Published in Brain on July 08, 2011
Cytochrome P450 3A Enzymes Catalyze the O6-Demethylation of Thebaine, a Key Step in Endogenous Mammalian Morphine Biosynthesis. J Biol Chem (2015) 0.80
The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication. Front Cell Neurosci (2014) 0.80
Acute morphine treatments alleviate tremor in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys. PLoS One (2014) 0.79
Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology? Front Aging Neurosci (2014) 0.78
Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease. Proc Natl Acad Sci U S A (2015) 0.78
Comparison of serum and lithium-heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations. Br J Clin Pharmacol (2012) 0.76
Dopamine in the Brain: Hypothesizing Surfeit or Deficit Links to Reward and Addiction. J Reward Defic Syndr (2015) 0.75
Rat CYP2D2, not 2D1, is functionally conserved with human CYP2D6 in endogenous morphine formation. FEBS Lett (2012) 0.75
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat Genet (2003) 15.31
METLIN: a metabolite mass spectral database. Ther Drug Monit (2005) 10.15
Structural identification of a bacterial quorum-sensing signal containing boron. Nature (2002) 8.11
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet (2005) 7.66
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev (2007) 5.83
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med (2005) 3.26
The draft genome of a diploid cotton Gossypium raimondii. Nat Genet (2012) 3.18
Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges. Immunity (2011) 2.82
A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons. J Neurosci (2002) 2.71
Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med (2005) 2.55
A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol (2012) 2.54
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys. Ann Neurol (2014) 2.33
2-D structure of the A region of Xist RNA and its implication for PRC2 association. PLoS Biol (2010) 2.30
Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms. Lancet Neurol (2009) 2.28
Novel pharmacological targets for the treatment of Parkinson's disease. Nat Rev Drug Discov (2006) 2.23
Short telomeres and prognosis of hypertension in a chinese population. Hypertension (2009) 2.18
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Proc Natl Acad Sci U S A (2012) 2.16
Haemoglobin Noah Mehmet Oeztuerk (alpha(2) delta(2)143 (H21)His-->Tyr: A novel delta-chain variant in the 2,3-DPG binding site. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 2.05
p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell (2012) 2.04
Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Anal Chem (2006) 2.04
NaBC1 is a ubiquitous electrogenic Na+ -coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation. Mol Cell (2004) 2.02
Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem (2001) 1.97
Mammalian Scribble forms a tight complex with the betaPIX exchange factor. Curr Biol (2004) 1.89
Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration. Mult Scler (2010) 1.84
A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell (2013) 1.84
Phenotype associated with APP duplication in five families. Brain (2006) 1.83
Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences. Cell (2012) 1.81
Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum. Anal Chem (2006) 1.81
Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia. Ann Neurol (2010) 1.80
Hepatic fibrosis and cirrhosis: the (myo)fibroblastic cell subpopulations involved. Int J Biochem Cell Biol (2005) 1.79
Characterization of therapeutic antibodies and related products. Anal Chem (2012) 1.75
Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/BL6 mouse model. Proc Natl Acad Sci U S A (2012) 1.71
Sleep disorders in Parkinson's disease: the contribution of the MPTP non-human primate model. Exp Neurol (2009) 1.70
An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus. J Infect Dis (2013) 1.67
miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation. Brain Res Bull (2009) 1.66
Priorities in Parkinson's disease research. Nat Rev Drug Discov (2011) 1.66
Impairment of SLC17A8 encoding vesicular glutamate transporter-3, VGLUT3, underlies nonsyndromic deafness DFNA25 and inner hair cell dysfunction in null mice. Am J Hum Genet (2008) 1.65
Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia. Ann Neurol (2005) 1.65
Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders. Lancet Neurol (2009) 1.61
A tale of two oxidation states: bacterial colonization of arsenic-rich environments. PLoS Genet (2007) 1.59
Carcinogenic properties of proteins with pro-inflammatory activity from Streptococcus infantarius (formerly S.bovis). Carcinogenesis (2004) 1.58
The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone. Nat Neurosci (2008) 1.57
Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype. J Biol Chem (2007) 1.56
Variability of myocardial ischemic responses to mental versus exercise or adenosine stress in patients with coronary artery disease. J Nucl Cardiol (2008) 1.55
Recurrent mutations of MYD88 and TBL1XR1 in primary central nervous system lymphomas. Clin Cancer Res (2012) 1.54
Trends in glycosylation, glycoanalysis and glycoengineering of therapeutic antibodies and Fc-fusion proteins. Curr Pharm Biotechnol (2008) 1.53
Occupational and residential exposure to electromagnetic fields and risk of brain tumors in adults: a case-control study in Gironde, France. Int J Cancer (2011) 1.52
Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway. Nat Neurosci (2010) 1.52
Molecular classification of low-grade diffuse gliomas. Am J Pathol (2010) 1.51
Levodopa improves motor deficits but can further disrupt cognition in a macaque Parkinson model. Mov Disord (2012) 1.51
Gene clusters involved in anaerobic benzoate degradation of Geobacter metallireducens. Mol Microbiol (2005) 1.50
Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome. Gastroenterology (2009) 1.50
Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. Eur J Neurosci (2013) 1.49
Effect of prophylaxis on fungal infection and costs for high-risk liver transplant recipients. Liver Transpl (2007) 1.49
Biosimilar, biobetter, and next generation antibody characterization by mass spectrometry. Anal Chem (2012) 1.49
Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity. J Neurosci (2007) 1.48
A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype. EMBO J (2008) 1.47
Complete genome sequence of the nitrogen-fixing and rhizosphere-associated bacterium Pseudomonas stutzeri strain DSM4166. J Bacteriol (2011) 1.46
All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. Nat Struct Biol (2003) 1.46
Association of TLR4 gene non-missense single nucleotide polymorphisms with rheumatoid arthritis in Chinese Han population. Rheumatol Int (2012) 1.45
L-DOPA impairs proteasome activity in parkinsonism through D1 dopamine receptor. J Neurosci (2012) 1.43
Mental stress-induced myocardial ischemia in coronary artery disease patients with left ventricular dysfunction. J Nucl Cardiol (2007) 1.43
Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma. Proc Natl Acad Sci U S A (2011) 1.42
Repetitive oocyte donation does not decrease serum anti-Müllerian hormone levels. Fertil Steril (2009) 1.42
Coordinated reset has sustained aftereffects in Parkinsonian monkeys. Ann Neurol (2012) 1.42
The unique insert in myosin VI is a structural calcium-calmodulin binding site. Proc Natl Acad Sci U S A (2004) 1.38
A strategy for improving the room-temperature luminescence properties of Ru(II) complexes with tridentate ligands. J Am Chem Soc (2002) 1.38
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. Gastroenterology (2009) 1.37
Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol. Genome Res (2008) 1.36
The brown algal kelp Laminaria digitata features distinct bromoperoxidase and iodoperoxidase activities. J Biol Chem (2003) 1.35
RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease. J Neurosci (2007) 1.35
A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress. Biochem J (2002) 1.34
A comparison of the tube forming potentials of early and late endothelial progenitor cells. Exp Cell Res (2007) 1.32
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels. J Biol Chem (2011) 1.32
Differential pharmacological in vitro properties of organic cation transporters and regional distribution in rat brain. Neuropharmacology (2006) 1.30
Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease. Eur J Neurosci (2004) 1.30
VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. J Neurosci (2010) 1.29
Detection of viral agents in fecal specimens of monkeys with diarrhea. J Med Primatol (2007) 1.29
Proteomic analysis identifies novel proteins of the Maurer's clefts, a secretory compartment delivering Plasmodium falciparum proteins to the surface of its host cell. Mol Cell Proteomics (2005) 1.29
Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. Cell (2009) 1.28
Novel avian-origin human influenza A(H7N9) can be transmitted between ferrets via respiratory droplets. J Infect Dis (2013) 1.28
Lysosomal impairment in Parkinson's disease. Mov Disord (2013) 1.27
Dynamic behavior in diplatinum metalloreceptors. Inorg Chem (2002) 1.26
Transplantation of human bone marrow-derived mesenchymal stem cells promotes behavioral recovery and endogenous neurogenesis after cerebral ischemia in rats. Brain Res (2010) 1.26
Retinopathy online challenge: automatic detection of microaneurysms in digital color fundus photographs. IEEE Trans Med Imaging (2009) 1.26