Histone ADP-ribosylation in DNA repair, replication and transcription.

Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol (2013) 2.71

The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks. Nat Struct Mol Biol (2012) 2.05

Site-specific incorporation of ε-N-crotonyllysine into histones. Angew Chem Int Ed Engl (2012) 1.13

The Elephant and the Blind Men: Making Sense of PARP Inhibitors in Homologous Recombination Deficient Tumor Cells. Front Oncol (2013) 1.10

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response. Genes Dev (2013) 1.09

The Promise of Proteomics for the Study of ADP-Ribosylation. Mol Cell (2015) 0.98

The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy. Oncogene (2014) 0.98

Essential role of poly(ADP-ribosyl)ation in cocaine action. Proc Natl Acad Sci U S A (2014) 0.97

The role of ADP-ribosylation in regulating DNA double-strand break repair. Cell Cycle (2012) 0.91

Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives. Curr Pharm Des (2013) 0.91

Chromatin dynamics during lytic infection with herpes simplex virus 1. Viruses (2013) 0.87

The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance. J Biol Chem (2014) 0.85

Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4. Epigenetics Chromatin (2013) 0.83

Initial characterization of histone H3 serine 10 O-acetylation. Epigenetics (2013) 0.82

Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation. Cell Death Dis (2016) 0.81

RNA Regulation by Poly(ADP-Ribose) Polymerases. Mol Cell (2015) 0.81

Pan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotype. Epigenetics Chromatin (2015) 0.81

Trial watch - inhibiting PARP enzymes for anticancer therapy. Mol Cell Oncol (2015) 0.79

Chromatin Remodeling and Transcriptional Control in Innate Immunity: Emergence of Akirin2 as a Novel Player. Biomolecules (2015) 0.79

Radiation-induced alterations in histone modification patterns and their potential impact on short-term radiation effects. Front Oncol (2012) 0.79

Serine is a new target residue for endogenous ADP-ribosylation on histones. Nat Chem Biol (2016) 0.78

Epigenetic enzymes are the therapeutic targets for CD4(+)CD25(+/high)Foxp3(+) regulatory T cells. Transl Res (2014) 0.78

Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation. J Biol Chem (2015) 0.77

A comprehensive view of the epigenetic landscape. Part II: Histone post-translational modification, nucleosome level, and chromatin regulation by ncRNAs. Neurotox Res (2014) 0.77

Computer-aided Molecular Design of Compounds Targeting Histone Modifying Enzymes. Comput Struct Biotechnol J (2015) 0.76

Erythropoietin-driven signalling and cell migration mediated by polyADP-ribosylation. Br J Cancer (2012) 0.76

PARty promoters: hormone-dependent gene regulation requires CDK2 activation of PARP1. Cell Cycle (2012) 0.75

An Overview of Chromatin-Regulating Proteins in Cells. Curr Protein Pept Sci (2016) 0.75

Potential role of epigenetic mechanisms in regulation of trophoblast differentiation, migration, and invasion in the human placenta. Cell Adh Migr (2016) 0.75

Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks. Sci Rep (2017) 0.75

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair. J Cell Sci (2016) 0.75

Coordinated Actions of MicroRNAs with other Epigenetic Factors Regulate Skeletal Muscle Development and Adaptation. Int J Mol Sci (2017) 0.75

ADP-ribose-specific chromatin-affinity purification for investigating genome-wide or locus-specific chromatin ADP-ribosylation. Nat Protoc (2017) 0.75

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell (2006) 8.48

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases. Front Biosci (2008) 3.56

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going? Microbiol Mol Biol Rev (2006) 3.31

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol (2009) 3.26

Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. Cell (2010) 2.52

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol Cell (2008) 2.29

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res (2009) 2.22

Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA. Mol Cell (2012) 1.93

Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription. J Biol Chem (2005) 1.93

Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proc Natl Acad Sci U S A (2011) 1.81

Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1. J Biol Chem (2003) 1.79

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1. Mol Cell Biol (2009) 1.79

Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression. EMBO J (2004) 1.74

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination. Nat Neurosci (2011) 1.67

PARP1 ADP-ribosylates lysine residues of the core histone tails. Nucleic Acids Res (2010) 1.64

The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res (2004) 1.63

SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310. J Cell Sci (2010) 1.60

Arginine methylation regulates DNA polymerase beta. Mol Cell (2006) 1.57

Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses. Mol Cell (2013) 1.52

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases. Nat Struct Mol Biol (2013) 1.47

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. Eur Heart J (2010) 1.40

PARP-1 and gene regulation: progress and puzzles. Mol Aspects Med (2013) 1.39

The peroxisome proliferator-activated receptor γ coactivator 1α/β (PGC-1) coactivators repress the transcriptional activity of NF-κB in skeletal muscle cells. J Biol Chem (2012) 1.32

Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res (2008) 1.32

PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase. Oncogene (2003) 1.30

The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. J Mol Biol (2005) 1.25

Histone acetyl transferases: a role in DNA repair and DNA replication. J Mol Med (Berl) (2002) 1.24

Acetylation regulates the DNA end-trimming activity of DNA polymerase beta. Mol Cell (2002) 1.22

SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis (2011) 1.19

Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest (2004) 1.17

Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes. Mol Cell (2012) 1.17

Protein arginine methyltransferase 1 coactivates NF-kappaB-dependent gene expression synergistically with CARM1 and PARP1. J Mol Biol (2008) 1.17

Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation. Int J Biochem Cell Biol (2008) 1.16

Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function. FASEB J (2009) 1.15

Localized insulin-like growth factor I delivery to enhance new bone formation. Bone (2003) 1.12

PARP1 is required for adhesion molecule expression in atherogenesis. Cardiovasc Res (2007) 1.06

The post-genomic era of interactive proteomics: facts and perspectives. Proteomics (2002) 1.06

NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biol Chem (2005) 1.06

Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression. BMC Genomics (2010) 1.05

Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging. Aging (Albany NY) (2009) 1.05

Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen. FASEB J (2006) 1.04

Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression. Mol Cancer Res (2008) 1.03

Enhancement of the efficiency of non-viral gene delivery by application of pulsed magnetic field. Nucleic Acids Res (2006) 1.01

p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization. J Cell Sci (2009) 1.01

MYBBP1a is a novel repressor of NF-kappaB. J Mol Biol (2006) 0.99

ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high-fat diet and impairs adipocyte function and differentiation. FASEB J (2012) 0.98

An epigenetic code for DNA damage repair pathways? Biochem Cell Biol (2005) 0.98

Yeast split-ubiquitin-based cytosolic screening system to detect interactions between transcriptionally active proteins. Biotechniques (2007) 0.96

Inhibition of ADP ribosylation prevents and cures helicobacter-induced gastric preneoplasia. Cancer Res (2010) 0.94

Poly(ADP-ribose)polymerase-1 (PARP1) controls adipogenic gene expression and adipocyte function. Mol Endocrinol (2011) 0.91

The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB. Nucleic Acids Res (2012) 0.90

CARM1 but not its enzymatic activity is required for transcriptional coactivation of NF-kappaB-dependent gene expression. J Mol Biol (2009) 0.88

Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways. Arthritis Res Ther (2013) 0.86

Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4. Epigenetics Chromatin (2013) 0.83

Artd1/Parp1 regulates reprogramming by transcriptional regulation of Fgf4 via Sox2 ADP-ribosylation. Stem Cells (2013) 0.83

Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation. Infect Immun (2010) 0.83

PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chem Biol (2013) 0.83

ARTD2 activity is stimulated by RNA. Nucleic Acids Res (2014) 0.82

Gene expression in synovial membrane cells after intraarticular delivery of plasmid-linked superparamagnetic iron oxide particles--a preliminary study in sheep. J Nanosci Nanotechnol (2006) 0.82

p65 controls NF-κB activity by regulating cellular localization of IκBβ. Biochem J (2011) 0.82

Poly(ADP-ribose) polymerase-1 protects from oxidative stress induced endothelial dysfunction. Biochem Biophys Res Commun (2011) 0.81

Identification of distinct amino acids as ADP-ribose acceptor sites by mass spectrometry. Methods Mol Biol (2011) 0.80

Genetic approaches to the identification of interactions between membrane proteins in yeast. J Recept Signal Transduct Res (2002) 0.80

Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS. BMC Cell Biol (2008) 0.80

SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress. Open Biol (2013) 0.79

Isolation, establishment, and characterization of ex vivo equine melanoma cell cultures. In Vitro Cell Dev Biol Anim (2008) 0.78

Identification of novel and cell type enriched cofactors of the transcription activation domain of RelA (p65 NF-kappaB). J Proteome Res (2005) 0.78

SnapShot: ADP-Ribosylation Signaling. Mol Cell (2016) 0.77

Poly(ADP-ribosyl)ation of methyl CpG binding protein 2 regulates chromatin structure. J Biol Chem (2016) 0.75

Chemoselective Dimerization of Phosphates. Org Lett (2016) 0.75