Published in EMBO J on January 01, 1993
Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. J Cell Biol (2001) 3.86
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis. Dev Cell (2010) 3.72
Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J (1995) 3.45
Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev Cell (2008) 2.82
Human cyclin A is required for mitosis until mid prophase. J Cell Biol (1999) 2.31
Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. Genes Dev (1998) 2.09
Functional antagonism between E2F family members. Genes Dev (2001) 2.03
Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes Dev (1998) 1.82
Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways. Dev Biol (2007) 1.82
The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis. Curr Biol (2001) 1.66
A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle. EMBO J (1993) 1.59
Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins. EMBO J (1994) 1.50
Transcriptional regulation of string (cdc25): a link between developmental programming and the cell cycle. Development (1994) 1.45
Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster. J Cell Biol (2007) 1.44
S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells. Mol Cell Biol (2001) 1.44
Drosophila separase is required for sister chromatid separation and binds to PIM and THR. Genes Dev (2001) 1.40
S-phase function of Drosophila cyclin A and its downregulation in G1 phase. Curr Biol (1997) 1.36
Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J (1996) 1.33
Isolation of Drosophila cyclin D, a protein expressed in the morphogenetic furrow before entry into S phase. Proc Natl Acad Sci U S A (1996) 1.30
Myb controls G(2)/M progression by inducing cyclin B expression in the Drosophila eye imaginal disc. EMBO J (2002) 1.29
Degradation of Drosophila PIM regulates sister chromatid separation during mitosis. Genes Dev (2000) 1.28
Ionizing radiation induces apoptosis and elevates cyclin A1-Cdk2 activity before but not after the midblastula transition in Xenopus. Mol Biol Cell (1997) 1.23
Chromosome association of minichromosome maintenance proteins in Drosophila mitotic cycles. J Cell Biol (1997) 1.22
Cell cycle regulation in Aspergillus by two protein kinases. Biochem J (1996) 1.22
Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A (2000) 1.20
Rux is a cyclin-dependent kinase inhibitor (CKI) specific for mitotic cyclin-Cdk complexes. Curr Biol (1999) 1.19
The degradation of two mitotic cyclins contributes to the timing of cytokinesis. Curr Biol (2003) 1.15
Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development. Genetics (1998) 1.13
Developmentally regulated histone modifications in Drosophila follicle cells: initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation. Chromosoma (2007) 1.13
The Drosophila melanogaster condensin subunit Cap-G interacts with the centromere-specific histone H3 variant CID. Chromosoma (2004) 1.10
A complex degradation signal in Cyclin A required for G1 arrest, and a C-terminal region for mitosis. EMBO J (2001) 1.10
Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila. Dev Biol (2007) 1.00
Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring. J Biol Chem (2009) 1.00
Sex-lethal facilitates the transition from germline stem cell to committed daughter cell in the Drosophila ovary. Genetics (2009) 0.99
In vitro fusion of endocytic vesicles is inhibited by cyclin A-cdc2 kinase. Mol Biol Cell (1993) 0.96
Cdks and the Drosophila cell cycle. Curr Opin Genet Dev (1997) 0.96
Drosophila Xpd regulates Cdk7 localization, mitotic kinase activity, spindle dynamics, and chromosome segregation. PLoS Genet (2010) 0.96
Influence of cyclin type and dose on mitotic entry and progression in the early Drosophila embryo. J Cell Biol (2009) 0.96
smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye. Development (2006) 0.93
Spindle checkpoint-independent inhibition of mitotic chromosome segregation by Drosophila Mps1. Mol Biol Cell (2012) 0.93
A clonal genetic screen for mutants causing defects in larval tracheal morphogenesis in Drosophila. Genetics (2007) 0.93
Mutations in ccf, a novel Drosophila gene encoding a chromosomal factor, affect progression through mitosis and interact with Pc-G mutations. EMBO J (1998) 0.92
Defective decapentaplegic signaling results in heart overgrowth and reduced cardiac output in Drosophila. Genetics (2007) 0.92
Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition. Curr Biol (2015) 0.92
Drosophila nemo promotes eye specification directed by the retinal determination gene network. Genetics (2008) 0.92
CCL21/CCR7 promotes G2/M phase progression via the ERK pathway in human non-small cell lung cancer cells. PLoS One (2011) 0.91
Roughex mediates G(1) arrest through a physical association with cyclin A. Mol Cell Biol (2000) 0.90
Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathway. JAKSTAT (2013) 0.88
Coordinating cell polarity and cell cycle progression: what can we learn from flies and worms? Open Biol (2013) 0.87
The pineapple eye gene is required for survival of Drosophila imaginal disc cells. Genetics (2003) 0.86
Cell cycle arrest by a gradient of Dpp signaling during Drosophila eye development. BMC Dev Biol (2010) 0.85
Characterization of Drosophila mini-me, a gene required for cell proliferation and survival. Genetics (2006) 0.84
Mitosis in neurons: Roughex and APC/C maintain cell cycle exit to prevent cytokinetic and axonal defects in Drosophila photoreceptor neurons. PLoS Genet (2012) 0.83
Cell cycle events during the development of the silk glands in the mulberry silkworm Bombyx mori. Dev Genes Evol (2003) 0.83
Temporal control of epigenetic centromere specification. Chromosome Res (2012) 0.83
The biochemistry of mitosis. Cold Spring Harb Perspect Biol (2015) 0.82
Effects of seawater acidification on cell cycle control mechanisms in Strongylocentrotus purpuratus embryos. PLoS One (2012) 0.82
Functional characterization of the dRYBP gene in Drosophila. Genetics (2008) 0.82
Notch activity opposes Ras-induced differentiation during the Second Mitotic Wave of the developing Drosophila eye. BMC Dev Biol (2006) 0.81
Cellular sensory mechanisms for detecting specific fold-changes in extracellular cues. Biophys J (2014) 0.80
Eye development. Methods (2014) 0.78
Drosophila embryonic cell-cycle mutants. G3 (Bethesda) (2013) 0.77
Spire, an actin nucleation factor, regulates cell division during Drosophila heart development. PLoS One (2012) 0.76
An essential step of kinetochore formation controlled by the SNARE protein Snap29. EMBO J (2016) 0.76
Inhibition of Daughterless by Extramacrochaetae mediates Notch-induced cell proliferation. Development (2015) 0.75
Investigating the Interplay between Sister Chromatid Cohesion and Homolog Pairing in Drosophila Nuclei. PLoS Genet (2016) 0.75
Distinct and Overlapping Requirements for Cyclins A, B and B3 in Drosophila Female Meiosis. G3 (Bethesda) (2016) 0.75
Identification of novel SAR properties of the Jak2 small molecule inhibitor G6: significance of the para-hydroxyl orientation. Bioorg Med Chem Lett (2011) 0.75
Checkpoints: controls that ensure the order of cell cycle events. Science (1989) 21.01
Cyclin is degraded by the ubiquitin pathway. Nature (1991) 17.93
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature (1989) 11.90
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell (1987) 8.76
Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2. Cell (1989) 8.19
A novel cyclin encoded by a bcl1-linked candidate oncogene. Nature (1991) 7.98
Cyclin A is required at two points in the human cell cycle. EMBO J (1992) 7.96
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature (1990) 7.34
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J Cell Biol (1991) 7.18
Cyclin activation of p34cdc2. Cell (1990) 6.87
Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell (1991) 6.65
cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2. Cell (1991) 6.32
mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell (1991) 6.25
Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell (1991) 5.98
The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell (1991) 5.81
Human D-type cyclin. Cell (1991) 5.47
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell (1992) 5.05
A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell (1991) 4.90
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell (1991) 4.88
Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. EMBO J (1991) 4.59
Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis. Cell (1989) 4.56
Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein. Nature (1991) 4.54
The cdc25 protein contains an intrinsic phosphatase activity. Cell (1991) 4.39
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature (1991) 4.36
Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell (1991) 4.33
The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J (1990) 4.25
Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites. EMBO J (1991) 4.24
The roles of Drosophila cyclins A and B in mitotic control. Cell (1990) 4.22
Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol Biol Cell (1992) 4.17
Expression and function of Drosophila cyclin A during embryonic cell cycle progression. Cell (1989) 4.10
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J (1991) 4.04
Regulation of the cdc25 protein during the cell cycle in Xenopus extracts. Cell (1992) 3.95
Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase. Nature (1991) 3.86
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex. Cell (1992) 3.64
p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J (1991) 3.55
The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell (1990) 3.40
Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A. Proc Natl Acad Sci U S A (1992) 3.38
Involvement of cdc13+ in mitotic control in Schizosaccharomyces pombe: possible interaction of the gene product with microtubules. EMBO J (1988) 3.27
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates. EMBO J (1991) 3.23
cdc2 phosphorylation is required for its interaction with cyclin. EMBO J (1991) 3.22
Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner. EMBO J (1991) 3.16
Cell shape changes during gastrulation in Drosophila. Development (1990) 3.12
Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis. J Cell Sci (1988) 2.96
Both cyclin A delta 60 and B delta 97 are stable and arrest cells in M-phase, but only cyclin B delta 97 turns on cyclin destruction. EMBO J (1991) 2.85
Cyclin A is required in S phase in normal epithelial cells. Biochem Biophys Res Commun (1992) 2.55
An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins. Cell (1991) 2.19
Regulation of the microtubule nucleating activity of centrosomes in Xenopus egg extracts: role of cyclin A-associated protein kinase. J Cell Biol (1992) 1.82
Dephosphorylation of cdc2 on threonine 161 is required for cdc2 kinase inactivation and normal anaphase. EMBO J (1992) 1.77
Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis. Nature (1989) 1.63
Activation of p34cdc2 kinase by cyclin A. J Cell Biol (1991) 1.62
Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts. EMBO J (1992) 1.41
The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila. Cell (1992) 1.38
A novel cyclin gene from Drosophila complements CLN function in yeast. Genes Dev (1991) 1.21
Cyclin A-cdc2 kinase does not trigger but delays cyclin degradation in interphase extracts of amphibian eggs. J Cell Sci (1992) 1.19
Inhibition of membrane fusion in vitro via cyclin B but not cyclin A. J Biol Chem (1992) 1.12
Exploring the role of Drosophila cyclin A in the regulation of S phase. Cold Spring Harb Symp Quant Biol (1991) 1.05
Regulation of protein kinases associated with cyclin A and cyclin B and their effect on microtubule dynamics and nucleation in Xenopus egg extracts. Cold Spring Harb Symp Quant Biol (1991) 0.96
A genetic analysis of the rose-gespleten region (68C8-69B5) of Drosophila melanogaster. Genetics (1988) 0.95
Cyclin B mRNA depletion only transiently inhibits the Xenopus embryonic cell cycle. Development (1991) 0.90
Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell (1989) 7.21
Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell (1994) 4.07
Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Cell (1997) 3.83
Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J (1995) 3.45
Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell (1996) 2.69
Developmental control of cell cycle regulators: a fly's perspective. Science (1996) 2.68
Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes Dev (1995) 2.36
The Drosophila cyclin D-Cdk4 complex promotes cellular growth. EMBO J (2000) 2.19
Directing cell division during development. Science (1989) 2.08
Cell cycle progression, growth and patterning in imaginal discs despite inhibition of cell division after inactivation of Drosophila Cdc2 kinase. Development (1997) 1.83
The nuclear lamin protein family in higher vertebrates. Identification of quantitatively minor lamin proteins by monoclonal antibodies. J Biol Chem (1986) 1.83
Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes Dev (1998) 1.82
Differential expression of nuclear lamin proteins during chicken development. J Cell Biol (1987) 1.70
Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression. EMBO J (2000) 1.63
Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition. Cell (1996) 1.55
Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila. Curr Biol (1998) 1.47
The fates of chicken nuclear lamin proteins during mitosis: evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum. J Cell Biol (1988) 1.47
Genetic analysis of the Drosophila cdc2 homolog. Development (1993) 1.42
The Drosophila cdc25 homolog twine is required for meiosis. Development (1992) 1.40
Drosophila separase is required for sister chromatid separation and binds to PIM and THR. Genes Dev (2001) 1.40
Degradation of Drosophila PIM regulates sister chromatid separation during mitosis. Genes Dev (2000) 1.28
A second higher vertebrate B-type lamin. cDNA sequence determination and in vitro processing of chicken lamin B2. J Mol Biol (1989) 1.28
Biogenesis of the nuclear lamina: in vivo synthesis and processing of nuclear protein precursors. Proc Natl Acad Sci U S A (1986) 1.26
Nuclear substructure antigens. Monoclonal antibodies against components of nuclear matrix preparations. Exp Cell Res (1986) 1.22
Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins. J Mol Biol (1989) 1.19
roughex down-regulates G2 cyclins in G1. Genes Dev (1997) 1.19
Reduction of Cre recombinase toxicity in proliferating Drosophila cells by estrogen-dependent activity regulation. Dev Genes Evol (2001) 1.16
A monoclonal antibody specific for snRNPs U1 and U2. FEBS Lett (1986) 1.14
Caenorhabditis elegans cyclin A- and B-type genes: a cyclin A multigene family, an ancestral cyclin B3 and differential germline expression. J Cell Sci (1995) 1.14
A screen for modifiers of cyclin E function in Drosophila melanogaster identifies Cdk2 mutations, revealing the insignificance of putative phosphorylation sites in Cdk2. Genetics (2000) 1.11
A complex degradation signal in Cyclin A required for G1 arrest, and a C-terminal region for mitosis. EMBO J (2001) 1.10
Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase. Mol Biol Cell (1996) 1.07
Cell fate specification by even-skipped expression in the Drosophila nervous system is coupled to cell cycle progression. Development (1995) 1.07
The role of cyclin E in the regulation of entry into S phase. Prog Cell Cycle Res (1995) 1.06
Dmcdc2 kinase is required for both meiotic divisions during Drosophila spermatogenesis and is activated by the Twine/cdc25 phosphatase. Mech Dev (1995) 0.98
The three rows gene of Drosophila melanogaster encodes a novel protein that is required for chromosome disjunction during mitosis. Mol Biol Cell (1993) 0.97
The beauty of small flies. Nat Cell Biol (1999) 0.86