Raul Andino

Author PubWeight™ 86.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature 2005 6.78
2 Short interfering RNA confers intracellular antiviral immunity in human cells. Nature 2002 5.27
3 The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster. Genes Dev 2006 4.26
4 miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell 2010 4.07
5 Quasispecies theory and the behavior of RNA viruses. PLoS Pathog 2010 3.19
6 Engineering attenuated virus vaccines by controlling replication fidelity. Nat Med 2008 3.01
7 The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol 2006 2.83
8 High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing. Proc Natl Acad Sci U S A 2013 2.44
9 Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. J Biol Chem 2005 2.40
10 Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia. PLoS One 2011 2.23
11 Antiviral immunity in Drosophila requires systemic RNA interference spread. Nature 2009 2.15
12 Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches. J Virol 2005 1.98
13 Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines. Cell Host Microbe 2008 1.94
14 Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance. Genes Dev 2007 1.87
15 Nucleic acid-based immune system: the antiviral potential of mammalian RNA silencing. J Virol 2003 1.81
16 Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications. Virus Res 2005 1.81
17 Ribavirin's antiviral mechanism of action: lethal mutagenesis? J Mol Med (Berl) 2001 1.59
18 Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA. J Virol 2008 1.58
19 Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila. Nat Struct Mol Biol 2010 1.54
20 The role of mutational robustness in RNA virus evolution. Nat Rev Microbiol 2013 1.54
21 Poliovirus pathogenesis in a new poliovirus receptor transgenic mouse model: age-dependent paralysis and a mucosal route of infection. J Gen Virol 2002 1.46
22 Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. J Gen Virol 2006 1.39
23 Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus. Cell Host Microbe 2012 1.32
24 Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin. Microbes Infect 2002 1.29
25 The silent treatment: RNAi as a defense against virus infection in mammals. Trends Biotechnol 2006 1.27
26 Rationalizing the development of live attenuated virus vaccines. Nat Biotechnol 2010 1.26
27 An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis. PLoS Pathog 2010 1.14
28 The poliovirus 2C cis-acting replication element-mediated uridylylation of VPg is not required for synthesis of negative-sense genomes. J Gen Virol 2003 1.13
29 Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses. Biochemistry 2004 1.08
30 Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element. Nucleic Acids Res 2006 1.05
31 The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell protein. J Virol 2004 1.04
32 Single-cell analysis uncovers extensive biological noise in poliovirus replication. J Virol 2014 1.02
33 Non-specific dsRNA-mediated antiviral response in the honey bee. PLoS One 2013 1.00
34 Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex. J Cell Sci 2007 1.00
35 Identification and manipulation of the molecular determinants influencing poliovirus recombination. PLoS Pathog 2013 0.98
36 Exploring the fitness landscape of an RNA virus by using a universal barcode microarray. J Virol 2011 0.97
37 Hsp90 inhibitors exhibit resistance-free antiviral activity against respiratory syncytial virus. PLoS One 2013 0.93
38 Extending the family of UNCG-like tetraloop motifs: NMR structure of a CACG tetraloop from coxsackievirus B3. Biochemistry 2003 0.92
39 RNA interference-mediated intrinsic antiviral immunity in invertebrates. Curr Top Microbiol Immunol 2013 0.92
40 NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA. Biochemistry 2004 0.92
41 A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrob Agents Chemother 2008 0.91
42 Manganese-dependent polioviruses caused by mutations within the viral polymerase. J Virol 2003 0.90
43 Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2. J Biol Chem 2004 0.89
44 Poliovirus vaccine strains as mucosal vaccine vectors and their potential use to develop an AIDS vaccine. Adv Drug Deliv Rev 2004 0.89
45 RNA silencing in viral infections: insights from poliovirus. Virus Res 2004 0.85
46 StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase. BMC Bioinformatics 2011 0.83
47 Global RNA structure analysis of poliovirus identifies a conserved RNA structure involved in viral replication and infectivity. J Virol 2013 0.81
48 Closing the gap: the challenges in converging theoretical, computational, experimental and real-life studies in virus evolution. Curr Opin Virol 2012 0.81
49 An enhanced single base extension technique for the analysis of complex viral populations. PLoS One 2009 0.80
50 Studies towards the potential of poliovirus as a vector for the expression of HPV 16 virus-like-particles. FEMS Immunol Med Microbiol 2002 0.79
51 RNAi puts a lid on virus replication. Nat Biotechnol 2003 0.79
52 Slicer activity in Drosophila melanogaster S2 extract. Methods Mol Biol 2011 0.78
53 Exploring RNA virus replication in Xenopus oocytes. Methods Mol Biol 2006 0.78
54 Poliovirus: generation, quantification, propagation, purification, and storage. Curr Protoc Microbiol 2013 0.77
55 Poliovirus: generation and characterization of mutants. Curr Protoc Microbiol 2013 0.76
56 RNA structure analysis of viruses using SHAPE. Curr Protoc Microbiol 2013 0.75
57 RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence. Cell Host Microbe 2017 0.75