The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.

PubWeight™: 1.09‹?› | Rank: Top 10%

🔗 View Article (PMC 3160251)

Published in EMBO J on June 14, 2011

Authors

Makhlouf Rabhi1, Olivier Espéli, Annie Schwartz, Bastien Cayrol, A Rachid Rahmouni, Véronique Arluison, Marc Boudvillain

Author Affiliations

1: Centre de Biophysique Moléculaire, CNRS UPR4301, rue Charles Sadron, Orléans Cedex 2, France.

Articles citing this

Hfq and its constellation of RNA. Nat Rev Microbiol (2011) 4.94

RelA protein stimulates the activity of RyhB small RNA by acting on RNA-binding protein Hfq. Proc Natl Acad Sci U S A (2012) 1.54

Cycling of RNAs on Hfq. RNA Biol (2013) 1.22

A role for Rho-dependent polarity in gene regulation by a noncoding small RNA. Genes Dev (2012) 1.05

sRNAs and the virulence of Salmonella enterica serovar Typhimurium. RNA Biol (2012) 1.04

A small RNA activates CFA synthase by isoform-specific mRNA stabilization. EMBO J (2013) 1.02

RNA remodeling by bacterial global regulator CsrA promotes Rho-dependent transcription termination. Genes Dev (2014) 1.00

Transcriptome profiling of Zymomonas mobilis under ethanol stress. Biotechnol Biofuels (2012) 0.98

Hfq-bridged ternary complex is important for translation activation of rpoS by DsrA. Nucleic Acids Res (2013) 0.91

RNA-binding proteins involved in post-transcriptional regulation in bacteria. Front Microbiol (2015) 0.88

Transcription termination controls prophage maintenance in Escherichia coli genomes. Proc Natl Acad Sci U S A (2013) 0.87

Regulation of Transcript Elongation. Annu Rev Microbiol (2015) 0.86

Structural and mechanistic basis of anti-termination of Rho-dependent transcription termination by bacteriophage P4 capsid protein Psu. Nucleic Acids Res (2013) 0.85

sRNA-Mediated Control of Transcription Termination in E. coli. Cell (2016) 0.83

Effects of Hfq on the conformation and compaction of DNA. Nucleic Acids Res (2015) 0.82

Rho and RNase play a central role in FMN riboswitch regulation in Corynebacterium glutamicum. Nucleic Acids Res (2014) 0.81

The RNA chaperone Hfq impacts growth, metabolism and production of virulence factors in Yersinia enterocolitica. PLoS One (2014) 0.81

Post-transcriptional regulator Hfq binds catalase HPII: crystal structure of the complex. PLoS One (2013) 0.79

Insights into transcription termination of Hfq-binding sRNAs of Escherichia coli and characterization of readthrough products. RNA (2015) 0.78

Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation. Nat Commun (2017) 0.78

The Escherichia Coli Hfq Protein: An Unattended DNA-Transactions Regulator. Front Mol Biosci (2016) 0.78

Transcription Elongation Factor NusA Is a General Antagonist of Rho-dependent Termination in Escherichia coli. J Biol Chem (2016) 0.77

ATP-dependent motor activity of the transcription termination factor Rho from Mycobacterium tuberculosis. Nucleic Acids Res (2015) 0.76

Compaction and condensation of DNA mediated by the C-terminal domain of Hfq. Nucleic Acids Res (2017) 0.75

Translational control and Rho-dependent transcription termination are intimately linked in riboswitch regulation. Nucleic Acids Res (2017) 0.75

Articles cited by this

Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol (2006) 40.15

Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature (2005) 8.19

Experimental determination and system level analysis of essential genes in Escherichia coli MG1655. J Bacteriol (2003) 7.32

Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc Natl Acad Sci U S A (1976) 4.93

Cooperation between translating ribosomes and RNA polymerase in transcription elongation. Science (2010) 3.87

Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants. Proc Natl Acad Sci U S A (1992) 3.79

Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals. Proc Natl Acad Sci U S A (2000) 3.59

Hfq is necessary for regulation by the untranslated RNA DsrA. J Bacteriol (2001) 3.54

Hfq structure, function and ligand binding. Curr Opin Microbiol (2007) 3.49

Control of rRNA transcription in Escherichia coli. Microbiol Rev (1995) 3.31

Structure of Escherichia coli Hfq bound to polyriboadenylate RNA. Proc Natl Acad Sci U S A (2009) 3.04

A NusE:NusG complex links transcription and translation. Science (2010) 3.03

Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol (2009) 3.03

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading. Cell (2003) 3.00

Termination factor Rho and its cofactors NusA and NusG silence foreign DNA in E. coli. Science (2008) 2.66

Transcription termination factor rho is an RNA-DNA helicase. Cell (1987) 2.50

Regulator trafficking on bacterial transcription units in vivo. Mol Cell (2009) 2.43

The role of Hfq in bacterial pathogens. Curr Opin Microbiol (2010) 2.40

Small RNA regulators and the bacterial response to stress. Cold Spring Harb Symp Quant Biol (2006) 2.31

An RNA-dependent nucleoside triphosphate phosphohydrolase (ATPase) associated with rho termination factor. Proc Natl Acad Sci U S A (1974) 2.23

Requirement for E. coli NusG protein in factor-dependent transcription termination. Cell (1992) 2.22

Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and rho. Proc Natl Acad Sci U S A (1992) 2.01

Rho directs widespread termination of intragenic and stable RNA transcription. Proc Natl Acad Sci U S A (2009) 2.00

The poly(A) binding protein Hfq protects RNA from RNase E and exoribonucleolytic degradation. Nucleic Acids Res (2003) 2.00

Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription. Genes Dev (1993) 1.93

A rough guide to the non-coding RNA world of Salmonella. Mol Microbiol (2008) 1.89

Two structurally independent domains of E. coli NusG create regulatory plasticity via distinct interactions with RNA polymerase and regulators. J Mol Biol (2009) 1.85

The host factor required for RNA phage Qbeta RNA replication in vitro. Intracellular location, quantitation, and purification by polyadenylate-cellulose chromatography. J Biol Chem (1975) 1.84

Rho-dependent terminators and transcription termination. Microbiology (2006) 1.81

Identification of small RNAs in Mycobacterium tuberculosis. Mol Microbiol (2009) 1.75

An allosteric mechanism of Rho-dependent transcription termination. Nature (2010) 1.73

RNA polymerase elongation factors. Annu Rev Microbiol (2008) 1.73

Interaction of Escherichia coli RNA polymerase with the ribosomal protein S1 and the Sm-like ATPase Hfq. Biochemistry (2003) 1.69

Ribosomal protein S4 is a transcription factor with properties remarkably similar to NusA, a protein involved in both non-ribosomal and ribosomal RNA antitermination. EMBO J (2001) 1.57

Transcription attenuation associated with bacterial repetitive extragenic BIME elements. J Mol Biol (2001) 1.49

Escherichia coli Hfq binds A18 and DsrA domain II with similar 2:1 Hfq6/RNA stoichiometry using different surface sites. Biochemistry (2006) 1.44

Transcription terminates at lambda tR1 in three clusters. Proc Natl Acad Sci U S A (1982) 1.42

Rho-dependent transcription termination at lambda R1 requires upstream sequences. J Biol Chem (1985) 1.35

Regulation of rho-dependent transcription termination by NusG is specific to the Escherichia coli elongation complex. Biochemistry (2000) 1.32

Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq. Nucleic Acids Res (2011) 1.30

Structural Modelling of the Sm-like Protein Hfq from Escherichia coli. J Mol Biol (2002) 1.29

Only a small subset of the horizontally transferred chromosomal genes in Escherichia coli are translated into proteins. Mol Cell Proteomics (2004) 1.20

Physical properties of the Escherichia coli transcription termination factor rho. 1. Association states and geometry of the rho hexamer. Biochemistry (1992) 1.18

NusG alters rho-dependent termination of transcription in vitro independent of kinetic coupling. Gene Expr (1993) 1.15

Dynamic competition of DsrA and rpoS fragments for the proximal binding site of Hfq as a means for efficient annealing. Nucleic Acids Res (2011) 1.06

Specific binding of Escherichia coli ribosomal protein S1 to boxA transcriptional antiterminator RNA. J Bacteriol (1998) 1.05

Mechanism of inhibition of Rho-dependent transcription termination by bacteriophage P4 protein Psu. J Biol Chem (2006) 0.99

Hfq affects mRNA levels independently of degradation. BMC Mol Biol (2010) 0.99

Activation of Rho-dependent transcription termination by NusG. Dependence on terminator location and acceleration of RNA release. J Biol Chem (1999) 0.98

Enhancement of transcription termination factor rho activity with potassium glutamate. J Biol Chem (1991) 0.97

Mutagenesis-based evidence for an asymmetric configuration of the ring-shaped transcription termination factor Rho. J Mol Biol (2010) 0.96

Mutational changes of conserved residues in the Q-loop region of transcription factor Rho greatly reduce secondary site RNA-binding. J Mol Biol (2001) 0.93

An Escherichia coli gene (yaeO) suppresses temperature-sensitive mutations in essential genes by modulating Rho-dependent transcription termination. Mol Microbiol (1998) 0.92

A bacterial transcription terminator with inefficient molecular motor action but with a robust transcription termination function. J Mol Biol (2009) 0.92

Noncanonical interactions in the management of RNA structural blocks by the transcription termination rho helicase. Biochemistry (2007) 0.91

Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions. J Mol Biol (2004) 0.90

Single-gene deletion mutants of Escherichia coli with altered sensitivity to bicyclomycin, an inhibitor of transcription termination factor Rho. J Bacteriol (2011) 0.88

In vivo expression from the RpoS-dependent P1 promoter of the osmotically regulated proU operon in Escherichia coli and Salmonella enterica serovar Typhimurium: activation by rho and hns mutations and by cold stress. J Bacteriol (2001) 0.84

Simple enzymatic assays for the in vitro motor activity of transcription termination factor Rho from Escherichia coli. Methods Mol Biol (2010) 0.83

The protease Lon and the RNA-binding protein Hfq reduce silencing of the Escherichia coli bgl operon by H-NS. J Bacteriol (2004) 0.83

ATP and other nucleotides stabilize the Rho-mRNA complex. Biochemistry (1999) 0.83

Solution structure of YaeO, a Rho-specific inhibitor of transcription termination. J Biol Chem (2007) 0.82

The structure of RNA-free Rho termination factor indicates a dynamic mechanism of transcript capture. J Mol Biol (2010) 0.81

The mechanism of early transcription termination by Rho026. J Mol Biol (1996) 0.80

Articles by these authors

Cooperation between translating ribosomes and RNA polymerase in transcription elongation. Science (2010) 3.87

The MatP/matS site-specific system organizes the terminus region of the E. coli chromosome into a macrodomain. Cell (2008) 2.15

The poly(A) binding protein Hfq protects RNA from RNase E and exoribonucleolytic degradation. Nucleic Acids Res (2003) 2.00

Transcription through the roadblocks: the role of RNA polymerase cooperation. EMBO J (2003) 1.89

Molecular basis for a protein-mediated DNA-bridging mechanism that functions in condensation of the E. coli chromosome. Mol Cell (2012) 1.67

Chromosome structuring limits genome plasticity in Escherichia coli. PLoS Genet (2007) 1.40

Repression by binding of H-NS within the transcription unit. J Biol Chem (2007) 1.08

A stepwise 2'-hydroxyl activation mechanism for the bacterial transcription termination factor Rho helicase. Nat Struct Mol Biol (2009) 1.06

Dynamic competition of DsrA and rpoS fragments for the proximal binding site of Hfq as a means for efficient annealing. Nucleic Acids Res (2011) 1.06

A role for Rho-dependent polarity in gene regulation by a noncoding small RNA. Genes Dev (2012) 1.05

Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains. Nucleic Acids Res (2012) 1.04

Long-range chromosome organization in E. coli: a site-specific system isolates the Ter macrodomain. PLoS Genet (2012) 0.99

Topological insulators inhibit diffusion of transcription-induced positive supercoils in the chromosome of Escherichia coli. Mol Microbiol (2005) 0.98

Sister chromatid interactions in bacteria revealed by a site-specific recombination assay. EMBO J (2012) 0.97

Cellular electron microscopy imaging reveals the localization of the Hfq protein close to the bacterial membrane. PLoS One (2009) 0.96

Mutagenesis-based evidence for an asymmetric configuration of the ring-shaped transcription termination factor Rho. J Mol Biol (2010) 0.96

RNA synthetic biology inspired from bacteria: construction of transcription attenuators under antisense regulation. Phys Biol (2009) 0.94

Nuclear mRNA quality control in yeast is mediated by Nrd1 co-transcriptional recruitment, as revealed by the targeting of Rho-induced aberrant transcripts. Nucleic Acids Res (2010) 0.92

Noncanonical interactions in the management of RNA structural blocks by the transcription termination rho helicase. Biochemistry (2007) 0.91

Influence of substrate composition on the helicase activity of transcription termination factor Rho: reduced processivity of Rho hexamers during unwinding of RNA-DNA hybrid regions. J Mol Biol (2004) 0.90

Transcription termination factor rho can displace streptavidin from biotinylated RNA. J Biol Chem (2007) 0.90

Testing the steric exclusion model for hexameric helicases: substrate features that alter RNA-DNA unwinding by the transcription termination factor Rho. Biochemistry (2006) 0.89

Dual role of boxB RNA motif in the mechanisms of termination/antitermination at the lambda tR1 terminator revealed in vivo. J Mol Biol (2004) 0.87

Transcription termination controls prophage maintenance in Escherichia coli genomes. Proc Natl Acad Sci U S A (2013) 0.87

Transcriptional pausing in vivo: a nascent RNA hairpin restricts lateral movements of RNA polymerase in both forward and reverse directions. J Mol Biol (2005) 0.87

The functional anatomy of an intrinsic transcription terminator. EMBO J (2003) 0.86

Involvement of HFq protein in the post-transcriptional regulation of E. coli bacterial cytoskeleton and cell division proteins. Cell Cycle (2009) 0.86

Limited topological alteration of the T7 RNA polymerase active center at intrinsic termination sites. Biochemistry (2002) 0.84

Polymer modeling of the E. coli genome reveals the involvement of locus positioning and macrodomain structuring for the control of chromosome conformation and segregation. Nucleic Acids Res (2013) 0.84

Simple enzymatic assays for the in vitro motor activity of transcription termination factor Rho from Escherichia coli. Methods Mol Biol (2010) 0.83

RNA remodeling by hexameric RNA helicases. RNA Biol (2010) 0.83

Expression of bacterial Rho factor in yeast identifies new factors involved in the functional interplay between transcription and mRNP biogenesis. Mol Cell Biol (2009) 0.83

Cotranscriptional recruitment of RNA exosome cofactors Rrp47p and Mpp6p and two distinct Trf-Air-Mtr4 polyadenylation (TRAMP) complexes assists the exonuclease Rrp6p in the targeting and degradation of an aberrant messenger ribonucleoprotein particle (mRNP) in yeast. J Biol Chem (2013) 0.82

Let's get 'Fisical' with bacterial nucleoid. Mol Microbiol (2012) 0.81

Translocation of Escherichia coli RNA polymerase against a protein roadblock in vivo highlights a passive sliding mechanism for transcript elongation. Mol Microbiol (2004) 0.81

Phyletic distribution and conservation of the bacterial transcription termination factor Rho. Microbiology (2013) 0.81

Positive regulatory dynamics by a small noncoding RNA: speeding up responses under temperature stress. Mol Biosyst (2012) 0.81

Conformational transition of DNA bound to Hfq probed by infrared spectroscopy. Phys Chem Chem Phys (2010) 0.80

Multidisciplinary perspectives on bacterial genome organization and dynamics. Mol Microbiol (2012) 0.80

Apoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes. Chembiochem (2002) 0.79

Riboregulation of the bacterial actin-homolog MreB by DsrA small noncoding RNA. Integr Biol (Camb) (2015) 0.79

Fate of mRNA extremities generated by intrinsic termination: detailed analysis of reactions catalyzed by ribonuclease II and poly(A) polymerase. Biochimie (2005) 0.78

Auto-assembly of E. coli DsrA small noncoding RNA: Molecular characteristics and functional consequences. RNA Biol (2009) 0.78

Monitoring RNA unwinding by the transcription termination factor Rho from Mycobacterium tuberculosis. Methods Mol Biol (2015) 0.78

Monofunctionally trans-diammine platinum(II)-modified peptide nucleic acid oligomers: a new generation of potential antisense drugs. Chemistry (2002) 0.78

Analysis of helicase-RNA interactions using nucleotide analog interference mapping. Methods Enzymol (2012) 0.77

Auto-assembly as a new regulatory mechanism of noncoding RNA. Cell Cycle (2009) 0.77

[Bacterial chromosome organization]. Med Sci (Paris) (2009) 0.77

Twins, quadruplexes, and more: functional aspects of native and engineered RNA self-assembly in vivo. Front Life Sci (2013) 0.75

Thermodynamics of the beta(2) association in light-harvesting complex I of Rhodospirillum rubrum. Implication of peptide identity in dimer stability. FEBS J (2008) 0.75

Multiple approaches for the investigation of bacterial small regulatory RNAs self-assembly. Methods Mol Biol (2015) 0.75