Published in Int J Oncol on July 06, 2011
A preclinical evaluation of Minnelide as a therapeutic agent against pancreatic cancer. Sci Transl Med (2012) 1.84
Mouse models of pancreatic cancer. World J Gastroenterol (2012) 1.20
The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP. J Biol Chem (2012) 1.04
Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis. PLoS One (2012) 0.98
Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs. Breast Cancer Res Treat (2014) 0.91
Emodin reverses gemcitabine resistance in pancreatic cancer cells via the mitochondrial apoptosis pathway in vitro. Int J Oncol (2011) 0.78
Involvement of endoplasmic reticulum stress in capsaicin-induced apoptosis of human pancreatic cancer cells. Evid Based Complement Alternat Med (2013) 0.77
Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach. Biomed Res Int (2015) 0.77
Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab (2007) 6.91
Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature (2012) 6.65
Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature (2007) 4.00
Complementary function of the two catalytic domains of APOBEC3G. Virology (2005) 3.45
Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet (2012) 3.14
Progenitors of interstitial cells of cajal in the postnatal murine stomach. Gastroenterology (2008) 2.85
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol (2002) 2.83
Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A (2013) 2.76
The genome of the pear (Pyrus bretschneideri Rehd.). Genome Res (2012) 2.55
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis. Cell Metab (2009) 2.52
Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation (2007) 2.35
Safety of thoracoscopic lobectomy in locally advanced lung cancer. Ann Surg Oncol (2011) 2.34
Reduced stem cell factor links smooth myopathy and loss of interstitial cells of cajal in murine diabetic gastroparesis. Gastroenterology (2006) 2.26
Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J (2007) 2.25
Molecular intercommunication between the complement and coagulation systems. J Immunol (2010) 2.12
IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2. Cardiovasc Res (2004) 2.12
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation (2014) 2.07
The persistent circulation of enterovirus 71 in People's Republic of China: causing emerging nationwide epidemics since 2008. PLoS One (2011) 1.96
P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations. Chem Rev (2010) 1.95
Macrophages are required for neonatal heart regeneration. J Clin Invest (2014) 1.93
A conformational switch in vinculin drives formation and dynamics of a talin-vinculin complex at focal adhesions. J Biol Chem (2006) 1.90
Optical coherence elastography of engineered and developing tissue. Tissue Eng (2006) 1.86
c-kit gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors. J Gastroenterol Hepatol (2003) 1.84
Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin. J Biol Chem (2005) 1.79
Spectroscopic spectral-domain optical coherence microscopy. Opt Lett (2006) 1.77
Analysis of oral microbiota in children with dental caries by PCR-DGGE and barcoded pyrosequencing. Microb Ecol (2010) 1.77
Insulin and the insulin receptor in experimental models of learning and memory. Eur J Pharmacol (2004) 1.74
The immune protein CD3zeta is required for normal development of neural circuits in the retina. Neuron (2010) 1.74
7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development. Proc Natl Acad Sci U S A (2009) 1.71
Beta-nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle. Proc Natl Acad Sci U S A (2007) 1.71
A one-step homogeneous immunoassay for cancer biomarker detection using gold nanoparticle probes coupled with dynamic light scattering. J Am Chem Soc (2008) 1.67
Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance. Diabetes (2008) 1.65
Methamphetamine enhances HIV infection of macrophages. Am J Pathol (2008) 1.60
FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity. J Biol Chem (2006) 1.56
Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo. Am J Physiol Heart Circ Physiol (2004) 1.56
Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice. Am J Physiol Endocrinol Metab (2007) 1.55
Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria. Blood (2014) 1.55
Proteasome substrate degradation requires association plus extended peptide. EMBO J (2006) 1.54
Ischemic postconditioning attenuates renal ischemic/reperfusion injury in mongrel dogs. Urology (2010) 1.53
A randomized trial of transvesical prostatectomy versus transurethral resection of the prostate for prostate greater than 80 mL. Urology (2010) 1.52
Urodynamically diagnosed detrusor hypocontractility: should transurethral resection of the prostate be contraindicated? Int Urol Nephrol (2011) 1.52
Xenopus actin-interacting protein 1 (XAip1) enhances cofilin fragmentation of filaments by capping filament ends. J Biol Chem (2002) 1.50
Management of wounds with exposed bone structures using an artificial dermis and skin grafting technique. J Plast Reconstr Aesthet Surg (2009) 1.49
Significant effect of size on the in vivo biodistribution of gold composite nanodevices in mouse tumor models. Nanomedicine (2007) 1.49
C/EBP transcription factors mediate epicardial activation during heart development and injury. Science (2012) 1.48
Ischemic postconditioning inhibits apoptosis after focal cerebral ischemia/reperfusion injury in the rat. Stroke (2008) 1.47
Impact of red blood cell distribution width on long-term mortality in patients with ST-elevation myocardial infarction. Cardiology (2014) 1.44
Treatment of venous infraorbital dark circles using a long-pulsed 1,064-nm neodymium-doped yttrium aluminum garnet laser. Dermatol Surg (2012) 1.44
Prevention of contrast-induced nephropathy with ascorbic acid. Intern Med (2012) 1.44
Retracted Meta-analysis of the effect of percutaneous coronary intervention on chronic total coronary occlusions. J Cardiothorac Surg (2014) 1.43
Formation of actin-ADF/cofilin rods transiently retards decline of mitochondrial potential and ATP in stressed neurons. Am J Physiol Cell Physiol (2006) 1.43
Retracted Targeting 3-phosphoinoside-dependent kinase-1 to inhibit insulin-like growth factor-I induced AKT and p70 S6 kinase activation in breast cancer cells. PLoS One (2012) 1.41
Influence of arbuscular mycorrhizae on photosynthesis and water status of maize plants under salt stress. Mycorrhiza (2008) 1.40
New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties. Immunobiology (2012) 1.39
An instructive role for patterned spontaneous retinal activity in mouse visual map development. Neuron (2011) 1.38
Defective in Tapetal development and function 1 is essential for anther development and tapetal function for microspore maturation in Arabidopsis. Plant J (2008) 1.38
Erythroid dysplasia, megaloblastic anemia, and impaired lymphopoiesis arising from mitochondrial dysfunction. Blood (2009) 1.37
Selective recruitment of regulatory T cell through CCR6-CCL20 in hepatocellular carcinoma fosters tumor progression and predicts poor prognosis. PLoS One (2011) 1.34
Expression pattern, regulation, and functions of methionine adenosyltransferase 2beta splicing variants in hepatoma cells. Gastroenterology (2007) 1.30
Rational design of 4,5-disubstituted-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-ones as a novel class of inhibitors of epidermal growth factor receptor (EGF-R) and Her2(p185(erbB)) tyrosine kinases. Bioorg Med Chem Lett (2002) 1.30
Orientation-selective responses in the mouse lateral geniculate nucleus. J Neurosci (2013) 1.30
A Phos-tag-based approach reveals the extent of physiological endoplasmic reticulum stress. PLoS One (2010) 1.29
Proteomic analysis of rice (Oryza sativa) seeds during germination. Proteomics (2007) 1.29
Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway. Cell Signal (2011) 1.28
The substantial hospitalization burden of influenza in central China: surveillance for severe, acute respiratory infection, and influenza viruses, 2010-2012. Influenza Other Respir Viruses (2013) 1.28
TGFβ signaling plays a critical role in promoting alternative macrophage activation. BMC Immunol (2012) 1.27
The cystic fibrosis transmembrane conductance regulator in reproductive health and disease. J Physiol (2008) 1.26
High pulsatility flow induces adhesion molecule and cytokine mRNA expression in distal pulmonary artery endothelial cells. Ann Biomed Eng (2009) 1.26
XBP-1 couples endoplasmic reticulum stress to augmented IFN-beta induction via a cis-acting enhancer in macrophages. J Immunol (2010) 1.26
Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE. J Clin Invest (2014) 1.24
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol (2011) 1.24
Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells. Mol Endocrinol (2002) 1.23
Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. J Clin Invest (2009) 1.22
Detection of tissue harmonic motion induced by ultrasonic radiation force using pulse-echo ultrasound and Kalman filter. IEEE Trans Ultrason Ferroelectr Freq Control (2007) 1.22
Microendoscopic discectomy for lumbar disc herniation: surgical technique and outcome in 873 consecutive cases. Spine (Phila Pa 1976) (2006) 1.22
Flexible quantum private queries based on quantum key distribution. Opt Express (2012) 1.22
Renal NF-kappaB activation and TNF-alpha upregulation correlate with salt-sensitive hypertension in Dahl salt-sensitive rats. Am J Physiol Regul Integr Comp Physiol (2006) 1.22
BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. J Neurosci (2009) 1.22
Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. Am J Physiol Lung Cell Mol Physiol (2008) 1.22
Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial. Arch Intern Med (2003) 1.21
A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1. Cancer Cell (2013) 1.21
Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}. J Biol Chem (2009) 1.21
Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26. Nucleic Acids Res (2010) 1.21
Genome-wide identification of Schistosoma japonicum microRNAs using a deep-sequencing approach. PLoS One (2009) 1.20
Exploring the mechanism of Physcomitrella patens desiccation tolerance through a proteomic strategy. Plant Physiol (2009) 1.19
TACE is required for fetal murine cardiac development and modeling. Dev Biol (2003) 1.19
Is thoracoscopic pneumonectomy safe? Ann Thorac Surg (2009) 1.18
U2AF participates in the binding of TAP (NXF1) to mRNA. J Biol Chem (2001) 1.18
Genome analysis and signature discovery for diving and sensory properties of the endangered Chinese alligator. Cell Res (2013) 1.18
Emerging roles for XBP1, a sUPeR transcription factor. Gene Expr (2010) 1.17
Attenuation of reperfusion injury by renal ischemic postconditioning: the role of NO. Biochem Biophys Res Commun (2007) 1.16
Nucleic acid aptamers for biosensors and bio-analytical applications. Analyst (2009) 1.16
Memory IL-22-producing CD4+ T cells specific for Candida albicans are present in humans. Eur J Immunol (2009) 1.15
Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway. Circulation (2009) 1.15
Evaluating total lymphocyte count as a surrogate marker for CD4 cell count in the management of HIV-infected patients in resource-limited settings: a study from China. PLoS One (2013) 1.15
Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway. Circulation (2007) 1.15
Sustained ocular hypertension induces dendritic degeneration of mouse retinal ganglion cells that depends on cell type and location. Invest Ophthalmol Vis Sci (2013) 1.15
Changes in the structure and function of ICC networks in ICC hyperplasia and gastrointestinal stromal tumors. Gastroenterology (2008) 1.14