PubRank

Norbert O Reich

Author PubWeight™ 58.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Laser-Activated Gene Silencing via Gold Nanoshell-siRNA Conjugates. ACS Nano 2009 1.61
2 Fabrication of Ag@SiO(2)@Y(2)O(3):Er nanostructures for bioimaging: tuning of the upconversion fluorescence with silver nanoparticles. J Am Chem Soc 2010 1.35
3 Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation. J Biol Chem 2012 1.23
4 The inherent processivity of the human de novo methyltransferase 3A (DNMT3A) is enhanced by DNMT3L. J Biol Chem 2010 1.14
5 Controlled spacing of cationic gold nanoparticles by nanocrown RNA. J Am Chem Soc 2005 1.09
6 Reagentless, electrochemical approach for the specific detection of double- and single-stranded DNA binding proteins. Anal Chem 2009 1.08
7 DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition. Biochemistry 2005 1.06
8 Simultaneous DNA binding and bending by EcoRV endonuclease observed by real-time fluorescence. Biochemistry 2003 1.06
9 The mechanism of target base attack in DNA cytosine carbon 5 methylation. Biochemistry 2004 1.06
10 Detection of sequence-specific protein-DNA interactions via surface enhanced resonance Raman scattering. J Am Chem Soc 2007 1.01
11 Statistical coevolution analysis and molecular dynamics: identification of amino acid pairs essential for catalysis. Proc Natl Acad Sci U S A 2005 1.01
12 Mapping local pH in live cells using encapsulated fluorescent SERS nanotags. Small 2010 1.00
13 The early expressed HIV-1 genes regulate DNMT1 expression. Epigenetics 2008 1.00
14 Oligomerization of DNMT3A controls the mechanism of de novo DNA methylation. J Biol Chem 2011 0.99
15 The role of high affinity non-specific DNA binding by Lrp in transcriptional regulation and DNA organization. J Mol Biol 2007 0.98
16 Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14. Nucleic Acids Res 2011 0.96
17 Identification of a second DNA binding site in human DNA methyltransferase 3A by substrate inhibition and domain deletion. Arch Biochem Biophys 2010 0.96
18 Cell-targeted self-assembled DNA nanostructures. J Am Chem Soc 2009 0.95
19 The role of Arg165 towards base flipping, base stabilization and catalysis in M.HhaI. J Mol Biol 2006 0.95
20 GATC flanking sequences regulate Dam activity: evidence for how Dam specificity may influence pap expression. J Mol Biol 2005 0.93
21 RNA modulation of the human DNA methyltransferase 3A. Nucleic Acids Res 2012 0.93
22 Chemically patterned microspheres for controlled nanoparticle assembly in the construction of SERS hot spots. J Am Chem Soc 2007 0.92
23 Competitive Lrp and Dam assembly at the pap regulatory region: implications for mechanisms of epigenetic regulation. J Mol Biol 2008 0.92
24 Selective inhibitors of bacterial DNA adenine methyltransferases. J Biomol Screen 2006 0.92
25 Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays. Nucleic Acids Res 2009 0.91
26 Facile synthesis of naphthoquinone spiroketals by diastereoselective oxidative [3 + 2] cycloaddition. Org Lett 2007 0.91
27 Specific and sensitive detection of nucleic acids and RNases using gold nanoparticle-RNA-fluorescent dye conjugates. Chem Commun (Camb) 2007 0.90
28 A heterogeneous PNA-based SERS method for DNA detection. J Am Chem Soc 2007 0.90
29 Transcription factor beacons for the quantitative detection of DNA binding activity. J Am Chem Soc 2011 0.90
30 Enzyme-directed positioning of nanoparticles on large DNA templates. Bioconjug Chem 2007 0.89
31 Long-range structural and dynamical changes induced by cofactor binding in DNA methyltransferase M.HhaI. Biochemistry 2007 0.89
32 Simultaneous DNA binding, bending, and base flipping: evidence for a novel M.EcoRI methyltransferase-DNA complex. J Biol Chem 2004 0.89
33 Conformational transitions as determinants of specificity for the DNA methyltransferase EcoRI. J Biol Chem 2006 0.88
34 Mechanism of allosteric regulation of Dnmt1's processivity. Biochemistry 2005 0.87
35 S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation. Biochemistry 2007 0.86
36 Functional analysis of BamHI DNA cytosine-N4 methyltransferase. J Mol Biol 2003 0.85
37 AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI. J Mol Biol 2007 0.85
38 Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA. Nano Lett 2014 0.84
39 Escherichia coli DNA adenine methyltransferase: intrasite processivity and substrate-induced dimerization and activation. Biochemistry 2009 0.84
40 Enzymatic manipulation of DNA-nanomaterial constructs. J Am Chem Soc 2002 0.84
41 Determinants of sequence-specific DNA methylation: target recognition and catalysis are coupled in M.HhaI. Biochemistry 2006 0.84
42 Robust SERS enhancement factor statistics using rotational correlation spectroscopy. Nano Lett 2012 0.84
43 Coupling sequence-specific recognition to DNA modification. J Biol Chem 2009 0.83
44 Modulation of Escherichia coli DNA methyltransferase activity by biologically derived GATC-flanking sequences. J Biol Chem 2008 0.83
45 Determinants of precatalytic conformational transitions in the DNA cytosine methyltransferase M.HhaI. Biochemistry 2011 0.82
46 STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition. Nucleic Acids Res 2012 0.81
47 Molecular scale architecture: engineered three- and four-way junctions. Bioconjug Chem 2007 0.81
48 Differential stabilization of reaction intermediates: specificity checkpoints for M.EcoRI revealed by transient fluorescence and fluorescence lifetime studies. Nucleic Acids Res 2008 0.80
49 A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase. J Biol Chem 2002 0.79
50 Distal structural elements coordinate a conserved base flipping network. Biochemistry 2013 0.79
51 A new strategy for detection and development of tractable telomerase inhibitors. J Med Chem 2012 0.79
52 DNA methylation modulates Salmonella enterica serovar Typhimurium virulence in Caenorhabditis elegans. FEMS Microbiol Lett 2005 0.79
53 Engineered extrahelical base destabilization enhances sequence discrimination of DNA methyltransferase M.HhaI. J Mol Biol 2006 0.79
54 Escherichia coli DNA adenine methyltransferase: the structural basis of processive catalysis and indirect read-out. J Biol Chem 2009 0.78
55 Targeted intracellular delivery of proteins with spatial and temporal control. Mol Pharm 2014 0.78
56 Bacteriophage T4Dam (DNA-(adenine-N6)-methyltransferase): evidence for two distinct stages of methylation under single turnover conditions. J Biol Chem 2003 0.78
57 Self-assembly of DNA arrays into multilayer stacks. Langmuir 2009 0.77
58 The recognition pathway for the DNA cytosine methyltransferase M.HhaI. Biochemistry 2009 0.77
59 Murine DNA cytosine C(5)-methyltransferase: in vitro studies of de novo methylation spreading. Biochem Biophys Res Commun 2003 0.77
60 DNA (cytosine-N4-)- and -(adenine-N6-)-methyltransferases have different kinetic mechanisms but the same reaction route. A comparison of M.BamHI and T4 Dam. J Biol Chem 2003 0.77
61 Distinct facilitated diffusion mechanisms by E. coli Type II restriction endonucleases. Biochemistry 2014 0.76
62 Proximal recognition sites facilitate intrasite hopping by DNA adenine methyltransferase: mechanistic exploration of epigenetic gene regulation. J Biol Chem 2012 0.76
63 Molecular drivers of base flipping during sequence-specific DNA methylation. Chembiochem 2012 0.76
64 Enzyme-promoted base flipping controls DNA methylation fidelity. Biochemistry 2013 0.76
65 Gold nanoparticle decoration of DNA on silicon. Langmuir 2005 0.76