Published in J Proteome Res on June 27, 2011
Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis. Arthritis Rheum (2013) 1.01
The future of NMR metabolomics in cancer therapy: towards personalizing treatment and developing targeted drugs? Metabolites (2013) 0.81
Metabolic responses induced by DNA damage and poly (ADP-ribose) polymerase (PARP) inhibition in MCF-7 cells. Metabolomics (2015) 0.79
Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study. PLoS One (2015) 0.77
1H HR-MAS NMR Based Metabolic Profiling of Cells in Response to Treatment with a Hexacationic Ruthenium Metallaprism as Potential Anticancer Drug. PLoS One (2015) 0.75
Core Canonical Pathways Involved in Developing Human Glioblastoma Multiforme (GBM). Int J Sci Res Sci Eng Technol (2017) 0.75
Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI). Metabolomics (2007) 6.93
Toward interoperable bioscience data. Nat Genet (2012) 4.72
Platelet nitric oxide and superoxide release during the development of nitrate tolerance: effect of supplemental ascorbate. Circulation (2002) 4.60
Chromosome 6p22 locus associated with clinically aggressive neuroblastoma. N Engl J Med (2008) 3.80
MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data. Nucleic Acids Res (2012) 3.32
Mapping the Arabidopsis organelle proteome. Proc Natl Acad Sci U S A (2006) 3.03
The metabolomics standards initiative. Nat Biotechnol (2007) 2.54
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy. Chem Soc Rev (2010) 2.50
Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nat Genet (2009) 2.47
VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. Circ Res (2003) 2.25
Oxygenation and hematocrit dependence of transverse relaxation rates of blood at 3T. Magn Reson Med (2007) 2.22
Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nat Med (2012) 2.13
Proton transfer ratio, lactate, and intracellular pH in acute cerebral ischemia. Magn Reson Med (2007) 2.09
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression. Cancer Res (2011) 2.07
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. FASEB J (2009) 2.05
Proliferating resident microglia after focal cerebral ischaemia in mice. J Cereb Blood Flow Metab (2007) 1.71
Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration. Am J Pathol (2002) 1.62
A clinically integrated curriculum in evidence-based medicine for just-in-time learning through on-the-job training: the EU-EBM project. BMC Med Educ (2007) 1.55
A constrained least-squares approach to the automated quantitation of in vivo ¹H magnetic resonance spectroscopy data. Magn Reson Med (2011) 1.54
MetaboLights: towards a new COSMOS of metabolomics data management. Metabolomics (2012) 1.53
Clinical proton MR spectroscopy in central nervous system disorders. Radiology (2014) 1.53
Metabolic fingerprinting as a diagnostic tool. Pharmacogenomics (2007) 1.51
Proton NMR analysis of plasma is a weak predictor of coronary artery disease. Nat Med (2006) 1.49
Envisioning a learning health care system: the electronic primary care research network, a case study. Ann Fam Med (2012) 1.42
Deletion of btn1, an orthologue of CLN3, increases glycolysis and perturbs amino acid metabolism in the fission yeast model of Batten disease. Mol Biosyst (2010) 1.42
Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death. Cancer Res (2003) 1.38
A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-alpha null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome. Physiol Genomics (2006) 1.34
Quantitative T(1rho) and adiabatic Carr-Purcell T2 magnetic resonance imaging of human occipital lobe at 4 T. Magn Reson Med (2005) 1.32
Harmonising evidence-based medicine teaching: a study of the outcomes of e-learning in five European countries. BMC Med Educ (2008) 1.30
Effects of intracellular pH, blood, and tissue oxygen tension on T1rho relaxation in rat brain. Magn Reson Med (2002) 1.27
High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease. J Biol Chem (2005) 1.27
Effects of hematocrit and oxygen saturation level on blood spin-lattice relaxation. Magn Reson Med (2003) 1.27
Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study. Circulation (2011) 1.26
The effectiveness of a clinically integrated e-learning course in evidence-based medicine: a cluster randomised controlled trial. BMC Med Educ (2009) 1.22
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. Genome Biol (2011) 1.22
Effectiveness of an e-learning course in evidence-based medicine for foundation (internship) training. J R Soc Med (2010) 1.21
Application of partial least squares discriminant analysis to two-dimensional difference gel studies in expression proteomics. Proteomics (2005) 1.20
An integrated functional genomic study of acute phenobarbital exposure in the rat. BMC Genomics (2010) 1.19
Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. Mol Syst Biol (2009) 1.18
Z-spectroscopy with Alternating-Phase Irradiation. J Magn Reson (2010) 1.17
A signal filtering method for improved quantification and noise discrimination in fourier transform ion cyclotron resonance mass spectrometry-based metabolomics data. J Am Soc Mass Spectrom (2009) 1.17
Estimation of the onset time of cerebral ischemia using T1rho and T2 MRI in rats. Stroke (2010) 1.16
Environmental pollution and diabetes: a neglected association. Lancet (2008) 1.15
Early gene therapy-induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T1 in the rotating frame. Cancer Gene Ther (2002) 1.15
The organelle proteome of the DT40 lymphocyte cell line. Mol Cell Proteomics (2009) 1.14
Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient mice. J Cereb Blood Flow Metab (2005) 1.14
A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. PLoS Genet (2010) 1.13
Pathogenic mitochondrial tRNA point mutations: nine novel mutations affirm their importance as a cause of mitochondrial disease. Hum Mutat (2013) 1.12
The Primary Care Research Object Model (PCROM): a computable information model for practice-based primary care research. J Am Med Inform Assoc (2008) 1.12
Quantitative assessment of water pools by T 1 rho and T 2 rho MRI in acute cerebral ischemia of the rat. J Cereb Blood Flow Metab (2008) 1.12
On- and off-resonance T(1rho) MRI in acute cerebral ischemia of the rat. Magn Reson Med (2003) 1.12
How can we teach EBM in clinical practice? An analysis of barriers to implementation of on-the-job EBM teaching and learning. Med Teach (2011) 1.12
A matter of fat: an introduction to lipidomic profiling methods. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 1.11
Quantitative proteomic approach to study subcellular localization of membrane proteins. Nat Protoc (2006) 1.11
Dynamic changes in oxygenation of intracranial tumor and contralateral brain during tumor growth and carbogen breathing: a multisite EPR oximetry with implantable resonators. J Magn Reson (2011) 1.11
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. Free Radic Biol Med (2011) 1.10
Metabolic phenotyping of a model of adipocyte differentiation. Physiol Genomics (2009) 1.10
Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue - a GC-TOFMS based metabolomics study. BMC Genomics (2012) 1.10
A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease. Neurochem Int (2010) 1.10
Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepsy. Epilepsia (2004) 1.10
A comparative metabolomic study of NHR-49 in Caenorhabditis elegans and PPAR-alpha in the mouse. FEBS Lett (2008) 1.08
A metabolomics perspective of human brain tumours. FEBS J (2007) 1.08
Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by high-resolution MAS 1H NMR spectroscopy. J Proteome Res (2006) 1.08
Metabolic profiling detects biomarkers of protein degradation in COPD patients. Eur Respir J (2011) 1.06
Quantitative T(1rho) and magnetization transfer magnetic resonance imaging of acute cerebral ischemia in the rat. J Cereb Blood Flow Metab (2002) 1.06
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. FASEB J (2005) 1.06
Functional imaging in adult and paediatric brain tumours. Nat Rev Clin Oncol (2012) 1.05
A functional analysis of mouse models of cardiac disease through metabolic profiling. J Biol Chem (2004) 1.04
Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation. Proc Natl Acad Sci U S A (2002) 1.04
Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency. J Med Genet (2012) 1.04
Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma. Radiology (2007) 1.03
A unified structural/terminological interoperability framework based on LexEVS: application to TRANSFoRm. J Am Med Inform Assoc (2013) 1.03
Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst (2012) 1.02
Leptin regulates peripheral lipid metabolism primarily through central effects on food intake. Endocrinology (2008) 1.01
B0 dependence of the on-resonance longitudinal relaxation time in the rotating frame (T1rho) in protein phantoms and rat brain in vivo. Magn Reson Med (2004) 1.01
Comparative metabolomics of estrogen receptor positive and estrogen receptor negative breast cancer: alterations in glutamine and beta-alanine metabolism. J Proteomics (2013) 1.01
Correlating tissue outcome with quantitative multiparametric MRI of acute cerebral ischemia in rats. J Cereb Blood Flow Metab (2009) 1.00
Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study. NMR Biomed (2005) 1.00
Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: correlation with cell density. J Magn Reson Imaging (2004) 1.00
Tumour metabolomics in animal models of human cancer. J Proteome Res (2007) 1.00
Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli. J Biol Chem (2011) 1.00
High-resolution magic angle spinning 1H NMR spectroscopy and reverse transcription-PCR analysis of apoptosis in a rat glioma. Anal Chem (2006) 0.99
A quantitative comparison of metabolite signals as detected by in vivo MRS with ex vivo 1H HR-MAS for childhood brain tumours. NMR Biomed (2009) 0.99
Teaching trainers to incorporate evidence-based medicine (EBM) teaching in clinical practice: the EU-EBM project. BMC Med Educ (2009) 0.99
A practical guide to metabolomic profiling as a discovery tool for human heart disease. J Mol Cell Cardiol (2012) 0.98
Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice. Physiol Genomics (2010) 0.97
High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours. Mol Cancer (2009) 0.97
Determination of regional brain temperature using proton magnetic resonance spectroscopy to assess brain-body temperature differences in healthy human subjects. Magn Reson Med (2007) 0.96
Status epilepticus in 12-day-old rats leads to temporal lobe neurodegeneration and volume reduction: a histologic and MRI study. Epilepsia (2006) 0.96
An algorithm for the automated quantitation of metabolites in in vitro NMR signals. Magn Reson Med (2006) 0.96
High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma. NMR Biomed (2005) 0.96
A metabolomics investigation of non-genotoxic carcinogenicity in the rat. J Proteome Res (2013) 0.96
Mutation of nfxB causes global changes in the physiology and metabolism of Pseudomonas aeruginosa. J Proteome Res (2010) 0.96