biochem Cell Biol (2012) 0.77
Prospects for the Use of ATR Inhibitors to Treat Cancer. Pharmaceuticals (Basel) (2010) 0.77
Tipin functions in the protection against topoisomerase I inhibitor. J Biol Chem (2014) 0.77
The biological clock and the molecular basis of lysosomal storage diseases. JIMD Rep (2015) 0.76
Division of labor of the replication fork protection complex subunits in sister chromatid cohesion and Chk1 activation. Cell Cycle (2011) 0.76
DNA damage checkpoint responses in the S phase of synchronized diploid human fibroblasts. Photochem Photobiol (2014) 0.76
TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin. J Biol Chem (2016) 0.75
Insulin-like growth factor-1 receptor signaling is required for optimal ATR-CHK1 kinase signaling in UVB-irradiated human keratinocytes. J Biol Chem (2016) 0.75
Retracted Expression of PER, CRY, and TIM genes for the pathological features of colorectal cancer patients. Onco Targets Ther (2016) 0.75
Research highlights on a notable retrovirus and a popular guardian gene. Cell Cycle (2010) 0.75
Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint. Photochem Photobiol (2016) 0.75
Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption. Aging (Albany NY) (2017) 0.75
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism. Nat Genet (2017) 0.75
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science (2007) 20.11
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science (2003) 18.29
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem (2004) 14.93
ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol (2008) 11.86
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev (2000) 11.49
How shelterin protects mammalian telomeres. Annu Rev Genet (2008) 11.20
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. Annu Rev Biochem (1997) 9.83
Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis. Mol Cell Biol (2000) 9.21
ATR and ATRIP: partners in checkpoint signaling. Science (2001) 7.58
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol (2001) 7.26
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol (2006) 6.52
Recombinant replication protein A: expression, complex formation, and functional characterization. J Biol Chem (1994) 6.41
TopBP1 activates the ATR-ATRIP complex. Cell (2006) 6.29
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res (2006) 4.49
Cellular factors required for multiple stages of SV40 DNA replication in vitro. EMBO J (1988) 4.37
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene (2007) 3.68
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol Cell (2000) 3.65
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev (2007) 3.58
Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. Proc Natl Acad Sci U S A (2004) 3.12
Profiling of UV-induced ATM/ATR signaling pathways. Proc Natl Acad Sci U S A (2007) 3.12
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Mol Biol Cell (2005) 3.08
Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol Cell (2005) 2.75
ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts. Mol Cell (2006) 2.73
Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA. Cell (2000) 2.73
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol (2007) 2.54
G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer. Br J Cancer (2008) 2.33
Coupling of human circadian and cell cycles by the timeless protein. Mol Cell Biol (2005) 2.24
Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response. Curr Biol (2005) 2.13
Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation. Mol Cell Biol (2006) 2.09
Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17. Mol Cell (2003) 2.08
Function of a conserved checkpoint recruitment domain in ATRIP proteins. Mol Cell Biol (2007) 2.02
Human claspin is required for replication checkpoint control. J Biol Chem (2003) 2.02
The role of single-stranded DNA and polymerase alpha in establishing the ATR, Hus1 DNA replication checkpoint. J Biol Chem (2002) 1.92
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc Natl Acad Sci U S A (2003) 1.90
Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response. DNA Repair (Amst) (2009) 1.89
Preferential binding of ATR protein to UV-damaged DNA. Proc Natl Acad Sci U S A (2002) 1.87
Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function. Proc Natl Acad Sci U S A (2006) 1.81
RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint. J Biol Chem (2006) 1.79
Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses. J Biol Chem (2004) 1.76
Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling. EMBO J (2004) 1.75
Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors. J Mol Biol (2006) 1.66
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Mol Cell (2009) 1.64
Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation. Proc Natl Acad Sci U S A (2004) 1.62
Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint. J Biol Chem (2006) 1.62
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Proc Natl Acad Sci U S A (2007) 1.54
Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts. Proc Natl Acad Sci U S A (2007) 1.52
Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences. Mol Cell Biol (2006) 1.51
Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities. Mol Cell Biol (2004) 1.45
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress. J Cell Sci (2009) 1.44
Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association. J Mol Biol (2003) 1.40
Phosphorylation of Xenopus Rad1 and Hus1 defines a readout for ATR activation that is independent of Claspin and the Rad9 carboxy terminus. Mol Biol Cell (2006) 1.27
Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway. J Biol Chem (2009) 1.21
Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (ataxia telangiectasia-mutated and rad3-related) checkpoint kinase. J Biol Chem (2009) 1.18
Chk1 is required to maintain claspin stability. Oncogene (2006) 1.18
Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis. J Cell Biol (2009) 1.15
Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts. Genes Cells (2009) 1.15
Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. J Biol Chem (2004) 1.13
Human DNA damage response and repair deficiency syndromes: linking genomic instability and cell cycle checkpoint proficiency. DNA Repair (Amst) (2009) 1.13
Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA. Nucleic Acids Res (2009) 1.11
Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structures. Genes Dev (2006) 1.07
Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex. Mol Cell Biol (1995) 1.01
A naturally occurring human RPA subunit homolog does not support DNA replication or cell-cycle progression. Nucleic Acids Res (2009) 0.94
An alternative form of replication protein a expressed in normal human tissues supports DNA repair. J Biol Chem (2009) 0.93
An alternative form of replication protein a prevents viral replication in vitro. J Biol Chem (2008) 0.90
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem (2004) 14.93
Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol Cell Biol (2002) 5.39
Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev (2002) 4.30
Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase. J Biol Chem (2005) 3.56
Ammonia derived from glutaminolysis is a diffusible regulator of autophagy. Sci Signal (2010) 3.38
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference. Mol Biol Cell (2005) 3.04
Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin. Cancer Res (2009) 3.03
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc Natl Acad Sci U S A (2003) 2.80
Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol Cell (2005) 2.75
Targeting the mTOR signaling network in cancer. Trends Mol Med (2007) 2.66
The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol (2007) 2.54
Nucleotide excision repair. Prog Nucleic Acid Res Mol Biol (2005) 2.31
Coupling of human circadian and cell cycles by the timeless protein. Mol Cell Biol (2005) 2.24
An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Mol Cell Biol (2002) 2.19
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol Cell (2004) 2.09
Hypoxia links ATR and p53 through replication arrest. Mol Cell Biol (2002) 2.03
Direct observation of thymine dimer repair in DNA by photolyase. Proc Natl Acad Sci U S A (2005) 2.01
Cell-type-specific responses to chemotherapeutics in breast cancer. Cancer Res (2004) 2.01
Mammalian target of rapamycin: discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth. Semin Oncol (2009) 1.98
Targeting mTOR globally in cancer: thinking beyond rapamycin. Cell Cycle (2009) 1.89
Preferential binding of ATR protein to UV-damaged DNA. Proc Natl Acad Sci U S A (2002) 1.87
Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2. Cancer Res (2010) 1.86
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase. Proc Natl Acad Sci U S A (2010) 1.82
A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis. Cancer Res (2008) 1.81
A role for cryptochromes in sleep regulation. BMC Neurosci (2002) 1.81
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold. Bioorg Med Chem (2004) 1.77
DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. J Biol Chem (2001) 1.75
A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity. Proc Natl Acad Sci U S A (2006) 1.75
Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling. EMBO J (2004) 1.75
Cancer and inflammation: promise for biologic therapy. J Immunother (2010) 1.72
Circadian oscillation of nucleotide excision repair in mammalian brain. Proc Natl Acad Sci U S A (2009) 1.72
Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. Mol Cell (2002) 1.70
Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells. Cancer Res (2003) 1.69
The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin. Mol Cell Biol (2002) 1.68
Animal type 1 cryptochromes. Analysis of the redox state of the flavin cofactor by site-directed mutagenesis. J Biol Chem (2007) 1.68
Glutamine: pleiotropic roles in tumor growth and stress resistance. J Mol Med (Berl) (2011) 1.67
Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease. Genes Dev (2003) 1.65
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Mol Cell (2009) 1.64
Photochemistry and photobiology of cryptochrome blue-light photopigments: the search for a photocycle. Photochem Photobiol (2005) 1.64
Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma. Cancer Res (2007) 1.62
cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proc Natl Acad Sci U S A (2008) 1.62
The phosphatidylinositol 3-kinase inhibitor, PX-866, is a potent inhibitor of cancer cell motility and growth in three-dimensional cultures. Mol Cancer Ther (2007) 1.62
Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy. J Biol Chem (2002) 1.59
Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor. Biochemistry (2005) 1.58
SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site. J Immunol (2003) 1.58
Ultrafast dynamics and anionic active states of the flavin cofactor in cryptochrome and photolyase. J Am Chem Soc (2008) 1.55
Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts. Cell Cycle (2011) 1.54
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Proc Natl Acad Sci U S A (2007) 1.54
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proc Natl Acad Sci U S A (2010) 1.53
Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer. Cancer Res (2005) 1.53
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1. Nat Cell Biol (2003) 1.53
Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences. Mol Cell Biol (2006) 1.51
The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle. Mol Cell Biol (2002) 1.49
The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1. Proc Natl Acad Sci U S A (2004) 1.49
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation. Genes Dev (2004) 1.47
The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenografts. Mol Cancer Ther (2005) 1.46
Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase. Proc Natl Acad Sci U S A (2011) 1.45
Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities. Mol Cell Biol (2004) 1.45
Purification and characterization of Escherichia coli and human nucleotide excision repair enzyme systems. Methods Enzymol (2006) 1.45
The intelligent clock and the Rube Goldberg clock. Nat Struct Mol Biol (2008) 1.43
Reaction mechanism of Drosophila cryptochrome. Proc Natl Acad Sci U S A (2010) 1.42
Formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly. J Biol Chem (2007) 1.42
Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyase. Nature (2010) 1.40
Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer. Cancer Res (2005) 1.38
ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background. EMBO J (2004) 1.36
Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032. Radiother Oncol (2011) 1.35
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C. J Cell Biol (2002) 1.35
Loss of cryptochrome reduces cancer risk in p53 mutant mice. Proc Natl Acad Sci U S A (2009) 1.35
Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environ Health Perspect (2006) 1.34
Control of skin cancer by the circadian rhythm. Proc Natl Acad Sci U S A (2011) 1.34
Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1. Nat Immunol (2005) 1.32
Repair of DNA-polypeptide crosslinks by human excision nuclease. Proc Natl Acad Sci U S A (2006) 1.31
Identification and characterization of human MUS81-MMS4 structure-specific endonuclease. J Biol Chem (2003) 1.30
The role of DNA polymerase eta in translesion synthesis past platinum-DNA adducts in human fibroblasts. Cancer Res (2004) 1.30
Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line. EMBO J (2002) 1.28
Checkpoint regulation of replication dynamics in UV-irradiated human cells. Cell Cycle (2006) 1.28
Biochemical analysis of the canonical model for the mammalian circadian clock. J Biol Chem (2011) 1.27
Cdc7-Dbf4 and the human S checkpoint response to UVC. J Biol Chem (2007) 1.27
Nucleotide excision repair from site-specifically platinum-modified nucleosomes. Biochemistry (2003) 1.27
RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage? Proc Natl Acad Sci U S A (2007) 1.26
Molecular anatomy of the human excision nuclease assembled at sites of DNA damage. Mol Cell Biol (2002) 1.26
Analysis of the role of intraprotein electron transfer in photoreactivation by DNA photolyase in vivo. Biochemistry (2004) 1.26
Caffeine and human DNA metabolism: the magic and the mystery. Mutat Res (2003) 1.25
The PI3K, metabolic, and autophagy networks: interactive partners in cellular health and disease. Annu Rev Pharmacol Toxicol (2013) 1.25
Ultrafast dynamics of flavins in five redox states. J Am Chem Soc (2008) 1.25
Light induction of a vertebrate clock gene involves signaling through blue-light receptors and MAP kinases. Curr Biol (2002) 1.23
4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4 (CDK4). J Med Chem (2008) 1.23
Circadian regulation of DNA excision repair: implications for chrono-chemotherapy. Cell Cycle (2009) 1.22