Published in J Biol Chem on January 25, 1990
Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol (2003) 3.03
Decoration of lipopolysaccharide with phosphorylcholine: a phase-variable characteristic of Haemophilus influenzae. Infect Immun (1997) 2.27
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics (2012) 1.98
Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. Microbiol Rev (1996) 1.77
The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity. Mol Biol Cell (2002) 1.63
The mitochondrial outer membrane protein Mas22p is essential for protein import and viability of yeast. Proc Natl Acad Sci U S A (1994) 1.52
Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae. Annu Rev Biochem (2011) 1.51
Coordinate genetic control of yeast fatty acid synthase genes FAS1 and FAS2 by an upstream activation site common to genes involved in membrane lipid biosynthesis. EMBO J (1992) 1.47
Phosphatidylcholine and the CDP-choline cycle. Biochim Biophys Acta (2012) 1.28
The AAPT1 gene of soybean complements a cholinephosphotransferase-deficient mutant of yeast. Plant Cell (1994) 1.11
Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine. Biochem J (1999) 1.10
Cloning, sequencing, and expression in Escherichia coli of the Bacillus subtilis gene for phosphatidylserine synthase. J Bacteriol (1994) 1.08
Primary structures of the wild-type and mutant alleles encoding the phosphatidylglycerophosphate synthase of Escherichia coli. J Bacteriol (1994) 1.04
Phosphatidylcholine synthesis influences the diacylglycerol homeostasis required for SEC14p-dependent Golgi function and cell growth. Mol Biol Cell (2001) 0.97
Regulation of phospholipid synthesis in Saccharomyces cerevisiae by zinc depletion. Biochim Biophys Acta (2006) 0.92
Unraveling the mode of action of the antimalarial choline analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae. Antimicrob Agents Chemother (2004) 0.90
Fluorescent protein tagging as a tool to define the subcellular distribution of proteins in plants. Front Plant Sci (2013) 0.85
Effects of fasting on phosphatidylcholine biosynthesis in hamster liver: regulation of cholinephosphotransferase activity by endogenous argininosuccinate. Biochem J (1993) 0.83
Phospholipid and cation activation of chimaeric choline/ethanolamine phosphotransferases. Biochem J (1996) 0.77
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1990) 0.75
Effects of affirmative action in medical schools. A study of the class of 1975. N Engl J Med (1985) 6.29
Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells. J Biol Chem (1986) 5.78
Functions of sphingolipids and sphingolipid breakdown products in cellular regulation. Science (1989) 4.44
Cloning and expression of multiple protein kinase C cDNAs. Cell (1986) 4.23
Drug prevention in junior high: a multi-site longitudinal test. Science (1990) 4.10
Affirmative action in medical education and its effect on Howard and Meharry: a study of the class of 1975. J Natl Med Assoc (1988) 3.75
Mutants of Escherichia coli defective in membrane phospholipid synthesis: macromolecular synthesis in an sn-glycerol 3-phosphate acyltransferase Km mutant. J Bacteriol (1974) 3.47
The cost and effectiveness of school-based preventive dental care. Am J Public Health (1985) 3.24
Enzymes of glycerolipid synthesis in eukaryotes. Annu Rev Biochem (1980) 3.06
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets. J Biol Chem (1986) 3.05
Preventing adolescent drug use: long-term results of a junior high program. Am J Public Health (1993) 2.75
Protein kinase C activation by diacylglycerol second messengers. Cell (1986) 2.44
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation. J Biol Chem (1989) 2.32
Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses. Science (1987) 2.29
Enzymes of phospholipid metabolism: localization in the cytoplasmic and outer membrane of the cell envelope of Escherichia coli and Salmonella typhimurium. Biochim Biophys Acta (1971) 2.28
The sexual practices of adolescent virgins: genital sexual activities of high school students who have never had vaginal intercourse. Am J Public Health (1996) 2.24
Assembly of phospholipids into cellular membranes: biosynthesis, transmembrane movement and intracellular translocation. Annu Rev Cell Biol (1988) 2.14
Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine. J Biol Chem (1985) 2.11
Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem (1990) 1.99
A mutant of Escherichia coli auxotrophic for organic phosphates: evidence for two defects in inorganic phosphate transport. Mol Gen Genet (1975) 1.98
Two distinct Raf domains mediate interaction with Ras. J Biol Chem (1995) 1.88
Selective changes in microsomal enzymes of triacylglycerol phosphatidylcholine, and phosphatidylethanolamine biosynthesis during differentiation of 3T3-L1 preadipocytes. J Biol Chem (1978) 1.86
Blunt splenic injury in adults: Multi-institutional Study of the Eastern Association for the Surgery of Trauma. J Trauma (2000) 1.86
sn-1,2-Diacylglycerol kinase of Escherichia coli. Purification, reconstitution, and partial amino- and carboxyl-terminal analysis. J Biol Chem (1985) 1.78
Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of the structural gene for L-glycerol 3-phosphate dehydrogenase. J Bacteriol (1974) 1.77
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst. J Biol Chem (1986) 1.77
Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets. J Biol Chem (1985) 1.76
Regulation of macromolecular biosynthesis in a mutant of Escherichia coli defective in membrane phospholipid biosynthesis. Proc Natl Acad Sci U S A (1973) 1.75
Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of sn-glycerol 3-phosphate acyltransferase Km mutants. J Bacteriol (1974) 1.74
sn-Glycerol-3-phosphate auxotrophy of plsB strains of Escherichia coli: evidence that a second mutation, plsX, is required. J Bacteriol (1984) 1.72
Simultaneous polydrug use among teens: prevalence and predictors. J Subst Abuse (1998) 1.68
The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras. J Biol Chem (1994) 1.67
Impact of a high school condom availability program on sexual attitudes and behaviors. Fam Plann Perspect (1998) 1.66
Specificity and mechanism of protein kinase C activation by sn-1,2-diacylglycerols. Proc Natl Acad Sci U S A (1986) 1.63
Effect of phospholipase C hydrolysis of membrane phospholipids on membranous enzymes. J Biol Chem (1972) 1.62
The DNA sequences encoding plsB and dgk loci of Escherichia coli. J Biol Chem (1983) 1.62
Stepping through the drug use sequence: longitudinal scalogram analysis of initiation and regular use. J Abnorm Psychol (1992) 1.62
Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation. Proc Natl Acad Sci U S A (1985) 1.61
Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols. J Biol Chem (1976) 1.58
sn-1,2-Diacylglycerol kinase of Escherichia coli. Mixed micellar analysis of the phospholipid cofactor requirement and divalent cation dependence. J Biol Chem (1986) 1.57
The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site. Proc Natl Acad Sci U S A (1996) 1.54
The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity. Proc Natl Acad Sci U S A (1995) 1.52
Quantitative measurement of sn-1,2-diacylglycerols. Methods Enzymol (1987) 1.50
Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA. Cell (1988) 1.49
Assembly of the endoplasmic reticulum phospholipid bilayer: the phosphatidylcholine transporter. Cell (1985) 1.48
Effect of harvesting methods, growth conditions and growth phase on diacylglycerol levels in cultured human adherent cells. Biochim Biophys Acta (1988) 1.46
Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets. J Biol Chem (1986) 1.42
The decline and fall of the jejunoileal bypass. Surg Gynecol Obstet (1983) 1.39
A clinically detailed risk information system for cost. Health Care Financ Rev (2000) 1.39
Students' acquisition and use of school condoms in a high school condom availability program. Pediatrics (1997) 1.39
Lipid topogenesis. J Lipid Res (1981) 1.36
Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases. J Biol Chem (1986) 1.35
Teenagers and alcohol misuse in the United States: by any definition, it's a big problem. Addiction (1996) 1.33
Protein kinase C contains two phorbol ester binding domains. J Biol Chem (1991) 1.33
Transmembrane movement of phosphatidylglycerol and diacylglycerol sulfhydryl analogues. Biochemistry (1984) 1.32
Microsomal sn-glycerol 3-phosphate and dihydroxyacetone phosphate acyltransferase activities from liver and other tissues. Evidence for a single enzyme catalizing both reactions. Arch Biochem Biophys (1977) 1.32
Distinct patterns of expression of different protein kinase C mRNAs in rat tissues. Cell (1987) 1.31
Triacylglycerol synthesis in isolated fat cells. Evidence that the sn-glycerol-3-phosphate and dihydroxyacetone phosphate acyltransferase activities are dual catalytic functions of a single microsomal enzyme. J Biol Chem (1976) 1.31
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis. J Biol Chem (1985) 1.30
Changes in bioactive lipids, alkylacylglycerol and ceramide, occur in HIV-infected cells. Biochem Biophys Res Commun (1992) 1.29
Acyl carrier protein. XV. Studies of -ketoacyl-acyl carrier protein synthetase. J Biol Chem (1972) 1.27
Amikacin pharmacokinetics in morbidly obese patients. Am J Hosp Pharm (1980) 1.26
Membrane phospholipid synthesis in Escherichia coli. Purification, reconstitution, and characterization of sn-glycerol-3-phosphate acyltransferase. J Biol Chem (1981) 1.23
Protein kinase C activation in mixed micelles. Mechanistic implications of phospholipid, diacylglycerol, and calcium interdependencies. J Biol Chem (1986) 1.23
A phorbol ester binding domain of protein kinase C gamma. Deletion analysis of the Cys2 domain defines a minimal 43-amino acid peptide. J Biol Chem (1994) 1.23
Inhibition of sphingosine kinase in vitro and in platelets. Implications for signal transduction pathways. J Biol Chem (1992) 1.22
Evidence that biosynthesis of phosphatidylethanolamine, phosphatidylcholine, and triacylglycerol occurs on the cytoplasmic side of microsomal vesicles. J Cell Biol (1978) 1.22
Expression of the alpha, beta II, and gamma protein kinase C isozymes in the baculovirus-insect cell expression system. Purification and characterization of the individual isoforms. J Biol Chem (1990) 1.21
Mutants of Escherichia coli defective in membrane phospholipid synthesis. Effects of cessation and reinitiation of phospholipid synthesis on macromolecular synthesis and phospholipid turnover. J Biol Chem (1977) 1.20
Membrane matrix disruption by melittin. Biochim Biophys Acta (1972) 1.20
Noninvasive diagnosis of vascular trauma by duplex ultrasonography. J Vasc Surg (1991) 1.20
Mutants of Escherichia coli defective in membrane phospholipid synthesis. Properties of wild type and Km defective sn-glycerol-3-phosphate acyltransferase activities. J Biol Chem (1975) 1.18
Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. J Biol Chem (1980) 1.18
Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds. Biochemistry (1989) 1.16
sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae. Nucleotide sequence of the EPT1 gene and comparison of the CPT1 and EPT1 gene products. J Biol Chem (1991) 1.16
1,2-Diacylglycerols do not potentiate the action of phospholipases A2 and C in human platelets. Biochem Biophys Res Commun (1984) 1.15
Liberalized screening for blunt carotid and vertebral artery injuries is justified. J Trauma (2001) 1.15
Complications of nonoperative management of blunt hepatic injuries. J Trauma (1992) 1.14
Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways. J Biol Chem (1987) 1.13
Mutants of Saccharomyces cerevisiae defective in sn-1,2-diacylglycerol cholinephosphotransferase. Isolation, characterization, and cloning of the CPT1 gene. J Biol Chem (1987) 1.11
Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity. Biochim Biophys Acta (1996) 1.11
Limited palmitoyl-CoA penetration into microsomal vesicles as evidenced by a highly latent ethanol acyltransferase activity. J Biol Chem (1978) 1.10
Regulation of phospholipid biosynthesis in Escherichia coli. Cloning of the structural gene for the biosynthetic sn-glycerol-3-phosphate dehydrogenase. J Biol Chem (1980) 1.10
Attenuation of sn-1,2-diacylglycerol second messengers. Metabolism of exogenous diacylglycerols by human platelets. J Biol Chem (1986) 1.09
sn-1,2-Diacylglycerol kinase of Escherichia coli. Structural and kinetic analysis of the lipid cofactor dependence. J Biol Chem (1986) 1.08
Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding. Proc Natl Acad Sci U S A (1985) 1.08
The lipid binding, regulatory domain of protein kinase C. A 32-kDa fragment contains the calcium- and phosphatidylserine-dependent phorbol diester binding activity. J Biol Chem (1986) 1.08
Sangivamycin, a nucleoside analogue, is a potent inhibitor of protein kinase C. J Biol Chem (1988) 1.07
A phorbol ester binding domain of protein kinase C gamma. High affinity binding to a glutathione-S-transferase/Cys2 fusion protein. J Biol Chem (1994) 1.07
Lipid biochemistry: functions of glycerolipids and sphingolipids in cellular signaling. FASEB J (1997) 1.06
Membrane phospholipid synthesis in Escherichia coli. Identification of the sn-glycerol-3-phosphate acyltransferase polypeptide as the plsB gene product. J Biol Chem (1980) 1.06
Sphingosine kinase: properties and cellular functions. Adv Lipid Res (1993) 1.06
Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells. J Biol Chem (1988) 1.04
Conjecture versus empirical data: a response to concerns raised about the National Preventive Dentistry Demonstration Program. Am J Public Health (1986) 1.04
sn-1,2-diacylglycerol choline- and ethanolaminephosphotransferases in Saccharomyces cerevisiae. Mixed micellar analysis of the CPT1 and EPT1 gene products. J Biol Chem (1991) 1.03