Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos.

PubWeight™: 1.14‹?› | Rank: Top 10%

🔗 View Article (PMC 3118517)

Published in J Toxicol Environ Health B Crit Rev on January 01, 2011

Authors

Brooke T Mossman1, Morton Lippmann, Thomas W Hesterberg, Karl T Kelsey, Aaron Barchowsky, James C Bonner

Author Affiliations

1: Department of Pathology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA. brooke.mossman@uvm.edu

Articles citing this

Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study. PLoS One (2013) 1.55

Oxidative stress and pulmonary fibrosis. Biochim Biophys Acta (2012) 1.31

Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells. Part Fibre Toxicol (2013) 1.16

New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas. Am J Pathol (2013) 1.15

Molecular basis of asbestos-induced lung disease. Annu Rev Pathol (2013) 1.01

Use of silver nanowires to determine thresholds for fibre length-dependent pulmonary inflammation and inhibition of macrophage migration in vitro. Part Fibre Toxicol (2012) 0.95

Non-neoplastic and neoplastic pleural endpoints following fiber exposure. J Toxicol Environ Health B Crit Rev (2011) 0.94

Quantification of short and long asbestos fibers to assess asbestos exposure: a review of fiber size toxicity. Environ Health (2014) 0.93

Amphibole, but not chrysotile, asbestos induces anti-nuclear autoantibodies and IL-17 in C57BL/6 mice. J Immunotoxicol (2013) 0.90

Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats. J Nanomater (2015) 0.90

New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics. J Toxicol Environ Health B Crit Rev (2012) 0.88

Malignant mesothelioma: development to therapy. J Cell Biochem (2014) 0.85

The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis. Int J Mol Sci (2015) 0.84

Asbestos-induced alveolar epithelial cell apoptosis. The role of endoplasmic reticulum stress response. Am J Respir Cell Mol Biol (2013) 0.84

AKT/mTOR and c-Jun N-terminal kinase signaling pathways are required for chrysotile asbestos-induced autophagy. Free Radic Biol Med (2014) 0.83

Nanoparticles, lung injury, and the role of oxidant stress. Annu Rev Physiol (2013) 0.82

Meeting report: mode(s) of action of asbestos and related mineral fibers. Environ Health Perspect (2011) 0.81

Personal exposure to asbestos and respiratory health of heavy vehicle brake mechanics. J Expo Sci Environ Epidemiol (2014) 0.81

Increased levels of C-C chemokine RANTES in asbestos exposed workers and in malignant mesothelioma patients from an hyperendemic area. PLoS One (2014) 0.80

Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice. Carcinogenesis (2015) 0.79

Lung carcinogenicity of inhaled multi-walled carbon nanotube in rats. Part Fibre Toxicol (2016) 0.79

Extracellular signal-regulated kinase 5 and cyclic AMP response element binding protein are novel pathways inhibited by vandetanib (ZD6474) and doxorubicin in mesotheliomas. Am J Respir Cell Mol Biol (2014) 0.79

Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells. Oncotarget (2016) 0.78

Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice. Am J Respir Cell Mol Biol (2015) 0.77

Biological and environmental interactions of emerging two-dimensional nanomaterials. Chem Soc Rev (2016) 0.76

The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases. Part Fibre Toxicol (2016) 0.75

Quantitative analysis of the role of fiber length on phagocytosis and inflammatory response by alveolar macrophages. Biochim Biophys Acta (2016) 0.75

Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells. Hum Mol Genet (2014) 0.75

Asbestos-Induced Gastrointestinal Cancer: An Update. J Gastrointest Dig Syst (2013) 0.75

The risk of lung cancer after cessation of asbestos exposure in construction workers using pleural malignant mesothelioma as a marker of exposure. J Occup Environ Med (2014) 0.75

Global DNA hypomethylation has no impact on lung function or serum inflammatory and fibrosis cytokines in asbestos-exposed population. Int Arch Occup Environ Health (2017) 0.75

Articles cited by this

(truncated to the top 100)

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 16.54

Asbestos: scientific developments and implications for public policy. Science (1990) 7.06

Asbestos exposure, smoking, and neoplasia. JAMA (1968) 6.25

The effects of the inhalation of asbestos in rats. Br J Cancer (1974) 5.57

Diagnosis and initial management of nonmalignant diseases related to asbestos. Am J Respir Crit Care Med (2004) 5.56

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science (1996) 5.17

Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol (1988) 5.16

Mechanisms in the pathogenesis of asbestosis and silicosis. Am J Respir Crit Care Med (1998) 4.72

Relation of particle dimension to carcinogenicity in amphibole asbestoses and other fibrous minerals. J Natl Cancer Inst (1981) 4.60

Asbestos-related diseases. N Engl J Med (1989) 4.25

Regulation of NADPH oxidases: the role of Rac proteins. Circ Res (2006) 3.16

Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev (2004) 3.14

The estimation of synergy or antagonism. Am J Epidemiol (1976) 2.92

Mass and number of fibres in the pathogenesis of asbestos-related lung disease in rats. Br J Cancer (1978) 2.74

Possible mechanisms to explain dust overloading of the lungs. Fundam Appl Toxicol (1988) 2.65

Chrysotile asbestos inhalation in rats: deposition pattern and reaction of alveolar epithelium and pulmonary macrophages. Am Rev Respir Dis (1981) 2.23

Experimental studies of asbestosis. AMA Arch Ind Hyg Occup Med (1951) 2.22

Asbestos exposure indices. Environ Res (1988) 2.22

Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases. Free Radic Biol Med (2003) 2.13

Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. Am J Respir Cell Mol Biol (2010) 2.04

Mesotheliomas in rats following inoculation with acid-leached chrysotile asbestos and other mineral fibres. Carcinogenesis (1981) 1.94

p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Res (2001) 1.88

Pathology of carcinoma of the lung associated with asbestos exposure. Cancer (1972) 1.82

Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. Am J Pathol (2005) 1.82

Toxicity testing in the 21st century: a vision and a strategy. J Toxicol Environ Health B Crit Rev (2010) 1.81

Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73

An overload hypothesis for pulmonary clearance of UICC amosite fibres inhaled by rats. Br J Ind Med (1983) 1.70

Asbestos dust deposition and retention in rats. Ann N Y Acad Sci (1965) 1.68

Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor. Cancer Res (1996) 1.62

The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis. Antioxid Redox Signal (2008) 1.60

Persistent induction of c-fos and c-jun expression by asbestos. Proc Natl Acad Sci U S A (1993) 1.59

Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice. Am J Pathol (2000) 1.59

Deposition and retention of fibres in the human lung. Ann Occup Hyg (1982) 1.58

Inhalation and injection experiments in rats to test the carcinogenicity of MMMF. Ann Occup Hyg (1987) 1.54

Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2003) 1.53

TNF-alpha receptor knockout mice are protected from the fibroproliferative effects of inhaled asbestos fibers. Am J Pathol (1998) 1.52

Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. Am J Respir Cell Mol Biol (2006) 1.51

Lung particle overload: implications for occupational exposures to particles. Regul Toxicol Pharmacol (1995) 1.49

CpG island methylation and expression of tumour-associated genes in lung carcinoma. Eur J Cancer (2005) 1.46

Kinetics of deposition and clearance of inhaled mineral dusts during chronic exposure. Br J Ind Med (1985) 1.43

Specific inhibitors of platelet-derived growth factor or epidermal growth factor receptor tyrosine kinase reduce pulmonary fibrosis in rats. Am J Pathol (1999) 1.42

Approaches to evaluating the toxicity and carcinogenicity of man-made fibers: summary of a workshop held November 11-13, 1991, Durham, North Carolina. Regul Toxicol Pharmacol (1992) 1.41

Cigarette smoke, asbestos, and small irregular opacities. Am Rev Respir Dis (1984) 1.38

Cytotoxicity of long and short crocidolite asbestos fibers in vitro and in vivo. Cancer Res (1990) 1.37

The interactions of tobacco smoking and other agents in cancer etiology. Epidemiol Rev (1987) 1.36

Tumor necrosis factor-alpha induces transforming growth factor-beta1 expression in lung fibroblasts through the extracellular signal-regulated kinase pathway. Am J Respir Cell Mol Biol (2005) 1.36

Myeloperoxidase produces nitrating oxidants in vivo. J Clin Invest (2002) 1.35

Deposition pattern of inorganic particles at the alveolar level in the lungs of rats and mice. Am Rev Respir Dis (1983) 1.34

The relevance of the rat lung response to particle overload for human risk assessment: a workshop consensus report. Inhal Toxicol (2000) 1.34

Inhaled particulate matter causes expression of nuclear factor (NF)-kappaB-related genes and oxidant-dependent NF-kappaB activation in vitro. Am J Respir Cell Mol Biol (2000) 1.32

Black spots concentrate oncogenic asbestos fibers in the parietal pleura. Thoracoscopic and mineralogic study. Am J Respir Crit Care Med (1996) 1.31

The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destruction. Clin Sci (Lond) (2006) 1.31

Biopersistences of man-made vitreous fibers and crocidolite fibers in rat lungs following short-term exposures. Environ Health Perspect (1994) 1.30

TNF-alpha induces TGF-beta1 expression in lung fibroblasts at the transcriptional level via AP-1 activation. J Cell Mol Med (2009) 1.29

Effects of fiber characteristics on lung deposition, retention, and disease. Environ Health Perspect (1990) 1.26

DNA methylation patterns in lung carcinomas. Semin Cancer Biol (2009) 1.25

Asbestos causes translocation of p65 protein and increases NF-kappa B DNA binding activity in rat lung epithelial and pleural mesothelial cells. Am J Pathol (1997) 1.20

Asbestos content of lung tissue, lymph nodes, and pleural plaques from former shipyard workers. Am Rev Respir Dis (1990) 1.20

Peroxynitrite targets the epidermal growth factor receptor, Raf-1, and MEK independently to activate MAPK. J Biol Chem (2000) 1.19

Progressive lung cell reactions and extracellular matrix production after a brief exposure to asbestos. Am J Pathol (1988) 1.18

Synthetic vitreous fibers: a review of toxicology research and its impact on hazard classification. Crit Rev Toxicol (2001) 1.18

Changes in numbers and dimensions of chrysotile asbestos fibers in lungs of rats following short-term exposure. Exp Lung Res (1984) 1.18

Asbestos-induced lung disease. Environ Health Perspect (1993) 1.17

Cellular and molecular mechanisms of asbestos-induced fibrosis. J Cell Physiol (1999) 1.16

Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung. FASEB J (2006) 1.15

Mechanisms of the combined effect of asbestos and smoking in the etiology of lung cancer. Scand J Work Environ Health (1994) 1.14

Asbestos-derived reactive oxygen species activate TGF-beta1. Lab Invest (2004) 1.14

Interspecies comparisons of particle deposition and mucociliary clearance in tracheobronchial airways. J Toxicol Environ Health (1984) 1.12

Induction of squamous metaplasia in organ cultures of hamster trachea by naturally occurring and synthetic fibers. Cancer Res (1983) 1.11

The sizes, shapes, and mineralogy of asbestos structures that induce lung tumors or mesothelioma in AF/HAN rats following inhalation. Risk Anal (1995) 1.11

EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases. Curr Mol Med (2006) 1.11

K-ras mutations in human adenocarcinoma of the lung: association with smoking and occupational exposure to asbestos. Int J Cancer (1993) 1.10

Rapid activation of PDGF-A and -B expression at sites of lung injury in asbestos-exposed rats. Am J Respir Cell Mol Biol (1997) 1.08

Distribution of transforming growth factor-beta 1, fibronectin, and smooth muscle actin in asbestos-induced pulmonary fibrosis in rats. J Histochem Cytochem (1994) 1.07

Clearance and dimensional changes of crocidolite asbestos fibers isolated from lungs of rats following short-term exposure. Environ Res (1987) 1.07

Time course of chemotactic factor generation and the corresponding macrophage response to asbestos inhalation. Am Rev Respir Dis (1986) 1.07

Iron homeostasis in the lung following asbestos exposure. Antioxid Redox Signal (2008) 1.07

Biopersistence of synthetic vitreous fibers and amosite asbestos in the rat lung following inhalation. Toxicol Appl Pharmacol (1998) 1.06

Lung fibrotic responses to particle exposure. Toxicol Pathol (2007) 1.06

Alterations in gene expression in human mesothelial cells correlate with mineral pathogenicity. Am J Respir Cell Mol Biol (2008) 1.06

Asbestos-induced epithelial changes in organ cultures of hamster trachea: inhibition by retinyl methyl ether. Science (1980) 1.05

Comparative proliferative and histopathologic changes in rat lungs after inhalation of chrysotile or crocidolite asbestos. Toxicol Appl Pharmacol (1996) 1.04

P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis. Am J Respir Cell Mol Biol (2005) 1.03

Deposition of sized glass fibres in the respiratory tract of the rat. Ann Occup Hyg (1980) 1.03

Dose-responsive increases in pulmonary fibrosis after inhalation of asbestos. Am J Respir Crit Care Med (1994) 1.03

Patterns of inflammation, cell proliferation, and related gene expression in lung after inhalation of chrysotile asbestos. Am J Pathol (1995) 1.02

Inhaled asbestos fibers induce p53 expression in the rat lung. Am J Respir Cell Mol Biol (1997) 1.02

Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat. J Clin Invest (1998) 1.01

Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice. Cancer Res (2005) 1.00

The biopersistence of brazilian chrysotile asbestos following inhalation. Inhal Toxicol (2005) 0.99

Selective particle deposition and bronchogenic carcinoma. Environ Res (1978) 0.99

Observations concerning alveolar dust clearance. Ann N Y Acad Sci (1972) 0.99

Influence of asbestos on the uptake of benzo(a)pyrene and DNA alkylation in hamster tracheal epithelial cells. Cancer Res (1983) 0.99

Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases. J Toxicol Environ Health B Crit Rev (2011) 0.98

Deposition, clearance, and translocation of chrysotile asbestos from peripheral and central regions of the rat lung. Environ Res (1992) 0.98

The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos. Cancer Res (2004) 0.98

Identification of specific gene copy number changes in asbestos-related lung cancer. Cancer Res (2006) 0.97

Increased TGF-beta1 in the lungs of asbestos-exposed rats and mice: reduced expression in TNF-alpha receptor knockout mice. J Environ Pathol Toxicol Oncol (2001) 0.97

Asbestos fibers and interferon-gamma up-regulate nitric oxide production in rat alveolar macrophages. Am J Respir Cell Mol Biol (1994) 0.97

Chrysotile as a cause of mesothelioma: an assessment based on epidemiology. Crit Rev Toxicol (2006) 0.97

Articles by these authors

(truncated to the top 100)

DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics (2012) 9.31

Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07

Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model. JAMA (2005) 5.83

Associations between ozone and daily mortality: analysis and meta-analysis. Epidemiology (2005) 4.21

Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2007) 4.01

Model-based clustering of DNA methylation array data: a recursive-partitioning algorithm for high-dimensional data arising as a mixture of beta distributions. BMC Bioinformatics (2008) 3.89

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst (2010) 3.18

MicroRNA responses to cellular stress. Cancer Res (2006) 3.13

Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers. Cancer Res (2007) 2.93

DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J Natl Cancer Inst (2010) 2.87

Time-series analysis of mortality effects of fine particulate matter components in Detroit and Seattle. Environ Health Perspect (2010) 2.82

Inhaled carbon nanotubes reach the subpleural tissue in mice. Nat Nanotechnol (2009) 2.78

Lack of association of alcohol and tobacco with HPV16-associated head and neck cancer. J Natl Cancer Inst (2007) 2.68

A case-control study of smoking and bladder cancer risk: emergent patterns over time. J Natl Cancer Inst (2009) 2.40

Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. Am J Respir Cell Mol Biol (2008) 2.32

A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers. Carcinogenesis (2009) 2.28

Genomic and proteomic profiling of responses to toxic metals in human lung cells. Environ Health Perspect (2003) 2.21

Human papillomavirus type 16 and squamous cell carcinoma of the head and neck. Clin Cancer Res (2002) 2.20

Recommendations for the design and analysis of epigenome-wide association studies. Nat Methods (2013) 2.19

MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin Cancer Res (2009) 2.13

Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res (2010) 2.10

Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility. Carcinogenesis (2005) 2.08

Particle concentrations in inner-city homes of children with asthma: the effect of smoking, cooking, and outdoor pollution. Environ Health Perspect (2003) 2.02

Nightshift work and genome-wide DNA methylation. Chronobiol Int (2014) 2.01

Epigenetic profiling reveals etiologically distinct patterns of DNA methylation in head and neck squamous cell carcinoma. Carcinogenesis (2009) 1.94

DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer. J Clin Oncol (2011) 1.92

Arsenic and cardiovascular disease. Toxicol Sci (2008) 1.90

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox. Arterioscler Thromb Vasc Biol (2010) 1.88

Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival. Oncogene (2004) 1.82

Toxicity testing in the 21st century: a vision and a strategy. J Toxicol Environ Health B Crit Rev (2010) 1.81

Blood-based profiles of DNA methylation predict the underlying distribution of cell types: a validation analysis. Epigenetics (2013) 1.79

Human papillomavirus 16 and head and neck squamous cell carcinoma. Int J Cancer (2007) 1.78

Biomarkers of HPV in head and neck squamous cell carcinoma. Cancer Res (2012) 1.76

Peripheral blood immune cell methylation profiles are associated with nonhematopoietic cancers. Cancer Epidemiol Biomarkers Prev (2012) 1.76

Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung. ACS Nano (2011) 1.74

Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake. PLoS Genet (2010) 1.74

Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Res (2009) 1.73

Pulmonary applications and toxicity of engineered nanoparticles. Am J Physiol Lung Cell Mol Physiol (2008) 1.72

Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Int J Epidemiol (2009) 1.70

Summary of the development of a signature for detection of residual dust from collapse of the World Trade Center buildings. J Expo Sci Environ Epidemiol (2008) 1.69

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68

Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect (2013) 1.68

PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. Hum Pathol (2005) 1.67

Acute respiratory health effects of air pollution on children with asthma in US inner cities. J Allergy Clin Immunol (2008) 1.67

Long-term exposure to ambient fine particulate pollution induces insulin resistance and mitochondrial alteration in adipose tissue. Toxicol Sci (2011) 1.65

Associations between health effects and particulate matter and black carbon in subjects with respiratory disease. Environ Health Perspect (2005) 1.65

The ADH1C polymorphism modifies the risk of squamous cell carcinoma of the head and neck associated with alcohol and tobacco use. Cancer Epidemiol Biomarkers Prev (2005) 1.64

Semi-supervised recursively partitioned mixture models for identifying cancer subtypes. Bioinformatics (2010) 1.63

A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction. Genet Epidemiol (2009) 1.61

Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity. Am J Respir Cell Mol Biol (2007) 1.60

LINE-1 hypomethylation is associated with bladder cancer risk among nonsmoking Chinese. Int J Cancer (2011) 1.56

Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. Free Radic Biol Med (2011) 1.56

High-risk HPV types and head and neck cancer. Int J Cancer (2014) 1.56

Carcinogen exposure and gene promoter hypermethylation in bladder cancer. Carcinogenesis (2005) 1.55

Epigenetic inactivation of the SFRP genes is associated with drinking, smoking and HPV in head and neck squamous cell carcinoma. Int J Cancer (2006) 1.53

Serum IgE, tumor epidermal growth factor receptor expression, and inherited polymorphisms associated with glioma survival. Cancer Res (2006) 1.52

Patterns of gene promoter methylation in squamous cell cancer of the head and neck. Oncogene (2002) 1.49

Diesel exhaust exposure induces angiogenesis. Toxicol Lett (2009) 1.48

The vascular system as a target of metal toxicity. Toxicol Sci (2007) 1.47

Proinflammatory and cytotoxic effects of Mexico City air pollution particulate matter in vitro are dependent on particle size and composition. Environ Health Perspect (2003) 1.45

A population-based study of the Arg399Gln polymorphism in X-ray repair cross- complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma. Cancer Res (2002) 1.45

Molecular features of adult glioma associated with patient race/ethnicity, age, and a polymorphism in O6-methylguanine-DNA-methyltransferase. Cancer Epidemiol Biomarkers Prev (2005) 1.44

Mature microRNA sequence polymorphism in MIR196A2 is associated with risk and prognosis of head and neck cancer. Clin Cancer Res (2010) 1.44

Bladder cancer SNP panel predicts susceptibility and survival. Hum Genet (2009) 1.43

Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer. Cancer Res (2009) 1.43

Biologic effects induced in vitro by PM10 from three different zones of Mexico City. Environ Health Perspect (2002) 1.41

Epigenetic inactivation of SFRP genes and TP53 alteration act jointly as markers of invasive bladder cancer. Cancer Res (2005) 1.40

Ambient air particulate matter exposure and tissue factor expression in atherosclerosis. Inhal Toxicol (2008) 1.40

Promoter hypermethylation is associated with current smoking, age, gender and survival in bladder cancer. Carcinogenesis (2007) 1.40

Single-walled carbon nanotube (SWCNT)-induced interstitial fibrosis in the lungs of rats is associated with increased levels of PDGF mRNA and the formation of unique intercellular carbon structures that bridge alveolar macrophages in situ. Part Fibre Toxicol (2006) 1.39

Peripheral blood DNA methylation profiles are indicative of head and neck squamous cell carcinoma: an epigenome-wide association study. Epigenetics (2012) 1.35

Arsenic stimulates angiogenesis and tumorigenesis in vivo. Toxicol Sci (2003) 1.35

Arsenic-stimulated liver sinusoidal capillarization in mice requires NADPH oxidase-generated superoxide. J Clin Invest (2008) 1.33

Survival following the diagnosis of noninvasive bladder cancer: WHO/International Society of Urological Pathology versus WHO classification systems. J Urol (2007) 1.33

A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. J Natl Cancer Inst (2002) 1.33

Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.33

Microsatellite instability at tetranucleotide repeats in skin and bladder cancer. Oncogene (2002) 1.33

Enabling personal genomics with an explicit test of epistasis. Pac Symp Biocomput (2010) 1.33

Quantitative reconstruction of leukocyte subsets using DNA methylation. Genome Biol (2014) 1.32

DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro Oncol (2011) 1.29

Glutathione S-transferase polymorphisms and the synergy of alcohol and tobacco in oral, pharyngeal, and laryngeal carcinoma. Cancer Epidemiol Biomarkers Prev (2006) 1.29

MicroRNA expression in head and neck cancer associates with alcohol consumption and survival. Carcinogenesis (2009) 1.29

Analgesic and anti-inflammatory drug use and risk of bladder cancer: a population based case control study. BMC Urol (2007) 1.28

Global methylation in exposure biology and translational medical science. Environ Health Perspect (2011) 1.28

Identification of methylated genes associated with aggressive bladder cancer. PLoS One (2010) 1.27

Line region hypomethylation is associated with lifestyle and differs by human papillomavirus status in head and neck squamous cell carcinomas. Cancer Epidemiol Biomarkers Prev (2008) 1.25

DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy. Hum Hered (2007) 1.25

Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res (2006) 1.23

Arsenic stimulates sinusoidal endothelial cell capillarization and vessel remodeling in mouse liver. Hepatology (2007) 1.23

Allergy-related polymorphisms influence glioma status and serum IgE levels. Cancer Epidemiol Biomarkers Prev (2007) 1.22

Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues. Part Fibre Toxicol (2011) 1.22

A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment. ACS Nano (2013) 1.20

Hypermethylation of RASSF1A and BLU tumor suppressor genes in non-small cell lung cancer: implications for tobacco smoking during adolescence. Int J Cancer (2005) 1.20

ERCC1 and ERCC2 polymorphisms and adult glioma. Neuro Oncol (2005) 1.19

The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction. Cancer Res (2002) 1.19

Folic acid-containing supplement consumption during pregnancy and risk for oral clefts: a meta-analysis. Birth Defects Res A Clin Mol Teratol (2007) 1.19

Angiogenic potential of 3-nitro-4-hydroxy benzene arsonic acid (roxarsone). Environ Health Perspect (2008) 1.18

Bacterial lipopolysaccharide enhances PDGF signaling and pulmonary fibrosis in rats exposed to carbon nanotubes. Am J Respir Cell Mol Biol (2009) 1.18

Residual oil combustion: a major source of airborne nickel in New York City. J Expo Sci Environ Epidemiol (2008) 1.18

Polychlorinated biphenyls, cytochrome P450 1A1, and breast cancer risk in the Nurses' Health Study. Cancer Epidemiol Biomarkers Prev (2002) 1.17