Published in Cell Metab on May 04, 2011
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation. Nat Immunol (2014) 3.31
SREBPs: metabolic integrators in physiology and metabolism. Trends Endocrinol Metab (2011) 2.29
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells. Immunity (2012) 2.14
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity (2012) 1.96
Expanding roles for SREBP in metabolism. Cell Metab (2012) 1.76
Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production. J Biol Chem (2012) 1.75
Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development. Dis Model Mech (2013) 1.55
Sterols and oxysterols in immune cell function. Nat Immunol (2013) 1.41
Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis. Nat Immunol (2013) 1.36
Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility. Circulation (2013) 1.25
Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. J Cereb Blood Flow Metab (2014) 1.20
Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia). PLoS One (2012) 1.17
Implication of inflammatory signaling pathways in obesity-induced insulin resistance. Front Endocrinol (Lausanne) (2013) 1.09
CCAAT/enhancer-binding protein β (C/EBPβ) expression regulates dietary-induced inflammation in macrophages and adipose tissue in mice. J Biol Chem (2012) 1.07
NLRP1a expression in Srebp-1a-deficient mice. Cell Metab (2014) 1.07
Macrophage migration inhibitory factor contributes to ethanol-induced liver injury by mediating cell injury, steatohepatitis, and steatosis. Hepatology (2013) 1.03
Lipid homeostasis and the formation of macrophage-derived foam cells in atherosclerosis. Protein Cell (2012) 1.03
Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP. Semin Liver Dis (2013) 1.02
Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a. Circulation (2014) 1.00
Mechanisms of triglyceride accumulation in activated macrophages. J Leukoc Biol (2012) 0.98
Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs. PLoS One (2013) 0.97
Metabolic control of dendritic cell activation and function: recent advances and clinical implications. Front Immunol (2014) 0.92
Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes. Circ Res (2016) 0.92
Interleukin-1 beta: a potential link between stress and the development of visceral obesity. BMC Physiol (2012) 0.91
Immunometabolism: Cellular Metabolism Turns Immune Regulator. J Biol Chem (2015) 0.91
Lipoprotein subclass metabolism in nonalcoholic steatohepatitis. J Lipid Res (2014) 0.88
Control of macrophage metabolism and activation by mTOR and Akt signaling. Semin Immunol (2015) 0.87
Protection from bacterial-toxin-induced apoptosis in macrophages requires the lipogenic transcription factor sterol regulatory element binding protein 1a. Mol Cell Biol (2012) 0.86
Transcriptome analysis of genes regulated by cholesterol loading in two strains of mouse macrophages associates lysosome pathway and ER stress response with atherosclerosis susceptibility. PLoS One (2013) 0.85
s-Adenosylmethionine Levels Govern Innate Immunity through Distinct Methylation-Dependent Pathways. Cell Metab (2015) 0.84
Time and Demand are Two Critical Dimensions of Immunometabolism: The Process of Macrophage Activation and the Pentose Phosphate Pathway. Front Immunol (2015) 0.83
Transcriptional analysis of the three Nlrp1 paralogs in mice. BMC Genomics (2013) 0.82
Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins. Inflamm Res (2014) 0.82
Regulation of lipogenic gene expression by lysine-specific histone demethylase-1 (LSD1). J Biol Chem (2014) 0.82
Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis. Circulation (2013) 0.82
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol. Front Genet (2014) 0.81
Regulation of glucose metabolism from a liver-centric perspective. Exp Mol Med (2016) 0.80
SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology. Nat Rev Endocrinol (2017) 0.80
Srebp-controlled glucose metabolism is essential for NK cell functional responses. Nat Immunol (2017) 0.79
SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. Cell Metab (2016) 0.79
Early Life Exposure to Fructose Alters Maternal, Fetal and Neonatal Hepatic Gene Expression and Leads to Sex-Dependent Changes in Lipid Metabolism in Rat Offspring. PLoS One (2015) 0.79
Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet. Dis Model Mech (2016) 0.78
Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like receptor family pyrin domain-containing protein 3 inflammasome in atherosclerosis. Curr Opin Lipidol (2014) 0.78
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection. Part Fibre Toxicol (2017) 0.77
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway. PLoS Biol (2016) 0.77
The mutual interplay of lipid metabolism and the cells of the immune system in relation to atherosclerosis. Clin Lipidol (2015) 0.76
mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). PLoS One (2015) 0.76
Innate immunity: Linking lipids and inflammasomes. Nat Rev Immunol (2011) 0.75
Response to Gerlic et al. Cell Metab (2014) 0.75
Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2. Genome Biol (2015) 0.75
TIFA as a crucial mediator for NLRP3 inflammasome. Proc Natl Acad Sci U S A (2016) 0.75
Potential Metabolic Biomarkers to Identify Interstitial Lung Abnormalities. Int J Mol Sci (2016) 0.75
Sufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages. J Lipid Res (2013) 0.75
miR-31 Links Lipid Metabolism and Cell Apoptosis in Bacteria-Challenged Apostichopus japonicus via Targeting CTRP9. Front Immunol (2017) 0.75
Relationship among LRP1 expression, Pyk2 phosphorylation and MMP-9 activation in left ventricular remodelling after myocardial infarction. J Cell Mol Med (2017) 0.75
Similarities and Distinctions of Cancer and Immune Metabolism in Inflammation and Tumors. Cell Metab (2017) 0.75
Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages. Cell Rep (2017) 0.75
Atherosclerosis--an inflammatory disease. N Engl J Med (1999) 59.28
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest (2002) 21.08
The inflammasomes. Cell (2010) 19.37
Atherosclerosis. Nature (2000) 15.95
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature (2004) 14.80
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity (2006) 10.58
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell (1995) 9.11
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev (2000) 9.09
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol (2009) 7.80
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet (2006) 6.89
Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc (2009) 6.71
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature (2006) 6.28
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med (2003) 6.21
Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. J Clin Invest (1997) 6.18
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med (2007) 5.48
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science (1997) 5.16
Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. Proc Natl Acad Sci U S A (1998) 4.89
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J Clin Invest (1998) 4.85
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell (2006) 4.63
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc Natl Acad Sci U S A (2000) 4.58
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med (2010) 4.52
Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver. Proc Natl Acad Sci U S A (1995) 4.40
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell (2007) 4.33
Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe (2009) 4.20
Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med (2006) 3.76
A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. EMBO J (1993) 3.74
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci U S A (2001) 3.29
SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast. Cell (2005) 2.81
PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc Natl Acad Sci U S A (2003) 2.40
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Genes Dev (2009) 2.37
Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes. J Clin Immunol (2010) 2.16
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol Cell Biol (2003) 2.10
Effect of endotoxin in IL-1 beta-deficient mice. J Immunol (1996) 1.92
NALP inflammasomes: a central role in innate immunity. Semin Immunopathol (2007) 1.91
Critical roles of Toll-like receptors in host defense. Crit Rev Immunol (2000) 1.63
SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. J Clin Invest (2008) 1.58
Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2). J Biol Chem (2003) 1.51
Evaluation of endotoxin models for the study of sepsis. Shock (2005) 1.47
NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells. Infect Immun (2010) 1.46
Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18. J Biol Chem (2004) 1.37
A systemic granulomatous response to Schistosoma mansoni eggs alters responsiveness of bone-marrow-derived macrophages to Toll-like receptor agonists. J Leukoc Biol (2007) 1.33
Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins. Proc Natl Acad Sci U S A (2005) 1.24
IL-12, but not IL-18, is critical to neutrophil activation and resistance to polymicrobial sepsis induced by cecal ligation and puncture. J Immunol (2006) 1.08
New insight in LPS antagonist. Mini Rev Med Chem (2009) 0.98
Trichothecene mycotoxins activate inflammatory response in human macrophages. J Immunol (2009) 0.98
Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2. Mol Cell Biol (2009) 0.97
Lipid synthesis in macrophages during inflammation in vivo: effect of agonists of peroxisome proliferator activated receptors alpha and gamma and of retinoid X receptors. Biochemistry (Mosc) (2008) 0.93
A simple promoter containing two Sp1 sites controls the expression of sterol-regulatory-element-binding protein 1a (SREBP-1a). Biochem J (2005) 0.87
The RAST Server: rapid annotations using subsystems technology. BMC Genomics (2008) 175.18
The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST). Nucleic Acids Res (2013) 29.49
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The National Microbial Pathogen Database Resource (NMPDR): a genomics platform based on subsystem annotation. Nucleic Acids Res (2006) 11.15
Functional metagenomic profiling of nine biomes. Nature (2008) 11.00
The marine viromes of four oceanic regions. PLoS Biol (2006) 10.19
The knockout mouse project. Nat Genet (2004) 7.80
An application of statistics to comparative metagenomics. BMC Bioinformatics (2006) 6.29
Phylogenetic classification of short environmental DNA fragments. Nucleic Acids Res (2008) 5.12
Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab (2007) 5.04
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res (2003) 4.83
Microbial ecology of four coral atolls in the Northern Line Islands. PLoS One (2008) 4.48
Metagenomic and small-subunit rRNA analyses reveal the genetic diversity of bacteria, archaea, fungi, and viruses in soil. Appl Environ Microbiol (2007) 4.32
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell (2012) 4.09
Accessing the SEED genome databases via Web services API: tools for programmers. BMC Bioinformatics (2010) 3.99
A public gene trap resource for mouse functional genomics. Nat Genet (2004) 3.96
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem (2002) 3.58
The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res (2006) 3.40
Bacterial carbon processing by generalist species in the coastal ocean. Nature (2008) 3.37
Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation. Proc Natl Acad Sci U S A (2005) 3.30
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. Curr Biol (2007) 3.27
Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect. Proc Natl Acad Sci U S A (2002) 3.26
Lamins A and C but not lamin B1 regulate nuclear mechanics. J Biol Chem (2006) 3.02
Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase. Arterioscler Thromb Vasc Biol (2009) 2.99
Laminopathies and the long strange trip from basic cell biology to therapy. J Clin Invest (2009) 2.94
Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A (2004) 2.89
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes. Proc Natl Acad Sci U S A (2005) 2.85
GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries. Cell Metab (2010) 2.75
A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria. Science (2006) 2.71
Biodiversity and biogeography of phages in modern stromatolites and thrombolites. Nature (2008) 2.70
Zinc sequestration by the neutrophil protein calprotectin enhances Salmonella growth in the inflamed gut. Cell Host Microbe (2012) 2.66
Viral diversity and dynamics in an infant gut. Res Microbiol (2008) 2.63
Metagenomic analysis of stressed coral holobionts. Environ Microbiol (2009) 2.62
The GAAS metagenomic tool and its estimations of viral and microbial average genome size in four major biomes. PLoS Comput Biol (2009) 2.61
Finding novel genes in bacterial communities isolated from the environment. Bioinformatics (2006) 2.55
A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation. J Clin Invest (2006) 2.39
Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci U S A (2004) 2.39
A feed-forward loop amplifies nutritional regulation of PNPLA3. Proc Natl Acad Sci U S A (2010) 2.34
SREBPs: metabolic integrators in physiology and metabolism. Trends Endocrinol Metab (2011) 2.29
Molecular pathogenesis of Salmonella enterica serotype typhimurium-induced diarrhea. Infect Immun (2003) 2.25
Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J Clin Invest (2006) 2.23
Lowering plasma cholesterol levels halts progression of aortic valve disease in mice. Circulation (2009) 2.20
Calcific aortic valve stenosis in old hypercholesterolemic mice. Circulation (2006) 2.13
Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron. Cell Host Microbe (2013) 2.06
Life in the inflamed intestine, Salmonella style. Trends Microbiol (2009) 1.97
Transposases are the most abundant, most ubiquitous genes in nature. Nucleic Acids Res (2010) 1.91
PhiSpy: a novel algorithm for finding prophages in bacterial genomes that combines similarity- and composition-based strategies. Nucleic Acids Res (2012) 1.91
Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice. J Lipid Res (2008) 1.91
The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons. J Biol Chem (2008) 1.91
Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria. Dev Cell (2010) 1.90
Mosaic prophages with horizontally acquired genes account for the emergence and diversification of the globally disseminated M1T1 clone of Streptococcus pyogenes. J Bacteriol (2005) 1.90
Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A (2010) 1.89
Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria. Science (2013) 1.88
Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell (2011) 1.86
Metagenomic analysis indicates that stressors induce production of herpes-like viruses in the coral Porites compressa. Proc Natl Acad Sci U S A (2008) 1.86
Comparative metagenomics reveals host specific metavirulomes and horizontal gene transfer elements in the chicken cecum microbiome. PLoS One (2008) 1.86
Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases. Mol Biol Cell (2005) 1.85
NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. Cancer Res (2010) 1.85
The posttranslational processing of prelamin A and disease. Annu Rev Genomics Hum Genet (2009) 1.81
Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf. J Clin Invest (2004) 1.81
Reversal of hyperlipidemia with a genetic switch favorably affects the content and inflammatory state of macrophages in atherosclerotic plaques. Circulation (2011) 1.79
T cells help to amplify inflammatory responses induced by Salmonella enterica serotype Typhimurium in the intestinal mucosa. Infect Immun (2008) 1.76
Selective coactivator interactions in gene activation by SREBP-1a and -1c. Mol Cell Biol (2004) 1.75
Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice. J Biol Chem (2008) 1.73
Chylomicronemia elicits atherosclerosis in mice--brief report. Arterioscler Thromb Vasc Biol (2009) 1.72
The use of flow cytometry to detect expression of subunits encoded by 11 Salmonella enterica serotype Typhimurium fimbrial operons. Mol Microbiol (2003) 1.71
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity. J Lipid Res (2006) 1.68
Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion. Circulation (2003) 1.68
Interleukin-23 orchestrates mucosal responses to Salmonella enterica serotype Typhimurium in the intestine. Infect Immun (2008) 1.67
Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia. J Lipid Res (2009) 1.67
COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis. Proc Natl Acad Sci U S A (2009) 1.67
Th17 cytokines and the gut mucosal barrier. J Clin Immunol (2010) 1.64
Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway. J Biol Chem (2005) 1.64
Viral communities associated with healthy and bleaching corals. Environ Microbiol (2008) 1.64
Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res (2006) 1.62
SEED servers: high-performance access to the SEED genomes, annotations, and metabolic models. PLoS One (2012) 1.62
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol (2013) 1.61
Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects. Circ Cardiovasc Genet (2010) 1.60
A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells. Proc Natl Acad Sci U S A (2005) 1.59
SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice. J Clin Invest (2008) 1.58
Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression. Gastroenterology (2004) 1.56
Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. Mol Cell Biol (2002) 1.56
Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase. J Biol Chem (2009) 1.54
CsgA is a pathogen-associated molecular pattern of Salmonella enterica serotype Typhimurium that is recognized by Toll-like receptor 2. Mol Microbiol (2005) 1.51
Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2). J Biol Chem (2003) 1.51
Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagy. Cell Metab (2011) 1.50
AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase. J Biol Chem (2008) 1.50
miR-23a promotes the transition from indolent to invasive colorectal cancer. Cancer Discov (2012) 1.49
CD1d function is regulated by microsomal triglyceride transfer protein. Nat Med (2004) 1.49
PGC-1alpha activates CYP7A1 and bile acid biosynthesis. J Biol Chem (2003) 1.49
Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects. J Biol Chem (2005) 1.48
GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer. J Clin Invest (2007) 1.47
Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif. Proc Natl Acad Sci U S A (2009) 1.46
Robotic radical prostatectomy: a technique to reduce pT2 positive margins. Urology (2004) 1.46
Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1. Nucleic Acids Res (2010) 1.44
Compensatory increase in hepatic lipogenesis in mice with conditional intestine-specific Mttp deficiency. J Biol Chem (2005) 1.43
Taxonomic composition and gene content of a methane-producing microbial community isolated from a biogas reactor. J Biotechnol (2008) 1.41