Structural neuroimaging of geriatric depression.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 3746760)

Published in Psychiatr Clin North Am on June 01, 2011

Authors

Sophiya Benjamin1, David C Steffens

Author Affiliations

1: Department of Psychiatry, Duke University Medical Center, DHSP, Box 3837, Durham, 27710 NC, USA.

Articles cited by this

Voxel-based morphometry--the methods. Neuroimage (2000) 34.79

Contributions of anterior cingulate cortex to behaviour. Brain (1995) 9.43

The human orbitofrontal cortex: linking reward to hedonic experience. Nat Rev Neurosci (2005) 7.13

'Vascular depression' hypothesis. Arch Gen Psychiatry (1997) 6.59

Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol Psychiatry (2001) 5.11

Hippocampal volume and depression: a meta-analysis of MRI studies. Am J Psychiatry (2004) 5.10

Magnetization transfer in MRI: a review. NMR Biomed (2001) 4.38

Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J Neurosci (1997) 4.00

Lower hippocampal volume in patients suffering from depression: a meta-analysis. Am J Psychiatry (2004) 3.83

Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc Natl Acad Sci U S A (1998) 3.53

Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci U S A (2001) 3.01

MRI-defined vascular depression. Am J Psychiatry (1997) 2.92

Hippocampal volume in geriatric depression. Biol Psychiatry (2000) 2.81

Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiol Aging (1997) 2.66

Brain volume abnormalities in major depressive disorder: a meta-analysis of magnetic resonance imaging studies. Hum Brain Mapp (2009) 2.55

Reduced volume of orbitofrontal cortex in major depression. Biol Psychiatry (2002) 2.53

Anterior cingulate, gyrus rectus, and orbitofrontal abnormalities in elderly depressed patients: an MRI-based parcellation of the prefrontal cortex. Am J Psychiatry (2004) 2.24

Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol Psychiatry (2000) 2.21

Temporal lobe regions on magnetic resonance imaging identify patients with early Alzheimer's disease. Arch Neurol (1993) 2.17

A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects. Am J Psychiatry (2004) 2.12

Clinically defined vascular depression. Am J Psychiatry (1997) 2.06

Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression. Arch Gen Psychiatry (2007) 2.05

Frontal white matter microstructure and treatment response of late-life depression: a preliminary study. Am J Psychiatry (2002) 2.00

Volumetric reduction in left subgenual prefrontal cortex in early onset depression. Biol Psychiatry (2002) 1.94

Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression. Biol Psychiatry (2006) 1.94

Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression. Br J Psychiatry (2005) 1.90

Volumetric analysis of the prefrontal cortex, amygdala, and hippocampus in major depression. Neuropsychopharmacology (2004) 1.82

Dorsolateral prefrontal cortex and anterior cingulate cortex white matter alterations in late-life depression. Biol Psychiatry (2006) 1.73

Severe deep white matter lesions and outcome in elderly patients with major depressive disorder: follow up study. BMJ (1998) 1.73

Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial. Arch Gen Psychiatry (2010) 1.72

Brain morphometric abnormalities in geriatric depression: long-term neurobiological effects of illness duration. Am J Psychiatry (2002) 1.70

Depression-related variation in brain morphology over 3 years: effects of stress? Arch Gen Psychiatry (2008) 1.61

Quantitative cerebral anatomy in depression. A controlled magnetic resonance imaging study. Arch Gen Psychiatry (1993) 1.61

Hippocampal morphology and distinguishing late-onset from early-onset elderly depression. Am J Psychiatry (2007) 1.56

Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects. Biol Psychiatry (2003) 1.55

Late-life depression and microstructural abnormalities in dorsolateral prefrontal cortex white matter. Am J Psychiatry (2004) 1.55

Imaging phenotypes of major depressive disorder: genetic correlates. Neuroscience (2009) 1.49

Diffuse microstructural abnormalities of normal-appearing white matter in late life depression: a diffusion tensor imaging study. Biol Psychiatry (2009) 1.46

White matter hyperintensity progression and late-life depression outcomes. Arch Gen Psychiatry (2003) 1.46

Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Arch Gen Psychiatry (1992) 1.41

Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression. Arch Gen Psychiatry (2005) 1.39

Greater MRI lesion volumes in elderly depressed subjects than in control subjects. Psychiatry Res (2005) 1.39

Reduction of orbital frontal cortex volume in geriatric depression. Biol Psychiatry (2000) 1.38

Hippocampal volume change in depression: late- and early-onset illness compared. Br J Psychiatry (2004) 1.37

Frontal white matter anisotropy and symptom severity of late-life depression: a magnetic resonance diffusion tensor imaging study. J Neurol Neurosurg Psychiatry (2006) 1.34

Hippocampal/amygdala volumes in geriatric depression. Psychol Med (1999) 1.33

Smaller cingulate volumes in unipolar depressed patients. Biol Psychiatry (2006) 1.33

White-matter integrity predicts stroop performance in patients with geriatric depression. Biol Psychiatry (2006) 1.32

A magnetic resonance imaging study of putamen nuclei in major depression. Psychiatry Res (1991) 1.26

Evidence of white matter tract disruption in MRI hyperintensities. Biol Psychiatry (2001) 1.21

Cerebrovascular disease and evolution of depressive symptoms in the cardiovascular health study. Stroke (2002) 1.21

Anatomic evaluation of the orbitofrontal cortex in major depressive disorder. Biol Psychiatry (2004) 1.20

Quantitative magnetic resonance imaging in geriatric depression and primary degenerative dementia. J Affect Disord (1997) 1.19

The vascular depression subtype: evidence of internal validity. Biol Psychiatry (2008) 1.19

Atrophy and high intensity lesions: complementary neurobiological mechanisms in late-life major depression. Neuropsychopharmacology (2000) 1.18

Amygdala volume analysis in female twins with major depression. Biol Psychiatry (2007) 1.18

Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci (1993) 1.17

Cortical and subcortical abnormalities in late-onset depression with history of suicide attempts investigated with MRI and voxel-based morphometry. J Geriatr Psychiatry Neurol (2010) 1.16

Hippocampal atrophy in major depression: a result of depression-induced neurotoxicity? Mol Psychiatry (1996) 1.13

Thresholding in correlation analyses of magnetic resonance functional neuroimaging. Magn Reson Imaging (2003) 1.13

Macromolecular white matter abnormalities in geriatric depression: a magnetization transfer imaging study. Am J Geriatr Psychiatry (2008) 1.13

Incidence of silent cerebral infarction in patients with major depression. Stroke (1993) 1.12

Magnetic-resonance morphometry in patients with major depression. Psychiatry Res (1998) 1.11

Caudate nucleus volumes and genetic determinants of homocysteine metabolism in the prediction of psychomotor speed in older persons with depression. Am J Psychiatry (2002) 1.11

Frontal white matter anisotropy and antidepressant remission in late-life depression. PLoS One (2008) 1.09

Pattern of brain atrophy in elderly patients with depression revealed by voxel-based morphometry. Psychiatry Res (2008) 1.08

Anterior cingulate dysfunction in geriatric depression. Int J Geriatr Psychiatry (2008) 1.07

The hippocampus and depression. Eur Psychiatry (2002) 1.07

Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. Psychol Med (2007) 1.07

Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy. Am J Psychiatry (2002) 1.05

Smaller orbital frontal cortex volumes associated with functional disability in depressed elders. Biol Psychiatry (2003) 1.05

MRI signal hyperintensities in geriatric depression. Am J Psychiatry (1996) 1.04

Research applications of magnetic resonance spectroscopy to investigate psychiatric disorders. Top Magn Reson Imaging (2008) 1.03

White matter microstructural abnormalities in late-life depression. Int Psychogeriatr (2007) 1.03

Biophysical changes in normal-appearing white matter and subcortical nuclei in late-life major depression detected using magnetization transfer. Psychiatry Res (2004) 1.01

Effects of electroconvulsive therapy on frontal white matter in late-life depression: a diffusion tensor imaging study. Neuropsychobiology (2004) 1.01

Anatomical MRI study of subgenual prefrontal cortex in bipolar and unipolar subjects. Neuropsychopharmacology (2002) 1.01

Anatomical MRI study of basal ganglia in major depressive disorder. Psychiatry Res (2003) 1.01

Regional gray matter changes are associated with cognitive deficits in remitted geriatric depression: an optimized voxel-based morphometry study. Biol Psychiatry (2008) 0.99

The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. Am J Geriatr Psychiatry (2010) 0.98

Neuroanatomic substrates of depression in the elderly. J Geriatr Psychiatry Neurol (1993) 0.97

Cortical thickness and voxel-based morphometry in depressed elderly. Eur Neuropsychopharmacol (2010) 0.96

MRI signal hyperintensities and treatment remission of geriatric depression. J Affect Disord (2010) 0.95

White matter integrity of the whole brain is disrupted in first-episode remitted geriatric depression. Neuroreport (2007) 0.92

White matter hyperintensities and chronicity of depression. J Psychiatr Res (2005) 0.90

Structural neuroimaging research methods in geriatric depression. Am J Geriatr Psychiatry (2006) 0.88

Left orbital frontal cortex volume and performance on the benton visual retention test in older depressives and controls. Neuropsychopharmacology (2003) 0.85

Proton magnetic resonance spectroscopy of late-life major depressive disorder. Psychiatry Res (2009) 0.85

Brain metabolites and cognitive function among older depressed and healthy individuals using 2D MR spectroscopy. Neuropsychopharmacology (2004) 0.83

White matter hyperintensities in post-stroke depression: a case control study. J Neurol Neurosurg Psychiatry (2010) 0.82

Effects of antidepressant treatment on N-acetyl aspartate and choline levels in the hippocampus and thalami of post-stroke depression patients: a study using (1)H magnetic resonance spectroscopy. Psychiatry Res (2010) 0.82

Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression. Psychiatry Res (2009) 0.82

Absence of striatal volume differences between depressed subjects with no comorbid medical illness and matched comparison subjects. Am J Psychiatry (1999) 0.80

Articles by these authors

(truncated to the top 100)

Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. JAMA (2002) 6.72

Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med (2008) 5.34

The Aging, Demographics, and Memory Study: study design and methods. Neuroepidemiology (2005) 4.44

Treatment course with antidepressant therapy in late-life depression. Am J Psychiatry (2012) 2.94

Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples. Alzheimers Dement (2006) 2.51

Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry (2008) 2.32

Reducing suicidal ideation in depressed older primary care patients. J Am Geriatr Soc (2006) 2.11

Head injury in early adulthood and the lifetime risk of depression. Arch Gen Psychiatry (2002) 1.97

Psychiatric disease in the twenty-first century: The case for subcortical ischemic depression. Biol Psychiatry (2006) 1.94

Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry (2006) 1.92

Depression treatment preferences in older primary care patients. Gerontologist (2006) 1.92

Provisional diagnostic criteria for depression of Alzheimer disease. Am J Geriatr Psychiatry (2002) 1.75

Greater risk of dementia when spouse has dementia? The Cache County study. J Am Geriatr Soc (2010) 1.73

Dorsolateral prefrontal cortex and anterior cingulate cortex white matter alterations in late-life depression. Biol Psychiatry (2006) 1.73

Support for the vascular depression hypothesis in late-life depression: results of a 2-site, prospective, antidepressant treatment trial. Arch Gen Psychiatry (2010) 1.72

Incidence of dementia and cognitive impairment, not dementia in the United States. Ann Neurol (2011) 1.63

Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc (2010) 1.60

Late-life depression and microstructural abnormalities in dorsolateral prefrontal cortex white matter. Am J Psychiatry (2004) 1.55

Prefrontal neuropsychological predictors of treatment remission in late-life depression. Neuropsychopharmacology (2004) 1.48

Vascular risk factors and cognitive decline among elderly male twins. Neurology (2006) 1.47

Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy. J Clin Psychiatry (2005) 1.47

Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression. Biol Psychiatry (2004) 1.46

White matter hyperintensity progression and late-life depression outcomes. Arch Gen Psychiatry (2003) 1.46

The persistence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry (2004) 1.46

Persistent mild cognitive impairment in geriatric depression. Int Psychogeriatr (2006) 1.45

Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs). Evid Rep Technol Assess (Full Rep) (2007) 1.42

Depressive state- and disease-related alterations in neural responses to affective and executive challenges in geriatric depression. Am J Psychiatry (2008) 1.42

Influence of serotonin transporter promoter region polymorphisms on hippocampal volumes in late-life depression. Arch Gen Psychiatry (2005) 1.39

Greater MRI lesion volumes in elderly depressed subjects than in control subjects. Psychiatry Res (2005) 1.39

Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: correlation with vascular risk factors. AJR Am J Roentgenol (2003) 1.34

Midlife activity predicts risk of dementia in older male twin pairs. Alzheimers Dement (2008) 1.32

Hippocampal volume and antidepressant response in geriatric depression. Int J Geriatr Psychiatry (2002) 1.31

Aging, gender, and the elderly adult brain: an examination of analytical strategies. Neurobiol Aging (2006) 1.30

Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study. Am J Geriatr Psychiatry (2005) 1.23

Profiles of depressive symptoms in older adults diagnosed with major depression: latent cluster analysis. Am J Geriatr Psychiatry (2009) 1.21

A preliminary metabolomic analysis of older adults with and without depression. Int J Geriatr Psychiatry (2007) 1.19

Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry. Twin Res Hum Genet (2006) 1.19

The vascular depression subtype: evidence of internal validity. Biol Psychiatry (2008) 1.19

Amyloid-associated depression: a prodromal depression of Alzheimer disease? Arch Gen Psychiatry (2008) 1.18

The incidence of mental and behavioral disturbances in dementia: the cache county study. J Neuropsychiatry Clin Neurosci (2003) 1.18

Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors. Genet Med (2007) 1.17

Calcium and vitamin D intakes may be positively associated with brain lesions in depressed and nondepressed elders. Nutr Res (2008) 1.16

Neuropsychiatric symptoms and the risk of institutionalization and death: the aging, demographics, and memory study. J Am Geriatr Soc (2011) 1.15

The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. Biol Psychiatry (2006) 1.15

Neurocognitive correlates of response to treatment in late-life depression. Am J Geriatr Psychiatry (2008) 1.15

National Institutes of Health Pathways to Prevention Workshop: the role of opioids in the treatment of chronic pain. Ann Intern Med (2015) 1.12

Localization of age-associated white matter hyperintensities in late-life depression. Prog Neuropsychopharmacol Biol Psychiatry (2003) 1.11

Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study. Am J Geriatr Psychiatry (2006) 1.10

Cholinesterase inhibitors as adjunctive therapy in patients with schizophrenia and schizoaffective disorder: a review and meta-analysis of the literature. CNS Drugs (2010) 1.10

Psychosocial and clinical predictors of unipolar depression outcome in older adults. Int J Geriatr Psychiatry (2002) 1.10

Contribution of depression to cognitive impairment and dementia in older adults. Neurologist (2007) 1.09

Cognitive performance and informant reports in the diagnosis of cognitive impairment and dementia in African Americans and whites. Alzheimers Dement (2009) 1.08

Orbitofrontal cortex volume in late life depression: influence of hyperintense lesions and genetic polymorphisms. Psychol Med (2007) 1.07

Social support and locus of control as predictors of adherence to antidepressant medication in an elderly population. Am J Geriatr Psychiatry (2005) 1.06

Gender differences in the association between religious involvement and depression: the Cache County (Utah) study. J Gerontol B Psychol Sci Soc Sci (2006) 1.06

Reduction of dorsolateral prefrontal cortex gray matter in late-life depression. Psychiatry Res (2011) 1.05

Smaller orbital frontal cortex volumes associated with functional disability in depressed elders. Biol Psychiatry (2003) 1.05

The impact of religious practice and religious coping on geriatric depression. Int J Geriatr Psychiatry (2003) 1.05

The brain-derived neurotrophic factor VAL66MET polymorphism and cerebral white matter hyperintensities in late-life depression. Am J Geriatr Psychiatry (2008) 1.04

Subcortical lesion severity and orbitofrontal cortex volume in geriatric depression. Biol Psychiatry (2003) 1.03

Allelic differences in the brain-derived neurotrophic factor Val66Met polymorphism in late-life depression. Am J Geriatr Psychiatry (2007) 1.02

Hippocampus shape analysis and late-life depression. PLoS One (2008) 1.02

Widespread effects of hyperintense lesions on cerebral white matter structure. AJR Am J Roentgenol (2007) 1.02

Anatomic location and laterality of MRI signal hyperintensities in late-life depression. J Psychosom Res (2002) 1.01

Early parental death and remarriage of widowed parents as risk factors for Alzheimer disease: the Cache County study. Am J Geriatr Psychiatry (2011) 1.00

The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. Am J Geriatr Psychiatry (2010) 0.98

MRI-defined vascular depression: a review of the construct. Int J Geriatr Psychiatry (2010) 0.98

Implementing a disease management intervention for depression in primary care: a random work sampling study. Gen Hosp Psychiatry (2003) 0.97

Quality of life and physical activity associated to lower prevalence of depression in community-dwelling elderly subjects from Sao Paulo. J Affect Disord (2013) 0.96

APOE related hippocampal shape alteration in geriatric depression. Neuroimage (2008) 0.96

Change in stress and social support as predictors of cognitive decline in older adults with and without depression. Int J Geriatr Psychiatry (2011) 0.96

Amygdala volume in late-life depression: relationship with age of onset. Am J Geriatr Psychiatry (2011) 0.96

Time-to-remission from geriatric depression: psychosocial and clinical factors. Am J Geriatr Psychiatry (2002) 0.95

White matter and subcortical gray matter lesion volume changes and late-life depression outcome: a 4-year magnetic resonance imaging study. Int Psychogeriatr (2006) 0.95

The effects of antidepressant medication adherence as well as psychosocial and clinical factors on depression outcome among older adults. Int J Geriatr Psychiatry (2008) 0.95

Differences in brain volumes among males and female hormone-therapy users and nonusers. Psychiatry Res (2006) 0.95

Fiber tract-specific white matter lesion severity Findings in late-life depression and by AGTR1 A1166C genotype. Hum Brain Mapp (2011) 0.94

A three-factor analytic model of the MADRS in geriatric depression. Int J Geriatr Psychiatry (2003) 0.93

Age-dependent reduction of amygdala volume in bipolar disorder. Psychiatry Res (2008) 0.93

Differential patterns of cognitive decline in anterior and posterior white matter hyperintensity progression. Stroke (2010) 0.92

Religion and the presence and severity of depression in older adults. Am J Geriatr Psychiatry (2012) 0.92

Association analysis of the COMT/MTHFR genes and geriatric depression: an MRI study of the putamen. Int J Geriatr Psychiatry (2009) 0.92

Clinically significant depressive symptoms and associated factors in community elderly subjects from Sao Paulo, Brazil. Am J Geriatr Psychiatry (2009) 0.91

Association of five-factor model personality domains and facets with presence, onset, and treatment outcomes of major depression in older adults. Am J Geriatr Psychiatry (2013) 0.91

Functional evidence implicating a novel TOR1A mutation in idiopathic, late-onset focal dystonia. J Med Genet (2009) 0.90

Fruit, vegetable, and antioxidant intakes are lower in older adults with depression. J Acad Nutr Diet (2012) 0.90

Fatigue as a core symptom in major depressive disorder: overview and the role of bupropion. Expert Rev Neurother (2007) 0.90

White matter lesion volumes and caudate volumes in late-life depression. Int J Geriatr Psychiatry (2006) 0.90

Clinical correlates of anxious depression among elderly patients with depression. J Affect Disord (2005) 0.90

Depression, hippocampal volume changes, and cognitive decline in a clinical sample of older depressed outpatients and non-depressed controls. Aging Ment Health (2012) 0.90

Heterogeneity in symptom profiles among older adults diagnosed with major depression. Int Psychogeriatr (2011) 0.90

Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender. Psychiatr Genet (2003) 0.89

Cross-cultural considerations in administering the center for epidemiologic studies depression scale. Gerontology (2010) 0.89

Church attendance and new episodes of major depression in a community study of older adults: the Cache County Study. J Gerontol B Psychol Sci Soc Sci (2008) 0.89

Vascular nutritional correlates of late-life depression. Am J Geriatr Psychiatry (2006) 0.89

The association of psychosocial factors and depression with hypertension among older adults. Int J Geriatr Psychiatry (2003) 0.89

A longitudinal study of differences in late- and early-onset geriatric depression: depressive symptoms and psychosocial, cognitive, and neurological functioning. Aging Ment Health (2012) 0.89

Neural correlates associated with cognitive decline in late-life depression. Am J Geriatr Psychiatry (2012) 0.89

Prevalence and patterns of comorbid cognitive impairment in low vision rehabilitation for macular disease. Arch Gerontol Geriatr (2009) 0.88

Lobar distribution of lesion volumes in late-life depression: the Biomedical Informatics Research Network (BIRN). Neuropsychopharmacology (2005) 0.88