Published in Pharm Res on June 21, 2011
Plasma protein binding of sorafenib, a multi kinase inhibitor: in vitro and in cancer patients. Invest New Drugs (2011) 1.25
Sorafenib exposure decreases over time in patients with hepatocellular carcinoma. Invest New Drugs (2011) 1.05
Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary study. PLoS One (2012) 0.84
Prognostic significance of adverse events in patients with hepatocellular carcinoma treated with sorafenib. Therap Adv Gastroenterol (2016) 0.82
Sorafenib in advanced melanoma: a critical role for pharmacokinetics? Br J Cancer (2012) 0.81
Evaluation of antiangiogenic efficacy in advanced hepatocellular carcinoma: Biomarkers and functional imaging. World J Hepatol (2015) 0.81
Sorafenib dose escalation is not uniformly associated with blood pressure elevations in normotensive patients with advanced malignancies. Clin Pharmacol Ther (2014) 0.78
Overexpression of c-Jun contributes to sorafenib resistance in human hepatoma cell lines. PLoS One (2017) 0.75
Exogenous albumin inhibits sorafenib-induced cytotoxicity in human cancer cell lines. Mol Clin Oncol (2012) 0.75
Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. J Clin Oncol (2011) 6.16
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Controlling tumor growth by modulating endogenous production of reactive oxygen species. Cancer Res (2005) 3.12
Lipid raft-associated protein sorting in exosomes. Blood (2003) 2.76
Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem (2003) 2.71
The exosome pathway in K562 cells is regulated by Rab11. J Cell Sci (2002) 2.11
Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J Mol Biol (2002) 1.75
Sarcopenia predicts early dose-limiting toxicities and pharmacokinetics of sorafenib in patients with hepatocellular carcinoma. PLoS One (2012) 1.53
Efficiency and tolerance of mitotane in Cushing's disease in 76 patients from a single center. Eur J Endocrinol (2012) 1.51
Cost effectiveness of integrated medicine in patients with cancer receiving anticancer chemotherapy. J Oncol Pract (2012) 1.50
Prognostic impact of vitamin B6 metabolism in lung cancer. Cell Rep (2012) 1.45
The commonest primary sites for metastatic disease to the ovaries. J Surg Oncol (2007) 1.39
Exosome secretion: the art of reutilizing nonrecycled proteins? Traffic (2004) 1.37
Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B. Proc Natl Acad Sci U S A (2008) 1.36
Treatment for metastatic malignant melanoma: old drugs and new strategies. Crit Rev Oncol Hematol (2009) 1.32
Breast cancer in pregnancy: recommendations of an international consensus meeting. Eur J Cancer (2010) 1.31
Reticulocyte membrane remodeling: contribution of the exosome pathway. Curr Opin Hematol (2010) 1.31
Degradation of AP2 during reticulocyte maturation enhances binding of hsc70 and Alix to a common site on TFR for sorting into exosomes. Traffic (2004) 1.31
Reduced phosphatase activity of SHP-2 in LEOPARD syndrome: consequences for PI3K binding on Gab1. FEBS Lett (2006) 1.30
Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages. Blood (2009) 1.27
The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix. EMBO J (2004) 1.27
Proteomic analysis of secreted exosomes. Subcell Biochem (2007) 1.22
Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention. Proc Natl Acad Sci U S A (2014) 1.22
Posterior reversible encephalopathy syndrome induced by anti-VEGF agents. Target Oncol (2011) 1.17
Adenoma detection rate and risk of colorectal cancer and death. N Engl J Med (2014) 1.14
Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo. Mol Cancer Ther (2012) 1.13
Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors. Blood (2002) 1.12
Variability of sorafenib toxicity and exposure over time: a pharmacokinetic/pharmacodynamic analysis. Oncologist (2012) 1.10
Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes. PLoS One (2012) 1.09
An observational study of bevacizumab-induced hypertension as a clinical biomarker of antitumor activity. Oncologist (2011) 1.08
Use of platinum derivatives during pregnancy. Cancer (2008) 1.08
Endoscopic submucosal dissection: the best way to deal with subsquamous metaplasia? Endoscopy (2015) 1.06
Pneumatosis intestinalis associated with treatment of cancer patients with the vascular growth factor receptor tyrosine kinase inhibitors sorafenib and sunitinib. Invest New Drugs (2010) 1.05
Sorafenib exposure decreases over time in patients with hepatocellular carcinoma. Invest New Drugs (2011) 1.05
Drug-induced effects on erlotinib metabolism. N Engl J Med (2011) 1.03
Reticulocyte-secreted exosomes bind natural IgM antibodies: involvement of a ROS-activatable endosomal phospholipase iPLA2. Blood (2007) 1.02
Saturable absorption of sorafenib in patients with solid tumors: a population model. Invest New Drugs (2011) 1.02
Arsenic trioxide exerts antitumor activity through regulatory T cell depletion mediated by oxidative stress in a murine model of colon cancer. J Immunol (2012) 1.02
Cerebrospinal fluid concentrations of vemurafenib in patients treated for brain metastatic BRAF-V600 mutated melanoma. Melanoma Res (2015) 1.01
Reticulocyte maturation: mitoptosis and exosome release. Biocell (2002) 1.00
Gynecologic cancers in pregnancy: guidelines of a second international consensus meeting. Int J Gynecol Cancer (2014) 0.98
The Glut1 and Glut4 glucose transporters are differentially expressed during perinatal and postnatal erythropoiesis. Blood (2008) 0.98
Bevacizumab-induced cardiovascular events: a consequence of cholesterol emboli syndrome? J Natl Cancer Inst (2007) 0.96
Mannose receptor contribution to Candida albicans phagocytosis by murine E-clone J774 macrophages. J Leukoc Biol (2003) 0.96
Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression. Exp Hematol (2003) 0.95
Early experience with a novel hemostatic powder used to treat upper GI bleeding related to malignancies or after therapeutic interventions (with videos). Gastrointest Endosc (2013) 0.94
Helpfulness of the combination of acetic acid and FICE in the detection of Barrett's epithelium and Barrett's associated neoplasias. World J Gastroenterol (2012) 0.94
Toxicity of sorafenib: clinical and molecular aspects. Expert Opin Drug Saf (2010) 0.92
Exosome release by reticulocytes--an integral part of the red blood cell differentiation system. Blood Cells Mol Dis (2005) 0.92
Reversible decrease of portal venous flow in cirrhotic patients: a positive side effect of sorafenib. PLoS One (2011) 0.92
Which patients with colorectal cancer are followed up by general practitioners? A population-based study. Eur J Cancer Prev (2007) 0.91
Netrin-4 delays colorectal cancer carcinomatosis by inhibiting tumor angiogenesis. Am J Pathol (2011) 0.91
A simple HPLC-UV method for the simultaneous quantification of gefitinib and erlotinib in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2011) 0.90
The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume. Blood (2009) 0.90
Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir. J Clin Invest (2013) 0.90
Chronic rectal ulcer as result of combined mucosal toxicity of NSAID, argon plasma coagulation and radiotherapy. Dig Liver Dis (2011) 0.90
Severe toxicity related to a pharmacokinetic interaction between docetaxel and ritonavir in HIV-infected patients. Br J Clin Pharmacol (2010) 0.89
Possible pharmacokinetic interaction involving ritonavir and docetaxel in a patient with Kaposi's sarcoma. AIDS (2008) 0.89
Vitamin B6 metabolism influences the intracellular accumulation of cisplatin. Cell Cycle (2012) 0.89
A dramatic fetal outcome following transplacental transfer of dasatinib. Anticancer Drugs (2012) 0.89
Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation. J Neurosci (2013) 0.89
Prognostic value of LIPC in non-small cell lung carcinoma. Cell Cycle (2013) 0.88