Published in Osteoarthritis Cartilage on June 16, 2011
Study to Prevent Cartilage Damage Following Acute Knee Injury. | NCT00332254
Value of biomarkers in osteoarthritis: current status and perspectives. Ann Rheum Dis (2013) 1.40
Cartilage damage in osteoarthritis and rheumatoid arthritis-two unequal siblings. Nat Rev Rheumatol (2015) 1.03
Cartilage and bone changes during development of post-traumatic osteoarthritis in selected LGXSM recombinant inbred mice. Osteoarthritis Cartilage (2012) 0.96
A systems view of risk factors for knee osteoarthritis reveals insights into the pathogenesis of the disease. Ann Biomed Eng (2014) 0.89
Metal-on-metal hip resurfacing arthroplasty: an analysis of safety and revision rates. Ont Health Technol Assess Ser (2012) 0.83
Magnetic Capture of a Molecular Biomarker from Synovial Fluid in a Rat Model of Knee Osteoarthritis. Ann Biomed Eng (2015) 0.80
Republished: Value of biomarkers in osteoarthritis: current status and perspectives. Postgrad Med J (2014) 0.80
Osteoarthritis: a perspective from the arthritis foundation: we need a base hit. HSS J (2012) 0.75
Computed tomography of subchondral bone and osteophytes in hip osteoarthritis: the shape of things to come? Front Endocrinol (Lausanne) (2011) 0.75
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product. Proc Natl Acad Sci U S A (1992) 4.27
Genetic influences on osteoarthritis in women: a twin study. BMJ (1996) 3.70
Classification of osteoarthritis biomarkers: a proposed approach. Osteoarthritis Cartilage (2006) 3.10
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes. Genes Dev (1991) 2.40
Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: the Johnston County Osteoarthritis Project. Arthritis Rheum (1999) 2.36
Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2. J Cell Biol (1999) 2.17
Eukaryotic translation initiation factor 5 (eIF5) acts as a classical GTPase-activator protein. Curr Biol (2001) 2.09
Basic methods in histopathology of joint tissues. Osteoarthritis Cartilage (2010) 2.08
Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest (1988) 1.89
European Y-chromosomal lineages in Polynesians: a contrast to the population structure revealed by mtDNA. Am J Hum Genet (1998) 1.87
Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9. J Bone Miner Res (1999) 1.82
Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis. Arthritis Rheum (1998) 1.79
Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative splicing of mRNA. J Biol Chem (1990) 1.75
Mutations in fibroblast growth-factor receptor 3 in sporadic cases of achondroplasia occur exclusively on the paternally derived chromosome. Am J Hum Genet (1998) 1.72
Mutations in the region encoding the von Willebrand factor A domain of matrilin-3 are associated with multiple epiphyseal dysplasia. Nat Genet (2001) 1.64
Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis. J Bone Joint Surg Br (1997) 1.60
Effects of platelet-derived growth factor and transforming growth factor-beta 1 on the synthesis of a large versican-like chondroitin sulfate proteoglycan by arterial smooth muscle cells. J Biol Chem (1991) 1.55
Structure and sequence of the chicken type II procollagen gene. Characterization of the region encoding the carboxyl-terminal telopeptide and propeptide. J Biol Chem (1984) 1.54
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Ann Rheum Dis (2010) 1.53
Serum levels of cartilage oligomeric matrix protein (COMP) correlate with radiographic progression of knee osteoarthritis. Osteoarthritis Cartilage (2002) 1.45
Value of biomarkers in osteoarthritis: current status and perspectives. Ann Rheum Dis (2013) 1.40
Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis. Arthritis Rheum (2006) 1.38
Reexpression of type IIA procollagen by adult articular chondrocytes in osteoarthritic cartilage. Arthritis Rheum (1999) 1.32
A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis. Osteoarthritis Cartilage (2002) 1.32
Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture. Spine (Phila Pa 1976) (2001) 1.29
Transcriptional suppression by interleukin-1 and interferon-gamma of type II collagen gene expression in human chondrocytes. J Cell Biochem (1994) 1.28
Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage. Am J Hum Genet (1999) 1.27
Identification of genomic DNA coding for chicken type II procollagen. J Biol Chem (1983) 1.25
Subregional femorotibial cartilage morphology in women--comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis. Osteoarthritis Cartilage (2009) 1.24
Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review. Ann Rheum Dis (2007) 1.22
Assessment of the utility of biomarkers of osteoarthritis in the guinea pig. Osteoarthritis Cartilage (2006) 1.21
Identification of an urinary metabolite profile associated with osteoarthritis. Osteoarthritis Cartilage (2005) 1.21
Type IIA procollagen amino propeptide is localized in human embryonic tissues. J Histochem Cytochem (1997) 1.20
Immunohistochemical study of collagen types I and II and procollagen IIA in human cartilage repair tissue following autologous chondrocyte implantation. Knee (2009) 1.19
Summary of the OA biomarkers workshop 2009--biochemical biomarkers: biology, validation, and clinical studies. Osteoarthritis Cartilage (2010) 1.18
Platelet-derived growth factor and transforming growth factor-beta 1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cells. Arterioscler Thromb (1993) 1.18
Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures. J Orthop Res (2001) 1.18
Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee. Osteoarthritis Cartilage (2011) 1.18
Collagen gene expression during development of avian synovial joints: transient expression of types II and XI collagen genes in the joint capsule. Dev Dyn (1995) 1.17
In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure. J Orthop Res (1996) 1.17
Exon/intron organization of the chicken type II procollagen gene: intron size distribution suggests a minimal intron size. Proc Natl Acad Sci U S A (1986) 1.17
Differential expression of small chondroitin/dermatan sulfate proteoglycans, PG-I/biglycan and PG-II/decorin, by vascular smooth muscle and endothelial cells in culture. J Biol Chem (1991) 1.17
Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA. Osteoarthritis Cartilage (2012) 1.17
Immune interferon suppresses levels of procollagen mRNA and type II collagen synthesis in cultured human articular and costal chondrocytes. J Biol Chem (1986) 1.16
Histopathology atlas of animal model systems - overview of guiding principles. Osteoarthritis Cartilage (2010) 1.14
The human type II procollagen gene: identification of an additional protein-coding domain and location of potential regulatory sequences in the promoter and first intron. Genomics (1990) 1.13
E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins. Mol Cell Biol (1993) 1.13
A 5-yr longitudinal study of type IIA collagen synthesis and total type II collagen degradation in patients with knee osteoarthritis--association with disease progression. Rheumatology (Oxford) (2007) 1.13
Identification of the proteoglycan versican in aorta and smooth muscle cells by DNA sequence analysis, in situ hybridization and immunohistochemistry. Matrix Biol (1994) 1.11
Mouse CD-RAP/MIA gene: structure, chromosomal localization, and expression in cartilage and chondrosarcoma. Dev Dyn (1997) 1.11
Stratification analysis of an osteoarthritis genome screen-suggestive linkage to chromosomes 4, 6, and 16. Am J Hum Genet (1999) 1.11
Cloning of a retinoic acid-sensitive mRNA expressed in cartilage and during chondrogenesis. J Biol Chem (1996) 1.10
Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees. Osteoarthritis Cartilage (2008) 1.10
The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants. Osteoarthritis Cartilage (2005) 1.09
Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis. Osteoarthritis Cartilage (2001) 1.08
Evaluation of locus heterogeneity and EXT1 mutations in 34 families with hereditary multiple exostoses. Hum Mutat (1998) 1.07
Serum levels of type IIA procollagen amino terminal propeptide (PIIANP) are decreased in patients with knee osteoarthritis and rheumatoid arthritis. Osteoarthritis Cartilage (2004) 1.06
Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis. J Orthop Res (2000) 1.04
Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology. Osteoarthritis Cartilage (2002) 1.03
Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes. Osteoarthritis Cartilage (2008) 1.02
Optimization of the fixed-flexion knee radiograph. Osteoarthritis Cartilage (2007) 1.01
Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. Am J Pathol (2000) 1.00
An independent analysis of the National Cancer Institute study on non-nutritive sweeteners and bladder cancer. Am J Public Health (1982) 0.99
Discoordinate gene expression of aggrecan and type II collagen in experimental osteoarthritis. Arthritis Rheum (1995) 0.99
Expression of decorin by sprouting bovine aortic endothelial cells exhibiting angiogenesis in vitro. Exp Cell Res (1992) 0.98
Clinical, radiographic, molecular and MRI-based predictors of cartilage loss in knee osteoarthritis. Ann Rheum Dis (2011) 0.97
Brachydactyly type B: linkage to chromosome 9q22 and evidence for genetic heterogeneity. Am J Hum Genet (1999) 0.97
Cartilage and bone changes during development of post-traumatic osteoarthritis in selected LGXSM recombinant inbred mice. Osteoarthritis Cartilage (2012) 0.96
Cell biology of osteoarthritis: the chondrocyte's response to injury. Curr Rheumatol Rep (2001) 0.95
The single copy gene coding for human alpha 1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13. Hum Genet (1986) 0.94
Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis. Rheumatology (Oxford) (2000) 0.94
Collagen fibril disruption occurs early in primary guinea pig knee osteoarthritis. Osteoarthritis Cartilage (2009) 0.93
Oxidative stress induces expression of osteoarthritis markers procollagen IIA and 3B3(-) in adult bovine articular cartilage. Osteoarthritis Cartilage (2008) 0.93
A comparison of five approaches to measurement of anatomic knee alignment from radiographs. Osteoarthritis Cartilage (2009) 0.93
Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. Osteoarthritis Cartilage (2012) 0.92
Gene expression analysis reveals HBP1 as a key target for the osteoarthritis susceptibility locus that maps to chromosome 7q22. Ann Rheum Dis (2012) 0.92
Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study. Osteoarthritis Cartilage (2008) 0.92
Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis. Eur Cell Mater (2015) 0.92
Structure of the type II collagen gene. Ann N Y Acad Sci (1985) 0.91
Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes. Osteoarthritis Cartilage (2010) 0.91
Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA. Osteoarthritis Cartilage (2009) 0.90
Association of knee and ankle osteoarthritis with physical performance. Osteoarthritis Cartilage (2011) 0.90
PIIANP and HELIXII diurnal variation. Osteoarthritis Cartilage (2008) 0.89
Type IIA procollagen in development of the human intervertebral disc: regulated expression of the NH(2)-propeptide by enzymic processing reveals a unique developmental pathway. Dev Dyn (2001) 0.89
Refined linkage mapping of a hip osteoarthritis susceptibility locus on chromosome 2q. Rheumatology (Oxford) (2002) 0.89
Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections. Ann Rheum Dis (2008) 0.88
Gene expression of type II collagens in chondro-osteophytes in experimental osteoarthritis. Osteoarthritis Cartilage (1997) 0.88
Expression of cartilage extracellular matrix and potential regulatory genes in a new human chondrosarcoma cell line. J Orthop Res (1998) 0.88
The 2.2-kb promoter of cartilage-derived retinoic acid-sensitive protein controls gene expression in cartilage and embryonic mammary buds of transgenic mice. Matrix Biol (2000) 0.88
Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study. Osteoarthritis Cartilage (2010) 0.88
Regulation of the mouse cartilage-derived retinoic acid-sensitive protein gene by the transcription factor AP-2. J Biol Chem (1998) 0.88
Expression of type II procollagens during development of the human intervertebral disc. Biochem Soc Trans (2002) 0.87
Early response of mouse joint tissue to noninvasive knee injury suggests treatment targets. Arthritis Rheumatol (2014) 0.87
Synovial fluid metabolites in osteonecrosis. Rheumatology (Oxford) (2006) 0.86
Modulation of extracellular matrix gene expression in bovine high-density chondrocyte cultures by ascorbic acid and enzymatic resuspension. Arch Biochem Biophys (1994) 0.86
Biosynthesis of small proteoglycan II (decorin) by chondrocytes and evidence for a procore protein. J Biol Chem (1991) 0.86
Deep sequencing of GDF5 reveals the absence of rare variants at this important osteoarthritis susceptibility locus. Osteoarthritis Cartilage (2011) 0.86
Failure of serum transforming growth factor-beta (TGF-beta1) as a biomarker of radiographic osteoarthritis at the knee and hip: a cross-sectional analysis in the Johnston County Osteoarthritis Project. Osteoarthritis Cartilage (2008) 0.85
Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. Osteoarthritis Cartilage (2008) 0.85
A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis. Osteoarthritis Cartilage (2007) 0.85