Published in Biochem Biophys Res Commun on August 31, 1990
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Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection. Proc Natl Acad Sci U S A (1989) 1.32
Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes. Mol Med (1995) 1.28
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Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes. J Immunol (2001) 1.23
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Autoantibodies against the insulin receptor recognize the insulin binding subunits of an oligomeric receptor. Diabetes (1981) 1.18
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The effect of solubilization on the properties of the insulin receptor of human placental membranes. Endocrinology (1978) 1.15
Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes. Diabetes (1989) 1.14
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Impaired yield, phenotype, and function of monocyte-derived dendritic cells in humans at risk for insulin-dependent diabetes. J Immunol (1998) 1.13
Increase in remission rate in newly diagnosed type I diabetic subjects treated with azathioprine. Diabetes (1985) 1.13
Overview: the major histocompatibility complex and insulin dependent diabetes mellitus. Baillieres Clin Endocrinol Metab (1991) 1.11
Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease. Mol Med (1995) 1.10
Regulation of insulin receptors in normal and abnormal physiology in humans. Adv Intern Med (1979) 1.10
Direct evidence for the expression of multiple endogenous retroviruses in the synovial compartment in rheumatoid arthritis. Arthritis Rheum (1997) 1.08
MHCPEP, a database of MHC-binding peptides: update 1996. Nucleic Acids Res (1997) 1.07
HLA antigens and age at diagnosis of insulin-dependent diabetes mellitus. Hum Immunol (1995) 1.07
Lack of association between duration of breast-feeding or introduction of cow's milk and development of islet autoimmunity. Diabetes (1999) 1.06
Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus. Science (1996) 1.06
The human placenta contains two distinct binding and immunoreactive species of insulin-like growth factor-I receptors. J Biol Chem (1985) 1.06
Interferon-gamma enhances the expression of the major histocompatibility class I antigens on mouse pancreatic beta cells. Diabetes (1985) 1.06
Insulin binding leads to the formation of covalent (-S-S-) hormone receptor complexes. J Biol Chem (1982) 1.04
Laminin-1 promotes differentiation of fetal mouse pancreatic beta-cells. Diabetes (1999) 1.04
IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse. J Immunol (1988) 1.04
The potential roles of endogenous retroviruses in autoimmunity. Immunol Rev (1996) 1.04
Cloning and partial nucleotide sequence of human glutamic acid decarboxylase cDNA from brain and pancreatic islets. Biochem Biophys Res Commun (1991) 1.03
High level of concordance between assays for glutamic acid decarboxylase antibodies. The First International Glutamic Acid Decarboxylase Antibody Workshop. Diabetes (1994) 1.03
Molecular pathology of type 1 diabetes. Mol Biol Med (1990) 1.00
Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha. Mol Endocrinol (1988) 0.99
Cytokine-based human whole blood assay for the detection of antigen-reactive T cells. J Immunol Methods (1995) 0.98
Heterogeneity of the insulin-receptor interaction in lipoatropic diabetes. J Clin Endocrinol Metab (1981) 0.97
Reduction in insulitis following administration of IFN-gamma and TNF-alpha in the NOD mouse. J Autoimmun (1991) 0.97
Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific. Clin Immunol (2001) 0.97
T-cell antigen receptor transmembrane peptides modulate T-cell function and T cell-mediated disease. Nat Med (1997) 0.96
Retroviral superantigens and type 1 diabetes mellitus. Cell (1998) 0.96
Structural differences between insulin and somatomedin-C/insulin-like growth factor-1 receptors revealed by autoantibodies to the insulin receptor. Biochem Biophys Res Commun (1982) 0.96
Glutamic acid decarboxylase autoantibodies in preclinical insulin-dependent diabetes. Proc Natl Acad Sci U S A (1992) 0.96
Reovirus infection enhances expression of class I MHC proteins on human beta-cell and rat RINm5F cell. Diabetes (1988) 0.96
Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat. Endocrinology (1993) 0.95
The beta cell in autoimmune diabetes: many mechanisms and pathways of loss. Trends Endocrinol Metab (2001) 0.94
Mucosal antigen primes diabetogenic cytotoxic T-lymphocytes regardless of dose or delivery route. Diabetes (2001) 0.94
Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop. Diabetes (2001) 0.94
Identification of pancreatic beta cell-related genes by representational difference analysis. Endocrinology (1997) 0.94
Fuzzy neural network-based prediction of the motif for MHC class II binding peptides. J Biosci Bioeng (2001) 0.94
IgG subclass antibodies to glutamic acid decarboxylase and risk for progression to clinical insulin-dependent diabetes. Hum Immunol (1998) 0.93
The A-chain of insulin is a hot-spot for CD4+ T cell epitopes in human type 1 diabetes. Clin Exp Immunol (2009) 0.93
An atypical insulin receptor with high affinity for insulin-like growth factors copurified with placental insulin receptors. Proc Natl Acad Sci U S A (1986) 0.93
Evidence that macrophages are required for T-cell infiltration and rejection of fetal pig pancreas xenografts in nonobese diabetic mice. Transplantation (1998) 0.93
Precipitation of the thyrotropin receptor and identification of thyroid autoantigens using Graves' disease immunoglobulins. J Clin Invest (1984) 0.93
Overexpression of class I major histocompatibility complex accompanies insulitis in the non-obese diabetic mouse and is prevented by anti-interferon-gamma antibody. Diabetologia (1991) 0.92
The Melbourne Pre-Diabetes Study: prediction of type 1 diabetes mellitus using antibody and metabolic testing. Med J Aust (1998) 0.92
Antitopoisomerase I monoclonal autoantibodies from scleroderma patients and tight skin mouse interact with similar epitopes. J Exp Med (1992) 0.92
MHCPEP--a database of MHC-binding peptides: update 1995. Nucleic Acids Res (1996) 0.92
Innate and adaptive immune responses to nonvascular xenografts: evidence that macrophages are direct effectors of xenograft rejection. J Immunol (2001) 0.92
Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model. Immunol Rev (2000) 0.91
Novel strategy for identification of candidate cytotoxic T-cell epitopes from human preproinsulin. Tissue Antigens (2003) 0.90
Mapping of multiple B cell epitopes on the 70-kilodalton autoantigen of the U1 ribonucleoprotein complex. J Immunol (1990) 0.90
Disulfide exchange between insulin and its receptor. A possible post-binding step in insulin action. J Biol Chem (1983) 0.90
Changes in insulin-receptor structure associated with trypsin-induced activation of the receptor tyrosine kinase. Biochem J (1991) 0.90
Factors predicting residual beta-cell function in the first year after diagnosis of childhood type 1 diabetes. Diabetes Res Clin Pract (1991) 0.89
Calcium-dependence of insulin receptor phosphorylation. Biochem J (1983) 0.89
Vascularized tissue-engineered chambers promote survival and function of transplanted islets and improve glycemic control. FASEB J (2006) 0.89
Association of HLA-DQw3 (TA10-) with type I diabetes occurs with DR3/4 but not DR1/4 patients. Diabetes (1988) 0.89
Strategies for identifying and predicting islet autoantigen T-cell epitopes in insulin-dependent diabetes mellitus. Ann Med (1997) 0.89
Nonimmune thyroid destruction results from transgenic overexpression of an allogeneic major histocompatibility complex class I protein. Mol Cell Biol (1993) 0.89
HLA-DRB1*0401 is associated with susceptibility to insulin-dependent diabetes mellitus independently of the DQB1 locus. Eur J Immunogenet (1995) 0.88
Rapid improvement in visual field defects following bromocriptine treatment of patients with non-functioning pituitary adenomas. Clin Endocrinol (Oxf) (1986) 0.88
A new view of the beta cell as an antigen-presenting cell and immunogenic target. J Autoimmun (1990) 0.88
Regulation of laminin 1-induced pancreatic beta-cell differentiation by alpha6 integrin and alpha-dystroglycan. Mol Med (2001) 0.88
Radioimmunoassay of the insulin receptor: a new probe of receptor structure and function. Science (1979) 0.87