Published in J Biol Chem on August 24, 2004
Cellular protein modification by poliovirus: the two faces of poly(rC)-binding protein. J Virol (2007) 1.51
Regulation of abiotic stress signalling by Arabidopsis C-terminal domain phosphatase-like 1 requires interaction with a k-homology domain-containing protein. PLoS One (2013) 1.47
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem (2008) 1.20
Altered interactions between stem-loop IV within the 5' noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: effects on IRES-mediated translation and viral infectivity. Virology (2009) 1.01
The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation. Virology (2008) 1.01
Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res (2007) 0.99
Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation. RNA (2011) 0.85
Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature (2005) 6.78
Short interfering RNA confers intracellular antiviral immunity in human cells. Nature (2002) 5.27
The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster. Genes Dev (2006) 4.26
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell (2010) 4.07
Quasispecies theory and the behavior of RNA viruses. PLoS Pathog (2010) 3.19
Engineering attenuated virus vaccines by controlling replication fidelity. Nat Med (2008) 3.01
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol (2006) 2.83
DOCK 6: combining techniques to model RNA-small molecule complexes. RNA (2009) 2.75
High-throughput DNA sequencing errors are reduced by orders of magnitude using circle sequencing. Proc Natl Acad Sci U S A (2013) 2.44
Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. J Biol Chem (2005) 2.40
Temporal analysis of the honey bee microbiome reveals four novel viruses and seasonal prevalence of known viruses, Nosema, and Crithidia. PLoS One (2011) 2.23
Antiviral immunity in Drosophila requires systemic RNA interference spread. Nature (2009) 2.15
Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches. J Virol (2005) 1.98
Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov (2008) 1.95
Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines. Cell Host Microbe (2008) 1.94
The design and characterization of two proteins with 88% sequence identity but different structure and function. Proc Natl Acad Sci U S A (2007) 1.91
Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance. Genes Dev (2007) 1.87
A minimal sequence code for switching protein structure and function. Proc Natl Acad Sci U S A (2009) 1.83
Nucleic acid-based immune system: the antiviral potential of mammalian RNA silencing. J Virol (2003) 1.81
Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications. Virus Res (2005) 1.81
A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A (2002) 1.79
Mutational tipping points for switching protein folds and functions. Structure (2012) 1.74
Ribavirin's antiviral mechanism of action: lethal mutagenesis? J Mol Med (Berl) (2001) 1.59
Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA. J Virol (2008) 1.58
Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila. Nat Struct Mol Biol (2010) 1.54
The role of mutational robustness in RNA virus evolution. Nat Rev Microbiol (2013) 1.54
Poliovirus pathogenesis in a new poliovirus receptor transgenic mouse model: age-dependent paralysis and a mucosal route of infection. J Gen Virol (2002) 1.46
NMR structures of two designed proteins with high sequence identity but different fold and function. Proc Natl Acad Sci U S A (2008) 1.41
Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis. J Gen Virol (2006) 1.39
Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus. PLoS One (2013) 1.38
The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion. J Biol Chem (2003) 1.35
Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage. Proc Natl Acad Sci U S A (2008) 1.35
Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. J Biol Chem (2003) 1.33
Codon usage determines the mutational robustness, evolutionary capacity, and virulence of an RNA virus. Cell Host Microbe (2012) 1.32
Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. Chem Biol (2002) 1.30
Implications of high RNA virus mutation rates: lethal mutagenesis and the antiviral drug ribavirin. Microbes Infect (2002) 1.29
The silent treatment: RNAi as a defense against virus infection in mammals. Trends Biotechnol (2006) 1.27
Rationalizing the development of live attenuated virus vaccines. Nat Biotechnol (2010) 1.26
Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry (2002) 1.24
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Cancer Cell (2010) 1.22
NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126. Proc Natl Acad Sci U S A (2003) 1.22
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem (2008) 1.20
Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A. J Biol Chem (2005) 1.19
NMR-based characterization of phenothiazines as a RNA binding scaffold. J Am Chem Soc (2004) 1.17
An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis. PLoS Pathog (2010) 1.14
The poliovirus 2C cis-acting replication element-mediated uridylylation of VPg is not required for synthesis of negative-sense genomes. J Gen Virol (2003) 1.13
Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses. Biochemistry (2004) 1.08
Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity. Biochemistry (2006) 1.07
Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening. Chem Biol (2002) 1.06
NMR of membrane proteins in micelles and bilayers: the FXYD family proteins. Methods (2007) 1.05
Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element. Nucleic Acids Res (2006) 1.05
The poliovirus replication machinery can escape inhibition by an antiviral drug that targets a host cell protein. J Virol (2004) 1.04
Three-dimensional paper-based electrochemiluminescence immunodevice for multiplexed measurement of biomarkers and point-of-care testing. Biomaterials (2011) 1.04
Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets. J Chem Inf Model (2008) 1.04
Single-cell analysis uncovers extensive biological noise in poliovirus replication. J Virol (2014) 1.02
Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides. J Am Chem Soc (2011) 1.02
PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis. Brain Res Mol Brain Res (2004) 1.02
Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab (2006) 1.01
Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA. Chem Biol (2006) 1.01
Non-specific dsRNA-mediated antiviral response in the honey bee. PLoS One (2013) 1.00
Correlation of gene and protein structures in the FXYD family proteins. J Mol Biol (2005) 1.00
Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex. J Cell Sci (2007) 1.00
Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res (2007) 0.99
NMR structure of the full-length linear dimer of stem-loop-1 RNA in the HIV-1 dimer initiation site. J Biol Chem (2006) 0.99
Identification and manipulation of the molecular determinants influencing poliovirus recombination. PLoS Pathog (2013) 0.98
27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: a novel metabolic pathway. Steroids (2003) 0.97
Exploring the fitness landscape of an RNA virus by using a universal barcode microarray. J Virol (2011) 0.97
Staphylococcus epidermidis in the human skin microbiome mediates fermentation to inhibit the growth of Propionibacterium acnes: implications of probiotics in acne vulgaris. Appl Microbiol Biotechnol (2013) 0.96
Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets. DNA Cell Biol (2004) 0.96
Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Res (2007) 0.96
High-resolution NMR structure of an AT-rich DNA sequence. J Biomol NMR (2002) 0.96
Paper-based chemiluminescence ELISA: lab-on-paper based on chitosan modified paper device and wax-screen-printing. Biosens Bioelectron (2011) 0.96
Hsp90 inhibitors exhibit resistance-free antiviral activity against respiratory syncytial virus. PLoS One (2013) 0.93
Using offset recombinant polymerase chain reaction to identify functional determinants in a common family of bacterial albumin binding domains. Biochemistry (2006) 0.93
Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab (2010) 0.93
Extending the family of UNCG-like tetraloop motifs: NMR structure of a CACG tetraloop from coxsackievirus B3. Biochemistry (2003) 0.92
Discovery of ligands for a novel target, the human telomerase RNA, based on flexible-target virtual screening and NMR. J Med Chem (2008) 0.92
NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA. Biochemistry (2004) 0.92
RNA interference-mediated intrinsic antiviral immunity in invertebrates. Curr Top Microbiol Immunol (2013) 0.92
Slow conformational dynamics in the hamster prion protein. Biochemistry (2004) 0.92
In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR. Magn Reson Med (2002) 0.91
Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel. Biochemistry (2010) 0.91
A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrob Agents Chemother (2008) 0.91
Manganese-dependent polioviruses caused by mutations within the viral polymerase. J Virol (2003) 0.90
Nuclear magnetic resonance structural studies of membrane proteins in micelles and bilayers. Methods Mol Biol (2007) 0.90
Characterization of novel selective H1-antihistamines for clinical evaluation in the treatment of insomnia. J Med Chem (2009) 0.90
3D origami-based multifunction-integrated immunodevice: low-cost and multiplexed sandwich chemiluminescence immunoassay on microfluidic paper-based analytical device. Lab Chip (2012) 0.90
An artificially evolved albumin binding module facilitates chemical shift epitope mapping of GA domain interactions with phylogenetically diverse albumins. Protein Sci (2007) 0.89
Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding. Nucleic Acids Res (2007) 0.89
Poliovirus vaccine strains as mucosal vaccine vectors and their potential use to develop an AIDS vaccine. Adv Drug Deliv Rev (2004) 0.89
Detecting ligand binding to a small RNA target via saturation transfer difference NMR experiments in D(2)O and H(2)O. J Am Chem Soc (2002) 0.88
Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices. Anesthesiology (2007) 0.88
Electrochemical immunoassay on a 3D microfluidic paper-based device. Chem Commun (Camb) (2012) 0.88