Published in Am J Hum Genet on February 04, 2010
DNA helicases involved in DNA repair and their roles in cancer. Nat Rev Cancer (2013) 1.58
Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts. Cell Cycle (2011) 1.54
Incidental medical information in whole-exome sequencing. Pediatrics (2012) 1.48
RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res (2010) 1.27
Sister acts: coordinating DNA replication and cohesion establishment. Genes Dev (2010) 1.24
DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster. Nucleic Acids Res (2012) 1.20
Biochemical characterization of Warsaw breakage syndrome helicase. J Biol Chem (2011) 1.19
Local and global functions of Timeless and Tipin in replication fork protection. Cell Cycle (2012) 1.15
Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal-Hreidarsson syndrome. Proc Natl Acad Sci U S A (2013) 1.13
G4-associated human diseases. EMBO Rep (2015) 1.10
SMC complexes: from DNA to chromosomes. Nat Rev Mol Cell Biol (2016) 1.07
Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies. Front Genet (2012) 1.06
Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes. J Clin Invest (2015) 1.05
Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder. Br J Haematol (2015) 1.01
DNA and RNA quadruplex-binding proteins. Int J Mol Sci (2014) 1.01
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem (2013) 0.99
Emerging critical roles of Fe-S clusters in DNA replication and repair. Biochim Biophys Acta (2015) 0.96
Disease-causing missense mutations in human DNA helicase disorders. Mutat Res (2012) 0.95
Diagnostic Overlap between Fanconi Anemia and the Cohesinopathies: Roberts Syndrome and Warsaw Breakage Syndrome. Anemia (2010) 0.95
Compromised structure and function of HDAC8 mutants identified in Cornelia de Lange Syndrome spectrum disorders. ACS Chem Biol (2014) 0.95
Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome. Cell Mol Life Sci (2014) 0.95
Inference of tumor phylogenies from genomic assays on heterogeneous samples. J Biomed Biotechnol (2012) 0.94
Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response. Mol Cell Biol (2013) 0.93
Mutations in SGOL1 cause a novel cohesinopathy affecting heart and gut rhythm. Nat Genet (2014) 0.93
Identification and biochemical characterization of a novel mutation in DDX11 causing Warsaw breakage syndrome. Hum Mutat (2012) 0.90
Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae. PLoS One (2013) 0.89
Cohesinopathies of a feather flock together. PLoS Genet (2013) 0.87
Mammalian ChlR1 has a role in heterochromatin organization. Exp Cell Res (2011) 0.84
The DEAD/DEAH box helicase, DDX11, is essential for the survival of advanced melanomas. Mol Cancer (2012) 0.83
Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers. DNA Repair (Amst) (2014) 0.83
DNA helicases associated with genetic instability, cancer, and aging. Adv Exp Med Biol (2013) 0.83
The roles of cohesins in mitosis, meiosis, and human health and disease. Methods Mol Biol (2014) 0.82
Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome. Mol Cell (2016) 0.81
Roles of ChlR1 DNA helicase in replication recovery from DNA damage. Exp Cell Res (2013) 0.81
Tim/Timeless, a member of the replication fork protection complex, operates with the Warsaw breakage syndrome DNA helicase DDX11 in the same fork recovery pathway. Nucleic Acids Res (2015) 0.81
The Arabidopsis thaliana homolog of the helicase RTEL1 plays multiple roles in preserving genome stability. Plant Cell (2014) 0.80
A distinct triplex DNA unwinding activity of ChlR1 helicase. J Biol Chem (2015) 0.80
Put on your thinking cap: G-quadruplexes, helicases, and telomeres. Aging (Albany NY) (2011) 0.80
Linking chromosome duplication and segregation via sister chromatid cohesion. Methods Mol Biol (2014) 0.79
DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion. J Biol Chem (2012) 0.79
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. Nat Commun (2015) 0.77
A patient with polymerase E1 deficiency (POLE1): clinical features and overlap with DNA breakage/instability syndromes. BMC Med Genet (2015) 0.77
The Q Motif Is Involved in DNA Binding but Not ATP Binding in ChlR1 Helicase. PLoS One (2015) 0.76
Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome. Dis Model Mech (2015) 0.76
Setting the stage for cohesion establishment by the replication fork. Cell Cycle (2012) 0.75
Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion. Oncotarget (2016) 0.75
Helicases and human diseases. Front Genet (2015) 0.75
The cellular DNA helicase ChlR1 regulates chromatin and nuclear matrix attachment of the human papillomavirus type 16 E2 protein and high copy viral genome establishment. J Virol (2016) 0.75
Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion. Nat Genet (2005) 2.77
Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion. Genetics (2004) 1.76
Structure, function and evolution of the XPD family of iron-sulfur-containing 5'-->3' DNA helicases. Biochem Soc Trans (2009) 1.69
Welcome the family of FANCJ-like helicases to the block of genome stability maintenance proteins. Cell Mol Life Sci (2009) 1.54
The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells. J Cell Sci (2006) 1.42
ChlR1 is required for loading papillomavirus E2 onto mitotic chromosomes and viral genome maintenance. Mol Cell (2006) 1.39
Characterization of the enzymatic activity of hChlR1, a novel human DNA helicase. Nucleic Acids Res (2000) 1.38
Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation. Cell Cycle (2007) 1.25
Biallelic inactivation of BRCA2 in Fanconi anemia. Science (2002) 9.31
Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. Cancer Res (2006) 6.28
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet (2006) 4.98
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J. Nat Genet (2005) 4.92
A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet (2003) 4.79
A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M. Nat Genet (2005) 4.57
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. Mol Cell (2007) 4.28
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med (2003) 4.04
Mutations in the pericentrin (PCNT) gene cause primordial dwarfism. Science (2008) 4.04
A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome. Mol Cell Biol (2003) 3.85
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet (2011) 3.74
X-linked inheritance of Fanconi anemia complementation group B. Nat Genet (2004) 2.86
Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion. Nat Genet (2005) 2.77
Identification of the Fanconi anemia complementation group I gene, FANCI. Cell Oncol (2007) 2.50
The genetic and molecular basis of Fanconi anemia. Mutat Res (2008) 2.45
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M. Blood (2009) 2.33
Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia. Am J Hum Genet (2013) 2.15
Fanconi anemia and DNA replication repair. DNA Repair (Amst) (2007) 2.09
FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway. EMBO J (2007) 2.00
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. Hum Mol Genet (2004) 1.95
Fanconi anemia: adult head and neck cancer and hematopoietic mosaicism. Arch Otolaryngol Head Neck Surg (2005) 1.91
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev (2010) 1.88
Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell (2009) 1.85
Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks. Mol Cell Biol (2006) 1.82
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Hum Mol Genet (2004) 1.73
Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes. Blood (2003) 1.71
Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype. Am J Hum Genet (2007) 1.67
Small supernumerary marker chromosomes (SMCs): genotype-phenotype correlation and classification. Hum Genet (2003) 1.57
Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair. Hum Mol Genet (2007) 1.56
Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder. Am J Hum Genet (2009) 1.54
The Fanconi anemia pathway of genomic maintenance. Cell Oncol (2006) 1.52
FANCE: the link between Fanconi anaemia complex assembly and activity. EMBO J (2002) 1.47
Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. Hum Mol Genet (2009) 1.47
Evidence for subcomplexes in the Fanconi anemia pathway. Blood (2006) 1.43
Alternative end joining during switch recombination in patients with ataxia-telangiectasia. Eur J Immunol (2002) 1.42
Should chromosome breakage studies be performed in patients with VACTERL association? Am J Med Genet A (2005) 1.42
Clinical and molecular characteristics of squamous cell carcinomas from Fanconi anemia patients. J Natl Cancer Inst (2008) 1.36
Genetic subtyping of Fanconi anemia by comprehensive mutation screening. Hum Mutat (2008) 1.34
The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks. Mol Cell (2013) 1.32
Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice. Hum Mol Genet (2002) 1.29
Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs. DNA Repair (Amst) (2008) 1.29
The mammalian XRCC genes: their roles in DNA repair and genetic stability. DNA Repair (Amst) (2003) 1.26
Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2. Cancer Res (2003) 1.23
Homologous sequences at human chromosome 9 bands p12 and q13-21.1 are involved in different patterns of pericentric rearrangements. Eur J Hum Genet (2002) 1.19
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Mol Cell (2012) 1.19
Biochemical characterization of Warsaw breakage syndrome helicase. J Biol Chem (2011) 1.19
Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function. Mutat Res (2006) 1.17
Delineation of the role of the Mre11 complex in class switch recombination. J Biol Chem (2004) 1.16
Impaired DNA damage-induced nuclear Rad51 foci formation uniquely characterizes Fanconi anemia group D1. Oncogene (2002) 1.15
Inducibility of nuclear Rad51 foci after DNA damage distinguishes all Fanconi anemia complementation groups from D1/BRCA2. Mutat Res (2005) 1.15
Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52. Mutat Res (2005) 1.14
Spontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients. J Clin Invest (2010) 1.13
Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients. Cancer Res (2005) 1.12
The XRCC genes: expanding roles in DNA double-strand break repair. DNA Repair (Amst) (2004) 1.11