Published in J Bacteriol on March 01, 2001
A small RNA regulates the expression of genes involved in iron metabolism in Escherichia coli. Proc Natl Acad Sci U S A (2002) 7.99
Identification of novel small RNAs using comparative genomics and microarrays. Genes Dev (2001) 7.65
Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli. Genes Dev (2003) 7.33
Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymerase. Microbiol Mol Biol Rev (2002) 5.60
Deep sequencing analysis of small noncoding RNA and mRNA targets of the global post-transcriptional regulator, Hfq. PLoS Genet (2008) 5.23
Hfq and its constellation of RNA. Nat Rev Microbiol (2011) 4.94
Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. EMBO J (2002) 3.88
Hfq, a new chaperoning role: binding to messenger RNA determines access for small RNA regulator. EMBO J (2004) 3.75
Quantitative characteristics of gene regulation by small RNA. PLoS Biol (2007) 3.35
Host factors in positive-strand RNA virus genome replication. J Virol (2003) 3.28
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Escherichia coli Hfq has distinct interaction surfaces for DsrA, rpoS and poly(A) RNAs. Nat Struct Mol Biol (2004) 2.79
Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon. Genes Dev (2002) 2.75
Coincident Hfq binding and RNase E cleavage sites on mRNA and small regulatory RNAs. RNA (2003) 2.57
A dual function for a bacterial small RNA: SgrS performs base pairing-dependent regulation and encodes a functional polypeptide. Proc Natl Acad Sci U S A (2007) 2.45
Identification of the Hfq-binding site on DsrA RNA: Hfq binds without altering DsrA secondary structure. RNA (2003) 2.31
Small RNA regulators and the bacterial response to stress. Cold Spring Harb Symp Quant Biol (2006) 2.31
The rpoS mRNA leader recruits Hfq to facilitate annealing with DsrA sRNA. RNA (2008) 2.27
Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation. Nat Struct Mol Biol (2009) 2.25
Positive regulation by small RNAs and the role of Hfq. Proc Natl Acad Sci U S A (2010) 2.23
RNA chaperone activity of the Sm-like Hfq protein. EMBO Rep (2003) 2.13
Predicted structure and phyletic distribution of the RNA-binding protein Hfq. Nucleic Acids Res (2002) 2.01
The poly(A) binding protein Hfq protects RNA from RNase E and exoribonucleolytic degradation. Nucleic Acids Res (2003) 2.00
Sm-like proteins in Eubacteria: the crystal structure of the Hfq protein from Escherichia coli. Nucleic Acids Res (2003) 1.91
Hfq modulates the sigmaE-mediated envelope stress response and the sigma32-mediated cytoplasmic stress response in Escherichia coli. J Bacteriol (2006) 1.86
DksA affects ppGpp induction of RpoS at a translational level. J Bacteriol (2002) 1.84
Implication of membrane localization of target mRNA in the action of a small RNA: mechanism of post-transcriptional regulation of glucose transporter in Escherichia coli. Genes Dev (2005) 1.82
Genome-wide detection of novel regulatory RNAs in E. coli. Genome Res (2011) 1.82
Both RNase E and RNase III control the stability of sodB mRNA upon translational inhibition by the small regulatory RNA RyhB. Nucleic Acids Res (2005) 1.80
The challenge of regulation in a minimal photoautotroph: non-coding RNAs in Prochlorococcus. PLoS Genet (2008) 1.74
Signal transduction cascade for regulation of RpoS: temperature regulation of DsrA. J Bacteriol (2001) 1.71
Impact of the RNA chaperone Hfq on the fitness and virulence potential of uropathogenic Escherichia coli. Infect Immun (2008) 1.65
Characterization of the small untranslated RNA RyhB and its regulon in Vibrio cholerae. J Bacteriol (2005) 1.60
The C-terminal domain of Escherichia coli Hfq is required for regulation. Nucleic Acids Res (2007) 1.55
Killing by ampicillin and ofloxacin induces overlapping changes in Escherichia coli transcription profile. Antimicrob Agents Chemother (2004) 1.55
Disruption of small RNA signaling caused by competition for Hfq. Proc Natl Acad Sci U S A (2010) 1.51
Quorum sensing in Escherichia coli is signaled by AI-2/LsrR: effects on small RNA and biofilm architecture. J Bacteriol (2007) 1.47
Unraveling the secret lives of bacteria: use of in vivo expression technology and differential fluorescence induction promoter traps as tools for exploring niche-specific gene expression. Microbiol Mol Biol Rev (2005) 1.45
Spectroscopic observation of RNA chaperone activities of Hfq in post-transcriptional regulation by a small non-coding RNA. Nucleic Acids Res (2007) 1.41
The RNA binding protein Hfq interacts specifically with tRNAs. RNA (2008) 1.35
Constitutive activation of the Escherichia coli Pho regulon upregulates rpoS translation in an Hfq-dependent fashion. J Bacteriol (2003) 1.30
Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq. Nucleic Acids Res (2011) 1.30
Exopolysaccharide sugars contribute to biofilm formation by Salmonella enterica serovar typhimurium on HEp-2 cells and chicken intestinal epithelium. J Bacteriol (2005) 1.28
Genomic SELEX for Hfq-binding RNAs identifies genomic aptamers predominantly in antisense transcripts. Nucleic Acids Res (2010) 1.27
RNase E-dependent processing stabilizes MicX, a Vibrio cholerae sRNA. Mol Microbiol (2007) 1.26
Translational autocontrol of the Escherichia coli hfq RNA chaperone gene. RNA (2005) 1.25
The small noncoding DsrA RNA is an acid resistance regulator in Escherichia coli. J Bacteriol (2004) 1.25
Effect of salt and RNA structure on annealing and strand displacement by Hfq. Nucleic Acids Res (2009) 1.18
Structure and RNA-binding properties of the bacterial LSm protein Hfq. RNA Biol (2013) 1.16
Identification and function of the RNA chaperone Hfq in the Lyme disease spirochete Borrelia burgdorferi. Mol Microbiol (2010) 1.12
Quantifying the sequence-function relation in gene silencing by bacterial small RNAs. Proc Natl Acad Sci U S A (2011) 1.11
The stoichiometry of the Escherichia coli Hfq protein bound to RNA. RNA (2011) 1.10
The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators. EMBO J (2011) 1.09
Hfq affects the expression of the LEE pathogenicity island in enterohaemorrhagic Escherichia coli. Mol Microbiol (2009) 1.08
Target activation by regulatory RNAs in bacteria. FEMS Microbiol Rev (2015) 1.07
Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq. Nucleic Acids Res (2011) 1.05
Translational activation of rpoS mRNA by the non-coding RNA DsrA and Hfq does not require ribosome binding. Nucleic Acids Res (2009) 1.04
The Vibrio cholerae virulence regulatory cascade controls glucose uptake through activation of TarA, a small regulatory RNA. Mol Microbiol (2010) 1.02
RNA helicases: diverse roles in prokaryotic response to abiotic stress. RNA Biol (2012) 1.01
Development and application of a dapB-based in vivo expression technology system to study colonization of rice by the endophytic nitrogen-fixing bacterium Pseudomonas stutzeri A15. Appl Environ Microbiol (2003) 1.01
Artificial trans-encoded small non-coding RNAs specifically silence the selected gene expression in bacteria. Nucleic Acids Res (2011) 1.00
The structures of mutant forms of Hfq from Pseudomonas aeruginosa reveal the importance of the conserved His57 for the protein hexamer organization. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.99
Antagonistic functions between the RNA chaperone Hfq and an sRNA regulate sensitivity to the antibiotic colicin. EMBO J (2013) 0.98
Non-coding sRNAs regulate virulence in the bacterial pathogen Vibrio cholerae. RNA Biol (2012) 0.97
Sm-like protein Hfq: location of the ATP-binding site and the effect of ATP on Hfq-- RNA complexes. Protein Sci (2007) 0.97
Hfq variant with altered RNA binding functions. Nucleic Acids Res (2006) 0.96
Hfq is a regulator of F-plasmid TraJ and TraM synthesis in Escherichia coli. J Bacteriol (2006) 0.96
Cellular electron microscopy imaging reveals the localization of the Hfq protein close to the bacterial membrane. PLoS One (2009) 0.96
Limited role for the DsrA and RprA regulatory RNAs in rpoS regulation in Salmonella enterica. J Bacteriol (2006) 0.95
Honing the message: post-transcriptional and post-translational control in attaching and effacing pathogens. Trends Microbiol (2011) 0.95
Structural flexibility of RNA as molecular basis for Hfq chaperone function. Nucleic Acids Res (2012) 0.95
The archaeal Lsm protein binds to small RNAs. J Biol Chem (2010) 0.94
The small RNA GcvB regulates sstT mRNA expression in Escherichia coli. J Bacteriol (2008) 0.94
Genetic evidence suggests that the intergenic region between pstA and pstB plays a role in the regulation of rpoS translation during phosphate limitation. J Bacteriol (2006) 0.93
An N-terminally truncated RpoS (sigma(S)) protein in Escherichia coli is active in vivo and exhibits normal environmental regulation even in the absence of rpoS transcriptional and translational control signals. J Bacteriol (2002) 0.92
Proteins with RNA chaperone activity: a world of diverse proteins with a common task-impediment of RNA misfolding. Biochem Res Int (2010) 0.92
Structural analysis of full-length Hfq from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.91
Requirement of the CsdA DEAD-box helicase for low temperature riboregulation of rpoS mRNA. RNA Biol (2010) 0.91
Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS. RNA (2013) 0.90
RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Genome Biol (2014) 0.90
The Vibrio cholerae mannitol transporter is regulated posttranscriptionally by the MtlS small regulatory RNA. J Bacteriol (2011) 0.90
Clostridium difficile Hfq can replace Escherichia coli Hfq for most of its function. RNA (2014) 0.85
In vivo expression from the RpoS-dependent P1 promoter of the osmotically regulated proU operon in Escherichia coli and Salmonella enterica serovar Typhimurium: activation by rho and hns mutations and by cold stress. J Bacteriol (2001) 0.84
The protease Lon and the RNA-binding protein Hfq reduce silencing of the Escherichia coli bgl operon by H-NS. J Bacteriol (2004) 0.83
New insight into the structure and function of Hfq C-terminus. Biosci Rep (2015) 0.82
Isoenergetic microarrays to study the structure and interactions of DsrA and OxyS RNAs in two- and three-component complexes. Biochemistry (2011) 0.82
The RNA chaperone Hfq is required for virulence of Bordetella pertussis. Infect Immun (2013) 0.82
nocoRNAc: characterization of non-coding RNAs in prokaryotes. BMC Bioinformatics (2011) 0.82
Impact of Hfq on the Bacillus subtilis transcriptome. PLoS One (2014) 0.81
Turn-over of the small non-coding RNA RprA in E. coli is influenced by osmolarity. Mol Genet Genomics (2010) 0.81
The small RNA SgrS: roles in metabolism and pathogenesis of enteric bacteria. Front Cell Infect Microbiol (2014) 0.81
Controlled expression of an rpoS antisense RNA can inhibit RpoS function in Escherichia coli. Antimicrob Agents Chemother (2003) 0.81
Diverse mechanisms of post-transcriptional repression by the small RNA regulator of glucose-phosphate stress. Mol Microbiol (2015) 0.80
Characterization of MicA interactions suggests a potential novel means of gene regulation by small non-coding RNAs. Nucleic Acids Res (2013) 0.78
Duplex formation between the sRNA DsrA and rpoS mRNA is not sufficient for efficient RpoS synthesis at low temperature. RNA Biol (2013) 0.78
Modification of the RpoS network with a synthetic small RNA. Nucleic Acids Res (2013) 0.77
In vivo characterization of an Hfq protein encoded by the Bacillus anthracis virulence plasmid pXO1. BMC Microbiol (2017) 0.75
Crystal structure and RNA-binding properties of an Hfq homolog from the deep-branching Aquificae: conservation of the lateral RNA-binding mode. Acta Crystallogr D Struct Biol (2017) 0.75
Hfq assists small RNAs in binding to the coding sequence of ompD mRNA and in rearranging its structure. RNA (2016) 0.75
Systematic characterization of artificial small RNA-mediated inhibition of Escherichia coli growth. RNA Biol (2016) 0.75
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