Published in PLoS One on June 16, 2011
Retracted Growth inhibition and apoptosis induced by 6-fluoro-3-formylchromone in hepatocellular carcinoma. BMC Gastroenterol (2014) 1.39
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis. Mol Cancer (2015) 1.04
CCL21/CCR7 prevents apoptosis via the ERK pathway in human non-small cell lung cancer cells. PLoS One (2012) 0.91
MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA. PLoS One (2013) 0.91
CCR7 expression and intratumoral FOXP3+ regulatory T cells are correlated with overall survival and lymph node metastasis in gastric cancer. PLoS One (2013) 0.88
CCL21/CCR7 enhances the proliferation, migration, and invasion of human bladder cancer T24 cells. PLoS One (2015) 0.86
Type 10 soluble adenylyl cyclase is overexpressed in prostate carcinoma and controls proliferation of prostate cancer cells. J Biol Chem (2012) 0.86
COPD promotes migration of A549 lung cancer cells: the role of chemokine CCL21. Int J Chron Obstruct Pulmon Dis (2016) 0.78
The role of chemoattractant receptors in shaping the tumor microenvironment. Biomed Res Int (2014) 0.77
Fine mapping reveals that promotion susceptibility locus 1 (Psl1) is a compound locus with multiple genes that modify susceptibility to skin tumor development. G3 (Bethesda) (2014) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell (1999) 32.32
Involvement of chemokine receptors in breast cancer metastasis. Nature (2001) 26.07
Mammalian MAP kinase signalling cascades. Nature (2001) 18.89
Signal transduction by the JNK group of MAP kinases. Cell (2000) 18.24
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science (2002) 14.50
Chemokines: a new classification system and their role in immunity. Immunity (2000) 13.03
Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (1997) 11.48
Chemokines and leukocyte traffic. Nature (1998) 9.79
Cyclin A is required at two points in the human cell cycle. EMBO J (1992) 7.96
Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J Exp Med (1998) 6.12
Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell (1991) 5.98
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature (1997) 5.43
Mitosis in transition. Cell (1994) 5.03
Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science (1993) 4.81
Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays (1995) 4.70
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol (1997) 4.70
Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell (1994) 4.07
The burden of community-acquired pneumonia in seniors: results of a population-based study. Clin Infect Dis (2004) 2.96
Regulation and function of the JNK subgroup of MAP kinases. Biochim Biophys Acta (1997) 2.72
Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties. J Immunol (1998) 2.70
Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma. J Natl Cancer Inst (2001) 2.64
Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts. Proc Natl Acad Sci U S A (1999) 2.29
Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression. J Virol (2005) 2.21
Synergistic action of Drosophila cyclins A and B during the G2-M transition. EMBO J (1993) 2.06
Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. J Biol Chem (1998) 2.01
Chemokine C receptor 7 expression and protection of circulating CD8+ T lymphocytes from apoptosis. Clin Cancer Res (2005) 1.73
The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed. J Immunol (2005) 1.57
CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells. Clin Cancer Res (2004) 1.50
Interleukin-6 activates PI3K/Akt pathway and regulates cyclin A1 to promote prostate cancer cell survival. Int J Cancer (2008) 1.48
Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells. Blood (2004) 1.47
Raf-1/MEK/MAPK pathway is necessary for the G2/M transition induced by nocodazole. J Biol Chem (2000) 1.39
Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma. Clin Cancer Res (2003) 1.35
Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis. Int J Cancer (2003) 1.35
Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res (2004) 1.32
Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases. Immunology (2002) 1.25
CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway. J Neurochem (2009) 1.25
Association of CXCR4 and CCR7 chemokine receptor expression and lymph node metastasis in human cervical cancer. Ann Oncol (2006) 1.18
CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes. Cancer Res (2000) 1.15
Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells. Cancer Res (2005) 1.15
CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway. Blood (2009) 1.14
Chemokine receptor 7 activates phosphoinositide-3 kinase-mediated invasive and prosurvival pathways in head and neck cancer cells independent of EGFR. Oncogene (2005) 1.13
The murine CC chemokine, 6C-kine, inhibits tumor growth and angiogenesis in a human lung cancer SCID mouse model. Cancer Immunol Immunother (2001) 1.09
Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors. J Immunol (1999) 1.08
Hypoxia induced CCR7 expression via HIF-1alpha and HIF-2alpha correlates with migration and invasion in lung cancer cells. Cancer Biol Ther (2009) 1.06
IFN{alpha} enhances human B-cell chemotaxis by modulating ligand-induced chemokine receptor signaling and internalization. Int Immunol (2005) 0.98
Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression. Phytother Res (2010) 0.97
Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells. Cell Biol Toxicol (2008) 0.96
CCR7-mediated c-Jun N-terminal kinase activation regulates cell migration in mature dendritic cells. Int Immunol (2005) 0.95
CCR7-dependent stimulation of survival in dendritic cells involves inhibition of GSK3beta. J Immunol (2009) 0.93
Effects of chemokines on proliferation and apoptosis of human mesangial cells. BMC Nephrol (2004) 0.91
Binding of the chemokine SLC/CCL21 to its receptor CCR7 increases adhesive properties of human mesangial cells. Kidney Int (2004) 0.91
Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck. Br J Oral Maxillofac Surg (2009) 0.89
Prognostic value of CCR7 expression in gastric cancer. Hepatogastroenterology (2007) 0.88
CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes. J Biol Chem (2010) 0.88
The antiproliferative activity of melatonin in B65 rat dopaminergic neuroblastoma cells is related to the downregulation of cell cycle-related genes. J Pineal Res (2008) 0.83
A critical role of CCR7 in invasiveness and metastasis of SW620 colon cancer cell in vitro and in vivo. Cancer Biol Ther (2008) 0.82
Melatonin delays cell proliferation by inducing G1 and G2 /M phase arrest in a human osteoblastic cell line hFOB 1.19. J Pineal Res (2010) 0.81
Multicolor super-resolution imaging with photo-switchable fluorescent probes. Science (2007) 9.00
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proc Natl Acad Sci U S A (2007) 6.04
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol (2013) 5.36
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev (2012) 4.19
Superresolution imaging of chemical synapses in the brain. Neuron (2010) 3.51
Conformational biosensors reveal GPCR signalling from endosomes. Nature (2013) 3.29
Identification of competence pheromone responsive genes in Streptococcus pneumoniae by use of DNA microarrays. Mol Microbiol (2004) 3.29
Effectiveness of strengthened stimulation during acupuncture for the treatment of Bell palsy: a randomized controlled trial. CMAJ (2013) 3.15
Faster STORM using compressed sensing. Nat Methods (2012) 2.61
Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A (2012) 2.46
The Kluyveromyces lactis gamma-toxin targets tRNA anticodons. RNA (2005) 2.39
Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma. Nat Commun (2013) 2.27
Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis. Mol Cell (2006) 2.22
Eukaryotic wobble uridine modifications promote a functionally redundant decoding system. Mol Cell Biol (2008) 2.21
IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma. J Immunol (2008) 2.17
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. Cell Stem Cell (2013) 2.17
Soft fibrin gels promote selection and growth of tumorigenic cells. Nat Mater (2012) 2.15
Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J (2009) 2.05
Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer. Cancer Sci (2010) 2.04
Cyclophilin A/Cluster of Differentiation 147 Interactions Participate in Early Brain Injury After Subarachnoid Hemorrhage in Rats. Crit Care Med (2015) 2.01
Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium. PLoS Genet (2010) 1.98
Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer. J Natl Cancer Inst (2002) 1.95
Season, sex, age, and education as modifiers of the effects of outdoor air pollution on daily mortality in Shanghai, China: The Public Health and Air Pollution in Asia (PAPA) Study. Environ Health Perspect (2008) 1.92
Toward reliable characterization of functional homogeneity in the human brain: preprocessing, scan duration, imaging resolution and computational space. Neuroimage (2012) 1.92
A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA (2007) 1.88
Differentiating the effects of fine and coarse particles on daily mortality in Shanghai, China. Environ Int (2007) 1.86
Local accumulation of FOXP3+ regulatory T cells: evidence for an immune evasion mechanism in patients with large condylomata acuminata. J Immunol (2008) 1.83
Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing. Nat Methods (2012) 1.80
Logarithmic sensing in Escherichia coli bacterial chemotaxis. Biophys J (2009) 1.78
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J (2007) 1.74
Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells. BMC Cancer (2010) 1.72
Influenza-associated mortality in temperate and subtropical Chinese cities, 2003-2008. Bull World Health Organ (2012) 1.69
Human pregnancy up-regulates Tim-3 in innate immune cells for systemic immunity. J Immunol (2009) 1.68
Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS One (2009) 1.65
GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA. Genes Dev (2009) 1.62
Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC). J Leukoc Biol (2010) 1.62
Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry. Cancer Res (2011) 1.59
Reactive astrocytes secrete lcn2 to promote neuron death. Proc Natl Acad Sci U S A (2013) 1.59
CD24 polymorphisms affect risk and progression of chronic hepatitis B virus infection. Hepatology (2009) 1.56
Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium. Hum Mol Genet (2011) 1.55
Coupling between clathrin-dependent endocytic budding and F-BAR-dependent tubulation in a cell-free system. Nat Cell Biol (2010) 1.55
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res (2013) 1.54
Lats2 is a negative regulator of myocyte size in the heart. Circ Res (2008) 1.53
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem (2006) 1.52
Super-resolution microscopy by nanoscale localization of photo-switchable fluorescent probes. Curr Opin Chem Biol (2008) 1.46
Mechanisms of plant salt response: insights from proteomics. J Proteome Res (2011) 1.45
The Hippo effector Yorkie controls normal tissue growth by antagonizing scalloped-mediated default repression. Dev Cell (2013) 1.43
Transcriptional activity regulates alternative cleavage and polyadenylation. Mol Syst Biol (2011) 1.41
ComX is a unique link between multiple quorum sensing outputs and competence in Streptococcus pneumoniae. Mol Microbiol (2003) 1.41
Mast cells mobilize myeloid-derived suppressor cells and Treg cells in tumor microenvironment via IL-17 pathway in murine hepatocarcinoma model. PLoS One (2010) 1.39
Diurnal temperature range and daily mortality in Shanghai, China. Environ Res (2007) 1.35
Selective depletion of CD4+CD25+Foxp3+ regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels. Cancer Res (2010) 1.32
Extended arrays of vertically aligned sub-10 nm diameter [100] Si nanowires by metal-assisted chemical etching. Nano Lett (2008) 1.31
Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification. PLoS Genet (2011) 1.30
RNA-binding protein quaking, a critical regulator of colon epithelial differentiation and a suppressor of colon cancer. Gastroenterology (2009) 1.29
TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Nat Neurosci (2013) 1.28
Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage. Cancer Res (2010) 1.28
Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of cysteines 93 and 310. Nucleic Acids Res (2007) 1.26
Population exposure to PM2.5 in the urban area of Beijing. PLoS One (2013) 1.26
Counting molecules in single organelles with superresolution microscopy allows tracking of the endosome maturation trajectory. Proc Natl Acad Sci U S A (2013) 1.26
Construction of microfluidic chips using polydimethylsiloxane for adhesive bonding. Lab Chip (2005) 1.25
Phase II study of the anti-cytotoxic T-lymphocyte-associated antigen 4 monoclonal antibody, tremelimumab, in patients with refractory metastatic colorectal cancer. J Clin Oncol (2010) 1.24
Chemical composition and antifungal activity of essential oil from Cicuta virosa L. var. latisecta Celak. Int J Food Microbiol (2011) 1.23
Crystal structure of cytotoxin protein suilysin from Streptococcus suis. Protein Cell (2010) 1.23
Characteristics of stem cells derived from the degenerated human intervertebral disc cartilage endplate. PLoS One (2011) 1.22
Funneled landscape leads to robustness of cell networks: yeast cell cycle. PLoS Comput Biol (2006) 1.21
Hemicellulose biosynthesis. Planta (2013) 1.21
Generation of complex, static solution gradients in microfluidic channels. J Am Chem Soc (2006) 1.21
Identification of ComW as a new component in the regulation of genetic transformation in Streptococcus pneumoniae. Mol Microbiol (2004) 1.20
Retracted Funneled landscape leads to robustness of cellular networks: MAPK signal transduction. Biophys J (2006) 1.20
Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study. PLoS One (2011) 1.19
Regulation of TNF mediated antiapoptotic signaling in human neutrophils: role of delta-PKC and ERK1/2. J Leukoc Biol (2006) 1.19
DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression. BMC Mol Biol (2010) 1.19
Kluyveromyces lactis gamma-toxin, a ribonuclease that recognizes the anticodon stem loop of tRNA. Nucleic Acids Res (2007) 1.18
Delivery of chemotherapeutic drugs in tumour cell-derived microparticles. Nat Commun (2012) 1.18
Ozone and daily mortality in Shanghai, China. Environ Health Perspect (2006) 1.18
Low-grade cribriform cystadenocarcinoma of salivary glands: report of two cases and review of the literature. Diagn Pathol (2013) 1.17
Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxide-mediated cytotoxicity in murine neuroblastoma cells. Free Radic Biol Med (2007) 1.15
Interleukin 7/interleukin 7 receptor induce c-Fos/c-Jun-dependent vascular endothelial growth factor-D up-regulation: a mechanism of lymphangiogenesis in lung cancer. Eur J Cancer (2009) 1.14
The landscape of accessible chromatin in mammalian preimplantation embryos. Nature (2016) 1.13
Phase 1 dose-escalation trial of tremelimumab plus sunitinib in patients with metastatic renal cell carcinoma. Cancer (2010) 1.12
Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A. Proc Natl Acad Sci U S A (2013) 1.12
In vitro and in vivo antioxidant effects of the ethanolic extract of Swertia chirayita. J Ethnopharmacol (2011) 1.12
MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met. PLoS One (2013) 1.12
Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population. Mol Carcinog (2013) 1.12
Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression. J Biol Chem (2005) 1.11
Anti-Diabetic Effect of Pectinase-Processed Ginseng Radix (GINST) in High Fat Diet-Fed ICR Mice. J Ginseng Res (2011) 1.11
Cytokines in CSF correlate with HIV-associated neurocognitive disorders in the post-HAART era in China. J Neurovirol (2013) 1.10
Effect of bin time on the photon counting histogram for one-photon excitation. Chemphyschem (2005) 1.08
Photon counting histogram for one-photon excitation. Chemphyschem (2003) 1.08
Overexpression of TRIM24 correlates with tumor progression in non-small cell lung cancer. PLoS One (2012) 1.07